Radiotherapy isolation device

Abstract

The utility model relates to a radiotherapy isolation device, which is mainly used for isolating normal tissues from tissues receiving radiotherapy, and comprises a plurality of isolation bags filled with hydrogel, the plurality of isolation bags are arranged in a multi-layer stacking mode to form the isolation device, the isolation bag comprises a skeleton isolation bag which is used as a structural support and is positioned on a middle layer, a surface layer isolation bag which is in direct contact with human tissues and covers the skeleton isolation bag, and a core isolation bag which is positioned in the skeleton isolation bag and is used for absorbing or isolating radiation. The core of the isolation device provided by the utility model is that the mechanical property of the formed whole device is adjusted by utilizing the change of the volume ratio of the isolation bag filled with the dry hydrogel. The isolation device provided by the utility model can solve the problems of deformation, displacement and poor radiation absorption effect at the same time.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, mainly to the field of tumor radiotherapy, and specifically to a radiotherapy isolation device. Background Technology

[0002] In tumor radiotherapy, ensuring therapeutic efficacy while minimizing damage to surrounding normal tissues is a complex and delicate process. Because radiation cannot completely distinguish between tumor cells and normal cells when treating tumors, effectively protecting nearby sensitive organs and tissues, especially those highly sensitive to radiation such as the intestines, glands, and lymph nodes, has become a key issue in radiotherapy.

[0003] To address this issue, the medical and engineering communities have developed various technologies and methods. One commonly used technique involves using tissue-equivalent materials as barriers. These materials can be custom-designed tissue compensators, tailored to mimic the density of human tissue to reduce radiation dose to normal tissues. For example, in radiotherapy for breast tumors, tissue-equivalent wedge-shaped fillers may be used to adjust the distribution of radiation, protecting the heart and lungs. In some cases, doctors may employ physical isolation techniques, such as in radiotherapy for prostate cancer, using hydrogels or other biomaterials as a barrier placed between the prostate and rectum to reduce the radiation dose to the rectum. For instance, SpaceOAR, developed by Boston Scientific, uses a special hydrogel to fill the space between the prostate and rectum to reduce radiation damage to the rectum, thereby lowering the risk of side effects such as radiation proctitis. However, this technique presents challenges due to individual differences in patient response and absorption.

[0004] Furthermore, CN107936272A discloses a sodium hyaluronate hydrogel 200 for tumor radiotherapy protection, which reduces the radiation dose received by the protected organ by increasing the distance between the radioactive ions and the protected organ. CN116440428A discloses an implantable tissue isolation device that can be repeatedly inflated and deflated in the body, comprising an isolation balloon, which is always placed between the normal tissue to be isolated and the radiotherapy-receiving tissue during a radiotherapy course; it is withdrawn from the body after the radiotherapy course; when the isolation balloon is placed in the body, it is used to isolate the normal tissue and the radiotherapy-receiving tissue after inflation; after being deflated, it is used to maintain the normal physiological state of the normal tissue and the radiotherapy-receiving tissue; the isolation balloon, when inflated, has two contact surfaces, namely a first contact surface and a second contact surface; the first contact surface contacts the normal tissue to be isolated, and the second contact surface contacts the radiotherapy-receiving tissue; the minimum distance between the first contact surface and the second contact surface is not less than the distance required for the radiation dose to decrease to a tolerable range for the normal tissue. Although the aforementioned products or technologies can be used to protect normal tissues or organs, they are mainly focused on the protection against prostate cancer, cervical cancer, etc. In the existing technology, there is no clear closed space to accommodate and shape isolation materials for many other types of tumors, especially those located in body cavities with relatively open surroundings.

[0005] In body cavities without clear boundaries, isolation materials are difficult to maintain their shape or position, and are therefore prone to displacement during human activity or changes in body position, even compressing human organs. For example, when isolating malignant tumors in the abdominopelvic cavity adjacent to the gastrointestinal tract (including pancreatic cancer, liver cancer, liver metastases, retroperitoneal soft tissue sarcoma, abdominopelvic recurrent tumors, advanced abdominal leiomyosarcoma, etc.), the tissues or organs receiving radiotherapy are relatively sensitive. If the isolation material shifts, it will compress the tumor tissue, thereby increasing the patient's discomfort.

[0006] Furthermore, on the one hand, there are differences in understanding among those skilled in the art; on the other hand, the applicant studied a large number of documents and patents when making this utility model, but due to space limitations, not all details and contents were listed in detail. However, this does not mean that this utility model does not have the features of these prior art. On the contrary, this utility model has all the features of the prior art, and the applicant reserves the right to add relevant prior art to the background art. Utility Model Content

[0007] To address the shortcomings of existing technologies, this utility model provides a radiotherapy isolation device, mainly used to isolate normal tissue from radiotherapy-receiving tissue. It includes several isolation bags filled with hydrogel, and the isolation bags are arranged in a multi-layer stacked manner to form the isolation device.

[0008] According to a preferred embodiment, the hydrogel is filled in different volume proportions in the isolation bag, thereby forming isolation bags with different mechanical properties.

[0009] According to a preferred embodiment, the isolation bag arranged in a multi-layered stacked manner to form an isolation device includes: a surface isolation bag that contacts human tissue; and a core isolation bag located in the inner layer of the surface isolation bag to absorb or isolate radiation.

[0010] According to a preferred embodiment, the filling volume of the hydrogel in the surface isolation bag is smaller than the filling volume of the hydrogel in the core isolation bag.

[0011] According to a preferred embodiment, the hydrogel in the surface isolation bag has a filling volume of 20% to 60%, preferably 20%.

[0012] According to a preferred embodiment, the hydrogel filling volume in the core isolation bag is 80% to 100%, preferably 80%.

[0013] According to a preferred embodiment, the multi-layer stacking method of the radiotherapy isolation device includes at least three layers of isolation bags.

[0014] According to a preferred embodiment, the radiotherapy isolation device has a core isolation bag as the central layer, and the surface isolation bags are wrapped from the central layer to the upper and lower layers respectively, thereby forming a sandwich structure isolation device.

[0015] According to a preferred embodiment, a surface isolation bag is draped over an outer contour frame to form a closed structure, and a core isolation bag is filled inside the closed structure, thereby forming a frame-type isolation device.

[0016] According to a preferred embodiment, the outer isolation bag is used to form a hemispherical outer shell spherical surface to adhere to normal tissue / or organs, and the core isolation bag is used to form a hemispherical base surface to absorb radiation, thereby forming a hemispherical isolation device.

[0017] According to a preferred embodiment, the radiotherapy isolation device is centered on a core isolation bag, with a surface isolation bag covering the outer layer from the center outwards, thereby forming a strip-shaped isolation device.

[0018] According to a preferred embodiment, the shape of the radiotherapy isolation device formed by the plurality of isolation bags can be sheet-like, frame-like, elliptical, hemispherical, strip-like, or a specific outline shape.

[0019] According to a preferred embodiment, the isolation bag arranged in a multi-layered stacked manner to form an isolation device further includes: a skeleton isolation bag in the middle layer as structural support.

[0020] According to a preferred embodiment, the filling volume of the hydrogel in the skeleton isolation bag is smaller than the filling volume of the hydrogel in the surface isolation bag.

[0021] According to a preferred embodiment, the filling volume of the hydrogel in the skeleton isolation bag is 5% to 10%, preferably 10%.

[0022] According to a preferred embodiment, the isolation bag filled with hydrogel is made of an absorbable polymer fiber membrane.

[0023] According to a preferred embodiment, a plurality of hydrogel-filled isolation bags can be assembled into a radiotherapy isolation device by means of adhesive bonding or sewing. Preferably, the plurality of hydrogel-filled isolation bags can be sequentially bonded together in a specific order using an adhesive.

[0024] According to a preferred embodiment, the hydrogel can be a dry hydrogel.

[0025] Technical Effects: The core of the isolation device provided by this invention lies in utilizing the change in the volume ratio of the isolation bags filled with dry hydrogel to adjust the mechanical properties of the overall device. This design aims to provide a more precise and personalized protection solution for tumor radiotherapy, minimizing radiation damage to surrounding normal tissues. The device consists of several isolation bags with different filling volumes. Dry hydrogel is a biocompatible material that, while maintaining its original mechanical properties, can adjust the overall stiffness and flexibility of the isolation bags according to the different filling volumes, thereby affecting its radiation absorption capacity.

[0026] In particular, the isolation device provided by this utility model can simultaneously solve the problems of deformation, displacement, and poor radiation absorption. The skeleton isolation bag has the smallest filling volume, high rigidity, is not easily deformed, and has good support characteristics; it is used to form the outer contour frame. The surface isolation bag has a larger filling volume than the skeleton isolation bag, and its rigidity is reduced, thus making it easier to integrate with human soft tissue and avoiding displacement due to mechanical mismatch between the isolation device and surrounding tissues. The core isolation bag has the largest filling volume, which can absorb as much radiation as possible, further reducing damage to normal tissues. Attached Figure Description

[0027] Figure 1 A schematic diagram of the sheet-like isolation device provided by this utility model;

[0028] Figure 2 A schematic diagram of the sheet-like isolation device provided by this utility model implanted between tumor tissue and normal tissue;

[0029] Figure 3 A schematic diagram of the disassembled frame-type isolation device provided by this utility model;

[0030] Figure 4 A schematic diagram of the assembled frame-type isolation device provided by this utility model;

[0031] Figure 5 A schematic diagram illustrating the application of the frame-type isolation device provided by this utility model;

[0032] Figure 6 A schematic diagram of the hemispherical isolation device provided by this utility model;

[0033] Figure 7 A schematic diagram of the disassembled hemispherical isolation device provided by this utility model;

[0034] Figure 8 A schematic diagram illustrating the application of the hemispherical isolation device provided by this utility model;

[0035] Figure 9 A schematic diagram of the strip-shaped isolation device provided by this utility model;

[0036] Figure 10 This is a schematic diagram illustrating the application of the strip-shaped isolation device provided by this utility model.

[0037] List of reference numerals

[0038] 100: Isolation bag; 110: Surface isolation bag; 120: Skeleton isolation bag; 130: Core isolation bag; 131: Cavity; 200: Hydrogel. Detailed Implementation

[0039] The following is a detailed description with reference to the accompanying drawings. In this invention, the isolation device is used to isolate tumor tissue from normal tissue, which is equivalent to isolating radiotherapy-receiving tissue from normal tissue.

[0040] In the description of this utility model, it should be noted that the terms "upper," "lower," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this utility model and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "provided with," "connected," etc., should be interpreted broadly. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be a connection within two components. "Several" means two or more, unless otherwise explicitly and specifically limited. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0041] Example 1

[0042] This embodiment provides a radiotherapy isolation device, which is mainly used to isolate normal tissue from radiotherapy-receiving tissue. After implantation into the human body, it functions to fix, support, expand, fill, and isolate body cavities and organs. The radiotherapy isolation device includes several isolation bags 100 filled with hydrogel 200. The hydrogel 200 is preferably a dry hydrogel 200. The preparation method of the dry hydrogel 200 is as follows: Select an appropriate hydrogel 200 material (such as polyethylene glycol, polyacrylic acid, polyvinyl alcohol, etc.), dissolve iohexol in an appropriate solvent (such as distilled water or physiological saline) to form a homogeneous solution (preferably a 10wt% iohexol solution), then introduce the iohexol solution into the hydrogel 200, and adjust the pH of the mixed solution to neutral or the desired pH range to promote the formation of the hydrogel 200. Allow the hydrogel 200 to solidify under certain conditions to form a stable three-dimensional network structure. Place the solidified hydrogel 200 in a freeze dryer for freeze-drying to remove moisture from the hydrogel 200. After freeze-drying, the dry hydrogel 200 is removed and finally ground into granular dry hydrogel 200 using a ball mill. In the preparation method of dry hydrogel 200, iohexol can be replaced with hydroxyapatite (HAP).

[0043] The isolation bag 100 filled with hydrogel 200 is made of an absorbable polymer fiber membrane. The isolation bag 100 made of the absorbable polymer fiber membrane can be composed of one or more of polyethylene glycol, hexafluoroisopropanol, polylactic acid, polydioxanone, polycaprolactone, polylactic acid-polyethylene glycol copolymer, and poly-L-lactic acid-ε-caprolactone. The preparation method of the absorbable polymer fiber membrane is as follows: Polylactic acid-polyethylene glycol copolymer (PLGA) is fully dissolved in HFIP to obtain a polymer solution. The concentration of the mixture solution is adjusted to a range suitable for electrospinning, typically between 5% and 30% (w / v), preferably prepared as a 15wt% polymer solution. The prepared polymer solution is loaded into a 10ml syringe, and an 18G needle is connected to the syringe. The absorbable polymer fiber membrane is then prepared by electrospinning. The positive and negative terminals of a high-voltage power supply are connected to the syringe needle and the receiving plate, respectively. The voltage is 15kV, the distance between the needle and the receiving plate is 20cm, and the flow rate of the polymer solution is 10μl / min. The polymer solution forms a jet under the influence of an electric field, which is ejected from the needle. As the jet travels towards the receiving plate, the solvent evaporates, and the polymer gradually solidifies into fibers. These fibers deposit on the receiver, forming a nonwoven fiber membrane. Electrospinning is performed in a fume hood (temperature 23±2℃, relative humidity 50%±1%), and the resulting fiber membrane is left overnight in the fume hood to remove residual solvents, ensuring complete evaporation of organic solvents from the fiber membrane. In the preparation method of the absorbable polymer fiber membrane, PLGA can be replaced with PLCL, while the remaining steps remain unchanged.

[0044] The radiotherapy isolation device can include at least three layers of isolation bags 100 filled with hydrogel 200. Several isolation bags 100 are arranged in a multi-layer stacked manner to form the isolation device. Several isolation bags 100 can be precisely cut and positioned, stacked in the order of inner layer, middle layer, and outer layer.

[0045] The isolation bag 100 includes a skeleton isolation bag 120, a surface isolation bag 110, and a core isolation bag 130. The skeleton isolation bag 120 is preferably located in the middle layer as a structural support. The surface isolation bag 110 is in direct contact with human tissue. The surface isolation bag 110 covers the skeleton isolation bag 120. The core isolation bag 130 is located inside the skeleton isolation bag 120. The core isolation bag 130 is primarily used to absorb or isolate radiation. The stacked isolation bags 100 are fixed with non-toxic adhesives or formed by sewing to ensure that displacement or delamination does not occur during use. The multi-layered stacking design ensures the stability and isolation effect of the isolation bag 100.

[0046] The filling volume of the hydrogel 200 in the skeleton isolation bag 120 is smaller than that in the surface isolation bag 110, and the filling volume of the hydrogel 200 in the surface isolation bag 110 is smaller than that in the core isolation bag 130. The filling volume of the hydrogel 200 in the skeleton isolation bag 120 is 5% to 10%, preferably 10%. The filling volume of the hydrogel 200 in the surface isolation bag 110 is 20% to 60%, preferably 20%. The filling volume of the hydrogel 200 in the core isolation bag 130 is 80% to 100%, preferably 80%. The multi-layer stacking of the radiotherapy isolation device includes at least three isolation bags 100. The radiotherapy isolation device can include five or more isolation bags 100, depending on the patient's individualized radiotherapy protection plan.

[0047] Example 2

[0048] This embodiment is a further improvement on embodiment 1, and repeated content will not be described again.

[0049] The isolation device consists of several isolation bags 100, with different types of isolation bags 100 having different volumes of hydrogel 200 filling. The isolation device preferably consists of five layers of isolation bags 100 to form a sandwich structure. A skeleton isolation bag 120 is preferably included between the core isolation bag 130 and the surface isolation bag 110. The central layer is the core isolation bag 130, the upper and lower surfaces of the core isolation bag 130 are configured as the skeleton isolation bag 120, and the outer surface of the skeleton isolation bag 120 is configured as the surface isolation bag 110. Figure 1As shown, the skeleton isolation bag 120 not only provides the necessary structural support for the entire isolation device, but also helps maintain the shape and position of the isolation bag 100, ensuring stability during radiotherapy. In practical applications, doctors can select the appropriate number and size of isolation bags 100 according to the location and size of the tumor, as well as the specific requirements of radiotherapy, to achieve the best isolation effect.

[0050] The isolation bag 100 is preferably designed as a sheet, filled with a specific volume of dry hydrogel 200, and the opening is sealed with an adhesive or sewn together using a biocompatible material. Several sheet-shaped isolation bags filled with dry hydrogel 200 are stacked and glued together to form an isolation device.

[0051] In use, the isolation device is precisely placed between the tumor tissue and normal tissue, such as... Figure 2 As shown. Due to its sandwich structure design, the isolation bag 100 in contact with human tissue is a soft and highly conforming surface isolation bag 110, while the core isolation bag 130, with a high filling rate of dry hydrogel 200, is capable of absorbing a large amount of radiation. Preferably, at the boundary of multiple stacked isolation bags 100, an isolation bag 100 with a filling volume of 10% to 20% of dry hydrogel 200 is used for boundary sealing. The filling volume of the boundary-sealed isolation bag 100 is, for example, 15%. The strength of the boundary-sealed isolation bag 100 is between that of the surface isolation bag 110 and the skeleton isolation bag 120, which can maintain the original shape and avoid damage to organs or tissues at the boundary. The isolation device can significantly reduce the radiation dose received by normal tissues without affecting the treatment effect. At the same time, because the surface isolation bag 110 of the isolation device conforms well to human tissue, the isolation device is not easily displaced even with changes in body position or other activities.

[0052] This isolation device can be used for tumors in the skin or superficial tissues, such as basal cell carcinoma or squamous cell carcinoma. When the tumor is located in a body cavity and close to the surface, the sheet-like isolation device can be implanted between the tumor and normal tissue (e.g., laid flat around the tumor), a design that helps reduce radiation exposure to surrounding organs.

[0053] In addition, the sheet-like isolation device can also be used for protection after tumor resection. That is, after tumor resection, the sheet-like isolation bag 100 can be used to protect the surgical area and prevent damage to normal tissues during radiotherapy. If the patient has multiple small tumor nodules, the sheet-like isolation bag 100 can be used in multiple areas simultaneously to isolate each tumor one by one and reduce radiation to normal tissues.

[0054] Example 3

[0055] This embodiment is a further improvement on embodiment 1, and repeated content will not be described again.

[0056] The radiotherapy isolation device in this embodiment adopts a frame structure design, specifically a square frame, such as... Figure 3 and Figure 4 As shown. The skeleton isolation bag 120 forms the framework of the isolation device, possessing high rigidity and resistance to deformation. The skeleton isolation bag 120 provides necessary mechanical support. The skeleton isolation bag 120 also mimics the outer contour of the human anatomical structure, ensuring the overall isolation device conforms to the shape of normal tissue. The surface isolation bag 110 covers the skeleton isolation bag 120, forming a closed structure. The design of the surface isolation bag 110 ensures the overall airtightness of the isolation device, providing both an additional protective layer and a tissue-fitting layer, avoiding discomfort to the patient. The skeleton isolation bag 120 is preferably configured as a frame to protect the outer contour of normal tissue. The core isolation bag 130 is located within the closed structure formed by the skeleton isolation bag 120 and the surface isolation bag 110. The core isolation bag 130 effectively absorbs and scatters radiation, reducing radiation damage to normal tissue. The design of the core isolation bag 130 allows it to expand freely within the closed structure to adapt to the needs of different patients and treatment sites. The isolation device provided in this embodiment can be used in the treatment of abdominal tumors, protecting surrounding tissues such as the intestines, bladder, and uterus. For tumors located within the abdominal cavity, such as pancreatic cancer or ovarian cancer, the square-framed isolation device can help stabilize the tumor's position. Figure 5 As shown, the frame device provides additional protection against radiation damage to normal tissues. In tumors near the spine, such as spinal metastases, the frame device stabilizes the tumor and provides effective isolation to protect neural structures. In the treatment of liver cancer, the isolation device helps protect normal liver tissue and other abdominal organs (such as the stomach and kidneys).

[0057] Example 4

[0058] This embodiment is a further improvement on embodiment 1, and repeated content will not be described again.

[0059] This embodiment provides a hemispherical radiotherapy isolation device. Specifically, the outer isolation bag 110 is designed as a hemispherical outer shell, such as... Figure 6 As shown, its purpose is to closely adhere to and cover the surface of normal tissue or organs. This design allows the isolation bag 100 to precisely match the contours of the human body surface. The core isolation bag 130 forms a hemispherical base, located below the outer isolation bag 110, directly facing the radiation source. The base formed by the core isolation bag 130 preferably has a cavity 131 for accommodating organs. The cavity 131 can be located in the center of the base, such as... Figure 7As shown. The hydrogel 200 filled within the core isolation bag 130 effectively absorbs and isolates radiation, protecting normal tissue from radiation damage. The skeleton isolation bag 120, located between the surface isolation bag 110 and the core isolation bag 130, serves as structural support and connection. The hemispherical shell and the base surface are interlocked by the skeleton isolation bag 120, ensuring a tight fit and stability between the layers. This structure not only enhances the overall mechanical strength of the device but also helps maintain the shape and position of the isolation bags 100, preventing displacement during treatment. The arrangement and design of the isolation bags 100 form a complete hemispherical structure, providing all-around radiation isolation. The hemispherical design of the surface isolation bag 110 and the core isolation bag 130 allows the device to adapt to different anatomical curves, while the skeleton isolation bag 120 ensures structural integrity and stability. For example, when a tumor is located at the apex of the lung (lung tumor) or near the heart, a hemispherical isolation device can surround the tumor, such as... Figure 8 As shown, the surface isolation bag 110 is in contact with and adheres to the surrounding normal tissue, and the isolation device ensures effective isolation between the tumor tissue and normal tissue. When radiotherapy is performed, after the radiation reaches the tumor tissue, it mainly acts on the tumor tissue. Because the basal surface absorbs as much radiation as possible, the damage to normal tissue is minimized.

[0060] Example 5

[0061] This embodiment is a further improvement on embodiment 1, and repeated content will not be described again.

[0062] This embodiment provides a strip-shaped radiotherapy isolation device. Specifically, the isolation device has a core isolation bag 130 as its center, and forms a strip-shaped structure by successively covering the skeleton isolation bag 120 and the surface isolation bag 110, as shown below. Figure 9 As shown. The core isolation bag 130, as the core of the isolation device, is designed to play a crucial role. Located at the heart of the device, it is protected by the skeleton isolation bag 120 and the outer isolation bag 110, maintaining its function of maximizing radiation absorption over a long period. The skeleton isolation bag 120 surrounds the core isolation bag 130, providing necessary structural support and shape maintenance. The design of the skeleton isolation bag 120 allows it to provide additional mechanical strength and stability while maintaining the shape of the core isolation bag 130. The outer isolation bag 110 covers the outside of the skeleton isolation bag 120 and comes into direct contact with the patient's skin. The outer isolation bag 110 prioritizes comfort, reducing patient discomfort.

[0063] The isolation bags 100 are arranged in a strip-like structure, which can be customized according to the specific shape and size of the treatment area. The multi-layered design, from the core isolation bag 130 to the outer isolation bag 110, not only enhances the overall performance of the isolation device but also improves its ability to absorb and scatter radiation. Each layer of isolation bag 100 plays a different role, collectively forming a highly efficient isolation system. For brain tumors, this isolation device can be used to protect brain tissue and important neural structures. In the treatment of spinal tumors, this isolation device can be used to protect the spinal cord and other sensitive neural structures, such as… Figure 10 As shown. For tumors in the limbs, this isolation device can be used to protect the surrounding muscles, nerves, and blood vessels.

[0064] It should be noted that the above specific embodiments are exemplary. Those skilled in the art can devise various solutions inspired by the disclosure of this utility model, and these solutions all fall within the scope of this utility model and its protection scope. Those skilled in the art should understand that this utility model specification and its drawings are illustrative and do not constitute a limitation on the claims. The protection scope of this utility model is defined by the claims and their equivalents. This utility model specification contains multiple inventive concepts; phrases such as "preferredly" and "according to a preferred embodiment" indicate that the corresponding paragraph discloses an independent concept. The applicant reserves the right to file divisional applications based on each inventive concept. Throughout the text, the feature introduced by "preferredly" is only an optional mode and should not be construed as mandatory. Therefore, the applicant reserves the right to abandon or delete relevant preferred features at any time.

Claims

1. A radiotherapy isolation device, characterized in that, The radiation therapy isolation device comprises a plurality of isolation bags (100) filled with hydrogel (200), and the plurality of isolation bags (100) are arranged in a multi-layer stack to form the isolation device.

2. The radiotherapy isolation device of claim 1, wherein, The volume of the hydrogel (200) filled in the isolation bag (100) is different, so as to form isolation bags (100) with different mechanical properties.

3. The radiotherapy isolation device of claim 1 or 2, wherein, The isolation bags (100) arranged in a multi-layer stack to form the isolation device comprise: a surface layer isolation bag (110) in contact with human tissue; and a core isolation bag (130) for absorbing or isolating radiation located in the inner layer of the surface layer isolation bag (110).

4. The radiotherapy isolation device of claim 1, wherein, The filling volume of the hydrogel (200) in the surface layer isolation bag (110) is less than that in the core isolation bag (130).

5. The radiotherapy isolation device of claim 1, wherein, The filling volume of the hydrogel (200) in the surface layer isolation bag (110) is 20% to 60%. And / or the filling volume of the hydrogel (200) in the core isolation bag (130) is 80% to 100%.

6. The radiotherapy isolation device of claim 1, wherein, The radiation therapy isolation device takes the core isolation bag (130) as the center layer, and includes surface layer isolation bags (110) above and below the center layer, respectively, to form a sandwich structure isolation device.

7. The radiotherapy isolation device of claim 1, wherein, The surface layer isolation bag (110) is coated on the outer contour frame to form a closed structure, and the core isolation bag (130) is filled in the inside of the closed structure, so as to form a frame type isolation device.

8. The radiotherapy isolation device of claim 1, wherein, The surface layer isolation bag (110) is used to form a hemispherical shell surface to adhere to normal tissue and / or organs, and the core isolation bag (130) is used to form a hemispherical base surface to absorb radiation, so as to form a hemispherical isolation device.

9. The radiotherapy isolation device of claim 1, wherein, The radiation therapy isolation device takes the core isolation bag (130) as the center, and the surface layer isolation bag (110) is coated outside the center, so as to form a strip-shaped isolation device.

10. The radiotherapy isolation apparatus as claimed in any one of claims 1 to 9, wherein, The isolation bags (100) arranged in a multi-layer stack to form the isolation device further comprise: a skeleton isolation bag (120) in the middle layer as a structural support.

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