Tail gas exhaust device for bioreactor
By installing a condensation container and pressure detection device in the exhaust gas device of the bioreactor, the problem of filter clogging caused by water vapor condensation was solved, the exhaust efficiency and reliability of the device were improved, and the stability of the biological reaction was ensured.
Patent Information
- Application Number
- CN202423282784.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-30
- Publication Date
- 2026-01-30
- Estimated Expiration
- 2034-12-30
AI Technical Summary
In the exhaust process of existing bioreactors, water vapor condensation causes filter blockage, affecting exhaust efficiency and potentially leading to excessive internal pressure. Furthermore, it is impossible to monitor and replace the filter in a timely manner.
A condensation container is installed between the bioreactor and the filter to condense and collect water vapor in the exhaust gas, and a pressure detection device is installed before the filter to monitor and respond quickly to pressure changes in the filter.
This improved the exhaust efficiency of the bioreactor, avoided problems such as filter clogging and excessive internal pressure, and ensured the stability and reliability of the biological reaction.
Smart Images

Figure CN223846264U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to tail gas purification technical field especially, it is a kind of tail gas exhaust device for bioreactor. BACKGROUND
[0002] Bioreactor is the device system that utilizes enzyme or organism (such as microorganism) the biological function that has, carries out biochemical reaction in vitro, it is a kind of biological function simulator, such as fermentation tank, immobilized enzyme or immobilized cell reactor etc.Important application in wine, pharmaceutical production, concentrated jam, juice fermentation, organic pollutant degradation.
[0003] And in use process, carbon dioxide, hydrogen sulfide etc. Waste gas produced in the respiratory metabolism process of microorganism needs to be discharged through tail gas pipeline, but as sterile environment is needed in the culture process, therefore, filter needs to be connected in tail gas pipeline, to avoid the sterile environment in bioreactor to be destroyed.The existing tail gas discharge process due to there is usually a large amount of water vapor in tail gas, along with the extension of culture time, water vapor in tail gas can condense in filter, to block filter, cause gas in reactor to be unable to discharge, cause the pressure in bioreactor to be too high, dissolved oxygen and ventilation volume change, lead to culture failure.And existing filter cannot monitor filter blockage condition in time, and even if filter blockage is found, it is also difficult to change tail gas collection bottle and air filter under the condition of not changing original exhaust mode.
[0004] Therefore, a tail gas exhaust device for bioreactor is needed to solve the above technical problems. UTILITY MODEL CONTENTS
[0005] The utility model aims at providing a kind of tail gas exhaust device for bioreactor, can liquefy most of water vapor and collect, improve the exhaust efficiency of bioreactor, monitor pressure simultaneously, to change quickly after pressure change, improve the reliability of this tail gas exhaust device.
[0006] To achieve this purpose, the utility model adopts the following technical solutions:
[0007] The tail gas exhaust device for bioreactor includes:
[0008] Condensing vessel, the condensing vessel is communicated with the tail gas outlet of bioreactor, and the condensing vessel is used to condense and collect at least part of water vapor in the tail gas flowing through;
[0009] Filter, one end of the filter is communicated with the outlet of the condensing vessel, and the other end is exhaust port, and the filter is used to filter the tail gas;
[0010] A pressure detection member is arranged between the filter and the condensing container to detect the pressure of the filter.
[0011] Optionally, the condensing container comprises:
[0012] A containing member is arranged between the tail gas outlet of the bioreactor and the filter, and is used to contain the flowing tail gas and collect the condensed water vapor in the tail gas.
[0013] A condensing jacket is arranged around the containing member, and a cooling liquid is circulated in the condensing jacket to cool the tail gas in the containing member to condense part of the water vapor in the tail gas.
[0014] Optionally, two communication joints are arranged on the top of the containing member, and the two communication joints are respectively arranged in communication with the bioreactor and the filter.
[0015] Optionally, the filter is a hydrophobic bag filter.
[0016] Optionally, an air inlet pipe is arranged between the condensing container and the bioreactor, and an air outlet pipe is arranged between the condensing container and the filter, and the pressure detection member is arranged in communication with the air outlet pipe.
[0017] Optionally, a one-way valve is arranged on the air inlet pipe.
[0018] Optionally, the air inlet pipe is a thermoplastic pipe.
[0019] Optionally, the air outlet pipe is a silica gel hose.
[0020] Optionally, the pressure detection member, the filter and the condensing container are sealed and connected by a three-way chuck joint.
[0021] Optionally, the filter and the pressure detection member are one-to-one corresponding to at least two.
[0022] The beneficial effects of the present application are as follows:
[0023] The utility model provides a tail gas exhaust device for bioreactor, through setting up condensing container between bioreactor and filter, make the tail gas first pass through condensing container in the process of discharging, condense part water vapor into liquid water and collect and store in the condensing container, finally pass through filter again and discharge, improved the filter block condition, improved the exhaust efficiency of bioreactor. BRIEF DESCRIPTION OF DRAWINGS
[0024] Figure 1 It is the structure schematic drawing of tail gas exhaust device for bioreactor provided by the utility model specific embodiment,
[0025] Figure 2 It is the structure explosion drawing of bottle cap provided by the utility model specific embodiment,
[0026] Figure 3 It is the structure schematic drawing of condensing jacket provided by the utility model specific embodiment,
[0027] Figure 4 It is the structure explosion drawing of tee chuck joint provided by the utility model specific embodiment.
[0028] In the drawing,
[0029] 10, condensing container, 11, containing piece, 111, bottle body, 112, bottle cap, 1121, cover body, 1122, metal sheet, 1123, communication joint, 1124, first sealing piece, 12, condensing jacket, 121, liquid inlet, 122, liquid outlet, 123, handle,
[0030] 20, filter, 21, air inlet, 22, exhaust port,
[0031] 30, pressure detection piece, 40, air inlet pipe, 50, air outlet pipe, 60, check valve,
[0032] 70, tee chuck joint, 80, second sealing piece, 90, clamp,
[0033] 200, bioreactor. SPECIFIC EMBODIMENT
[0034] The utility model will be described in further detail below with reference to the drawings and embodiments. It can be understood that the specific embodiments described herein are merely intended to explain the utility model, and not to limit the utility model. In addition, it should be noted that, for the sake of description, only the parts related to the utility model are shown in the drawings, not all the structures.
[0035] In the description of the utility model, unless otherwise explicitly specified and limited, the terms "connected", "connected", "fixed" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or it can be integrated; it can be directly connected, or it can be indirectly connected through an intermediate medium, it can be the internal communication of two elements or the interaction relationship of two elements. For ordinary skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific circumstances.
[0036] In the utility model, unless otherwise explicitly specified and limited, the first feature is "on" or "below" the second feature, which can include direct contact between the first and second features, or indirect contact between the first and second features through another feature between them. Moreover, the first feature "on", "above" and "above" the second feature includes that the first feature is directly above and obliquely above the second feature, or only indicates that the horizontal height of the first feature is higher than that of the second feature. The first feature "below", "below" and "below" the second feature includes that the first feature is directly below and obliquely below the second feature, or only indicates that the horizontal height of the first feature is less than that of the second feature.
[0037] In the description of the embodiment, the terms "up", "down", "left", "right", etc. orientation or position relationship is based on the orientation or position relationship shown in the drawings, only for the convenience of description and simplification of operation, and does not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, therefore cannot be understood as a limitation on the utility model. In addition, the terms "first", "second" are only used to distinguish in the description, and have no special meaning.
[0038] The following refers to Figures 1 to 4 The utility model provides a tail gas exhaust device for bioreactor is introduced.
[0039] Please refer to Figure 1Specifically, the exhaust gas device for the bioreactor includes a condenser 10, a filter 20, and a pressure sensor 30. The condenser 10 is connected to the exhaust gas outlet of the bioreactor 200 and is used to condense and collect at least a portion of the water vapor in the flowing exhaust gas. One end of the filter 20 is connected to the outlet of the condenser 10, and the other end is an exhaust port 22. The filter 20 is used to filter the exhaust gas. The pressure sensor 30 is connected between the filter 20 and the condenser 10 to detect the pressure of the filter 20.
[0040] The exhaust gas device for the bioreactor in this embodiment uses a condenser container 10 installed between the bioreactor 200 and the filter 20. This allows the exhaust gas to pass through the condenser container 10 first during discharge, condensing some water vapor into liquid water and collecting and storing it within the condenser container 10. Finally, the gas is filtered and discharged through the filter 20, improving the clogging situation of the filter 20 and increasing the exhaust efficiency of the bioreactor 200. Furthermore, a pressure detection device 30 is installed before the filter 20 to detect the pressure inside the filter 20, preventing excessive internal pressure caused by filter 20 failure or clogging that could lead to bioreactor failure. This facilitates monitoring and rapid maintenance of the exhaust gas device by operators, improving its reliability.
[0041] It is understandable that the filter 20 and the pressure detection element 30 are set in a one-to-one correspondence and the quantity can be changed according to actual needs, without specific limitations here.
[0042] In an optional embodiment, both filter 20 and pressure detection element 30 are provided, which enables the exhaust gas device to quickly discharge and monitor exhaust gas.
[0043] In another optional embodiment, at least two filters 20 and pressure detection elements 30 are provided in a one-to-one correspondence to accelerate the exhaust gas emission rate and ensure that the other filters 20 can still maintain exhaust gas emission when a single filter 20 fails, thereby improving the reliability of the exhaust gas discharge device.
[0044] Please refer to Figures 1 to 3In the embodiment, the condensing container 10 includes a containing member 11 and a condensing jacket 12. One end of the containing member 11 is connected to the tail gas outlet of the bioreactor 200, and the other end is connected to the filter 20. The containing member 11 is used to contain the flowing tail gas and collect the condensed water vapor in the tail gas. The condensing jacket 12 is arranged on the outer periphery of the containing member 11. The cooling liquid circulates in the condensing jacket 12. The condensing jacket 12 is used to cool the tail gas in the containing member 11, so that part of the water vapor in the tail gas is condensed. In use, after the tail gas enters the containing member 11, part of the water vapor in the tail gas is liquefied into liquid water and stored in the containing member 11 due to the cold source provided by the condensing jacket 12 on the outer periphery of the containing member 11.
[0045] Specifically, the containing member 11 includes a bottle body 111 and a bottle cap 112. The bottle cap 112 is sealingly connected to the opening of the bottle body 111. The bottle body 111 is arranged in the condensing jacket 12, so that the containing member 11 can collect and store the water vapor therein, and facilitate subsequent post-processing.
[0046] Optionally, the bottle body 111 is made of glass material that can withstand high temperature and high pressure, so that the containing member 11 will not burst under high temperature and high pressure, and the glass material has good thermal conductivity, which is more convenient for heat exchange between the tail gas in the containing member 11 and the cooling liquid in the condensing jacket 12.
[0047] Further, the top of the containing member 11 is provided with two communication joints 1123, which are respectively connected to the bioreactor 200 and the filter 20. Specifically, the two communication structures are arranged on the bottle cap 112, and one end is in communication with the bottle body 111, so that the containing member 11 can be connected to the bioreactor 200 and the filter 20.
[0048] More specifically, the bottle cap 112 includes a cap body 1121, a metal sheet 1122, and a first sealing member 1124. The metal sheet 1122 is arranged in the cap body 1121. The first sealing member 1124 is arranged on the side of the metal sheet 1122 away from the cap body 1121. The two communication joints 1123 are integrally formed with the metal sheet 1122 and are arranged in the cap body 1121. The first sealing member 1124 is used for sealing between the bottle cap 112 and the bottle body 111. The metal sheet 1122 facilitates the formation of the communication joints 1123, so that the communication joints 1123 can be connected to the external pipeline.
[0049] Optionally, the metal sheet 1122 is made of stainless steel material, which is not easy to rust and deform, and is convenient for sterilization.
[0050] Optionally, the first sealing member 1124 is a sealing ring, a sealing strip or the like, which is not limited here.
[0051] Specifically, the condensing jacket 12 is provided with a liquid inlet 121 and a liquid outlet 122, the liquid inlet 121 is communicated with the outlet of the external cooling liquid device, and the liquid outlet 122 is communicated with the return port of the external cooling liquid device, so as to realize the circulation of the cooling liquid in the condensing jacket 12. More specifically, the liquid inlet 121 is arranged at the position close to the top of the condensing jacket 12, and the liquid outlet 122 is arranged at the position close to the bottom of the condensing jacket 12, so as to realize the rapid cooling of part of the water vapor in the tail gas entering the containing member 11.
[0052] Optionally, the condensing jacket 12 is a barrel-shaped structure, which is provided with a central hole to form an internal mounting space for mounting the containing member 11, and the outer periphery of the containing member 11 is covered by the condensing jacket 12, thereby increasing the heat exchange area.
[0053] Further, the top of the condensing jacket 12 is also provided with a handle 123, so as to facilitate the workers to take and place the condensing jacket 12, and facilitate the operation.
[0054] Optionally, the handle 123 is provided with two handles at intervals, which is more convenient for workers to take and place.
[0055] Further, the condensing container 10 and the bioreactor 200 are communicated through a gas inlet pipe 40, the condensing container 10 and the filter 20 are communicated through a gas outlet pipe 50, and the pressure detection member 30 is communicated and arranged in the gas outlet pipe 50, so as to realize the communication between the condensing container 10 and the bioreactor 200, and realize the communication between the condensing container 10 and the filter 20.
[0056] Optionally, the gas inlet pipe 40 is a thermoplastic pipe, which has a certain thermoplasticity, so that when the filter 20 is blocked and needs to be replaced, the sterile replacement of the tail gas exhaust device can be directly performed without changing the exhaust mode, or the tail gas exhaust device can be added at other tail gas outlets of the bioreactor 200.
[0057] Optionally, the gas outlet pipe 50 is a silica gel hose, which is convenient for sterilization treatment. Further optionally, the gas outlet pipe 50 is a silica gel hose made of high-temperature and high-pressure resistant material, which is convenient for sterilization treatment and can withstand a large pressure without bursting due to excessive pressure.
[0058] Further, the gas inlet pipe 40 is provided with a one-way valve 60, which avoids the problem of backflow of the tail gas when the pressure in the tail gas exhaust device is greater than the pressure of the bioreactor 200, and improves the reliability of the tail gas exhaust device and the bioreactor 200.
[0059] Please refer to Figure 1 In the embodiment, the filter 20 is provided with a gas inlet 21 and a gas outlet 22 at both ends, and the gas inlet 21 and the gas outlet 22 are connected with threaded joints to realize the connection with the external pipeline.
[0060] Optionally, the filter 20 is a hydrophobic capsule filter 20, which has a larger filtering area, can filter more exhaust gas at a time, and improves the exhaust gas discharge efficiency.
[0061] Further optionally, the pore size of the hydrophobic capsule filter 20 is selected to be 0.2-0.45 μm, so as to improve the exhaust gas filtering area and rate.
[0062] Further, the pressure detection piece 30 is selected to be a pressure gauge, which can display the pressure value outside, and is convenient for the operator to monitor.
[0063] Optionally, the pressure detection piece 30 is made of stainless steel, so that it can be sterilized at the same time as the filter 20 after being connected.
[0064] Please refer to Figure 4 Further, the pressure detection piece 30, the filter 20 and the condensing container 10 are sealed and connected through a three-way chuck joint 70, so as to realize the installation of the pressure detection piece 30.
[0065] Specifically, the two ports of the three-way chuck joint 70 are threaded pipes, which are convenient for being communicated with the filter 20 and the condensing container 10 through the gas outlet pipe 50; the third port of the three-way chuck is sealed and connected with the pressure detection piece 30 through a clamp 90, so as to realize the communication and arrangement of the pressure detection piece 30 between the filter 20 and the condensing container 10.
[0066] Optionally, a second sealing piece 80 is arranged between the clamp 90 and the pressure detection piece 30, so as to seal and connect them.
[0067] Optionally, the clamp 90 is made of stainless steel, so as to be sterilized.
[0068] Obviously, the above embodiments of the present application are only examples for clearly illustrating the present application, and are not intended to limit the implementation modes of the present application. For those skilled in the art, various obvious changes, re-adjustments and replacements can be made without departing from the protection scope of the present application. Here, it is unnecessary and impossible to enumerate all the implementation modes. Any modification, equivalent replacement and improvement made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims
1. A tail gas exhaust device for a bioreactor, characterized by, The application relates to a tail gas condensing device for a bioreactor. The device comprises: a condensing container (10) connected to the tail gas outlet of a bioreactor (200), which is used to condense and collect at least part of the water vapor in the flowing tail gas; a filter (20) connected to one end of the condensing container (10) and having an exhaust port (22) at the other end, which is used to filter the tail gas; 2. The off-gas exhaust apparatus for a bioreactor according to claim 1, characterized by, a pressure detection member (30) connected between the filter (20) and the condensing container (10) to detect the pressure of the filter (20). The condensing container (10) comprises: a containing member (11) connected to the tail gas outlet of the bioreactor (200) at one end and connected to the filter (20) at the other end, which is used to contain the flowing tail gas and collect the condensed water vapor in the tail gas; 3. The off-gas exhaust apparatus for a bioreactor according to claim 2, characterized by, a condensing jacket (12) sleeved on the outer periphery of the containing member (11), which circulates cooling liquid and is used to cool the tail gas in the containing member (11) to condense part of the water vapor in the tail gas.
4. The off-gas exhaust apparatus for a bioreactor according to claim 1, characterized by, The top of the containing member (11) is provided with two communication joints (1123) connected to the bioreactor (200) and the filter (20) respectively.
5. The off-gas exhaust apparatus for a bioreactor according to claim 1, wherein The filter (20) is a hydrophobic bag filter (20).
6. The off-gas exhaust apparatus for a bioreactor according to claim 5, characterized by, An air inlet pipe (40) is connected between the condensing container (10) and the bioreactor (200), an air outlet pipe (50) is connected between the condensing container (10) and the filter (20), and the pressure detection member (30) is connected to the air outlet pipe (50).
7. The off-gas exhaust apparatus for a bioreactor according to claim 5, characterized by, A one-way valve (60) is arranged on the air inlet pipe (40).
8. The off-gas exhaust apparatus for a bioreactor according to claim 5, characterized by, The air inlet pipe (40) is a thermoplastic pipe.
9. The off gas exhaust apparatus for a bioreactor according to claim 1, wherein The air outlet pipe (50) is a silica gel hose.
10. The off-gas exhaust apparatus for a bioreactor according to any one of claims 1 to 9, characterized by, The pressure detection member (30), the filter (20) and the condensing container (10) are sealed and connected through a three-way chuck joint (70). The filter (20) and the pressure detection member (30) are provided with at least two one-to-one corresponding ones.