Device for improving intraoperative cornea drug concentration

Abstract

The utility model discloses a device for improving intraoperative cornea drug concentration, which comprises a dome-shaped cover body, a micro-needle array is formed on the inner surface of the cover body, and a handle is detachably arranged on the outer surface of the cover body; the microneedle array is composed of a plurality of microneedles, each microneedle is of a two-layer structure, the outer layer is of a porous structure, and the inner layer is made of a material with a drug sustained release function. When in use, the micro-needle device is pressed on the cornea, and the micro-needle array penetrates through the surface layer of the cornea to form a plurality of micropores, so that the medicine can smoothly penetrate through the cornea, the micro-needle device can also be used before an operation, and the medicine concentration in the cornea can meet the concentration requirement in the predicted operation time by utilizing the slow release of the medicine in the micro-needles.

Description

TECHNICAL FIELD

[0001] The utility model relates to ophthalmic operation auxiliary equipment field, especially in improving the device of intraoperative corneal drug concentration. BACKGROUND

[0002] Corneal crosslinking operation needs to use drugs such as riboflavin to whole cornea in operation, and needs to keep predetermined concentration in a certain time, and the existing method is to drop drug, but cornea is smooth and is located at eyeball high point, and drug retention time is short, so a device can be targeted to improve the concentration of cornea inside. UTILITY MODEL CONTENT

[0003] The utility model discloses at least one of the above-mentioned technical problems in the technical field is solved to some extent.The utility model provides a device for improving the drug concentration of corneal area in a short time.

[0004] To achieve the above object, the embodiment of the utility model provides a device for improving the drug concentration of corneal in operation, comprising:

[0005] Cover body: vault, the inner surface forms microneedle array, and the outer surface is detachably provided with handle;

[0006] Microneedle array: by several microneedles, and the microneedle is two-layer structure: wherein the outer layer is porous structure, and the inner layer is the material with drug slow-release function.

[0007] According to the device for improving the drug concentration of corneal in operation of the utility model embodiment, use is pressed on cornea, and a plurality of micropores are formed by microneedle array penetrating corneal surface layer, so that drug can smoothly penetrate cornea, and the device can also be used before operation, and the drug concentration in cornea reaches concentration requirement in the expected operation time by using drug slow-release in microneedle.

[0008] In addition, the device for improving the drug concentration of corneal in operation according to the above embodiment of the utility model can also have the following additional technical features:

[0009] Optionally, the cover body forms a break to the top and down.

[0010] Optionally, the inner layer of the microneedle is PLGA material.

[0011] Optionally, the intersection point of the microneedle array points to the center of the circle corresponding to the curvature of the anterior surface of the cornea.

[0012] Optionally, the microneedle array is vertically directed to the iris.

[0013] Optionally, the microneedle array is spirally arranged along the inner surface of the cover body.

[0014] Optionally, the inner surface of the cover body forms a groove in the area between the microneedles.

[0015] Further, the grooves are interconnected with each other. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 is a perspective view according to one embodiment of the present application;

[0017] Figure 2 is a perspective view according to another embodiment of the present application;

[0018] Figure 3 is Figure 2 a top view of the embodiment;

[0019] Figure 4 is a sectional view according to one embodiment of the present application;

[0020] Figure 5 is a sectional view according to another embodiment of the present application;

[0021] Figure 6 is a partial structure enlarged view according to one embodiment of the present application.

[0022] REFERENCE NUMERALS:

[0023] cover 1 handle 11 fracture 12 groove 13

[0024] microneedle array 2 microneedle 21. DETAILED DESCRIPTION

[0025] Embodiments of the present application will be described in detail below, examples of which are shown in the drawings, wherein the same or similar reference numerals represent the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary and are intended to explain the present application, and should not be understood as a limitation of the present application.

[0026] The present application is used in a manner similar to a contact lens on the cornea, and the cover is hollow to avoid blocking the pupil and affecting vision, and the microneedles can slowly release the drug to the subepithelial tissue of the cornea.

[0027] In order to better understand the above technical solutions, the exemplary embodiments of the present application will be described in more detail below with reference to the drawings. Although the exemplary embodiments of the present application are shown in the drawings, it should be understood that the present application can be implemented in various forms and should not be limited by the embodiments described herein. On the contrary, these embodiments are provided to enable a more thorough understanding of the present application and to fully convey the scope of the present application to those skilled in the art.

[0028] For better understanding of the above technical solutions, the above technical solutions will be described in detail below in combination with the drawings and specific embodiments of the specification.

[0029] Figures 1 to 6 For a device for improving intraoperative corneal drug concentration according to the embodiment of the utility model, comprising: cover body 1: dome, the inner surface forms microneedle array 2, the outer surface is equipped with handle 11, handle 11 is convenient for surgeon to hold when using, and it is convenient to apply pressure, combine it with cornea, handle 11 can be detachably combined with cover body 1, after disassembly, handle part is removed, and a convex part is left standing in cover body 1, which is convenient to take down after use;Microneedle array 2: it is composed of several microneedles 21, microneedle 21 is two-layer structure: wherein the outer layer is porous structure, and the inner layer is material with drug release function.

[0030] Specifically, the inner layer is a PLGA material, which can pre-load the drug into the material during the microneedle 21 forming process, so that the drug is encapsulated in the inner layer of the microneedle 21. When used, the porous structure of the outer layer of the microneedle 21 allows the drug to be slowly released into the cornea. This solution also makes the device more versatile: it can be used before surgery, allowing the drug to reach a peak in a smooth process to reduce irritation.

[0031] Microneedle array 2 can be combined in the following way, alone or in combination: the intersection of microneedle array 2 points to the inside of the eyeball. This structure, when used, is equivalent to a claw gripping the corneal surface, reducing shedding.

[0032] In some embodiments, microneedle array 2 points vertically to the iris. Compared with the above-mentioned scheme, this scheme is more convenient to take down after use.

[0033] The above two ways can also be combined.

[0034] Microneedle array 2 is arranged along the inner surface in a spiral manner. Here, the spiral manner refers to spreading in a spiral manner around an axis pointing from the top surface of the dome to the bottom surface. The purpose of this structure is also to better adhere to the corneal surface.

[0035] Optionally, the inner surface of cover body 1 forms a groove 13 in the area between microneedles 21. This groove 13 can store some liquid. When using the embodiment of the utility model, if eye drops are also used, the groove 13 can keep the eye drops in it, prolonging the action time of the eye drops.

[0036] Further, the grooves 13 are interconnected, which can further expand the volume of the grooves 13.

[0037] In order to better adapt to different eyeball surfaces, the cover body 1 is formed with a break 12 from top to bottom, so that the cover body 1 can be deformed to a certain extent, and the application range is wider.

[0038] In the embodiment of the utility model, press in cornea during use, form a plurality of micro -holes through micro -needle array penetration corneal surface layer, make medicine can penetrate cornea smoothly, also can use before operation, utilize the medicine slow release in micro -needle makes the medicine concentration in cornea reach concentration requirement when expected operation time.

[0039] The outer layer of the microneedle 21 is made of a porous material, and the inner layer is made of a slow-release material, so as to realize slow-release drug delivery on the cornea.

[0040] According to the anatomical characteristics of the cornea, the length and diameter of the microneedle 21 can be designed in different sizes as needed to ensure safety and comfort during use.

[0041] In the description of the utility model, it is understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise" and the like indicate the orientation or positional relationship shown in the drawings, and are only used to facilitate the description of the utility model and simplify the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the utility model.

[0042] In the utility model, unless otherwise expressly specified and limited, the first feature is "on" or "below" the second feature, which can include direct contact between the first and second features, or indirect contact between the first and second features through another feature therebetween. Moreover, the first feature "above", "above" and "above" the second feature includes the first feature directly above and obliquely above the second feature, or only indicates that the horizontal height of the first feature is higher than that of the second feature. The first feature "below", "below" and "below" the second feature includes the first feature directly below and obliquely below the second feature, or only indicates that the horizontal height of the first feature is less than that of the second feature.

[0043] In the description of the present specification, the description referring to the terms "one embodiment", "some embodiments", "an example", "a specific example", or "some examples" and the like means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present application. In the present specification, the illustrative description of the above terms should not be understood as necessarily referring to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art can combine and integrate different embodiments or examples described in the present specification.

[0044] Although the embodiments of the present application have been shown and described above, it should be understood that the above-described embodiments are exemplary and should not be construed as limiting the present application, and those skilled in the art can make changes, modifications, replacements and variations to the above-described embodiments within the scope of the present application.

Claims

1. A device for increasing intraoperative corneal drug concentration, characterized by: The device comprises The cover: dome-shaped, the inner surface forms a microneedle array, the outer surface is detachably provided with a handle; The microneedle array: composed of a plurality of microneedles, the microneedle is a two-layer structure: the outer layer is a porous structure, and the inner layer is a material with drug release function.

2. The device for improving the drug concentration of the cornea during surgery according to claim 1, wherein: The cover is formed with a fracture from top to bottom.

3. The device for improving the drug concentration of the cornea during surgery according to claim 1, wherein: The inner layer of the microneedle is PLGA material.

4. The device for improving the drug concentration of the cornea during surgery according to any one of claims 1 or 2, wherein: The intersection of the microneedle array points to the center of the corneal anterior surface curvature.

5. The device for improving the drug concentration of the cornea during surgery according to any one of claims 1 or 2, wherein: The microneedle array is perpendicular to the iris.

6. The device for improving the drug concentration of the cornea during surgery according to any one of claims 1 or 2, wherein: The microneedle array is spirally arranged along the inner surface of the cover.

7. A device for increasing intraoperative corneal drug concentration as claimed in any one of claims 1 or 2, wherein: The inner surface of the cover, the area between the microneedles forms a groove.

8. The device for improving the drug concentration of the cornea during surgery according to claim 7, wherein: The grooves are crosslinked with each other.

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