ELISA kit reaction control device

Abstract

The utility model discloses an ELISA (Enzyme Linked Immunosorbent Assay) kit reaction control device which comprises a box body, a supporting plate, an electric push rod and a mounting roller, a linear motor is fixedly connected to the top end in the box body, a manipulator is fixedly connected to the output end of the linear motor, an ELISA kit is mounted at the bottom end in the box body, a supporting column is rotationally connected to the interior of the box body, and the supporting column is fixedly connected to the output end of the linear motor. The push plate is driven by the electric push rod to extrude the silica gel sealing gasket, so that the silica gel layer is tightly attached to the top end of the ELISA kit, liquid evaporation in the reaction process can be effectively prevented, and detection result deviation caused by sample concentration change is avoided; the silica gel layer of the silica gel sealing gasket has good elasticity and sealing performance, and is matched with the pressure effect of the push plate, so that the problems of poor fitting degree of manual sealing film covering and untight sealing of a simple cover plate in the prior art are solved, the sealing reliability of a reaction system is remarkably improved, and a powerful guarantee is provided for the accuracy of a detection result.

Description

TECHNICAL FIELD

[0001] The utility model relates to ELISA kit reaction technical field, concretely is a kind of ELISA kit reaction control device. BACKGROUND

[0002] As a kind of sensitivity high, specific strong immune detection method, ELISA technique has been widely used in clinical diagnosis, food safety detection, environmental monitoring etc.;In the ELISA reaction process, reagent kit needs to be incubated under the specific constant temperature condition in reaction liquid body, the sealing property of reaction system is crucial at this time;If not properly sealed, it is easy to cause reaction liquid evaporation, causes sample concentration change, detects the problem such as result deviation, seriously influence the accuracy and reliability of detection;

[0003] In prior art, the sealing mode of ELISA reagent kit is mostly artificial covering sealing film or using simple cover plate;Artificial covering sealing film not only is tedious, inefficient, difficult to adapt to high-throughput detection demand, and the adhesion of sealing film is difficult to guarantee, and wrinkle, leakage and other situations are prone to occur;Simple cover plate can realize sealing to a certain extent, but often cannot adapt to different specifications of ELISA reagent kit, and the sealing property between cover plate and reagent kit is poor, still exist the risk of liquid evaporation;

[0004] At the same time, when needing to seal multiple ELISA reagent kits at different positions, existing device is difficult to realize the rapid and accurate displacement of sealing component, usually needs manual adjustment reagent kit position or replace sealing component, operation flexibility is poor, further reduce detection efficiency;In addition, existing sealing component is mostly fixed connection mode, when sealing component needs to be replaced due to wear and tear, pollution, the process of disassembly and installation is complex, time-consuming is longer, it is not conducive to the maintenance and continuous use of equipment.

[0005] Therefore, we propose a kind of ELISA kit reaction control device. Utility model content

[0006] The utility model aims at providing a kind of ELISA kit reaction control device, to solve the problems raised in the above background.

[0007] In order to achieve the above object, the utility model provides the following technical scheme: an ELISA kit reaction control device, including box, support plate, electric push rod and installation roll, the inside top fixed connection of box has linear motor, the output fixed connection of linear motor has manipulator, the inside bottom of box is installed with ELISA kit, the inside rotation connection of box has support column, the top fixed connection of support column has support plate, the one side of support plate is installed with silica gel gasket, the inside fixed connection of support plate has electric push rod, the output fixed connection of electric push rod has push board, the one side of push board contacts silica gel gasket, the back surface symmetrical installation of support plate has installation roll, two installation rolls are installed with silica gel gasket two ends cooperation respectively.

[0008] Preferably, the silica gel gasket is divided into a silica gel layer and a adhesive tape layer, the silica gel layer is adhered to the adhesive tape layer, and the adhesive tape layer is adhered to the two installation rollers respectively.

[0009] Preferably, the back surface of the support plate is symmetrically rotationally connected with a connecting disc, a first motor is fixed to one side of the support plate, the output of the first motor is fixedly connected with the center of one of the connecting discs, the back surface of the support plate is symmetrically provided with a connecting seat, the connecting seat is fixedly connected with a top rod on one side, one end of the top rod is fixedly connected with one side of the connecting seat, a spring is sleeved on the outer wall of the top rod, and the two ends of the spring are fixedly connected with the connecting seat and one side of the support plate respectively, and the other connecting disc is provided with a damper.

[0010] Preferably, the other end of the top rod is fixedly connected with a limiting block.

[0011] Preferably, a second motor is fixedly connected in the box, the output of the second motor is fixedly connected with a worm, one end of the support column away from the support plate is fixedly connected with a worm wheel, and the worm wheel is meshingly connected with the worm.

[0012] Preferably, one end of each of the two installation rollers is provided with a meshing groove, and one side of each of the two connecting discs is fixedly connected with a meshing strip.

[0013] Preferably, the support plate is rotated by 90 degrees and is located at the top of the ELISA kit.

[0014] Compared with the prior art, the utility model has the advantages that:

[0015] The reaction system is sealed, and the detection accuracy is ensured

[0016] The device drives the push plate to extrude the silica gel sealing gasket through the electric push rod, so that the silica gel layer is tightly attached to the top end of the ELISA kit, which can effectively prevent liquid evaporation in the reaction process and avoid the deviation of the detection result caused by the change of the sample concentration; the silica gel layer of the silica gel sealing gasket has good elasticity and sealing property, and cooperates with the pressure of the push plate, thereby solving the problems of poor adhesion of the manually covered sealing film and the sealing of the simple cover plate in the prior art, and significantly improving the sealing reliability of the reaction system, thereby providing a strong guarantee for the accuracy of the detection result;

[0017] Improve operation flexibility and efficiency to adapt to high-throughput detection requirements

[0018] With the transmission structure of the second motor, the worm and the worm gear, the support plate can be accurately rotated by 90 degrees to quickly displace the sealing component to the top end of the ELISA kit; the first motor drives the mounting roller to rotate, which can drive the silica gel sealing gasket to move to adjust the covering position, thereby meeting the sealing requirements of kits at different positions; without manually adjusting the position of the kit or replacing the sealing component, the problems of difficult sealing position adjustment and complicated operation in the prior art are solved, and the operation efficiency is greatly improved, which is especially suitable for high-throughput detection scenarios;

[0019] Convenient replacement of sealing components and reduced maintenance cost

[0020] The silica gel sealing gasket is connected to the mounting roller through the adhesive tape layer, and the mounting roller and the connecting disc are installed through the engagement strips and the engagement grooves, so that the mounting roller can be removed by pushing it along the axial direction and making the engagement strips and the engagement grooves disengage, and the mounting roller can be reset by reversing the operation after replacing the new silica gel sealing gasket; the structure design solves the problems of fixed connection and complex replacement of the sealing component in the prior art, simplifies the replacement process, reduces the maintenance time and cost, and facilitates the regular replacement of the sealing gasket to avoid cross contamination. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 It is a whole structure schematic view of the utility model;

[0022] Figure 2 It is a linear motor structure schematic view of the utility model;

[0023] Figure 3 It is a support plate whole structure schematic view of the utility model;

[0024] Figure 4 It is a push plate structure schematic view of the utility model;

[0025] Figure 5 It is an engagement groove structure schematic view of the utility model;

[0026] Figure 6 It is a top rod structure schematic view of the utility model;

[0027] Figure 7 The utility model discloses an installation roller structure schematic view.

[0028] In the drawing: 1, box body;2, linear motor;3, ELISA reagent kit;4, support plate;5, support column;6, silica gel sealing gasket;7, electric push rod;8, push plate;9, installation roller;10, limit block;31, connecting disc;32, first motor;33, connecting seat;34, jacking rod;35, spring;51, second motor;52, worm wheel;53, worm;61, meshing groove;62, meshing strip. DETAILED DESCRIPTION

[0029] The utility model discloses an installation roller structure schematic view.

[0030] Please refer to Figures 1-7 As shown in the drawing, an ELISA reagent kit reaction control device includes box body 1, support plate 4, electric push rod 7 and installation roller 9, the inside top fixedly connected with linear motor 2 at box body 1, the output end of linear motor 2 is fixedly connected with mechanical hand, the inside bottom installation has ELISA reagent kit 3 at box body 1, the inside rotationally connected with support column 5 at box body 1, the top fixedly connected with support plate 4 at support column 5, the one side installation of support plate 4 has silica gel sealing gasket 6, the inside fixedly connected with electric push rod 7 at support plate 4, the output end fixedly connected with push plate 8 at electric push rod 7, the one side contact silica gel sealing gasket 6 at push plate 8, the back surface symmetrical installation of support plate 4 has installation roller 9, two installation roller 9 are installed with silica gel sealing gasket 6 two ends cooperation respectively, silica gel sealing gasket 6 is divided into silica gel layer and adhesive tape layer, the silica gel layer is adhered on adhesive tape layer, the two ends of adhesive tape layer are adhered on two installation roller 9 respectively, after support plate 4 rotates 90 degrees, is located at the top of ELISA reagent kit 3;

[0031] The back surface rotationally connected with connecting disc 31 of support plate 4, the one side fixed with first motor 32 of support plate 4, the output end fixedly connected with one of connecting disc 31 centrum of first motor 32, the back surface symmetrical installation of support plate 4 has connecting seat 33, the one side fixedly connected with jacking rod 34 of connecting seat 33, the one end fixedly connected with connecting seat 33 of jacking rod 34 one side, the outer wall of jacking rod 34 is equipped with spring 35, and the two ends of spring 35 are fixedly connected with connecting seat 33 and the one side of support plate 4 respectively, the other end fixedly connected with limit block 10 of jacking rod 34, and the other connecting disc 31 is provided with damping;

[0032] The second motor 51 is fixedly connected in the box body 1, the output end of the second motor 51 is fixedly connected with a worm 53, the supporting column 5 is fixedly connected with a worm wheel 52 at the end away from the supporting plate 4, the worm wheel 52 is meshed with the worm 53;

[0033] One end of the two mounting rollers 9 is provided with a meshing groove 61, one side of the two connecting discs 31 is fixedly connected with a meshing strip 62, the meshing strip 62 is meshed with the meshing groove 61.

[0034] Working principle:

[0035] When the ELISA kit needs to be kept at a constant temperature, first, start the linear motor 2 at the top end in the box body 1, the linear motor 2 drives the mechanical hand connected with the output end to move away from the ELISA kit 3, so as to leave space for subsequent sealing operation; then, start the second motor 51 in the box body 1, the output end of the second motor 51 drives the worm 53 to rotate, since the worm 53 is meshed with the worm wheel 52 at the bottom end of the supporting column 5, the rotation of the worm 53 drives the worm wheel 52 to rotate, and then the supporting column 5 and the supporting plate 4 fixed at the top end thereof rotate synchronously; when the supporting plate 4 rotates 90 degrees, it is located at the top end of the ELISA kit 3, at this time, the silica gel sealing gasket 6 is opposite to the opening of the ELISA kit 3;

[0036] Then, start the electric push rod 7 in the supporting plate 4, the output end of the electric push rod 7 pushes the push plate 8 to move to one side of the silica gel sealing gasket 6, the push plate 8 applies pressure to the silica gel sealing gasket 6, so that the silica gel sealing gasket 6 tightly covers the ELISA kit 3, thereby avoiding liquid evaporation of the ELISA kit 3 during heating reaction;

[0037] When the silica gel sealing gasket 6 needs to be covered on different ELISA kits, start the first motor 32 on one side of the supporting plate 4, the output end of the first motor 32 drives the connecting disc 31 fixedly connected therewith to rotate, since the meshing strip 62 on the connecting disc 31 is meshed with the meshing groove 61 at one end of the mounting roller 9, the rotation of the connecting disc 31 drives the mounting roller 9 to rotate; the adhesive tape layer of the silica gel sealing gasket 6 is respectively adhered to the two mounting rollers 9, under the rotation of the mounting roller 9, the silica gel sealing gasket 6 moves, and the sealing position is adjusted; at the same time, the top rod 34 on the connecting seat 33 on the back of the supporting plate 4 is tightly connected with the connecting disc 31 under the elastic force of the spring 35, and the damping effect of the spring 35 is used, so that the silica gel sealing gasket 6 between the two mounting rollers 9 is always in a taut state, and the sealing effect is guaranteed;

[0038] When the silica gel sealing gasket 6 needs to be replaced, the mounting roller 9 is pushed along the axial direction of the mounting roller 9, the mounting roller 9 pushes the connecting disc 31, and then the top rod 34 on the connecting seat 33 compresses the spring 35, at this time, the engagement strip 62 is disengaged from the engagement groove 61, and the mounting roller 9 can be removed, and a new mounting roller 9 with a silica gel sealing gasket 6 is replaced; after the replacement is completed, the mounting roller 9 is loosened, the spring 35 returns to the original state, the top rod 34 pushes the connecting disc 31 to reset, and the engagement strip 62 is re-engaged with the engagement groove 61, and the fixing of the mounting roller 9 is completed.

[0039] During the whole process, the silica gel layer of the silica gel sealing gasket 6 can ensure good sealing performance, and the adhesive tape layer realizes stable connection with the mounting roller 9; the limiting block 10 at the other end of the top rod 34 can limit the movement range of the top rod 34, and ensure the stability of the structure; through the cooperative work of the above-mentioned components, effective control of the ELISA kit reaction process is realized.

[0040] It should be noted that, in this text, relational terms such as first and second and the like are used merely to distinguish one entity or action from another, without necessarily requiring or implying any such actual relationship or order between such entities or actions. Moreover, the terms "comprises", "comprising", or any other variations thereof, are intended to cover non-exclusive inclusions, so that a process, method, article, or apparatus that includes a list of elements does not only include those elements, but also includes other elements not explicitly listed, or other elements inherent to such a process, method, article, or apparatus.

[0041] Although the embodiments of the utility model have been shown and described, it can be understood by those of ordinary skill in the art that various changes, modifications, replacements and variations can be made to the embodiments without departing from the principles and spirits of the utility model, and the scope of the utility model is defined by the appended claims and their equivalents.

Claims

1. An ELISA kit reaction control device, characterized by, Include: Box (1), the top end of the box (1) is fixedly connected with a linear motor (2), the output end of the linear motor (2) is fixedly connected with a mechanical hand, the bottom end of the box (1) is installed with an ELISA kit (3); Supporting plate (4), the box (1) is rotatably connected with a supporting column (5), the top end of the supporting column (5) is fixedly connected with a supporting plate (4), one side of the supporting plate (4) is installed with a silica gel gasket (6); Electric push rod (7), the supporting plate (4) is fixedly connected with an electric push rod (7), the output end of the electric push rod (7) is fixedly connected with a push plate (8), one side of the push plate (8) contacts the silica gel gasket (6); The mounting roller (9) is installed on the back of the supporting plate (4) symmetrically, and the two mounting rollers (9) are installed with the silica gel gasket (6) at both ends.

2. The ELISA kit reaction control device according to claim 1, characterized in that: The silica gel gasket (6) is divided into a silica gel layer and a tape layer, the silica gel layer is adhered to the tape layer, and the two ends of the tape layer are adhered to the two mounting rollers (9) respectively.

3. The ELISA kit reaction control device according to claim 2, wherein: The back of the supporting plate (4) is rotatably connected with a connecting disc (31), one side of the supporting plate (4) is fixedly connected with a first motor (32), the output end of the first motor (32) is fixedly connected with one of the connecting discs (31), the back of the supporting plate (4) is symmetrically installed with a connecting seat (33), one side of the connecting seat (33) is fixedly connected with a top rod (34), one end of the top rod (34) is fixedly connected with one side of the connecting seat (33), the outer wall of the top rod (34) is sleeved with a spring (35), the two ends of the spring (35) are fixedly connected with the connecting seat (33) and one side of the supporting plate (4) respectively, and the other connecting disc (31) is provided with a damper.

4. The ELISA kit reaction control device according to claim 3, wherein: The other end of the top rod (34) is fixedly connected with a limiting block (10).

5. The ELISA kit reaction control device according to claim 1, wherein: The box (1) is fixedly connected with a second motor (51), the output end of the second motor (51) is fixedly connected with a worm (53), the end of the supporting column (5) away from the supporting plate (4) is fixedly connected with a worm wheel (52), and the worm wheel (52) is meshingly connected with the worm (53).

6. The ELISA kit reaction control device according to claim 3, wherein: One end of the two mounting rollers (9) is provided with a meshing groove (61), one side of the two connecting discs (31) is fixedly connected with a meshing strip (62), and the meshing strip (62) is meshingly connected with the meshing groove (61).

7. The ELISA kit reaction control device of claim 1, wherein: The supporting plate (4) is rotated by 90 degrees and is located at the top end of the ELISA kit (3).

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