Pulsation vacuum sterilizer for pharmaceutical production

Abstract

The utility model discloses a pulsating vacuum sterilizer for pharmaceutical production, which belongs to the field of pharmaceutical sterilization equipment and is characterized in that a waste gas treatment tank is arranged at the inner bottom of an equipment support frame, a detachable sealing cover is mounted at the upper end of the waste gas treatment tank, a getter pump is mounted at the upper end of the detachable sealing cover, and a connecting nozzle is mounted at the upper end of the getter pump; the connecting nozzle is connected with the vacuum sterilization tank through a pipeline to realize gas flow; a filtering inner cylinder is arranged in the waste gas treatment tank, and a first filtering layer and a second filtering layer are sequentially arranged in the filtering inner cylinder from top to bottom. Harmful substances are filtered through waste gas treatment and filtering design, and pollution is reduced. A liquid outlet and a valve are designed to control waste liquid discharge, and the production environment is kept clean. The design of the detachable sealing cover and the filtering inner cylinder facilitates maintenance and cleaning of equipment, and long-term stable operation is guaranteed. The filter mechanism is convenient to replace, continuous filter effect is ensured, the equipment is kept in a good working state for a long time, and continuous sterile guarantee is provided for pharmaceutical production.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical sterilization equipment, and in particular to a pulsed vacuum sterilizer for pharmaceutical production. Background Technology

[0002] A pulsed vacuum sterilizer is a sterilization device used in pharmaceutical production. It utilizes pulsed vacuum technology to improve sterilization efficiency and effectiveness. Through multiple vacuuming and steam filling processes, the device ensures no air residue remains within the sterilization chamber, thus achieving effective sterilization of heat-sensitive items. Pulsed vacuum sterilizers are particularly suitable for pharmaceuticals, plastic containers, and rubber products that cannot withstand high-temperature, high-pressure sterilization. It provides a uniform temperature and pressure distribution, ensuring thorough sterilization while minimizing damage to the items. In the pharmaceutical industry, pulsed vacuum sterilizers are one of the most important pieces of equipment for ensuring product quality and safety.

[0003] Currently, the pulsed vacuum sterilizers used in pharmaceutical production require the extraction of air and liquid from the tank during operation. The waste gas and waste liquid generated during sterilization must be properly stored and treated to meet environmental emission standards. However, there are currently some shortcomings in waste gas emissions. These shortcomings may include inadequate emission treatment technologies and imperfect monitoring and control systems. Utility Model Content

[0004] The main objective of this invention is to provide a pulsed vacuum sterilizer for pharmaceutical production, which can effectively solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the technical solution adopted by this utility model is as follows:

[0006] A pulsed vacuum sterilizer for pharmaceutical production includes an equipment support frame, a control cabinet, connecting pipes, a cooling device, and a vacuum sterilization tank. The control cabinet, cooling device, and vacuum sterilization tank are mounted on the equipment support frame and connected to each other via connecting pipes. The equipment enables vacuum sterilization operations in pharmaceutical manufacturing.

[0007] The equipment support frame has an exhaust gas treatment tank at its inner bottom and a detachable sealing cover at its upper end. An air suction pump is installed at the upper end of the detachable sealing cover, and a connecting nozzle is installed at the upper end of the air suction pump. The connecting nozzle is connected to the vacuum sterilization tank through a pipe to achieve gas flow.

[0008] The waste gas treatment tank is equipped with a filter inner cylinder. The filter inner cylinder has a first filter layer and a second filter layer arranged from top to bottom. The waste gas is filtered through the first filter layer and the second filter layer. The lower end of the waste gas treatment tank is equipped with a drain port to discharge the waste liquid inside the waste gas treatment tank.

[0009] As an optional solution of this application, the filter inner cylinder is fixed to the inner end face of the detachable sealing cover by bolts, and filter screens are installed at the upper and lower ends of the filter inner cylinder.

[0010] As an optional solution of this application, the exhaust gas treatment tank is installed at the inner bottom of the equipment support frame by means of brackets, bolts and nuts, and the exhaust gas treatment tank is connected to a detachable sealing cover by means of bolts, nuts and gaskets, and a sealing ring is provided at the connection between the detachable sealing cover and the exhaust gas treatment tank;

[0011] As an optional solution of this application, the air pump is fixed to the outer end face of the detachable sealing cover by bolts, the air outlet of the air pump is facing the inner filter cylinder, the air pump and the connecting nozzle are connected by threads, and both ends of the connecting nozzle are connected with sealing rings. The connecting nozzle and the pipeline of the vacuum sterilization tank are fixed by connecting flanges, bolts and nuts.

[0012] As an optional solution of this application, the first filter layer and the second filter layer are an inorganic non-woven fiber filter layer and an activated carbon filter layer, and the inorganic non-woven fiber filter layer and the activated carbon filter layer are fixed in the filter inner cylinder by a filter screen.

[0013] As an optional solution in this application, the drain port is sealed and fixed at the bottom of the waste gas treatment tank, and a valve is installed on the drain port.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] By employing a vacuum and heating process in a pulsed vacuum sterilizer, we can ensure that pharmaceutical materials are thoroughly sterilized. This process is crucial for meeting the stringent requirements for a sterile environment in pharmaceutical manufacturing. Vacuum technology effectively removes air from the container, while heating kills any potential microorganisms, thus ensuring the sterility of the materials.

[0016] During the sterilization process, the design of the exhaust gas treatment tank and filter inner cylinder plays a crucial role. These designs effectively filter the exhaust gases generated during sterilization, removing harmful substances and reducing environmental pollution. Through this filtration and sealing design, we can ensure that exhaust gases and waste liquids are properly treated, avoiding harm to the health of operators and the environment.

[0017] The design of the drain outlet and valves has also been carefully considered to facilitate the control of waste liquid discharge. This design ensures the cleanliness and hygiene of the production process, preventing waste liquid from polluting the production environment. Furthermore, the design of the detachable sealing cover and filter inner cylinder makes equipment maintenance and cleaning very convenient, thereby ensuring long-term stable operation of the equipment.

[0018] The designers also fully considered ease of operation during the filter replacement process. The entire replacement process is rationally designed, allowing operators to quickly and easily replace the filter layer, thus ensuring continuous filtration effectiveness. Furthermore, the equipment design also prioritizes ease of cleaning and maintenance, ensuring the equipment maintains optimal working condition during long-term use, thereby providing continuous aseptic protection for pharmaceutical production. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0020] Figure 2 This is a side view of the overall structure of this utility model;

[0021] Figure 3 The illustration shows the waste gas treatment tank, air intake pump, and detachable sealing cover of this utility model.

[0022] Figure 4 This is a cross-sectional view of the exhaust gas treatment tank, air pump, detachable sealing cover, and filter inner cylinder of the present invention.

[0023] In the diagram: 1. Equipment support frame; 2. Control cabinet; 3. Connecting pipes; 4. Cooling device; 5. Vacuum sterilization tank; 6. Waste gas treatment tank; 7. Detachable sealing cover; 8. Suction pump; 9. Connecting nozzle; 10. Filter inner cylinder; 11. First filter layer; 12. Second filter layer; 13. Drain outlet. Detailed Implementation

[0024] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.

[0025] like Figure 1 - Figure 4 As shown, a pulsed vacuum sterilizer for pharmaceutical production includes a support frame 1, a control cabinet 2, connecting pipes 3, a cooling device 4, and a vacuum sterilization tank 5. These main components are all mounted on the support frame 1 and interconnected via the connecting pipes 3, enabling the entire device to work collaboratively to complete the vacuum sterilization operation required in the pharmaceutical manufacturing process.

[0026] The inner bottom of the equipment support frame 1 is specially designed with an exhaust gas treatment tank 6 to ensure that the exhaust gas generated during sterilization is properly treated. A removable sealing cover 7 is installed at the top of the exhaust gas treatment tank 6 for easy maintenance and cleaning. To further ensure the sealing performance of the exhaust gas treatment tank 6, an air suction pump 8 is also installed at the top of the removable sealing cover 7, which draws the exhaust gas out of the treatment tank. A connecting nozzle 9 is connected to the top of the air suction pump 8, and the connecting nozzle 9 is connected to the vacuum sterilization tank 5 through a pipe, thus forming a complete gas flow path.

[0027] The exhaust gas treatment tank 6 is internally designed with a filter inner cylinder 10. Inside the filter inner cylinder 10, from top to bottom, are arranged a first filter layer 11 and a second filter layer 12. These two filter layers consist of an inorganic non-woven fiber filter layer and an activated carbon filter layer, respectively. Together, they effectively filter out harmful substances in the exhaust gas. To ensure the stability and filtration effect of the filter layers, the filter inner cylinder 10 is bolted to the inner end face of the detachable sealing cover 7, and filter screens are installed at both the upper and lower ends of the filter inner cylinder 10 to prevent the filter material from falling off.

[0028] The exhaust gas treatment tank 6 is installed at the inner bottom of the equipment support frame 1 via brackets, bolts, and nuts. The exhaust gas treatment tank 6 is tightly connected to the detachable sealing cover 7 via bolts, nuts, and gaskets. To further enhance the sealing performance of the connection, a sealing ring is specially designed at the connection between the detachable sealing cover 7 and the exhaust gas treatment tank 6. The suction pump 8 is fixed to the outer end face of the detachable sealing cover 7 via bolts, with its outlet facing the inner filter cylinder 10 to ensure that exhaust gas can be effectively drawn in and filtered. The suction pump 8 is threadedly connected to the connecting nozzle 9, and both ends of the connecting nozzle 9 are connected with sealing rings to ensure the sealing of the connection. The pipe connection between the connecting nozzle 9 and the vacuum sterilization tank 5 is fixed with connecting flanges, bolts, and nuts to ensure the stable operation of the entire system.

[0029] To facilitate the discharge of waste liquid from inside the waste gas treatment tank 6, the drain port 13 is sealed and fixed to the bottom of the waste gas treatment tank 6, and a valve is installed on the drain port 13 to control the discharge of waste liquid. Through this design, waste gas and waste liquid in pharmaceutical production are effectively treated, ensuring the environmental protection and safety of the production process.

[0030] Operating Procedure: Ensure the power supply to the pulsed vacuum sterilizer is connected and check that all connecting pipes 3 are correctly installed and leak-free. Set the required sterilization parameters, such as temperature, pressure, and time, on the control cabinet 2. Place the materials to be sterilized into the vacuum sterilization tank 5. Start the sterilization program on the control cabinet 2; the equipment will begin vacuuming and heating. The equipment will input heated steam into the vacuum sterilization tank 5 through connecting pipes 3 for sterilization. After sterilization, the cooling device 4 will activate to reduce the temperature inside the sterilization tank to a safe level. The exhaust gas from the sterilization tank will enter the exhaust gas treatment tank 6 through connecting pipes 3. The exhaust gas will be purified in the exhaust gas treatment tank 6 by passing through two layers of filters in the inner filter cylinder 10. Waste liquid generated during the sterilization process will be discharged through the drain port 13, with the discharge rate controlled by a valve. Once the sterilization process is confirmed to be complete, the equipment will stop operating, and the sterilized materials will be removed.

[0031] Filter Replacement Procedure: Turn off the power to the equipment and ensure all steam and vacuum have been completely released. Open the drain valve 13 at the bottom of the exhaust gas treatment tank 6 to drain the internal waste liquid. Loosen and remove the bolts, nuts, and gaskets at the bottom of the exhaust gas treatment tank 6 to separate the exhaust gas treatment tank 6 from the removable sealing cover 7. Remove the removable sealing cover 7 to expose the inner filter cylinder 10. Loosen the bolts on the inner filter cylinder 10 and remove it. Replace the first filter layer 11 and the second filter layer 12, ensuring the new filter layers are correctly installed and securely fixed. Reinstall the inner filter cylinder 10 onto the removable sealing cover 7 and tighten the bolts. Reconnect the exhaust gas treatment tank 6 to the removable sealing cover 7, ensuring the sealing rings at the connection points are intact. Tighten all bolts, nuts, and gaskets to ensure a good seal at the connection points. After replacement, restart the equipment and test to ensure the filter mechanism is functioning correctly.

[0032] Cleaning Process: Turn off the power to the equipment and ensure all steam and vacuum have been completely released. Open the drain valve 13 at the bottom of the exhaust gas treatment tank 6 to drain the internal waste liquid. Loosen and remove the bolts, nuts, and gaskets at the bottom of the exhaust gas treatment tank 6 to separate the exhaust gas treatment tank 6 from the removable sealing cover 7. Remove the removable sealing cover 7 to expose the filter inner cylinder 10. Remove the filter inner cylinder 10 and clean the filter screen and filter layer with appropriate detergent and water. Clean the inner and outer surfaces of the filter inner cylinder 10 to ensure no residue remains. Clean the inside of the exhaust gas treatment tank 6 with appropriate detergent and water to ensure no residue remains. After cleaning, thoroughly dry all parts. Reinstall the filter inner cylinder 10 onto the removable sealing cover 7 and tighten the bolts. Reconnect the exhaust gas treatment tank 6 to the removable sealing cover 7, ensuring the sealing rings at the connection points are intact. Tighten all bolts, nuts, and gaskets to ensure good sealing performance at the connection points. After cleaning, restart the equipment for testing to ensure proper operation.

[0033] It should be noted that, in this document, relational terms such as first and second (number one, number two), etc., are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Unless otherwise specified, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes the element.

[0034] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A pulsed vacuum sterilizer for pharmaceutical production, comprising an equipment support frame (1), a control cabinet (2), connecting pipes (3), a cooling device (4), and a vacuum sterilization tank (5), wherein the control cabinet (2), the cooling device (4), and the vacuum sterilization tank (5) are mounted on the equipment support frame (1) and connected by connecting pipes (3), thereby enabling vacuum sterilization operations in pharmaceutical manufacturing, characterized in that: The equipment support frame (1) has an exhaust gas treatment tank (6) at its inner bottom, and a detachable sealing cover (7) is installed at the upper end of the exhaust gas treatment tank (6). An air suction pump (8) is installed at the upper end of the detachable sealing cover (7), and a connecting nozzle (9) is installed at the upper end of the air suction pump (8). The connecting nozzle (9) is connected to the vacuum sterilization tank (5) through a pipe to achieve gas flow. The waste gas treatment tank (6) is equipped with a filter inner cylinder (10). The filter inner cylinder (10) is provided with a first filter layer (11) and a second filter layer (12) from top to bottom. The waste gas is filtered through the first filter layer (11) and the second filter layer (12). The waste gas treatment tank (6) is equipped with a drain port (13) at the lower end. The waste liquid inside the waste gas treatment tank (6) is discharged through the drain port (13).

2. The pulsed vacuum sterilizer for pharmaceutical production according to claim 1, characterized in that: The filter inner cylinder (10) is fixed to the inner end face of the detachable sealing cover (7) by bolts, and filter screens are installed at the upper and lower ends of the filter inner cylinder (10).

3. The pulsed vacuum sterilizer for pharmaceutical production according to claim 2, characterized in that: The waste gas treatment tank (6) is installed at the bottom of the equipment support frame (1) by means of brackets, bolts and nuts, and the waste gas treatment tank (6) is connected to a detachable sealing cover (7) by means of bolts, nuts and gaskets. A sealing ring is provided at the connection between the detachable sealing cover (7) and the waste gas treatment tank (6).

4. A pulsed vacuum sterilizer for pharmaceutical production according to claim 3, characterized in that: The suction pump (8) is fixed to the outer end face of the detachable sealing cover (7) by bolts. The air outlet of the suction pump (8) is directly facing the filter inner cylinder (10). The suction pump (8) and the connecting nozzle (9) are connected by threads. Both ends of the connecting nozzle (9) are connected with sealing rings. The connecting nozzle (9) and the pipe of the vacuum sterilizer (5) are fixed by connecting flanges, bolts and nuts.

5. A pulsed vacuum sterilizer for pharmaceutical production according to claim 4, characterized in that: The first filter layer (11) and the second filter layer (12) are inorganic non-woven fiber filter layers and activated carbon filter layers, respectively, and the inorganic non-woven fiber filter layers and activated carbon filter layers are fixed in the filter inner cylinder (10) by a filter screen.

6. A pulsed vacuum sterilizer for pharmaceutical production according to claim 5, characterized in that: The drain port (13) is sealed and fixed at the bottom of the waste gas treatment tank (6), and a valve is installed on the drain port (13).

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