Preparation equipment for ribociclib tablets

Abstract

The utility model discloses preparation equipment for ribociclib tablets, which belongs to the technical field of tablet preparation and comprises a base, the upper surface of the base is fixedly connected with a plurality of support rods, the upper ends of the support rods are fixedly connected with a same storage tank, one side of the surface of the storage tank is fixedly connected with a processing component, and the processing component is fixedly connected with a plurality of blades. The upper end of the storage tank is fixedly connected with a tank cover, the lower surface of the tank cover is rotatably connected with a mixing assembly, the middle end of the upper surface of the base is fixedly connected with a transfer box, and the front surface of the transfer box is fixedly connected with a drying assembly. The ribociclib tablet crushing device is provided with the processing assembly, raw materials of ribociclib tablets are effectively and rapidly crushed, the uniformity of raw material particles is ensured, the mixing process of the raw materials, auxiliary materials and additives is accelerated by arranging the mixing assembly, the materials are prevented from being adhered to the inner wall of the tank body, excessive moisture in the materials is effectively removed by arranging the drying assembly, and the drying efficiency is improved. The hardness and the stability of the tablet are improved.

Description

Technical Field

[0001] This utility model relates to the field of tablet preparation technology, and in particular to a preparation device for ribociclib tablets. Background Technology

[0002] Ribocitabine, also known as ribucine, is a novel targeted small molecule drug that selectively inhibits the activity of cyclin-dependent kinases, blocks the phosphorylation of retinoblastoma proteins, and reduces the proliferation of breast cancer cell lines, thereby exerting an anti-tumor effect.

[0003] In traditional production equipment, the three steps of raw material processing, mixing, and drying are often handled separately, which not only increases the complexity of operation and labor costs, but may also lead to changes in the properties of raw materials and low production efficiency. In addition, the storage containers of traditional equipment may lack anti-sticking design, causing materials to easily stick to the inner wall of the container during storage, resulting in waste and cleaning difficulties. In order to solve the above problems, this utility model provides a preparation equipment for Rebociclib tablets. Utility Model Content

[0004] The purpose of this invention is to address the shortcomings of existing technologies by proposing a device for preparing ribociclib tablets.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A device for preparing ribociclib tablets includes a base, several support rods fixedly connected to the upper surface of the base, the upper ends of the support rods fixedly connected to the same storage tank, a processing component fixedly connected to one side of the surface of the storage tank, a feeding valve pipe fixedly connected to the other side of the surface of the storage tank, a tank cover fixedly connected to the upper end of the storage tank, a mixing component rotatably connected to the lower surface of the tank cover, a transfer box fixedly connected to the middle of the upper surface of the base, a drying component fixedly connected to the front of the transfer box, mounting seats fixedly connected to both sides of the upper surface of the transfer box, and electric heating plates fixedly connected to the opposite sides of the two mounting seats.

[0007] As a further improvement of this utility model, the processing assembly includes a feeding seat fixedly connected to one side of the surface of the storage tank. A processing box is fixedly connected to the upper end of the feeding seat. Two crushing rollers are rotatably connected inside the processing box. Two transmission gears are rotatably connected to one side of the processing box, and the two transmission gears mesh with each other. One end of the crushing roller is fixedly connected to the transmission gear. A drive motor is fixedly connected to the other side of the processing box. The power end of the drive motor is fixedly connected to one of the crushing rollers. A feeding cover is fixedly connected to the upper surface of the processing box. Reinforcing rods are fixedly connected to both sides of the lower end of the feeding seat. The other end of the reinforcing rods is fixedly connected to the storage tank.

[0008] As a further improvement of this utility model, the mixing component includes a transmission rod rotatably connected to the lower surface of the can lid, several mixing rods are fixedly connected to the surface of the transmission rod, scraper rods are fixedly connected to both sides of the surface of the transmission rod, a rotary motor is fixedly connected to the upper surface of the can lid, and the power end of the rotary motor is fixedly connected to the transmission rod.

[0009] As a further improvement of this utility model, the drying assembly includes a transport pipe fixedly connected to the front of the transfer box, a transport motor fixedly connected to the back of the transfer box, a spiral conveying rod fixedly connected to the power end of the transport motor, and the spiral conveying rod rotatably connected inside the transport pipe.

[0010] As a further improvement of this utility model, the upper end of the adapter box is fixedly connected to a discharge valve pipe, and the upper end of the discharge valve pipe is fixedly connected to the storage tank.

[0011] As a further improvement of this utility model, a measuring cylinder is fixedly connected to the upper end of the feeding valve pipe.

[0012] The beneficial effects of this utility model are:

[0013] By setting up the processing components, during use, the two crushing rollers can operate in opposite directions within the processing box through the precise cooperation of the drive motor and two transmission gears, thereby effectively and quickly crushing the raw materials of Rebociclib tablets. This not only improves the crushing efficiency but also ensures the uniformity of the raw material particles, laying a good foundation for the subsequent mixing process.

[0014] By setting up a mixing component, during use, the rotary motor drives the mixing rod and scraper to rotate synchronously via the transmission rod. The rotation of the mixing rod accelerates the mixing process of raw materials, auxiliary materials and additives, ensuring the uniform distribution of components. The scraper can effectively prevent materials from sticking to the inner wall of the tank during rotation, which not only improves the utilization rate of materials, but also reduces the difficulty and frequency of cleaning work, and helps to maintain the cleanliness of the production environment and the long-term stable operation of the equipment.

[0015] By incorporating a drying component, the rotation of the screw conveyor not only enables continuous transport of the mixed materials but also ensures the uniformity and stability of the materials during transport, providing a reliable material supply for subsequent tablet processing. Simultaneously, the electric heating plate dries the mixed materials during their movement, effectively removing excess moisture and preventing tablet quality issues caused by damp materials, thus improving the hardness and stability of the tablets.

[0016] By setting up a measuring cylinder, the amount of excipients and additives added can be precisely controlled during use, avoiding the problem of unstable tablet quality caused by inaccurate addition. By observing the amount in the measuring cylinder and opening the feeding valve after the appropriate amount is reached, a precise and convenient addition process is achieved.

[0017] In summary, this invention achieves efficient, stable, and continuous production of ribociclib tablets, improving production efficiency and product quality, reducing production costs, and enhancing equipment utilization and flexibility. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the structure of a device for preparing ribociclib tablets according to the present invention.

[0019] Figure 2 This is a schematic diagram of the processing component of a device for preparing ribociclib tablets according to the present invention.

[0020] Figure 3 This is a schematic diagram of the mixing component of a preparation device for ribociclib tablets proposed in this utility model.

[0021] Figure 4 This is a schematic diagram of the drying component of a device for preparing ribociclib tablets according to the present invention.

[0022] In the diagram: 1. Base, 2. Support rod, 3. Storage tank, 4. Feeding valve pipe, 5. Tank cover, 6. Transfer box, 7. Mounting seat, 8. Electric heating plate, 9. Feeding seat, 10. Processing box, 11. Crushing roller, 12. Transmission gear, 13. Drive motor, 14. Feeding cover, 15. Transmission rod, 16. Mixing rod, 17. Scraper, 18. Rotary motor, 19. Conveying pipe, 20. Conveying motor, 21. Screw conveyor rod, 22. Discharge valve pipe, 23. Measuring cylinder, 24. Reinforcing rod. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0024] Reference Figures 1-4 A device for preparing ribociclib tablets includes a base 1, several support rods 2 fixedly connected to the upper surface of the base 1, the upper ends of the support rods 2 fixedly connected to the same storage tank 3, a processing component fixedly connected to one side of the surface of the storage tank 3, a feeding valve pipe 4 fixedly connected to the other side of the surface of the storage tank 3, a tank cover 5 fixedly connected to the upper end of the storage tank 3, a mixing component rotatably connected to the lower surface of the tank cover 5, a transfer box 6 fixedly connected to the middle of the upper surface of the base 1, a drying component fixedly connected to the front of the transfer box 6, mounting seats 7 fixedly connected to both sides of the upper surface of the transfer box 6, and an electric heating plate 8 fixedly connected to the opposite side of the two mounting seats 7.

[0025] In this invention, the processing assembly includes a feed seat 9 fixedly connected to one side of the surface of the storage tank 3. The design of the feed seat 9 ensures that the raw materials can enter the processing flow smoothly and accurately. A processing box 10 is fixedly connected to the upper end of the feed seat 9. Two crushing rollers 11 are rotatably connected inside the processing box 10. The two crushing rollers 11 can efficiently crush raw materials of various particle sizes through precise gap adjustment, ensuring the uniformity of product quality. Two transmission gears 12 are rotatably connected to one side of the processing box 10. The two transmission gears 12 mesh with each other. One end of the crushing roller 11 is fixedly connected to the transmission gear 12. The gear transmission method not only ensures... The synchronous operation of the crushing roller 11 is ensured, and the crushing efficiency is improved. A drive motor 13 is fixedly connected to the other side of the processing box 10. The power end of the drive motor 13 is fixedly connected to one of the crushing rollers 11. A feeding cover 14 is fixedly connected to the upper surface of the processing box 10. The design of the feeding cover 14 makes it easy for the operator to safely and quickly add raw materials, while preventing dust leakage during the processing. Reinforcing rods 24 are fixedly connected to both sides of the lower end of the feeding seat 9. The other end of the reinforcing rod 24 is fixedly connected to the storage tank 3. The reinforcing rod 24 effectively enhances the stability of the entire structure and ensures reliability and durability in long-term operation.

[0026] The mixing assembly includes a drive rod 15 rotatably connected to the lower surface of the can lid 5. Several mixing rods 16 are fixedly connected to the surface of the drive rod 15. These mixing rods 16 are angled to ensure all-round mixing of materials inside the can. Scrapers 17 are fixedly connected to both sides of the surface of the drive rod 15. The design of the scrapers 17 effectively prevents materials from adhering to the inner wall of the can, improving mixing efficiency and product quality. A rotary motor 18 is fixedly connected to the upper surface of the can lid 5. The power end of the rotary motor 18 is fixedly connected to the drive rod 15. As the power source of the mixing assembly, the rotary motor 18 provides a stable and controllable rotation speed, ensuring the consistency and repeatability of the mixing process.

[0027] The drying assembly includes a conveying pipe 19 fixedly connected to the front of the transfer box 6, a conveying motor 20 fixedly connected to the back of the transfer box 6, a spiral conveying rod 21 fixedly connected to the power end of the conveying motor 20, and the spiral conveying rod 21 rotatably connected inside the conveying pipe 19. Through its unique spiral structure, the spiral conveying rod 21 can efficiently convey materials from one end to the other end, while achieving uniform heating and drying effects.

[0028] The upper end of the transfer box 6 is fixedly connected to the discharge valve pipe 22. Both the feeding valve pipe 4 and the discharge valve pipe 22 are equipped with solenoid valves. The upper end of the discharge valve pipe 22 is fixedly connected to the storage tank 3. The upper end of the feeding valve pipe 4 is fixedly connected to the measuring cylinder 23. The design of the measuring cylinder 23 enables the operator to accurately control the amount of raw materials added, thereby improving the accuracy and controllability of the production process.

[0029] In use, the drive motor 13 is first started, which drives two crushing rollers 11 to rotate in opposite directions within the processing box 10 via two transmission gears 12. The raw material for Rebociclib tablets is added between the two crushing rollers 11 within the processing box 10 through the feeding cover 14. After crushing, the raw material enters the storage tank 3 through the feeding seat 9. Then, excipients and additives are added to the measuring cylinder 23. The amount added is observed through the measuring cylinder 23. Once the appropriate amount is reached, the feeding valve pipe 4 is opened to allow the excipients and additives to enter the storage tank 3. The rotary motor 18 is started, driving the transmission rod 15 to rotate. The transmission rod 15 drives the mixing rod 16 and scraper 17 to rotate. The mixing rod 16 can... The mixing of raw materials, excipients and additives is accelerated. The scraper 17 can prevent material from sticking to the inner wall of the storage tank 3. At the same time, the electric heating plate 8 is activated to preheat the transport pipe 19. After the mixing is completed, the discharge valve pipe 22 is opened to allow the mixed material to enter the transfer box 6. The transport motor 20 is activated to drive the screw conveyor 21 to rotate in the transport pipe 19. The rotation of the screw conveyor 21 can drive the mixed material to move in the transport pipe 19, thereby discharging the mixed material. At the same time, the electric heating plate 8 dries the mixed material moving in the transport pipe 19. The processed mixed material is discharged from the other end of the transport pipe 19 and sent to the tablet press for tablet processing.

[0030] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. An apparatus for preparing ribociclib tablets, comprising a base (1), characterized in that, Several support rods (2) are fixedly connected to the upper surface of the base (1). The upper ends of the several support rods (2) are fixedly connected to the same storage tank (3). A processing component is fixedly connected to one side of the surface of the storage tank (3). A feeding valve pipe (4) is fixedly connected to the other side of the surface of the storage tank (3). A tank cover (5) is fixedly connected to the upper end of the storage tank (3). A mixing component is rotatably connected to the lower surface of the tank cover (5). A transfer box (6) is fixedly connected to the middle of the upper surface of the base (1). A drying component is fixedly connected to the front of the transfer box (6). Mounting seats (7) are fixedly connected to both sides of the upper surface of the transfer box (6). An electric heating plate (8) is fixedly connected to the opposite side of the two mounting seats (7).

2. The apparatus for preparing ribociclib tablets according to claim 1, characterized in that, The processing assembly includes a feeding seat (9) fixedly connected to one side of the surface of the storage tank (3). A processing box (10) is fixedly connected to the upper end of the feeding seat (9). Two crushing rollers (11) are rotatably connected inside the processing box (10). Two transmission gears (12) are rotatably connected to one side of the processing box (10). The two transmission gears (12) mesh with each other. One end of the crushing roller (11) is fixedly connected to the transmission gear (12). A drive motor (13) is fixedly connected to the other side of the processing box (10). The power end of the drive motor (13) is fixedly connected to one of the crushing rollers (11). A feeding cover (14) is fixedly connected to the upper surface of the processing box (10). Reinforcing rods (24) are fixedly connected to both sides of the lower end of the feeding seat (9). The other end of the reinforcing rods (24) is fixedly connected to the storage tank (3).

3. The apparatus for preparing ribociclib tablets according to claim 1, characterized in that, The mixing assembly includes a transmission rod (15) rotatably connected to the lower surface of the can lid (5), several mixing rods (16) are fixedly connected to the surface of the transmission rod (15), scraper rods (17) are fixedly connected to both sides of the surface of the transmission rod (15), a rotary motor (18) is fixedly connected to the upper surface of the can lid (5), and the power end of the rotary motor (18) is fixedly connected to the transmission rod (15).

4. The apparatus for preparing ribociclib tablets according to claim 1, characterized in that, The drying assembly includes a transport pipe (19) fixedly connected to the front of the adapter box (6), a transport motor (20) fixedly connected to the back of the adapter box (6), a spiral conveying rod (21) fixedly connected to the power end of the transport motor (20), and the spiral conveying rod (21) rotatably connected inside the transport pipe (19).

5. The apparatus for preparing ribociclib tablets according to claim 1, characterized in that, The upper end of the transfer box (6) is fixedly connected to the discharge valve pipe (22), and the upper end of the discharge valve pipe (22) is fixedly connected to the storage tank (3).

6. The apparatus for preparing ribociclib tablets according to claim 1, characterized in that, A measuring cylinder (23) is fixedly connected to the upper end of the feeding valve pipe (4).

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