Optical fiber balloon catheter

Abstract

The utility model discloses an optical fiber balloon catheter which comprises the following components: a catheter which comprises an inner tube and an outer tube, and the inner tube passes through the inner part of the outer tube; the balloon is located on the periphery of the far end of the catheter and can expand in the radial direction relative to the catheter, and a vascular repair promoting coating is arranged on the outer surface of the balloon; the inner tube comprises a far-end inner tube section located in the balloon, and a groove is formed in the outer wall of the far-end inner tube section; the near end of the optical fiber is connected to the laser generator, and the far end of the optical fiber is provided with a light-emitting section extending into the balloon; and the light-emitting section is embedded in the groove. The groove is formed in the outer wall of the inner tube, and the optical fiber is embedded in the groove, so that light emitted by the optical fiber can be uniformly irradiated to the surface of the balloon, the vascular repair promoting coating is activated, crosslinking of protein in the vascular wall is triggered, a natural vascular stent is formed, and the expanded blood vessel is maintained. The space occupied by the optical fiber in the radial direction of the balloon is small, the overall outer diameter of the balloon before expansion can be reduced, and the trafficability of the balloon catheter is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of interventional medical instrument, concretely relates to a kind of optical fiber balloon catheter. BACKGROUND

[0002] Vascular intervention treatment is an important treatment mode for vascular stenosis. For intravascular stenosis, balloon dilatation or stent implantation is usually used for treatment, but both have their own shortcomings. After balloon dilatation surgery, the expanded arterial segment is prone to endothelial damage and elastic fiber fracture, which leads to thrombosis and intimal hyperplasia. Moreover, the balloon has a short inflation time during use, and the blood vessel wall lacks long-term support, leading to elastic recoil and remodeling of the blood vessel wall. Blood vessel stents placed in blood vessels for a long time will cause the body to proliferate in response to foreign bodies, leading to restenosis in the blood vessel stent.

[0003] To solve the above problems, a balloon catheter with optical fiber is provided, which is coated with a vascular repair promoting coating on the outer surface of the balloon. After balloon dilatation, the drug in the vascular repair promoting coating is released into the blood vessel wall, and a specific wavelength of light is emitted through the optical fiber to activate and induce amino acid formation in the blood vessel wall. Covalent cross-linking occurs, providing support to the blood vessel and preventing blood vessel recoil.

[0004] However, the existing balloon catheter with optical fiber usually places the optical fiber on the outer wall of the inner tube inside the balloon. The placement of the optical fiber inside the balloon increases the overall outer diameter of the balloon before expansion, affecting the passability of the balloon catheter. SUMMARY

[0005] Therefore, the utility model provides a kind of optical fiber balloon catheter to solve the problem that the passability of the balloon catheter is poor due to the large space occupied by the optical fiber in the existing optical fiber balloon catheter.

[0006] To solve the above technical problems, the technical scheme of the utility model is as follows:

[0007] A kind of optical fiber balloon catheter, comprising:

[0008] A catheter comprising an inner tube and an outer tube, the inner tube passing through the inside of the outer tube;

[0009] A balloon located on the outer periphery of the distal end of the catheter and capable of radial expansion relative to the catheter, the outer surface of the balloon being provided with a vascular repair promoting coating;

[0010] The inner tube includes a distal end inner tube segment located inside the balloon, and a groove is provided on the outer wall of the distal end inner tube segment;

[0011] An optical fiber, a proximal end of the optical fiber is connected to a laser generator, a distal end of the optical fiber has a light emitting segment extending into the balloon; the light emitting segment is embedded on the groove.

[0012] Further, the groove extends from a proximal end of the distal end inner tube segment to a distal end of the distal end inner tube segment, the light emitting segment extends in the same direction as the groove.

[0013] Further, the groove is a straight line groove in a straight line shape, a plurality of the straight line grooves are uniformly arranged along a circumference of the distal end inner tube segment, and each of the straight line grooves is embedded with a light emitting segment of one of the optical fibers.

[0014] Further, the groove is a spiral groove in a spiral shape.

[0015] Further, the groove is a curved groove in a curved shape, a plurality of the curved grooves are uniformly arranged along a circumference of the distal end inner tube segment, and each of the curved grooves is embedded with a light emitting segment of one of the optical fibers.

[0016] Further, a part of the light emitting segment is embedded in the groove, and another part of the light emitting segment protrudes outward from the outer circumferential wall of the inner tube.

[0017] Further, in a radial cross-sectional direction of the inner tube, a light emitting surface of the part of the light emitting segment protruding outward from the outer circumferential wall of the inner tube is in an arc shape.

[0018] Further, when the balloon is in a filled state, the light emitted by the light emitting segment is uniformly irradiated on an inner surface of the balloon.

[0019] Further, the light emitted by the light emitting segment is in a wavelength of 400nm-500nm.

[0020] Further, a catheter seat is further included, the catheter seat is provided with a balloon filling interface and an optical fiber outlet; proximal ends of the inner tube and the outer tube are connected to the catheter seat; a filling channel is formed between the inner tube and the outer tube, the balloon filling interface is in communication with an inner cavity of the balloon through the filling channel; a proximal end of the optical fiber is connected to the laser generator after being led out from the optical fiber outlet.

[0021] Further, the pro-vascular repair coating contains a pro-vascular repair drug, the pro-vascular repair drug is a naphthalimide dimer and its derivative.

[0022] Further, an outer surface of the balloon is provided with a blood vessel restenosis inhibiting drug coating containing a blood vessel restenosis inhibiting drug; the blood vessel restenosis inhibiting drug is any one or more of a macrolide immunosuppressant, a macrolide antibiotic, rapamycin, a structural derivative and a functional analogue of rapamycin, everolimus, a structural derivative and a functional analogue of everolimus, paclitaxel, a taxane, temsirolimus, zotarolimus, everolimus, sirolimus, biolimus, tacrolimus, temsirolimus, a temsirolimus compound, a zotarolimus compound, an everolimus compound, a sirolimus compound, a biolimus compound, tacrolimus, a temsirolimus compound.

[0023] The technical scheme of the utility model has the following advantages: when in use, the light emitted by the light-emitting section of the optical fiber can irradiate the surface of the balloon, so that the blood vessel repair promoting coating is activated, cross-linking of the protein in the blood vessel wall is induced, a natural blood vessel stent is formed, the blood vessel is supported, the expanded blood vessel can be maintained, and the problem of shrinkage of the blood vessel after balloon expansion treatment is avoided. BRIEF DESCRIPTION OF DRAWINGS

[0024] In order to more clearly illustrate the specific embodiments of the utility model or the technical scheme in the prior art, the drawings needed in the specific embodiments or the prior art description will be briefly introduced as follows, and obviously, the drawings in the following description are some embodiments of the utility model, and for those skilled in the art, other drawings can also be obtained according to these drawings without creative labor.

[0025] Figure 1 It is a whole structure schematic view of the optical fiber balloon catheter in the utility model embodiment one;

[0026] Figure 2 It is a connection structure schematic view of the balloon, the inner tube and the optical fiber in the utility model embodiment one, wherein the balloon is in the full state;

[0027] Figure 3 It is a front view of Figure 2

[0028] Figure 4 It is a sectional view of A-A surface in Figure 3

[0029] ​​Figure 5 for Figure 3 A sectional view of plane B-B in the middle;

[0030] Figure 6 This is a schematic diagram of the inner tube in Embodiment 1 of this utility model;

[0031] Figure 7 This is a cross-sectional view of the inner tube in Embodiment 1 of this utility model;

[0032] Figure 8 This is a schematic diagram of the connection structure of the balloon, inner tube and optical fiber in Embodiment 2 of this utility model, wherein the balloon is in an inflated state;

[0033] Figure 9 for Figure 8 The front view;

[0034] Figure 10 for Figure 9 A sectional view of plane A-A in the middle;

[0035] Figure 11 for Figure 9 A sectional view of plane B-B in the middle;

[0036] Figure 12 This is a schematic diagram of the connection structure between the optical fiber and the inner tube in Embodiment 2 of this utility model;

[0037] Figure 13 for Figure 12 The front view;

[0038] Figure 14 for Figure 13 A sectional view of plane A-A in the middle;

[0039] Figure 15 for Figure 13 A sectional view of plane B-B in the middle;

[0040] Figure 16 This is a schematic diagram of the connection structure of the balloon, inner tube and optical fiber in Embodiment 3 of this utility model, wherein the balloon is in an inflated state;

[0041] Figure 17 for Figure 16 The front view;

[0042] Figure 18 for Figure 17 A sectional view of plane A-A in the middle;

[0043] Figure 19 for Figure 17 A sectional view of plane B-B in the middle;

[0044] Figure 20 This is a schematic diagram of the connection structure between the optical fiber and the inner tube in Embodiment 3 of this utility model;

[0045] Figure 21 is a front view of the device of Figure 20

[0046] Figure 22 is a cross-sectional view of the device of Figure 21

[0047] Figure 23 is a cross-sectional view of the device of Figure 21

[0048] 1, catheter; 11, inner tube; 11a, distal inner tube segment; 11b, proximal inner tube segment; 12, groove; 121, straight groove; 122, spiral groove; 123, curved groove; 13, tip tube; 2, balloon; 3, catheter seat; 31, balloon inflation interface; 32, guide wire outlet; 33, optical fiber outlet; 4, optical fiber; 41, light emitting segment; 5, laser generator. DETAILED DESCRIPTION

[0049] The technical solutions of the present application will be described clearly and completely below in conjunction with the drawings. Obviously, the described embodiments are only some of the embodiments of the present application, rather than all the embodiments. Based on the embodiments of the present application, all the other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0050] In the description of the present application, it should be understood that the terms "proximal end" and "distal end" throughout the description refer to the proximal and distal ends relative to the operator. In use, the end close to the doctor or operator is the "proximal end", i.e. the end where the operator is located, and the end away from the doctor or operator is the "distal end", i.e. the end where the balloon is located. The above description of the orientation is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply that the device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application.

[0051] Embodiment one

[0052] As Figure 1 - Figure 7 ​​​An optical fiber balloon catheter is shown, which comprises a catheter 1, a balloon 2, a catheter seat 3, an optical fiber 4 and a laser generator 5. The catheter 1 has a balloon inflation channel, a guide wire channel and an optical fiber channel therein. The balloon 2 is connected to the outer periphery of the distal end of the catheter 1, and the balloon 2 can be radially expanded relative to the catheter 1; the outer surface of the balloon 2 is provided with a blood vessel repair promoting coating. The catheter seat 3 is connected to the proximal end of the catheter 1, and the catheter seat 3 is provided with a balloon inflation interface 31, a guide wire outlet 32 and an optical fiber outlet 33; the balloon inflation interface 31 is in communication with the inner cavity of the balloon 2 through the balloon inflation channel in the catheter 1, the guide wire outlet 32 is in communication with the guide wire channel in the catheter 1, and the optical fiber outlet 33 is in communication with the optical fiber channel in the catheter 1. The proximal end of the optical fiber 4 is connected to the external laser generator 5 after being led out from the optical fiber outlet 33, and the distal end of the optical fiber 4 extends to the inside of the balloon 2 through the optical fiber channel in the catheter 1.

[0053] Specifically, the catheter 1 comprises an inner tube 11, an outer tube (not shown in the figure) and a terminal tube 13; the inner tube 11 passes through the inside of the outer tube, and the terminal tube 13 is connected to the distal end of the inner tube 11. The distal end of the balloon 2 is connected to the inner tube 11, and the proximal end of the balloon 2 is connected to the outer tube; the inner tube 11 penetrates through the balloon 2, and the proximal end of the inner tube 11 and the proximal end of the outer tube are both connected to the catheter seat 3. The channel formed between the inner tube 11 and the outer tube is the balloon inflation channel. The inner cavity of the inner tube 11 is the guide wire channel for the guide wire to pass through, and the distal end of the guide wire is connected to the terminal tube 13; the guide wire passes through the guide wire channel in the inner tube 11 and is led out from the guide wire outlet 32, and the guide wire is used to deliver the optical fiber balloon catheter to the lesion site.

[0054] In some embodiments, the inner tube 11 comprises a distal end inner tube segment 11a located inside the balloon 2 and a proximal end inner tube segment 11b located outside the balloon 2; a groove 12 is arranged on the outer wall of the distal end inner tube segment 11a, and the groove 12 on the distal end inner tube segment 11a extends to the outer wall of the proximal end inner tube segment 11b, that is, the groove 12 extends from the proximal end of the inner tube 11 to the distal end of the inner tube 11. The space in the groove 12 is the optical fiber channel; the optical fiber 4 is embedded on the groove 12, and the extension direction of the optical fiber 4 is the same as the extension direction of the groove 12. It should be noted here that the distal end inner tube segment 11a and the proximal end inner tube segment 11b are only divided according to the positional relationship between the inner tube 11 and the balloon 2, and the distal end inner tube segment 11a and the proximal end inner tube segment 11b are actually an integral tube. In alternative embodiments, the groove 12 is only arranged on the outer wall of the distal end inner tube segment 11a, and the outer wall of the proximal end inner tube segment 11b is not provided with the groove 12, and the optical fiber channel is arranged in the wall of the proximal end inner tube segment 11b.

[0055] In some embodiments, a part of the light emitting section 41 is embedded in the groove 12, and another part protrudes outward from the outer circumferential wall of the inner tube 11; in the radial cross-sectional direction of the inner tube 11, the light emitting surface of the part of the light emitting section 41 protruding outward relative to the outer circumferential wall of the inner tube 11 is arc-shaped. In this way, when the balloon 2 is in the inflated state, the light emitted by the light emitting section 41 can be uniformly irradiated on the inner surface of the balloon 2.

[0056] In some embodiments, the groove 12 on the outer wall of the distal inner tube section 11a extends from the proximal end of the distal inner tube section 11a to the distal end of the distal inner tube section 11a, and the extension direction of the light emitting section 41 is the same as the extension direction of the groove 12. Specifically, the groove 12 is a straight linear groove in a straight line shape, the length extension direction of the straight linear groove is the same as the length extension direction of the inner tube 11; the straight linear groove is uniformly provided with four straight lines along the circumference of the distal inner tube section 11a, the included angle between the two adjacent straight lines is 90 degrees, and each straight line is embedded with a light emitting section 41 of an optical fiber 4. It can be understood here that the number of straight linear grooves can also be three, five or more than five.

[0057] The wavelength of the light emitted by the optical fiber 4 is 400-500 nm. The pro-vascular repair coating contains a pro-vascular repair drug, and the pro-vascular repair drug is a naphthalimide dimer and its derivatives.

[0058] In some embodiments, the outer surface of the balloon 2 is provided with a blood vessel restenosis inhibiting drug coating, and the blood vessel restenosis inhibiting drug coating contains a blood vessel restenosis inhibiting drug; the blood vessel restenosis inhibiting drug is any one or more of a macrolide immunosuppressant, a macrolide antibiotic, rapamycin, a structural derivative and a functional analogue of rapamycin, everolimus, a structural derivative and a functional analogue of everolimus, paclitaxel, a taxane, temsirolimus, zotarolimus, everolimus, sirolimus, biolimus, tacrolimus, temsirolimus, a temsirolimus compound, a zotarolimus compound, an everolimus compound, a sirolimus compound, a biolimus compound, tacrolimus, a temsirolimus compound.

[0059] The light emitted by the light emitting section 41 of the optical fiber 4 can irradiate the surface of the balloon 2 after the balloon 2 reaches the target position and is radially expanded, so that the pro-vascular repair coating containing the pro-vascular repair drug is activated, the cross-linking of the proteins in the blood vessel wall is induced, the natural blood vessel stent is formed, the blood vessel is supported, the expanded blood vessel is maintained, and the problem of blood vessel shrinkage after balloon expansion treatment is avoided. By arranging the groove 12 on the outer wall of the distal end inner tube section 11a of the inner tube 11 located in the balloon 2, the light emitting section 41 at the distal end of the optical fiber 4 is embedded in the groove 12. In this way, the space occupied by the optical fiber 4 in the radial direction of the catheter 1 can be reduced, which is beneficial to reducing the overall outer diameter of the balloon 2 before expansion and improving the passability of the balloon catheter. In addition, the structure design of the light emitting section 41 embedded in the groove 12 can also improve the stability of the installation position of the light emitting section 41, and then the light emitted by the optical fiber 4 can uniformly irradiate the surface of the balloon 2.

[0060] Embodiment two

[0061] As shown in Figure 8 - Figure 15 An optical fiber balloon catheter, which is different from the first embodiment, is shown in the figure. The groove 12 is a spiral groove, and the spiral groove is embedded with a light emitting section 41 of an optical fiber 4. The shape of the light emitting section 41 is the same as that of the spiral groove. The proximal end of the optical fiber 4 is drawn out from the optical fiber outlet 33 on the catheter 1 seat and connected to the external laser generator 5. In this way, only one optical fiber 4 can make the light irradiate each part of the surface of the balloon 2, so that the pro-vascular repair drug on each part of the surface of the balloon 2 can be activated by light and induce the cross-linking of the proteins in the blood vessel wall.

[0062] Embodiment three

[0063] As shown in Figure 16 - Figure 23 An optical fiber balloon catheter, which is different from the first embodiment, is shown in the figure. The groove 12 is a spiral groove, and the spiral groove is embedded with a light emitting section 41 of an optical fiber 4. The shape of the light emitting section 41 is the same as that of the spiral groove. The proximal end of the optical fiber 4 is drawn out from the optical fiber outlet 33 on the catheter 1 seat and connected to the external laser generator 5. In this way, only one optical fiber 4 can make the light irradiate each part of the surface of the balloon 2, so that the pro-vascular repair drug on each part of the surface of the balloon 2 can be activated by light and induce the cross-linking of the proteins in the blood vessel wall.

[0064] In summary, the optical fiber balloon catheter provided by the embodiment of the present application has the following advantages: the recess 12 is arranged on the outer wall of the distal end inner tube segment 11a of the inner tube 11 located in the balloon 2, and the light emitting segment 41 of the optical fiber 4 is embedded on the recess 12, so that the space occupied by the light emitting segment 41 in the radial direction of the catheter 1 can be reduced, the overall outer diameter of the balloon 2 before expansion can be reduced, and the passability of the balloon catheter can be improved; in addition, the structure design that the light emitting segment 41 is embedded in the recess 12 can improve the stability of the installation position of the light emitting segment 41, so that the light emitted by the optical fiber 4 can be uniformly irradiated on the surface of the balloon 2; the light can activate the vascular repair promoting drug in the vascular repair promoting coating on the surface of the balloon 2, induce the cross-linking of the protein in the blood vessel wall, form a natural blood vessel stent, support the blood vessel, maintain the expanded blood vessel, and avoid the problem that the blood vessel shrinks after balloon expansion treatment.

[0065] Obviously, the above embodiments are only examples for clearly illustrating the present application, and are not intended to limit the embodiments. Based on the above description, other different forms of changes or variations can be made by those skilled in the art. All the embodiments do not need to be exhausted, and the obvious changes or variations derived therefrom are still within the protection scope of the present application.

Claims

1. A fiber-optic balloon catheter, characterized by, The catheter (1) comprises an inner tube (11) and an outer tube, the inner tube (11) passing through the inner part of the outer tube; A balloon (2) is located at the outer periphery of the distal end of the catheter (1) and can be radially expanded relative to the catheter (1), the outer surface of the balloon (2) being provided with a vascular repair promoting coating; The inner tube (11) comprises a distal end inner tube segment (11a) located in the balloon (2), and a groove (12) is provided on the outer wall of the distal end inner tube segment (11a); An optical fiber (4) has its proximal end connected to a laser generator (5), and its distal end has a light emitting segment (41) extending into the interior of the balloon (2); the light emitting segment (41) is embedded in the groove (12). The groove (12) extends from the proximal end of the distal end inner tube segment (11a) to the distal end of the distal end inner tube segment (11a), and the extension direction of the light emitting segment (41) is the same as that of the groove (12).

2. The optical fiber balloon catheter of claim 1, wherein, The groove (12) is a straight groove in a straight line shape, and a plurality of straight grooves are uniformly arranged along the circumference of the distal end inner tube segment (11a), and each straight groove is embedded with a light emitting segment (41) of an optical fiber (4).

3. The optical fiber balloon catheter of claim 2, wherein, The groove (12) is a spiral groove in a spiral shape.

4. The optical fiber balloon catheter of claim 2, wherein, The groove (12) is a curved groove in a curved shape, and a plurality of curved grooves are uniformly arranged along the circumference of the distal end inner tube segment (11a), and each curved groove is embedded with a light emitting segment (41) of an optical fiber (4).

5. The optical fiber balloon catheter of claim 2, wherein, Part of the light emitting segment (41) is embedded in the groove (12), and the other part protrudes outward from the outer peripheral wall of the inner tube (11).

6. The optical fiber balloon catheter of any of claims 1-5, wherein, The inner tube (11) further comprises a proximal end inner tube segment (11b) located outside the balloon (2), and the groove (12) extends to the outer wall of the proximal end inner tube segment (11b); the part of the optical fiber (4) located outside the proximal end inner tube segment (11b) is embedded in the groove on the outer wall of the proximal end inner tube segment (11b).

7. The optical fiber balloon catheter of any of claims 1-5, wherein, A catheter seat (3) is further provided, which is provided with a balloon inflation interface (31), a guide wire outlet (32) and an optical fiber outlet (33); the proximal ends of the inner tube (11) and the outer tube are connected to the catheter seat (3); the channel formed between the inner tube (11) and the outer tube is a balloon inflation channel, the balloon inflation interface (31) is in communication with the inner cavity of the balloon (2) through the balloon inflation channel; the cavity in the inner tube (11) is a guide wire channel, which is in communication with the guide wire outlet (32); the proximal end of the optical fiber (4) is connected to the laser generator (5) after being led out from the optical fiber outlet (33).

8. The optical fiber balloon catheter of any of claims 1-5, wherein, The vascular repair promoting coating contains a vascular repair promoting drug, and the vascular repair promoting drug is a naphthalimide dimer and its derivative.

9. The optical fiber balloon catheter of any of claims 1-5, wherein, ​

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