Cerebrospinal fluid protein qualitative experiment detection test tube and reagent set
By designing a test tube for qualitative analysis of cerebrospinal fluid proteins with alternating black and transparent walls, containing phenol solution and equipped with light-proof storage, the problems of cumbersome operation and phenol solution evaporation in existing technologies are solved, achieving efficient and accurate detection results.
Patent Information
- Application Number
- CN202421646661.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-12
- Publication Date
- 2026-01-23
- Estimated Expiration
- 2034-07-12
AI Technical Summary
Existing qualitative tests for cerebrospinal fluid proteins are cumbersome to perform, and the volatile nature of phenol solutions affects the accuracy of the test results, making result interpretation complex.
A test tube for qualitative analysis of cerebrospinal fluid proteins was designed, featuring alternating black and transparent tube walls, containing a 5% phenol solution, providing a black background for observation, and incorporating light-blocking stickers and light-protected storage to simplify the operation process and prevent phenol solution evaporation.
It improves detection accuracy and efficiency, simplifies operation procedures, reduces the risk of phenol solution volatilization, and ensures accurate results.
Smart Images
Figure CN223818703U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to the field of biotechnology especially, relate to a cerebrospinal fluid protein qualitative experiment detection test tube and reagent set. BACKGROUND
[0002] Cerebrospinal fluid protein qualitative test is a common method for detecting cerebrospinal fluid immunoglobulin. In the test, globulin in cerebrospinal fluid is combined with phenol to form insoluble protein salt and sink, resulting in white turbidity or precipitation, which is positive in Pandy test.
[0003] During operation, 2-3ml of 5% phenol solution reagent is taken and placed in an observation container, and 1-2 drops of cerebrospinal fluid is added by using a capillary dropper, and the result is observed immediately. If the sample is clear and transparent without fog, the result is negative. If the sample is slightly white fog, the result is very weakly positive. If the sample result is positive, (+) is gray cloud, (2+) is white turbidity, (3+) is white thick flocculent precipitate, and (4+) is white clot.
[0004] 5% phenol solution needs to be taken from the storage container for each sample detection. On the one hand, the operation is complicated, and on the other hand, repeated opening of the storage container can cause phenol evaporation, resulting in a decrease in the concentration of phenol solution and affecting the accuracy of the detection result. In addition, a suitable color background needs to be found to observe the very weakly positive and positive results, which increases the operation complexity. UTILITY MODEL CONTENT
[0005] Therefore, the utility model aims to overcome the deficiencies in the prior art and provide a cerebrospinal fluid protein qualitative experiment detection test tube and reagent set.
[0006] The utility model provides the following technical scheme:
[0007] On the one hand, the embodiment of the application provides a cerebrospinal fluid protein qualitative experiment detection test tube, which comprises a test tube body, the tube wall of the test tube body comprises one or more black tube walls and one or more transparent tube walls, and the black tube walls and the transparent tube walls are alternately distributed.
[0008] In one embodiment, the black tube walls and the transparent tube walls extend along the axial direction of the test tube body, and the black tube walls and the transparent tube walls are sequentially distributed along the circumference of the axial direction of the test tube body.
[0009] In one embodiment, the black tube walls extend around the peripheral surface of the test tube body, the transparent tube walls extend around the peripheral surface of the test tube body, and the transparent tube walls and the black tube walls are sequentially distributed along the axial direction of the test tube body.
[0010] In one embodiment, the cerebrospinal fluid protein qualitative test test tube further comprises a light shielding sticker, which is attached to the outer circumferential surface of the transparent tube wall.
[0011] In one embodiment, the test tube body internally stores a 5% phenol solution.
[0012] In one embodiment, the cerebrospinal fluid protein qualitative test test tube further comprises a plug, which is installed at the opening of the test tube body.
[0013] In a second aspect, the embodiments of the present application also provide a cerebrospinal fluid protein qualitative test reagent kit, which comprises a storage member and the cerebrospinal fluid protein qualitative test test tube as described in any of the above embodiments; the storage member has a storage space, the storage member is made of light shielding material; and the cerebrospinal fluid protein qualitative test test tube is arranged in the storage space.
[0014] In one embodiment, the cerebrospinal fluid protein qualitative test reagent kit further comprises a sampling member, which is arranged in the storage space and used for sucking a cerebrospinal fluid sample for detection and adding into the test tube body.
[0015] In one embodiment, the storage member is a box structure, and the inner wall of the box structure is black.
[0016] In one embodiment, the storage member is a packaging bag, and the inner wall of the packaging bag is black.
[0017] The cerebrospinal fluid protein qualitative test test tube provided by the embodiments of the present application has the following advantages:
[0018] The black tube wall can provide a black background for observing the sample, so that the sample is more obvious, the detection precision is improved, and when observing the result, it is not necessary to find other black backgrounds, the test efficiency is improved, and the observer can observe through the transparent tube wall, and the transparent tube wall can reduce the interference on the observation result.
[0019] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the following preferred embodiments are described in detail below, and the accompanying drawings are described as follows. BRIEF DESCRIPTION OF DRAWINGS
[0020] In order to more clearly illustrate the technical scheme of the embodiments of the present application, the following will briefly introduce the drawings needed to be used in the embodiments, and it should be understood that the following drawings only show some embodiments of the present application, and therefore should not be regarded as a limitation on the scope, and for those skilled in the art, other related drawings can also be obtained without creative labor on the basis of these drawings.
[0021] Figure 1 FIG. 1 shows a perspective view of one embodiment of a test tube for qualitative detection of cerebrospinal fluid protein according to the present application;
[0022] Figure 2 FIG. 2 shows a side view of one embodiment of a test tube for qualitative detection of cerebrospinal fluid protein according to the present application;
[0023] Figure 3 FIG. 3 shows a perspective view of another embodiment of a test tube for qualitative detection of cerebrospinal fluid protein according to the present application;
[0024] Figure 4 FIG. 4 shows a perspective view of another embodiment of a test tube for qualitative detection of cerebrospinal fluid protein according to the present application;
[0025] Figure 5 FIG. 5 shows a perspective view of another embodiment of a test tube for qualitative detection of cerebrospinal fluid protein according to the present application.
[0026] Main component symbol explanation:
[0027] 100 - test tube body; 110 - black tube wall; 120 - transparent tube wall;
[0028] 200 - phenol solution. DETAILED DESCRIPTION
[0029] Embodiments of the present application are described in detail below with reference to the attached drawing figures, wherein the embodiments of the application are shown by way of examples. The same or similar components are denoted by the same reference numerals throughout the attached drawing figures. The embodiments described below are exemplary only, and are not to be construed as limiting the present application.
[0030] It should be noted that when an element is referred to as being "on" another element, it can be directly on the other element or intervening elements can also be present. In contrast, when an element is referred to as being "directly on" another element, there are no intervening elements present. Like reference numerals refer to like elements throughout the specification and no additional structures are described herewith for like reference numerals where already been described. The terms "vertical", "horizontal", "left", "right" and the like as used herein are used for explanation only, not to limit the present application.
[0031] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.
[0032] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.
[0033] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein in the template description is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.
[0034] In the first aspect, embodiments of this application provide a cerebrospinal fluid protein qualitative test tube, which can be used for cerebrospinal fluid protein qualitative tests. Using the cerebrospinal fluid protein qualitative test tube provided in this embodiment facilitates the observation of experimental results, simplifies experimental operations, and improves experimental efficiency and the accuracy of detection results.
[0035] like Figures 1 to 5 As shown, the test tube for qualitative analysis of cerebrospinal fluid proteins includes a test tube body 100. The tube body 100 has one or more black tube walls 110 and one or more transparent tube walls 120, with the black tube walls 110 and transparent tube walls 120 alternating.
[0036] The black tube wall 110 and the transparent tube wall 120 can be set to extend along the axial direction or circumferential direction of the test tube body 100. Of course, they can also be set to extend along an irregular path.
[0037] In this embodiment, the proportion of the black tube wall 110 and the transparent tube wall 120 to the total area of the test tube body 100 is not limited. The ratio of the areas of the black tube wall 110 and the transparent tube wall 120 can be 1:1, 2:1, 1:2 or 1:3, etc.
[0038] In the embodiment, the number of black tube wall 110 and transparent tube wall 120 is not limited, the ratio of the number of black tube wall 110 and transparent tube wall 120 can be 1:1, also can be 2:3 or 2:2, etc.
[0039] It should be understood that when the area ratio of black tube wall 110 and transparent tube wall 120 is 2:1, it can also be understood that two black tube walls 110 are provided, and one transparent tube wall 120 is provided, the area of a single black tube wall 110 is equal to the area of a single transparent tube wall 120, and the area ratio of the two black tube walls 110 and the transparent tube wall is 2:1.
[0040] Therefore, as long as the test tube body provided with black tube wall 110 and transparent tube wall 120 is within the protection scope of the present application.
[0041] The black tube wall 110 can be made by adding black pigment to the shaped raw material, or can be plated with a black coating or pasted with a black film on the outer wall of the black tube wall 110, or can be plated with a black coating or pasted with a black film on the inner wall of the black tube wall 110.
[0042] Exemplarily, one black tube wall 110 and one transparent tube wall 120 are provided, the black tube wall 110 and the transparent tube wall 120 are arranged along the axial direction or the circumferential direction of the test tube body 100, and the area ratio of the black tube wall 110 and the transparent tube wall 120 is 1:1. In another embodiment, two black tube walls 110 and two transparent tube walls 120 are provided, the black tube walls 110 and the transparent tube walls 120 are arranged along the axial direction or the circumferential direction of the test tube body 100, and the black tube walls 110 and the transparent tube walls 120 are alternately distributed, that is, the distribution rule is black tube wall 110, transparent tube wall 120, black tube wall 110, transparent tube wall 120.
[0043] In the operation process, first, a 5% concentration of phenol solution 200 needs to be prepared, when preparing, take pure phenol 25ml, then add distilled water to 500ml, shake hard, and then place in a 37℃ environment box for 24-48 hours, after complete dissolution, because the phenol solution 200 needs to avoid light, the prepared 5% concentration of phenol solution 200 is placed in a brown bottle and stored at room temperature.
[0044] Take 2-3ml of phenol solution, place it in the cerebrospinal fluid protein qualitative experiment detection test tube provided in the embodiment of the present application, then drop in 1-2 drops of cerebrospinal fluid, take the black tube wall 110 as the black background, and then observe the results.
[0045] If the sample is observed to be clear and transparent, not cloudy, it is negative. If the sample is observed to be slightly white fog, it is very weak positive, but this phenomenon needs to be observed with black tube wall 110 as the background. If the sample is positive, the sample can be divided into: (+) is gray cloud; (2+) is white turbidity; (3+) is white flocculent precipitate; (4+) is white clot according to the degree of positive.
[0046] The cerebrospinal fluid protein qualitative experimental detection test tube provided by the embodiment of the application can provide a black background for observing the sample, so that the sample is more obvious and the detection accuracy is improved. When observing the results, there is no need to find other black backgrounds, the test efficiency is improved, and the observer can observe through the transparent tube wall 120. The transparent tube wall 120 can reduce the interference on the observation results.
[0047] As shown in Figure 1 and Figure 2 , in one embodiment, the black tube wall 110 and the transparent tube wall 120 extend along the axis direction of the test tube body 100, and the black tube wall 110 and the transparent tube wall 120 are sequentially distributed along the circumference of the axis of the test tube body 100.
[0048] As shown in Figure 1 and Figure 2 , for example, one black tube wall 110 and one transparent tube wall 120 are provided; for example, the area ratio of the black tube wall 110 to the transparent tube wall 120 is 1:1. In another embodiment, the area ratio of the black tube wall 110 to the transparent tube wall 120 is 2:1. In another embodiment, the area ratio of the black tube wall 110 to the transparent tube wall 120 is 1:2.
[0049] As shown in Figure 4 and Figure 5 , for example, in another embodiment, the black tube wall 110 and the transparent tube wall 120 extend along the axis direction of the test tube body 100, two black tube walls 110 and two transparent tube walls 120 are provided; the black tube wall 110 and the transparent tube wall 120 are sequentially distributed around the circumference of the test tube body 100. In order to facilitate the understanding of the scheme, the two black tube walls 110 are respectively named as a first tube wall and a second tube wall, and the two transparent tube walls 120 are respectively named as a third tube wall and a fourth tube wall. The first tube wall, the third tube wall, the second tube wall and the fourth tube wall are sequentially distributed around the circumference of the test tube body 100. More than two black tube walls 110 and transparent tube walls 120 can be provided, and the test tube body can be rotated to use different black tube walls 110 as the observation background, so that the sample can be observed from multiple angles and the detection accuracy is improved.
[0050] As shown in Figure 3As shown, in one embodiment, the black tube wall 110 is arranged around the circumferential surface of the test tube body 100, and the transparent tube wall 120 is arranged around the circumferential surface of the test tube body 100. The black tube wall 110 and the transparent tube wall 120 are annular tube walls arranged around the axis of the test tube body 100. The transparent tube wall 120 and the black tube wall 110 are sequentially distributed along the axial direction of the test tube body 100, facilitating multi-angle observation of the sample and improving detection accuracy.
[0051] As shown, for example, one black tube wall 110 and one transparent tube wall 120 are provided. The area ratio of the black tube wall 110 to the transparent tube wall 120 is about 1:1. Figure 3
[0052] In another embodiment, the area ratio of the black tube wall 110 to the transparent tube wall 120 is about 1:1. Two black tube walls 110 and two transparent tube walls 120 are provided. For the convenience of understanding the scheme, the two black tube walls 110 are respectively named as a first annular tube wall and a second annular tube wall, and the two transparent tube walls 120 are respectively named as a third annular tube wall and a fourth annular tube wall. The third annular tube wall, the first annular tube wall, the fourth annular tube wall, and the second annular tube wall are sequentially arranged along a first direction or a second direction. The first direction is parallel to the test tube body 100 and points from the opening of the test tube body 100 to the bottom of the test tube body 100. The second direction is the reverse of the first direction.
[0053] In one embodiment, the cerebrospinal fluid protein qualitative test test tube further comprises a light shielding sticker. The light shielding sticker is attached to the outer circumferential surface of the transparent tube wall 120. For example, the number of light shielding stickers is matched with the number of transparent tube walls 120. When more black tube walls 110 are needed as black backgrounds for observing the sample, the light shielding stickers are attached to the transparent tube walls 120 to convert the transparent tube walls 120 into black backgrounds. Thus, the number of black backgrounds can be flexibly controlled according to the detection needs, improving the adaptability of the cerebrospinal fluid protein qualitative test test tube.
[0054] For example, the light shielding sticker is a black sticker. Of course, the light shielding sticker can also be provided in other colors, such as brown.
[0055] In one embodiment, the test tube body 100 stores a 5% concentration of phenol solution 200. This reduces the step of taking the phenol solution 200 from the storage container before the experiment, and there is no need to frequently open and close the phenol solution 200 storage container, simplifying the test steps and preventing poisoning damage caused by the volatilization of the phenol solution 200 into the respiratory tract of the human body. For example, 2ml to 3ml of 5% concentration of phenol solution 200 is provided in the test tube body 100.
[0056] In one embodiment, the cerebrospinal fluid protein qualitative test test tube further comprises a plug body installed at the opening of the test tube body 100 to prevent the phenol solution 200 from overflowing from the test tube body 100.
[0057] In the prior art, in addition to frequent access to the phenol solution 200, which endangers the human body by causing phenol solution 200 vapor, the harm of the prior art also lies in the handling of the 5% concentration phenol solution 200 after the experimental operation is completed. Directly pouring the 5% concentration phenol solution 200 into the medical waste water treatment system will be accompanied by volatilization, and the water resource will also be wasted by the water flushing of the pouring pipeline.
[0058] The 5% concentration phenol solution 200 provided in the test tube body 100 will not cause a large amount of volatilization or leakage. The opening of the test tube body 100 is closed by the plug body, thereby ensuring that the sample in the test tube body 100 will not overflow or volatilize in the closed lid state.
[0059] In a second aspect, the embodiments of the present application provide a cerebrospinal fluid protein qualitative test reagent kit, which comprises a storage member and the cerebrospinal fluid protein qualitative test test tube of any of the above embodiments.
[0060] The storage member has a storage space, and the storage member is made of light-proof material. The cerebrospinal fluid protein qualitative test test tube is arranged in the storage space. The 5% concentration phenol solution 200 in the test tube body 100 can be further prevented from being irradiated by light by the storage member, thereby ensuring the quality of the phenol solution 200 and the accuracy of the experimental results.
[0061] In one embodiment, the cerebrospinal fluid protein qualitative test reagent kit further comprises a sampling member arranged in the storage space, and the sampling member is used to suck the cerebrospinal fluid sample for detection and add it to the test tube body 100.
[0062] Exemplarily, the sampling member is a dropper. In another embodiment, the sampling member is a straw.
[0063] In the process of using the cerebrospinal fluid protein qualitative test reagent kit provided by the embodiments of the present application, the operator can only open the storage member to take out the test tube body 100 in the sample detection operation. After opening the plug body of the test tube body 100, the disposable sampling member in the storage member is used to draw the cerebrospinal fluid sample and drop it into the test tube body 100, and the detection operation can be completed. The test tube body 100 provides a black background required for observing the results. After the experimental operation is completed, the plug body can be re-covered on the opening of the test tube body 100, thereby ensuring that the 5% phenol solution 200 after use will not volatilize and pollute the environment.
[0064] In one embodiment, the storage member is a box body structure, and the inner wall of the box body structure is black.
[0065] In one embodiment, the storage member of the above-mentioned embodiment of the box structure can be replaced by the following technical solution:
[0066] The storage member is a packaging bag, and an inner wall of the packaging bag is black.
[0067] In all examples shown and described herein, any specific values should be interpreted as merely exemplary and not limiting, and thus other examples of the example embodiments can have different values.
[0068] It should be noted that similar reference numbers and letters refer to similar items in the following drawings, and thus, once an item is defined in one drawing, it need not be further defined and explained in subsequent drawings.
[0069] The above-mentioned embodiments only express several implementation manners of the utility model, and the description is more specific and detailed, but it should not be understood as the limitation of the scope of the utility model. It should be pointed out that for ordinary skilled in the art, several modifications and improvements can be made without departing from the concept of the utility model, and these all belong to the protection scope of the utility model.
Claims
1. A test tube for qualitative analysis of cerebrospinal fluid proteins, characterized in that, include: The test tube body (100) has two or more black tube walls (110) and two or more transparent tube walls (120) that are alternately distributed.
2. The cerebrospinal fluid protein qualitative test tube according to claim 1, characterized in that, The black tube wall (110) and the transparent tube wall (120) extend along the axial direction of the test tube body (100), and the black tube wall (110) and the transparent tube wall (120) are distributed sequentially along the circumferential direction of the axial direction of the test tube body (100).
3. The cerebrospinal fluid protein qualitative test tube according to claim 1, characterized in that, The black tube wall (110) extends around the circumference of the test tube body (100), and the transparent tube wall (120) extends around the circumference of the test tube body (100). The transparent tube wall (120) and the black tube wall (110) are distributed sequentially along the axial direction of the test tube body (100).
4. The cerebrospinal fluid protein qualitative test tube according to claim 2 or 3, characterized in that, Also includes: A light-blocking sticker is affixed to the outer circumferential surface of the transparent tube wall (120).
5. The cerebrospinal fluid protein qualitative test tube according to claim 4, characterized in that, The test tube body (100) contains a phenol solution (200) with a concentration of 5%.
6. The cerebrospinal fluid protein qualitative test tube according to claim 5, characterized in that, Also includes: A stopper is installed at the opening of the test tube body (100).
7. A reagent kit for qualitative analysis of cerebrospinal fluid proteins, characterized in that, include: A storage device having storage space, the storage device being made of a light-shielding material; The cerebrospinal fluid protein qualitative test tube as described in any one of claims 1 to 6, wherein the cerebrospinal fluid protein qualitative test tube is disposed within the storage space.
8. The cerebrospinal fluid protein qualitative test reagent kit according to claim 7, characterized in that, Also includes: A sampling device is disposed within the storage space and is used to aspirate cerebrospinal fluid samples for testing and add them to the test tube body (100).
9. The cerebrospinal fluid protein qualitative test reagent kit according to claim 7, characterized in that, The storage device is a box structure, and the inner wall of the box structure is black.
10. The cerebrospinal fluid protein qualitative test reagent kit according to claim 7, characterized in that, The storage component is a packaging bag, and the inner wall of the packaging bag is black.