Hair follicle cell culture sample collecting device for autologous hair follicle hair growth

Abstract

The utility model relates to the technical field of hair follicle sample collection, in particular to a hair follicle cell culture sample collection device for autologous hair follicle hair growth, which comprises a shell and a cover body, a switching mechanism is arranged on the inner wall of the shell, and the switching mechanism comprises a cylindrical block, a connecting rod, a spring I and a positioning block. According to the utility model, the closing mechanism is arranged, the collecting groove in the collecting frame effectively collects and stores cell samples, at the moment, the tiny through hole of the conical groove is blocked, the air pressure in the collecting groove is increased, and the light connecting block is extruded by high pressure, so that the light connecting block is propped against the pull rope, and the pull rope drives the limiting block to move upwards; at the moment, a limiting block is not clamped with a positioning groove in a sealing block any more, so that the bottom of the collecting groove is blocked and sealed by the sealing block under the action of a fourth spring, external high-pressure air is prevented from continuously entering the collecting groove, damage to a cell sample caused by too high air pressure is avoided, and the collecting efficiency and the sample quality are improved.

Description

Technical Field

[0001] This utility model relates to the field of hair follicle sample collection technology, specifically a device for collecting autologous hair follicle cell culture samples. Background Technology

[0002] Hair follicle stem cells are a type of stem cell found in the ridge of the outer root sheath of human hair follicles. Hair follicle stem cells are adult stem cells that remain dormant in vivo but exhibit remarkable proliferative capacity when cultured in vitro. Studies have found that hair follicle stem cells possess multi-directional differentiation potential, capable of differentiating into the epidermis, hair follicles, and sebaceous glands, and participating in the skin wound healing process.

[0003] Chinese patent CN215209429U discloses a "sample collection device for hair follicle stem cell culture". By setting up a collection tube, it effectively provides multiple storage spaces for samples, making it easier for the device to collect more samples, improving the device's capacity, shortening the sample recovery cycle, and enabling the collection of a large number of samples within a specific time. By setting up a micro air pump, it achieves automatic adsorption collection of samples, avoiding the complicated process of manual collection and improving collection efficiency. By setting up small holes, it prevents samples from falling out of the storage tube while effectively ensuring the connection between the storage tube and the external air pressure, ensuring the normal use and operation of the device.

[0004] When manually pressing the button to operate the mini air pump, it is impossible to accurately determine the required air volume or duration, resulting in the mini air pump working continuously for too long. This causes excessive external airflow to enter the storage tube, leading to excessively high internal air pressure, which in turn causes compressive damage to the air sac cells, resulting in cell structure destruction.

[0005] In view of this, we propose a device for collecting autologous hair follicle cell culture samples. Utility Model Content

[0006] The purpose of this invention is to provide a device for collecting autologous hair follicle cell culture samples. This device solves the problem that manual control of a micro air pump can easily lead to excessive air extraction, causing excessively high air pressure in the storage tube, which in turn can compress and damage the structure of the air follicle cells.

[0007] To achieve the above objectives, this utility model provides the following technical solution:

[0008] A device for collecting autologous hair follicle cell culture samples includes a shell and a cover. A conversion mechanism is provided on the inner wall of the shell. The conversion mechanism includes a cylindrical block, a connecting rod, a first spring, and a positioning block. A closing mechanism is provided on the inner wall of the cylindrical block. The closing mechanism includes a second spring, one end of which is fixedly connected to the inner wall of the cylindrical block, and the other end of which is fixedly connected to a positioning pin. A collection frame is inserted into the inner wall of the cylindrical block. The top of the collection frame has an arc-shaped handle groove. The inner wall of the collection frame has a collection groove and a conical groove. The top of the conical groove has a micro-opening. A small through hole is provided. One end of a pull rope is fixedly connected to the inner wall of the collection frame. The other end of the pull rope is fixedly connected to a limit block. One end of a spring three is fixedly connected to the top of the limit block. The other end of the spring three is fixedly connected to the inner wall of the collection frame. One end of a spring four is fixedly connected to the inner wall of the collection frame. The other end of the spring four is fixedly connected to a closing block. A telescopic rod is fixedly connected to the outer wall of the closing block. The outer wall of the telescopic rod is fixedly connected to the inner wall of the collection frame. A positioning groove is provided at the top of the closing block. One end of a spring five is fixedly connected to the inner wall of the collection frame. The other end of the spring five is fixedly connected to a lightweight connecting block.

[0009] Preferably, the bottom of the cover is threaded to the housing, the cover includes a top connector, the top of the top connector has a through hole, an annular block is fixedly connected to the inner wall of the top connector, a one-way valve is fixedly connected to the inner wall of the annular block, and a ball bearing is provided at the bottom of the top connector.

[0010] Preferably, the cylindrical block is rotatably connected to the inner wall of the shell, a connecting rod is fixedly connected to the outer wall of the cylindrical block, one end of a spring is fixedly connected to the inner wall of the shell, and a positioning block is fixedly connected to the other end of the spring. The bottom of the positioning block is a semi-circular groove, and six positioning blocks are provided, which are arranged in a circumferential array.

[0011] Preferably, a probe is fixedly connected to the inner wall of the housing, and a cutting part is fixedly connected to the bottom of the probe.

[0012] Preferably, the probe is equipped with a miniature air pump, which is used to provide suction.

[0013] Preferably, the head of the positioning pin is hemispherical, and the outer wall of the collection frame is provided with a hemispherical groove.

[0014] Preferably, the outer wall of the lightweight connecting block is piston-connected to the inner wall of the collecting frame, and the lightweight connecting block is L-shaped.

[0015] By employing the above technical solution, this utility model provides a device for collecting autologous hair follicle cell culture samples for hair follicle regeneration. It possesses at least the following beneficial effects:

[0016] (1) This utility model has a closed mechanism. The collection slot in the collection frame can effectively collect and store cell samples. At this time, the tiny through hole of the conical slot is blocked. At this time, the air pressure in the collection slot increases. The high pressure squeezes the lightweight connecting block, causing the lightweight connecting block to abut against the pull rope. The pull rope drives the limiting block to move upward. At this time, the limiting block no longer engages with the positioning slot on the closed block. Under the action of the spring, the closed block blocks and seals the bottom of the collection slot, preventing the high-pressure air from the outside from continuing to enter the collection slot and preventing excessive air pressure from damaging the cell samples. This improves the collection efficiency and sample quality.

[0017] (2) This utility model incorporates a conversion mechanism. After collection, by rotating and adjusting the cylindrical block, the operator can adjust the position of the connecting rod as needed, thereby engaging with collection frames at different positions. The operator can select and rotate different collection frames to collect cell samples as required. The positioning block engages with the connecting rod through a semi-circular groove, ensuring the stability of the positioning block and increasing the flexibility and accuracy of the collection process. Attached Figure Description

[0018] The accompanying drawings, which are included to provide a further understanding of the present invention, form part of this application:

[0019] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0020] Figure 2 This is a cross-sectional structural diagram of the top connector in this utility model;

[0021] Figure 3 This is a cross-sectional structural diagram of the shell in this utility model;

[0022] Figure 4 This is a schematic diagram of the conversion mechanism in this utility model;

[0023] Figure 5 This is a cross-sectional structural diagram of the collection frame in this utility model;

[0024] Figure 6 In this utility model Figure 5 Enlarged structural diagram at point A in the diagram;

[0025] Figure 7 This is a schematic diagram of the limiting block in this utility model.

[0026] In the diagram: 1. Shell; 2. Cover; 21. Top connector; 22. Annular block; 23. One-way valve; 24. Ball bearing; 3. Probe; 4. Cutting part; 5. Miniature air pump; 6. Conversion mechanism; 61. Cylindrical block; 62. Connecting rod; 63. Spring 1; 64. Positioning block; 7. Closing mechanism; 71. Spring 2; 72. Positioning pin; 73. Collection frame; 74. Arc-shaped handle groove; 75. Collection groove; 76. Conical groove; 77. Pull rope; 78. Limiting block; 79. Spring 3; 710. Spring 4; 711. Closing block; 712. Telescopic rod; 713. Positioning groove; 714. Spring 5; 715. Lightweight connecting block. Detailed Implementation

[0027] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0028] Please see Figures 1-7As shown, this utility model provides a technical solution: a hair follicle cell culture sample collection device for autologous hair follicle growth, including a shell 1 and a cover 2. A conversion mechanism 6 is provided on the inner wall of the shell 1. The conversion mechanism 6 includes a cylindrical block 61, a connecting rod 62, a spring 63, and a positioning block 64. A closing mechanism 7 is provided on the inner wall of the cylindrical block 61. The closing mechanism 7 includes a spring 71, one end of which is fixedly connected to the inner wall of the cylindrical block 61, and the other end of which is fixedly connected to a positioning pin 72. A collection frame 73 is inserted into the inner wall of the cylindrical block 61. An arc-shaped handle groove 74 is provided on the top of the collection frame 73, making it easier for operators to pick up, move, or adjust the collection frame 73, increasing the convenience and comfort of operation. A collection groove 75 and a conical groove 75 are provided on the inner wall of the collection frame 73. 6. A small through hole is provided at the top of the conical groove 76 to control the internal airflow and the flow of the channel. One end of the pull rope 77 is fixedly connected to the inner wall of the collection frame 73. The other end of the pull rope 77 is fixedly connected to the limit block 78. One end of the spring three 79 is fixedly connected to the top of the limit block 78. The other end of the spring three 79 is fixedly connected to the inner wall of the collection frame 73. One end of the spring four 710 is fixedly connected to the inner wall of the collection frame 73. The other end of the spring four 710 is fixedly connected to the sealing block 711. The outer wall of the sealing block 711 is fixedly connected to the telescopic rod 712. The outer wall of the telescopic rod 712 is fixedly connected to the inner wall of the collection frame 73. A positioning groove 713 is provided at the top of the sealing block 711. One end of the spring five 714 is fixedly connected to the inner wall of the collection frame 73. The other end of the spring five 714 is fixedly connected to the lightweight connecting block 715.

[0029] The bottom of the cover 2 is threaded to the housing 1. The cover 2 includes a top connector 21. The top of the top connector 21 has a through hole for airflow transmission. Specifically, it provides an airflow path for the micro air pump 5. An annular block 22 is fixedly connected to the inner wall of the top connector 21. A one-way valve 23 is fixedly connected to the inner wall of the annular block 22 to ensure that the airflow can only flow in one direction and prevent the airflow from flowing in reverse. This helps the micro air pump 5 to operate normally and ensures the effective transmission of airflow during the collection process. At the same time, it avoids backflow of external airflow or unstable air pressure, thereby maintaining the stability of airflow and pressure during the sample collection process. A ball bearing 24 is provided at the bottom of the top connector 21. When the ball bearing 24 abuts against the cylindrical block 61, the cylindrical block 61 can rotate more smoothly.

[0030] A cylindrical block 61 is rotatably connected to the inner wall of the housing 1. A connecting rod 62 is fixedly connected to the outer wall of the cylindrical block 61. One end of a spring 63 is fixedly connected to the inner wall of the housing 1, and the other end of the spring 63 is fixedly connected to a positioning block 64. The bottom of the positioning block 64 is a semi-circular groove. Six positioning blocks 64 are arranged in a circumferential array. The semi-circular groove of the positioning block 64 engages with the outer wall of the connecting rod 62. Rotating the connecting rod 62 causes the cylindrical block 61 to rotate. When the connecting rod 62 engages with the positioning blocks 64 at different positions, the rotation angle of the cylindrical block 61 can be adjusted and locked, thereby controlling the arrangement of the collection tank 75. This ensures that the usage sequence or position adjustment of each collection device can be achieved during the collection process. This structure helps to improve the flexibility and efficiency of collection and can be used to... To precisely control the collection of cell samples, a probe 3 is fixedly connected to the inner wall of the housing 1, and a cutting part 4 is fixedly connected to the bottom of the probe 3. The combination of the probe 3 and the cutting part 4 is used to directly act on the target area such as hair follicles or tissues during the collection process. The cutting part 4 can effectively cut or penetrate the scalp layer or the tissue around the hair follicles through its sharp structure, so as to successfully obtain cell samples. A micro air pump 5 is provided on the probe 3 to provide suction to help draw in the cut cell samples and guide them to the collection tank 75. The micro air pump 5 can effectively attract cell samples into the probe 3 by generating negative pressure, thereby avoiding sample loss or damage. This design can improve the collection efficiency and ensure that cell samples are safely and quickly collected and stored during the collection process.

[0031] The head of the positioning pin 72 is hemispherical, and the outer wall of the collection frame 73 has a hemispherical groove. This is mainly used to ensure the precise docking and positioning between the positioning pin 72 and the collection frame 73. The hemispherical shape makes it easier for the positioning pin 72 to cooperate with the hemispherical groove on the collection frame 73, thereby ensuring that the collection frame 73 is accurately positioned inside the device and is not easily shifted. This design enhances the stability of the device and ensures that the collection frame 73 will not fall off or shift due to operation or movement during the collection process, thereby improving the accuracy and reliability of the sampling process. The outer wall of the lightweight connecting block 715 is piston-connected to the inner wall of the collection frame 73. The lightweight connecting block 715 is L-shaped. When the lightweight connecting block 715 is under pressure, it will squeeze the spring 714, causing the lightweight connecting block 715 to press against the pull rope 77 to the left, causing the pull rope 77 to bend.

[0032] In use, the autologous hair follicle cell culture sample collection device of this invention involves inserting the probe 3 and the cutting part 4 according to the target area, such as the scalp or hair follicles. The cutting part 4 cuts or penetrates the target area with its sharp structure. Then, the micro air pump 5 is turned on to conduct negative pressure into the probe, helping to aspirate the cut cell samples. After entering the probe 3, the cell samples are guided to the collection groove 75 by airflow. Airflow is controlled by the conical groove 76 and micro-through holes to ensure that the cell samples are not lost. The collection groove 75 in the collection frame 73 effectively collects the cell samples. During storage, the tiny through-holes in the conical groove 76 are blocked, increasing the air pressure inside the collection tank 75. This high pressure compresses the lightweight connecting block 715, causing it to contact the pull rope 77. The pull rope 77 then moves the limiting block 78 upward. At this point, the limiting block 78 no longer engages with the positioning groove 713 on the sealing block 711. Under the action of the spring 710, the sealing block 711 blocks and seals the bottom of the collection tank 75, preventing high-pressure air from entering the collection tank 75 and avoiding damage to the cell samples due to excessive air pressure. This improves collection efficiency and sample quality.

[0033] After collection, by rotating and adjusting the cylindrical block 61, the operator can adjust the position of the connecting rod 62 as needed, thereby engaging with the collection frame 73 at different positions. The operator can select and rotate different collection frames 73 as needed to collect cell samples. The positioning block 64 engages with the connecting rod 62 through a semi-circular groove, ensuring the stability of the positioning block and increasing the flexibility and accuracy of the collection process.

[0034] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0035] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A device for collecting autologous hair follicle cell culture samples, comprising a shell (1) and a cover (2), characterized in that: A conversion mechanism (6) is provided on the inner wall of the housing (1). The conversion mechanism (6) includes a cylindrical block (61), a connecting rod (62), a spring (63), and a positioning block (64). A closing mechanism (7) is provided on the inner wall of the cylindrical block (61). The closing mechanism (7) includes: A second spring (71) is fixedly connected at one end to the inner wall of a cylindrical block (61), and a positioning pin (72) is fixedly connected at the other end of the second spring (71). A collection frame (73) is inserted into the inner wall of the cylindrical block (61). An arc-shaped handle groove (74) is provided at the top of the collection frame (73). A collection groove (75) is provided on the inner wall of the collection frame (73). A conical groove (76) is provided on the inner wall of the collection frame (73). A small through hole is opened at the top of the conical groove (76). One end of a pull rope (77) is fixedly connected to the inner wall of the collection frame (73). A limit block (78) is fixedly connected at the other end of the pull rope (77). The top of the limit block (78) is... One end of spring three (79) is fixedly connected, and the other end of spring three (79) is fixedly connected to the inner wall of collection frame (73). One end of spring four (710) is fixedly connected to the inner wall of collection frame (73), and the other end of spring four (710) is fixedly connected to a closing block (711). The outer wall of the closing block (711) is fixedly connected to a telescopic rod (712), and the outer wall of the telescopic rod (712) is fixedly connected to the inner wall of collection frame (73). A positioning groove (713) is provided on the top of the closing block (711). One end of spring five (714) is fixedly connected to the inner wall of collection frame (73), and the other end of spring five (714) is fixedly connected to a lightweight connecting block (715).

2. The device for collecting autologous hair follicle cell culture samples according to claim 1, characterized in that: The bottom of the cover (2) is threaded to the shell (1). The cover (2) includes a top connector (21). The top of the top connector (21) has a through hole. An annular block (22) is fixedly connected to the inner wall of the top connector (21). A one-way valve (23) is fixedly connected to the inner wall of the annular block (22). A ball bearing (24) is provided at the bottom of the top connector (21).

3. The device for collecting autologous hair follicle cell culture samples according to claim 2, characterized in that: The cylindrical block (61) is rotatably connected to the inner wall of the housing (1). A connecting rod (62) is fixedly connected to the outer wall of the cylindrical block (61). One end of a spring (63) is fixedly connected to the inner wall of the housing (1). The other end of the spring (63) is fixedly connected to a positioning block (64). The bottom of the positioning block (64) is a semi-circular groove. There are six positioning blocks (64), and the six positioning blocks (64) are arranged in a circular array.

4. The device for collecting autologous hair follicle cell culture samples according to claim 1, characterized in that: A probe (3) is fixedly connected to the inner wall of the housing (1), and a cutting part (4) is fixedly connected to the bottom of the probe (3).

5. The device for collecting autologous hair follicle cell culture samples according to claim 4, characterized in that: The probe (3) is equipped with a micro air pump (5), which is used to provide suction.

6. The device for collecting autologous hair follicle cell culture samples according to claim 1, characterized in that: The head of the positioning pin (72) is hemispherical, and the outer wall of the collection frame (73) is provided with a hemispherical groove.

7. The device for collecting autologous hair follicle cell culture samples according to claim 1, characterized in that: The outer wall of the lightweight connecting block (715) is piston-connected to the inner wall of the collection frame (73), and the lightweight connecting block (715) is L-shaped.

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