High-purity ritonavir refining equipment

Abstract

The utility model discloses high-purity ritonavir refining equipment, which belongs to the technical field of chemical equipment and comprises a carrier unit, a primary filtering unit and a fine filtering unit, the primary filtering unit comprises a liquid guide cylinder fixedly mounted on the upper surface of a top plate, a positioning groove is formed in the top of the liquid guide cylinder, a lantern ring is inserted into the positioning groove, and the lantern ring is inserted into the liquid guide cylinder. A connecting block is fixedly installed on the inner wall of the lantern ring and fixedly connected with a filtering mechanism located in the liquid guiding cylinder, a guide plate which is obliquely installed under the discharging opening is fixedly installed at the bottom of the connecting column, one side of the guide plate is provided with an opening, and a first filtering net is placed on the upper surface of the guide plate; a guide plate is arranged on one side of the top plate, a discharging plate which is obliquely connected with the top plate through a fixing column is arranged below the guide plate, a second filter screen is arranged on the upper surface of the discharging plate, and a screen opening is formed in one side of the discharging plate.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of chemical equipment, specifically is a high -purity ritonavir refining equipment. BACKGROUND

[0002] Ritonavir, western medicine name, commonly used agent has tablet, capsule, oral solution agent etc., is antiviral drug, alone or with the nucleoside drug of antiretroviral drug is used to treat advanced or non -progressive AIDS patient, is the first -line treatment drug of AIDS, therefore, if the drug adulteration too much impurity also can directly influence the use effect of drug, thereby further influence the development of illness.

[0003] When processing ritonavir, the impurities in the drug solution affect the overall purity, and if purification is needed, the impurities in the ritonavir drug solution need to be fully removed.

[0004] The existing refining equipment is usually single impurity removal filtration, and the impurity removal effect is poor, which often causes too many impurities to remain after impurity removal, affecting the quality of the drug.

[0005] Therefore, it is necessary to provide a better impurity removal filtration, improve the impurity removal effect, and reduce the influence on the quality of the drug. UTILITY MODEL CONTENTS

[0006] The utility model discloses a high -purity ritonavir refining equipment to at least one degree to solve the above -mentioned technical problem, to better for the drug solution carries out the impurity removal filtration.

[0007] To achieve the above object, the utility model provides the following technical scheme: including carrier unit, primary filter unit and fine filter unit, the carrier unit includes jar body, the fine -mouth filter screen that sets up in the jar body, the top plate that is in the fine -mouth filter screen top and the jar body is connected, the discharge pipe that is installed with the jar body bottom is inclined;

[0008] The primary filter unit includes the liquid guide cylinder fixedly installed on the top surface of the top plate, the top of the liquid guide cylinder is equipped with the positioning groove, the positioning groove is inserted into the sleeve ring, the inner wall of the sleeve ring is fixedly installed with the connecting block and is fixedly connected with the filter mechanism in the liquid guide cylinder, the outer wall of the sleeve ring is fixedly installed with the connecting rod, the end of the connecting rod away from the sleeve ring is fixedly installed with the limiting block, the support block is vertically installed on the top plate, the support block is equipped with the electric cylinder towards the liquid guide cylinder direction, the electric cylinder is connected with the traction rope on the extension end, the other end of the traction rope is connected with the connecting rod;

[0009] The fine filter unit comprises a discharge port passing through the top plate and the liquid guide cylinder, a connecting column fixedly connected with the bottom of the top plate, a guide plate fixedly installed at the bottom of the connecting column and obliquely installed right below the discharge port, an open side of the guide plate, a first filter screen placed on the upper surface of the guide plate, a discharge plate obliquely passing through a fixed column and connected with the top plate below the guide plate, a second filter screen arranged on the upper surface of the discharge plate, and a mesh opening arranged on one side of the discharge plate.

[0010] Preferably, the tank body is hollow, the small-mouth filter screen is placed above the fixed block fixedly installed on the inner wall of the tank body, and the upper surface area of the small-mouth filter screen is greater than the upper surface area of the fine filter unit.

[0011] Preferably, the extension end of the electric cylinder is not in contact with the liquid guide cylinder, and the bottom of the filter mechanism is provided with a small-mouth filter screen.

[0012] Preferably, the discharge port is right above the first filter screen, and the lower surface area of the discharge port is smaller than the lower surface area of the first filter screen.

[0013] Preferably, the first filter screen is placed inside the guide plate, and the first filter screen is blocked by the connecting column installed on the guide plate.

[0014] Preferably, the discharge plate is below the guide plate, and the upper surface area of the discharge plate is greater than the upper surface area of the guide plate.

[0015] Preferably, the upwardly inclined section of the second filter screen is obliquely arranged, the middle section of the second filter screen is parallelly arranged, the downwardly inclined section of the second filter screen is planarly arranged, and the downwardly inclined section of the discharge plate is meshingly arranged.

[0016] Compared with the prior art, the fine filter unit has the following beneficial effects:

[0017] 1. The utility model discloses a sleeve ring is inserted in the positioning groove when using, make the filtering mechanism be in the inside of the liquid guide cylinder, then the medicinal liquid is poured into the filtering mechanism and carries out the preliminary filtration, the traction rope is connected with the connecting rod and drives the sleeve ring to rotate in the positioning groove through the extension end of electric cylinder extension and pull, the medicinal liquid that the filtering mechanism can be shaken to some extent with the liquid flows down that accumulates in the filtering mechanism is prevented by the impurity that the medicinal liquid is intercepted, the medicinal liquid flows to the first filter screen on the guide plate through the discharge port, and the impurity in the medicinal liquid is intercepted by the first filter screen, and the medicinal liquid continues to flow from below the first filter screen and falls to the discharge plate, because the second filter screen is inclined and is arranged, make the medicinal liquid move to the above-mentioned second filter screen and carry on the filtration of the impurity and continue to move, and the medicinal liquid is further intercepted and filtered and flows to the small -bore filter screen in the small -bore filter screen mouth segment and is further intercepted and filtered, and finally the medicinal liquid is discharged through the discharge pipe, effectively intercepts the impurity in the medicinal liquid, reduces the impurity residue, prevents the influence drug quality.

[0018] 2. The utility model discloses a filtering part, filtering mechanism, first filter screen, second filter screen and small -bore filter screen can carry out dismouting operation when using, convenient to the cleaning of filtering part, prevent the impurity accumulation, effectively keep each time filtration interception operation is effective, and greatly improve the purity of refining. ACCURACY

[0019] In order to more clearly illustrate the technical scheme of the embodiment of the utility model, the following will be to the embodiment description needed to use the drawing briefly introduced, obviously, the following description in the drawing is only some embodiments of the utility model, for the ordinary skilled person in the art comes, under the premise of not paying the creative labor, can also obtain other drawings according to these drawings.

[0020] Figure 1 It is the overhead view schematic diagram of the whole structure of this embodiment;

[0021] Figure 2 It is the enlarged schematic diagram of structure A of this embodiment;

[0022] Figure 3 It is the overhead view schematic diagram of the whole structure of this embodiment;

[0023] Figure 4 It is the inside structure schematic diagram of the carrier unit of this embodiment.

[0024] In the drawing, the component list that each sign represents is as follows:

[0025] 100, carrier unit;110, tank body;120, small -bore filter screen;130, top plate;140, discharge pipe;

[0026] 200, primary filter unit; 210, liquid guide cylinder; 211, positioning groove; 220, collar; 221, connecting block; 230, filtering mechanism; 240, connecting rod; 241, limiting block; 250, supporting block; 260, electric cylinder; 261, traction rope;

[0027] 300, fine filter unit; 310, discharge port; 320, connecting column; 330, guide plate; 331, first filter screen; 340, fixing column; 350, discharge plate; 351, second filter screen. DETAILED DESCRIPTION

[0028] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.

[0029] Please refer to Figures 1-4 The utility model provides a kind of technical scheme: a high-purity ritonavir refining equipment, including carrier unit 100, primary filter unit 200 and fine filter unit 300, carrier unit 100 includes jar body 110, narrow mouth filter screen 120 being arranged in jar body 110, jar body 110 is hollowly arranged, narrow mouth filter screen 120 is placed on the fixed block fixedly installed on the inner wall of jar body 110 above.

[0030] Jar body 110 can keep the drug liquid into it and flow normally, and the drug liquid filtered and intercepted by narrow mouth filter screen 120 can be filtered and intercepted again, and after multiple filtering operations, the impurities in the drug liquid can be better intercepted and removed, narrow mouth filter screen 120 is supported by fixed block in jar body 110, which facilitates disassembly, cleaning or replacement of narrow mouth filter screen 120, and is prevented from falling off by fixed block support.

[0031] The upper surface area of narrow mouth filter screen 120 is greater than the upper surface area of fine filter unit 300, top plate 130 connected with jar body 110 above narrow mouth filter screen 120, and discharge pipe 140 is installed inclinedly with the bottom of jar body 110.

[0032] Narrow mouth filter screen 120 is the last component for filtering drug liquid, which can ensure that the drug liquid filtered by fine filter unit 300 is received, and can support primary filter unit 200 through top plate 130, and can perform first filtering operation on drug liquid above carrier unit 100, and the filtered drug liquid can flow out of collection through discharge pipe 140.

[0033] Please refer to Figure 2In a preferred embodiment, the primary filtering unit 200 comprises a liquid guide cylinder 210 fixedly installed on the upper surface of the top plate 130, the top of the liquid guide cylinder 210 is provided with a positioning groove 211, the positioning groove 211 is inserted with a sleeve ring 220, the inner wall of the sleeve ring 220 is fixedly installed with a connecting block 221, and the connecting block 221 is fixedly connected with a filtering mechanism 230 inside the liquid guide cylinder 210.

[0034] The liquid guide cylinder 210 can keep the medicinal liquid only move downward along it and be discharged through the discharge port 310 at the bottom. The positioning groove 211 is arranged to enable the sleeve ring 220 to be inserted and rotated therein, and the sleeve ring 220 can keep the filtering mechanism 230 connected therewith in the liquid guide cylinder 210 to stably perform the filtering work and facilitate the disassembly and assembly of the sleeve ring 220 and the filtering mechanism 230 for cleaning work.

[0035] Referring to Figure 1 and Figure 2 In a preferred embodiment, the outer wall of the sleeve ring 220 is fixedly installed with a connecting rod 240, the end of the connecting rod 240 away from the sleeve ring 220 is fixedly installed with a limiting block 241, the upper portion of the top plate 130 is vertically installed with a supporting block 250, the supporting block 250 is provided with an electric cylinder 260 towards the liquid guide cylinder 210, the extending end of the electric cylinder 260 is connected with a traction rope 261, the other end of the traction rope 261 is connected with the connecting rod 240, and the extending end of the electric cylinder 260 is not in contact with the liquid guide cylinder 210.

[0036] The two ends of the traction rope 261 are respectively connected with the extending end of the electric cylinder 260 and the connecting rod 240, the limiting block 241 can prevent the traction rope 261 on the connecting rod 240 from falling off, and the extending end of the electric cylinder 260 can drive the sleeve ring 220 to rotate in the positioning groove 211 when the extending end of the electric cylinder 260 extends and retracts, which can rotate the filtering mechanism 230 to a certain extent, shake the medicinal liquid in the filtering mechanism 230, prevent impurities from blocking the downward movement of the medicinal liquid, and enable the electric cylinder 260 to sufficiently extend and retract without being blocked by the liquid guide cylinder 210.

[0037] The bottom of the filtering mechanism 230 is provided with a fine mesh filter, which can effectively prevent impurities from moving downward with the medicinal liquid.

[0038] Referring to Figure 3 , Figure 4 In a further preferred embodiment, the fine filtering unit 300 comprises a discharge port 310 passing through the top plate 130 and the liquid guide cylinder 210, the discharge port 310 is directly above a first filter screen 331, and the lower surface area of the discharge port 310 is smaller than that of the first filter screen 331.

[0039] The liquid guide cylinder 210 can flow downward through the discharge port 310 to the first filter screen 331 for interception and filtration, and the first filter screen 331 can certainly receive the downwardly discharged liquid medicine at the discharge port 310 to fully filter the liquid medicine.

[0040] The connecting column 320 fixedly connected to the bottom of the top plate 130 is fixedly installed at the bottom of the connecting column 320, and the guide plate 330 is obliquely installed below the discharge port 310. One side of the guide plate 330 is provided with an opening, and the first filter screen 331 is placed on the upper surface of the guide plate 330. The first filter screen 331 is placed inside the guide plate 330, and the first filter screen 331 is blocked by the connecting column 320 installed on the guide plate 330.

[0041] The oblique arrangement of the guide plate 330 can continue to flow the filtered liquid medicine for subsequent filtration processing, prevent the accumulation of liquid medicine, and the first filter screen 331 is directly placed on the guide plate 330, which is blocked by the connecting column 320, facilitating the disassembly, cleaning and other operations of the first filter screen 331.

[0042] The lower side of the guide plate 330 is provided with a discharge plate 350 obliquely connected to the top plate 130 through a fixed column 340, and the upper surface of the discharge plate 350 is provided with a second filter screen 351. The discharge plate 350 is below the guide plate 330, and the upper surface of the discharge plate 350 is larger than the upper surface of the guide plate 330.

[0043] The discharge plate 350 can certainly receive the liquid medicine left from the guide plate 330 and filter it again through the second filter screen 351 to fully intercept and filter all the liquid medicine.

[0044] Referring to Figure 4 , in a preferred embodiment, one side of the discharge plate 350 is provided with a mesh opening, the second filter screen 351 is obliquely arranged upward, the middle section of the second filter screen 351 is parallelly arranged, the downwardly inclined section of the second filter screen 351 is planarly arranged, and the downwardly inclined section of the discharge plate 350 is provided with a mesh opening. Due to the effect of gravitational acceleration, the liquid medicine contacts and moves on the slope of the upwardly inclined section of the second filter screen 351, so that the liquid medicine can fully contact the filter holes on the second filter screen 351, the impurities in the liquid medicine can be contacted and intercepted to a greater extent, and the filtered liquid medicine of the second filter screen 351 is filtered and discharged again by the downwardly inclined end of the discharge plate 350, improving the filtration effect.

[0045] In the description of the utility model, need understanding is, the term "coaxial", "bottom", "one end", "top", "middle", "the other end", "upper", "one side", "top", "inner", "front", "central", "both ends" and so on indicate the orientation or positional relationship is based on the orientation or positional relationship shown in the drawing, only for the convenience of describing the utility model and simplifying the description, and is not indicate or imply that the device or element indicated must have a particular orientation, be constructed and operated in a particular orientation, therefore can not be understood as a limitation on the utility model.

[0046] In the utility model, unless another explicit provision and limitation, the term "installation", "arrangement", "connection", "fix", "screw joint" and so on should do broad sense understanding, for example, can be fixed connection, also can be detachable connection, or be integrated;Can be mechanical connection, also can be electrical connection;Can be directly connected, also can be indirectly connected through intermediate medium, can be two element internal communication or two element mutual action relationship, unless another explicit limitation, for the ordinary skill in the art, can understand the specific meaning of the above-mentioned term in the utility model according to specific circumstances.

[0047] Although the embodiments of the utility model have been shown and described, for the ordinary skill in the art, can understand that the embodiments can be changed, modified, replaced and changed in many ways without departing from the principles and spirits of the utility model, the scope of the utility model is defined by the appended claims and its equivalents.

Claims

1. A high-purity ritonavir refining device, comprising a carrier unit (100), a primary filtration unit (200) and a fine filtration unit (300), characterized in that: the carrier unit (100) comprises a tank body (110), a narrow-mouth filter screen (120) arranged in the tank body (110), a top plate (130) connected with the tank body (110) above the narrow-mouth filter screen (120), and a discharge pipe (140) obliquely installed at the bottom of the tank body (110); the primary filtration unit (200) comprises a liquid guide cylinder (210) fixedly installed on the upper surface of the top plate (130), a positioning groove (211) arranged at the top of the liquid guide cylinder (210), a sleeve ring (220) inserted into the positioning groove (211), a connecting block (221) fixedly installed on the inner wall of the sleeve ring (220), a filter mechanism (230) fixedly connected with the connecting block (221) inside the liquid guide cylinder (210), a connecting rod (240) fixedly installed on the outer wall of the sleeve ring (220), a limiting block (241) fixedly installed on the end of the connecting rod (240) away from the sleeve ring (220), a support block (250) vertically installed on the upper part of the top plate (130), an electric cylinder (260) arranged towards the liquid guide cylinder (210) on the support block (250), a traction rope (261) connected with the extending end of the electric cylinder (260), and the other end of the traction rope (261) connected with the connecting rod (240); the fine filtration unit (300) comprises a discharge port (310) penetrating through the top plate (130) and the liquid guide cylinder (210), a connecting column (320) fixedly connected with the bottom of the top plate (130), a guide plate (330) obliquely installed below the discharge port (310) and fixedly installed at the bottom of the connecting column (320), the guide plate (330) being provided with an opening on one side, a first filter screen (331) placed on the upper surface of the guide plate (330), a discharge plate (350) obliquely passing through a fixed column (340) and connected with the top plate (130) below the guide plate (330), a second filter screen (351) arranged on the upper surface of the discharge plate (350), and the discharge plate (350) being provided with a mesh opening on one side.

2. The high purity ritonavir refining apparatus according to claim 1, characterized by: The tank body (110) is hollow, the narrow-mouth filter screen (120) is placed above the fixed block fixedly installed on the inner wall of the tank body (110), and the upper surface area of the narrow-mouth filter screen (120) is greater than the upper surface area of the fine filtration unit (300).

3. The high purity ritonavir refining apparatus according to claim 1, characterized by: The extending end of the electric cylinder (260) is not in contact with the liquid guide cylinder (210), and the bottom of the filter mechanism (230) is provided with a narrow-mouth filter screen.

4. The high purity ritonavir purification apparatus of claim 1, wherein: The discharge port (310) is directly above the first filter screen (331), and the lower surface area of the discharge port (310) is smaller than the lower surface area of the first filter screen (331).

5. A high purity ritonavir purification apparatus according to claim 4, wherein: The first filter screen (331) is placed inside the guide plate (330), and the first filter screen (331) is blocked by the connecting column (320) installed on the guide plate (330).

6. A high purity ritonavir purification apparatus according to claim 5, wherein: The discharge plate (350) is below the guide plate (330), and the upper surface area of the discharge plate (350) is greater than the upper surface area of the guide plate (330).

7. The high purity ritonavir purification apparatus of claim 1, wherein: The upwardly inclined section of the second filter screen (351) is inclined, the middle section of the second filter screen (351) is parallel, the downwardly inclined section of the second filter screen (351) is flat, and the downwardly inclined section of the discharge plate (350) is a mesh opening.

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