Stainless steel reaction tank reinforced stirring mechanism for ceftriaxone sodium production

Abstract

The utility model belongs to the technical field of medicine production equipment, and particularly relates to an enhanced stirring mechanism of a stainless steel reaction tank for producing ceftriaxone sodium, which comprises a tank body, a gear motor, a guide cylinder, a first stirring shaft and two second stirring shafts, the guide cylinder is arranged in the tank body, two fixing plates are fixed to the bottom of the guide cylinder, first cross rods are arranged on the opposite sides of the two fixing plates, the first stirring shaft vertically penetrates through the guide cylinder, the top end of the first stirring rod is in transmission connection with an output shaft of the gear motor, and an impeller is arranged on the first stirring shaft; mounting seats are arranged at the bottom ends of the first stirring shafts, second transverse rods are arranged on the mounting seats, the two second stirring shafts are in transmission connection with the first stirring shafts respectively, and stirring paddles are arranged on the second stirring shafts. According to the device, the stirring effect can be improved, materials are mixed more uniformly, the phenomenon of inconsistent uniformity of the materials is avoided, and the product quality is improved.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the technical field of medical production equipment, and concretely relates to a stainless steel reaction tank intensification stirring mechanism for ceftriaxone sodium production. BACKGROUND

[0002] Ceftriaxone sodium is a beta-lactam antibiotic and cephalosporin, which is used for lower respiratory tract infection, urinary tract and biliary tract infection, abdominal cavity infection, pelvic cavity infection, skin and soft tissue infection, bone and joint infection, septicemia, meningitis and surgical period infection prevention caused by sensitive pathogenic bacteria, and can treat simple gonorrhea with a single dose. 18 H 16 N8Na2O7S3, and its antibacterial spectrum is similar to that of cefotaxime sodium. It has strong effect on Escherichia coli, pneumonitis bacillus, indole-positive proteus, influenza bacillus, serratia, meningococcus and gonococcus, moderate sensitivity to pneumococcus, streptococcus and staphylococcus aureus, certain effect on pseudomonas aeruginosa, and drug resistance to enterococcus, methicillin-resistant staphylococcus and most fragile bacteroides.

[0003] At present, in the process of producing ceftriaxone sodium by adopting the prior art such as the preparation method of ceftriaxone sodium disclosed in CN112679524B, the stainless steel reaction tank is generally used to mix and stir each component material. When the fourth part is reached, the mixed liquid prepared in the first three parts needs to be mixed together, and a certain amount of triethylamine is added for stirring to obtain the first reaction liquid. However, the stirring mechanism structure of the existing stainless steel reaction tank is relatively simple, the stirring effect is not good, the material mixing is not uniform enough, especially the uniformity of the material at the center and edge of the tank body, as well as the upper and lower positions of the tank body is inconsistent, which leads to the product quality cannot be guaranteed.

[0004] Therefore, it is urgent to improve. UTILITY MODEL CONTENTS

[0005] In view of the above-mentioned defects existing in the prior art, the utility model provides a kind of ceftriaxone sodium production with stainless steel reaction tank intensification stirring mechanism, including jar body, speed reducer motor, flow guide cylinder, first stirring shaft and two second stirring shafts, the top of inside jar body is fixedly provided with baffle, speed reducer motor is fixedly arranged at the top of the outside jar body, flow guide cylinder is vertically arranged in the inside jar body, two fixed plates are fixed on the left side and the right side of flow guide cylinder bottom, and the opposite side of two fixed plates is provided with a plurality of first cross bars, first stirring shaft is vertically arranged in flow guide cylinder, the top of first stirring rod passes through the top wall of baffle and jar body and is connected with the output shaft transmission of speed reducer motor, and first stirring shaft is rotatably connected with baffle, the part of first stirring shaft in flow guide cylinder is provided with impeller, the bottom of first stirring shaft is fixed with mounting seat, a plurality of second cross bars are provided on mounting seat, two second stirring shafts are separately arranged on the left side and the right side of first stirring shaft, the top of two second stirring shafts all passes through baffle and is respectively connected with first stirring shaft transmission, and the part of second stirring shaft below baffle is provided with stirring paddle.

[0006] Optionally, the top of the jar body is provided with a feed pipe, and the connecting port between the feed pipe and the jar body is located below the baffle. The bottom of the jar body is provided with a discharge port, and a valve is arranged at the discharge port.

[0007] Optionally, the inside of the flow guide cylinder is provided with a downwardly inclined flow guide plate, and the flow guide plate is provided with a flow guide groove.

[0008] Specifically, the flow guide plate can increase the resistance of liquid material flow, so that the liquid material is mixed more uniformly.

[0009] Optionally, the part of the first stirring shaft above the baffle is provided with a first gear, and the part of the two second stirring shafts above the baffle is provided with a second gear meshing with the first gear.

[0010] Optionally, the outer wall of the jar body is provided with an inspection port and an inspection door.

[0011] Specifically, the inspection port facilitates the maintenance of the inside of the jar body by the staff.

[0012] Optionally, the first cross bars on the fixed plate and the second cross bars on the mounting seat are arranged alternately.

[0013] The utility model also includes other components that can enable a kind of ceftriaxone sodium production with stainless steel reaction tank intensification stirring mechanism to be normally used, which are all conventional technical means in the field. In addition, the devices or components not specified in the utility model adopt conventional technical means in the field, such as speed reducer motor and valve.

[0014] The utility model discloses a working principle is, when using, adds each group component liquid material in the jar body, starts the speed reducer, drives the rotation of first stirring shaft, mixes and stirs the liquid material in the flow guide tube inside, makes the liquid material in the flow guide tube flow from top to bottom, simultaneously, first stirring shaft drives the rotation of two second stirring shafts on both sides, mixes and stirs the liquid material outside the flow guide tube, makes the liquid material outside the flow guide tube flow from bottom to top, and the flow guide tube flows according to the specific path of guiding fluid, optimizes the fluid dynamics characteristic in the jar body, reduces the generation of vortex and dead angle, makes fluid form more orderly and efficient circulation flow in the jar body, thereby improves mixing efficiency, enhances the stirring effect, and the flow guide tube can also reduce the opportunity of fluid short circuit, ensures that all materials can pass through the strong mixing area in the flow guide tube, further improves mixing quality, makes the material mixing more evenly, in addition, the first cross bar and the second cross bar staggered under the flow guide tube can strengthen the flow process of the fluid in the stirring jar body, and strong interaction can be generated between the first cross bar and the second cross bar, promotes the uniform distribution between liquid.

[0015] The utility model discloses the beneficial effect is, through jar body, speed reducer, flow guide tube, first stirring shaft and two second stirring shafts, ensure that all materials can pass through the strong mixing area in the flow guide tube, thereby improves mixing efficiency, can also make the fluid in the jar body can be fully mixed, thereby enhances the stirring effect, makes the material mixing more evenly, avoids the phenomenon that the uniformity of material appears the inconsistency, improves product quality. DRAWINGS

[0016] The utility model is further explained below in combination with the drawings and examples.

[0017] Fig. 1 It is the whole structure schematic diagram of the utility model.

[0018] Fig. 2 It is the local solid structure schematic diagram of the flow guide tube of the utility model.

[0019] In the drawing: 1. jar body, 2. speed reducer, 3. flow guide tube, 4. first stirring shaft, 5. second stirring shaft, 6. baffle, 7. flow guide plate, 8. flow guide groove, 9. fixed plate, 10. first cross bar, 11. first gear, 12. impeller, 13. mounting seat, 14. second cross bar, 15. second gear, 16. stirring paddle, 17. feed pipe, 18. discharge port, 19. inspection port. CONCRETE IMPLEMENTATION

[0020] The utility model is clearly described below in combination with the drawings and specific embodiments in the embodiments of the utility model, and the description herein is only used to explain the utility model, but not as a limitation on the utility model. Based on the embodiments in the utility model, all other embodiments obtained by the person skilled in the art without creative labor, any modification, equivalent replacement, improvement, etc. made, should be included in the protection scope of the utility model.

[0021] Embodiment

[0022] As Figs. 1-2 shown, the utility model embodiment provides a kind of stainless steel reaction tank intensification stirring mechanism for ceftriaxone sodium production, including jar body 1, speed reducer motor 2, flow guide cylinder 3, first stirring shaft 4 and two second stirring shafts 5, the top of inside jar body 1 is fixedly arranged with baffle 6, speed reducer motor 2 is fixedly arranged at the top of the outside of jar body 1, flow guide cylinder 3 is vertically arranged in the inside of jar body 1, the inside of flow guide cylinder 3 is provided with downwardly inclined flow guide plate 7, and flow guide groove 8 is provided on flow guide plate 7, flow guide plate 7 can increase the resistance of liquid material flow, make liquid material mixing more uniform, and two fixed plates 9 are fixed on the left and right sides of the bottom of flow guide cylinder 3, and a plurality of first cross bars 10 are arranged on the opposite sides of the two fixed plates 9, first stirring shaft 4 is vertically arranged in flow guide cylinder 3, the top of first stirring rod passes through baffle 6 and the top wall of jar body 1 and is connected with the output shaft transmission of speed reducer motor 2, and first stirring shaft 4 is rotatably connected with baffle 6, and the part of first stirring shaft 4 above baffle 6 is provided with first gear 11, and the part of first stirring shaft 4 in flow guide cylinder 3 is provided with impeller 12, and impeller 12 does not interfere with flow guide plate 7 on flow guide cylinder 3, and the bottom of first stirring shaft 4 is fixed with mounting seat 13, a plurality of second cross bars 14 are arranged on mounting seat 13, and second cross bar 14 and first cross bar 10 on fixed plate 9 are arranged alternately, two second stirring shafts 5 are arranged on the left and right sides of first stirring shaft 4, and the top of two second stirring shafts 5 all passes through baffle 6 and is respectively provided with second gear 15 meshing with first gear 11, and the part of second stirring shaft 5 below baffle 6 is provided with stirring paddle 16, and stirring paddle 16 does not interfere with flow guide cylinder 3.

[0023] In addition, the top of jar body 1 is provided with feed pipe 17, and the connecting port between feed pipe 17 and jar body 1 is below baffle 6, the bottom of jar body 1 is provided with discharge port 18, and valve is provided at discharge port 18. Inspection port 19 and inspection door are arranged on the outer wall of jar body 1, and inspection port 19 is convenient for staff to overhaul the inside of jar body 1.

[0024] The working principle of the utility model is that when using, each group of liquid material is added into the tank body 1, the reduction motor 2 is started, the first stirring shaft 4 is driven to rotate, the liquid material inside the flow guide cylinder 3 is mixed and stirred, the liquid material inside the flow guide cylinder 3 flows from top to bottom, meanwhile the first stirring shaft 4 drives the two second stirring shafts 5 on both sides to rotate, the liquid material outside the flow guide cylinder 3 is mixed and stirred, the liquid material outside the flow guide cylinder 3 flows from bottom to top, the flow guide cylinder 3 guides the fluid to flow along a specific path, optimizes the fluid dynamics characteristics inside the tank body 1, reduces the generation of vortex and dead angle, makes the fluid form more orderly and efficient circulating flow inside the tank body 1, thereby improves the mixing efficiency, enhances the stirring effect, meanwhile the flow guide cylinder 3 can also reduce the opportunity of fluid short circuit, ensures that all materials can pass through the strong mixing area inside the flow guide cylinder 3, further improves the mixing quality, makes the material mixing more uniform, in addition, the first cross bar 10 and the second cross bar 14 staggered arranged below the flow guide cylinder 3 can strengthen the flow process of the fluid at the bottom of the stirring tank body 1, and the first cross bar 10 and the second cross bar 14 can produce strong interaction, promotes the uniform distribution between the liquid.

[0025] The above has described the embodiments of the utility model, the above description is exemplary, is not exhaustive, and is not limited to the disclosed embodiments. Many modifications and changes are obvious to those skilled in the art without departing from the scope and spirit of the described embodiments.

Claims

1. A reinforced stirring mechanism of a stainless steel reaction tank for the production of ceftriaxone sodium, comprising a tank body, a speed reducer motor, a flow guide cylinder, a first stirring shaft and two second stirring shafts, characterized in that: The top end of the inside of the tank body is fixedly provided with a partition plate, a speed reducer motor is fixedly arranged above the outside of the tank body, a flow guide cylinder is vertically arranged in the inside of the tank body, two fixed plates are fixedly arranged on the left and right sides of the bottom of the flow guide cylinder, a plurality of first cross bars are arranged on the opposite sides of the two fixed plates, a first stirring shaft is vertically arranged in the flow guide cylinder, the top end of the first stirring rod penetrates through the partition plate and the top wall of the tank body and is connected with the output shaft of the speed reducer motor in transmission, the first stirring shaft is rotatably connected with the partition plate, the part of the first stirring shaft in the flow guide cylinder is provided with an impeller, the bottom end of the first stirring shaft is fixedly provided with a mounting seat, a plurality of second cross bars are arranged on the mounting seat, two second stirring shafts are arranged on the left and right sides of the first stirring shaft, the top ends of the two second stirring shafts penetrate through the partition plate and are respectively connected with the first stirring shaft in transmission, the part of the second stirring shaft below the partition plate is provided with a stirring paddle.

2. The ceftriaxone sodium production stainless steel reaction tank reinforced stirring mechanism according to claim 1, characterized in that: The top of the tank body is provided with a feeding pipe, and the connecting port between the feeding pipe and the tank body is located below the partition plate, the bottom of the tank body is provided with a discharge port, and the discharge port is provided with a valve.

3. The ceftriaxone sodium production stainless steel reaction tank reinforced stirring mechanism according to claim 2, characterized in that: The inside of the flow guide cylinder is provided with a downwardly inclined flow guide plate, and the flow guide plate is provided with a flow guide groove.

4. The ceftriaxone sodium production stainless steel reaction tank reinforced stirring mechanism according to claim 3, characterized in that: The part of the first stirring shaft above the partition plate is provided with a first gear, and the parts of the two second stirring shafts above the partition plate are provided with second gears meshing with the first gear.

5. The ceftriaxone sodium production stainless steel reaction tank reinforced stirring mechanism according to claim 4, characterized in that: The outer wall of the tank body is provided with an inspection port and an inspection door.

6. The ceftriaxone sodium production stainless steel reaction tank reinforced stirring mechanism according to claim 5, characterized in that: The first cross bars on the fixed plates and the second cross bars on the mounting seat are arranged alternately.

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