Piroxicam methylate crude product refining device

Abstract

The utility model relates to the technical field of piroxicam methylate, in particular to a piroxicam methylate crude product refining device which comprises a base, a crystallizing tank fixedly mounted at the top of the base through a plurality of supporting legs, a refrigerating mechanism mounted on the outer side surface of the crystallizing tank, a top cover mounted at the top of the crystallizing tank, and a second rotating shaft rotationally connected to the top of the top cover, the second rotating shaft extends into the crystallizing tank, a spiral blade is installed on the side face of the second rotating shaft, and a first driving motor is installed at the top of the top cover. The first driving motor can drive the spiral blade to rotate, a solution at the bottom of the crystallizing tank is conveyed to the top of the crystallizing tank, meanwhile, the first rotating shaft can rotate along with the second rotating shaft under the action of the first gear and the second gear, and then the stirring blade stirs the solution in the crystallizing tank; therefore, the solution is uniformly cooled, and the crystallization effect is improved.

Description

Technical Field

[0001] This utility model relates to the field of piroxicam methyl compounds, and in particular to a device for refining crude piroxicam methyl compounds. Background Technology

[0002] Piroxicam tablets belong to the class of nonsteroidal anti-inflammatory drugs. Piroxicam mainly has analgesic, anti-inflammatory, and antipyretic effects. During the production of piroxicam, it needs to be purified by a refining device.

[0003] Existing refining equipment typically involves feeding a piroxicam mixture into a crystallization tank for cooling, causing the piroxicam to crystallize out, followed by filtration to complete the refining process. However, during crystallization, stirring only by a single agitator shaft within the crystallization tank leads to uneven cooling of the mixture, affecting crystal precipitation. Furthermore, during filtration, the solution containing crystals is usually poured directly into a filter screen, which can clog the screen, resulting in poor performance. Therefore, we propose a refining device for crude piroxicam methyl compounds. Utility Model Content

[0004] The purpose of this invention is to address the aforementioned shortcomings in the existing technology by proposing a device for refining crude piroxicam methyl compounds.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: a device for refining crude piroxicam methyl compounds is designed, including a base, a crystallization tank is fixedly installed on the top of the base by several legs, and a refrigeration mechanism is installed on the outer side of the crystallization tank.

[0006] The top of the crystallization tank is equipped with a top cover, and the top of the top cover is rotatably connected to a second rotating shaft. The second rotating shaft extends into the interior of the crystallization tank, and spiral blades are installed on the side of the second rotating shaft. The top of the top cover is equipped with a first drive motor, and the output shaft of the first drive motor is connected to the top of the second rotating shaft.

[0007] A crossbar is installed on the top side of the second rotating shaft. The bottom ends of the crossbar are rotatably connected to the first rotating shaft. Several stirring blades are installed on the side of the first rotating shaft. The top of each first rotating shaft extends above the crossbar, and a second gear is installed on the top of each first rotating shaft. A connecting sleeve is coaxially provided on the top of the second rotating shaft. The top of the connecting sleeve is fixed to the bottom of the top cover, and a first gear is installed on the bottom of the connecting sleeve. The first gear meshes with two second gears.

[0008] The bottom of the crystallization tank is connected to a discharge pipe, and an electric control valve is installed on the discharge pipe. Below the discharge pipe is an outer shell, and the two sides of the outer shell are fixed to the base by brackets. The top of the outer shell has an opening, and several support shafts are equidistantly arranged inside the outer shell. The two ends of each support shaft are rotatably connected to the outer shell. A conveyor belt is installed inside the outer shell, and the chains on both sides of the conveyor belt are connected to the sprockets at both ends of the support shaft. A second drive motor is connected to the end of the support shaft at one end of the outer shell, and the second drive motor is fixed to the side of the outer shell.

[0009] An air collection box is located between the two support shafts near the second drive motor. Both ends of the air collection box are fixed to the outer shell. An air inlet pipe is installed at one end of the air collection box, and the other end of the air inlet pipe passes through the outer shell and is connected to the air pump. The air pump is fixed to the base. Several air outlets are opened at the bottom of the air collection box. An inclined guide plate is installed at one end of the outer shell, with one end of the guide plate located below the air outlet. A collection bucket is also installed on the top of the base, located below the guide plate.

[0010] Preferably, the dimensions of the helical blades decrease sequentially from top to bottom.

[0011] Preferably, the bottom of the second rotating shaft is provided with a connecting ring, the inside of which is fixed to the side of the second rotating shaft by several support rods, and several scrapers are installed on the side of the connecting ring, with the side of the scrapers fitting with the bottom side wall of the crystallizing tank.

[0012] Preferably, the refrigeration mechanism includes a cold liquid pipe fixed to the side of the outer casing, two symmetrically installed rims on the side of the outer casing, an insulation cover installed between the two rims, an annular space formed between the insulation cover and the side wall of the outer casing, the cold liquid pipe located in the annular space, a refrigeration unit installed at one end of the base, the two ends of the cold liquid pipe connected to the refrigeration unit through pipes, and a temperature sensor installed on one side of the top of the top cover.

[0013] Preferably, several strip baffles are installed at equal intervals on the outer side of the conveyor belt, and one side of the strip baffle is fitted with the inner wall of the outer shell with a clearance.

[0014] Preferably, baffles are vertically installed on both sides of the top of the guide plate.

[0015] Preferably, an inlet pipe is installed on one side of the top of the top cover.

[0016] Preferably, a drain pipe is installed at the bottom of the outer casing away from the guide plate, and a filter screen is installed at the top of the drain pipe.

[0017] Preferably, a control cabinet is installed on one side of the support leg. The controller in the control cabinet is connected to the first drive motor, the second drive motor, the electric control valve and the air pump through wires. The controller is also connected to the refrigeration unit and the temperature sensor through wires.

[0018] The design scheme proposed in this utility model has the following beneficial effects in application:

[0019] 1. The first drive motor can drive the spiral blades to rotate, transporting the solution at the bottom of the crystallization tank to the top of the crystallization tank. At the same time, under the action of the first gear and the second gear, the first rotating shaft can rotate along with the second rotating shaft, thereby making the stirring blades stir the solution in the crystallization tank. The stirring is thorough, the solution is cooled evenly, and the crystallization effect is improved.

[0020] 2. The crystallized solution can be filtered by the conveyor belt. The piroxicam methyl compound crystals can be filtered by the conveyor belt 18 and transported to the collection tank for collection. Then, the air pump blows the outside air through the air outlet to the bottom of the conveyor belt to prevent the piroxicam methyl compound crystals from adhering to the conveyor belt and improve the use effect. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of the structure of this utility model;

[0022] Figure 2 This is a side view of the structure of this utility model;

[0023] Figure 3 This is a side sectional view of the crystallization tank structure of this utility model;

[0024] Figure 4 This is a side sectional view of the outer shell structure of this utility model.

[0025] In the diagram: 1. Base; 2. Outer shell; 3. Support leg; 4. Insulation cover; 5. Edge; 6. Crystallization tank; 7. First gear; 8. Scraper; 9. Stirring blade; 10. First rotating shaft; 11. Liquid inlet pipe; 12. First drive motor; 13. Top cover; 14. Spiral blade; 15. Connecting ring; 16. Cold liquid pipe; 17. Strip baffle; 18. Conveyor belt; 19. Guide plate; 20. Baffle plate; 21. Collection bucket; 22. Air pump; 23. Air inlet pipe; 24. Second drive motor; 25. Support shaft; 26. Discharge pipe; 27. Electrically controlled valve; 28. Control cabinet; 29. ​​Air outlet; 30. Liquid drain pipe; 31. Crossbar; 32. Second gear; 33. Connecting sleeve; 34. Temperature sensor; 35. Gas collection box; 36. Second rotating shaft; 37. Refrigeration unit. Detailed Implementation

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0027] Reference Figures 1-4A device for refining crude piroxicam methyl compounds includes a base 1, a crystallization tank 6 fixedly mounted on the top of the base 1 by several legs 3, a top cover 13 mounted on the top of the crystallization tank 6, a control cabinet 28 mounted on one side of the legs 3, and a controller installed inside the control cabinet 28, the controller being either a control motherboard or a host computer.

[0028] like Figure 1 and Figure 2 As shown, a heating mechanism is installed on the outer side of the crystallization tank 6. The heating mechanism includes a cold liquid pipe 16 fixed to the side of the outer shell 2, two symmetrically installed side panels 5 on the side of the outer shell 2, and a heat insulation cover 4 installed between the two side panels 5. Under the action of the heat insulation cover 4, the heat in the crystallization tank 6 can be isolated, reducing heat loss.

[0029] like Figure 1 and Figure 3 As shown, an annular space is formed between the insulation cover 4 and the side wall of the outer shell 2. The cold liquid pipe 16 is located in this annular space. A refrigeration unit 37 is installed at one end of the base 1. The two ends of the cold liquid pipe 16 are connected to the refrigeration unit 37 through pipes. A temperature sensor 34 is installed on one side of the top of the top cover 13. The temperature sensor 34 and the refrigeration unit 37 are both connected to the controller through wires. The temperature in the crystallization tank 6 is detected by the temperature sensor 34, and the detection data is transmitted to the controller. The controller controls the refrigeration unit 37 to work, and transports the low-temperature liquid through the pipe to the cold liquid pipe 16 to cool the inside of the crystallization tank 6, so that the temperature inside the crystallization tank 6 is maintained within the preset temperature range.

[0030] like Figure 1 As shown, a second rotating shaft 36 is rotatably connected to the top of the top cover 13. The second rotating shaft 36 extends into the crystallization tank 6. A spiral blade 14 is installed on the side of the second rotating shaft 36. A first drive motor 12 is installed on the top of the top cover 13. The output shaft of the first drive motor 12 is connected to the top of the second rotating shaft 36. The first drive motor 12 is connected to the controller through a wire. The first drive motor 12 can drive the second rotating shaft 36 to rotate, thereby causing the spiral blade 14 to rotate. Under the action of the spiral blade 14, the solution at the bottom of the crystallization tank 6 can be transported to the top of the crystallization tank 6, so that the solution is cooled evenly.

[0031] like Figure 1 As shown, an inlet pipe 11 is installed on one side of the top of the top cover 13. The crude piroxicam methyl compound solution after processing can be transported to the crystallization tank 6 through the inlet pipe 11 for crystallization and purification.

[0032] It should be noted that the size of the spiral blades 14 decreases from top to bottom, so that the bottom of the spiral blades 14 will not collide with the inner wall of the crystallization tank 6, thus preventing damage to the spiral blades 14.

[0033] like Figure 3As shown, a crossbar 31 is installed on the top side of the second rotating shaft 36. The bottom ends of the crossbar 31 are rotatably connected to the first rotating shaft 10. Several stirring blades 9 are installed on the sides of the first rotating shaft 10. The top of each first rotating shaft 10 extends above the crossbar 31, and a second gear 32 is installed on the top of each first rotating shaft 10. A connecting sleeve 33 is coaxially provided on the top of the second rotating shaft 36. The top of the connecting sleeve 33 is fixed to the bottom of the top cover 13, and a first gear 7 is installed on the bottom of the connecting sleeve 33. The first gear 7 meshes with two second gears 32. In actual use, the first drive motor 12 drives the second rotating shaft 36 to rotate, which in turn drives the crossbar 31 to rotate. This causes the two second gears 32 to rotate relative to the first gear 7, which in turn drives the two first rotating shafts 10 to rotate. As a result, the stirring blades 9 on the first rotating shaft 10 rotate synchronously along the first rotating shaft 10 while following the rotation of the second rotating shaft 36, thus fully stirring the solution in the crystallization tank 6.

[0034] It should be noted that the side of the stirring blade 9 closest to the inside of the outer shell 2 is fitted with the inner wall of the outer shell 2 with a gap. In this way, during the stirring process, the stirring blade 9 can scrape off the crystals adhering to the inner wall of the outer shell 2, thus preventing crystals from remaining in the crystallization tank 6.

[0035] It should be noted that, as Figure 3 As shown, a connecting ring 15 is provided at the bottom of the second rotating shaft 36. The inside of the connecting ring 15 is fixed to the side of the second rotating shaft 36 by several support rods. Several scrapers 8 are installed on the side of the connecting ring 15. The side of the scraper 8 is fitted with the bottom side wall of the crystallization tank 6 with a clearance. In actual use, the scraper 8 can scrape off the crystals adhering to the bottom side wall of the crystallization tank 6, so as to avoid crystals remaining in the crystallization tank 6.

[0036] like Figure 1 As shown, a discharge pipe 26 is connected to the bottom of the crystallization tank 6. An electric control valve 27 is installed on the discharge pipe 26. The electric control valve 27 is connected to the controller through a wire. In actual use, the electric control valve 27 can control the opening and closing of the discharge pipe 26. After the piroxicam methyl compound crystallizes, the controller can control the electric control valve 27 to open and discharge the solution of crystals and other impurities from the crystallization tank 6.

[0037] like Figure 1 and Figure 4As shown, a housing 2 is located below the discharge pipe 26. The two sides of the housing 2 are fixed to the base 1 by brackets. The top of the housing 2 has an opening. Several support shafts 25 are equidistantly arranged inside the housing 2. Both ends of each support shaft 25 are rotatably connected to the housing 2. A conveyor belt 18 is provided inside the housing 2. The chains on both sides of the conveyor belt 18 are connected to the sprockets at both ends of the support shafts 25. The piroxicam methyl ester crystals and impurity solutions discharged from the discharge pipe 26 fall onto the conveyor belt 18. The crystals remain on the conveyor belt 18, and the impurity solution flows through the conveyor belt 18 to the bottom of the housing 2, thus separating the piroxicam methyl ester crystals and impurity solutions.

[0038] It should be noted that a drain pipe 30 is installed at the bottom of the outer shell 2 away from the guide plate 19. A filter screen is installed at the top of the inside of the drain pipe 30. The impurity solution that flows through the conveyor belt 18 to the bottom of the outer shell 2 can be filtered by the filter screen and then discharged along the drain pipe 30 to complete the purification of piroxicam methyl crystals.

[0039] like Figure 1 and Figure 4 As shown, a second drive motor 24 is connected to the end of the support shaft 25 located at one end of the outer shell 2. The second drive motor 24 is fixed to the side of the outer shell 2. An inclined guide plate 19 is installed at one end of the outer shell 2. A collection bucket 21 is also installed on the top of the base 1. The collection bucket 21 is located below the guide plate 19. The second drive motor 24 is connected to the controller through a wire. The second drive motor 24 can drive the support shaft 25 to rotate, which in turn drives the conveyor belt 18 to rotate, transporting the crystals falling on the conveyor belt 18 to the guide plate 19, and then transporting them along the guide plate 19 into the collection bucket 21 for collection.

[0040] It should be noted that, as Figure 1 As shown, baffle plates 20 are vertically installed on both sides of the top of the guide plate 19. The baffle plates 20 can block the two sides of the guide plate 19 to prevent the piroxicam methyl ester crystals from falling from the two sides of the guide plate 19 as they move along the guide plate 19.

[0041] like Figure 1 and Figure 4As shown, an air collection box 35 is provided between the two support shafts 25 near the second drive motor 24. Both ends of the air collection box 35 are fixed to the outer shell 2. An air inlet pipe 23 is installed at one end of the air collection box 35, and the other end of the air inlet pipe 23 passes through the outer shell 2 and is connected to the air pump 22. The air pump 22 is fixed to the base 1. Several air outlet holes 29 are opened at the bottom of the air collection box 35. The air pump 22 is connected to the controller through wires. In actual use, the air pump 22 can deliver external air to the air collection box 35 and blow it from the air outlet holes 29 to the bottom of the conveyor belt 18, blowing off the piroxicam methylide crystals adhering to the bottom of the conveyor belt 18. The piroxicam methylide crystals fall onto the guide plate 19 and fall into the collection bucket 21 along the guide plate 19 for collection, preventing the piroxicam methylide crystals from remaining on the conveyor belt 18.

[0042] Specifically, in use, the operator delivers the piroxicam methyl compound solution to the crystallization tank 6 through the inlet pipe 11. Simultaneously, the controller controls the refrigeration unit 37 to operate, which delivers coolant through a pipe to the cold liquid pipe 16, thereby cooling the interior of the crystallization tank 6. The temperature in the crystallization tank 6 is monitored by the temperature sensor 34, ensuring the temperature reaches a preset value. The piroxicam methyl compound in the solution cools, crystallizes, and precipitates. During the crystallization process, the controller controls the first drive motor 12, which drives the second rotating shaft 36 to rotate. This causes the spiral blades 14 to transport the solution from the bottom of the crystallization tank 6 to the top. Simultaneously, with the cooperation of the first gear 7 and the second gear 32, the stirring blades 9 on the first rotating shaft 10 rotate synchronously with both the second and first rotating shafts 36, stirring the solution and ensuring uniform cooling. Pyroxicam methyl ester can crystallize and precipitate completely. After precipitation, the controller opens the electronically controlled valve 27, allowing the crystallized pyroxicam methyl ester and other components to be discharged along the discharge pipe 26 onto the conveyor belt 18. The crystallized pyroxicam methyl ester remains on the conveyor belt 18, while other impurities flow through the conveyor belt 18 to the bottom of the outer casing 2 and are discharged along the drain pipe 30. Simultaneously, the controller controls the second drive motor 24 and the air pump 22 to operate. 4. The conveyor belt 18 is moved to transport the crystallized piroxicam methyl compound to the guide plate 19 and flow along the guide plate 19 to the collection tank 21 for collection. During the separation and crystallization process, the air pump 22 delivers external air to the gas collection box 35 through the air inlet pipe 23. The air is finally sprayed onto the surface of the conveyor belt 18 through the air outlet 29, blowing the crystals adhering to the conveyor belt 18 to the guide plate 19 and finally flowing along the guide plate 19 to the collection tank 21 for collection, thus avoiding residue.

[0043] Furthermore, such as Figure 1As shown, several strip baffles 17 are equidistantly installed on the outer side of the conveyor belt 18. One side of the strip baffle 17 is fitted with the inner wall of the outer shell 2 with a gap. When the mixture of piroxicam methyl ester crystals and other impurity solutions discharged from the discharge pipe 26 flows onto the conveyor belt 18, the strip baffles 17 can block the piroxicam methyl ester crystals, preventing the crystals from flowing to the bottom of the outer shell 2 with other impurity solutions, so as not to affect the refining effect.

[0044] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A device for refining crude piroxicam methyl compounds, comprising a base (1), characterized in that: A crystallization tank (6) is fixedly installed on the top of the base (1) by several legs (3), and a refrigeration mechanism is installed on the outer side of the crystallization tank (6). A top cover (13) is installed on the top of the crystallization tank (6). A second rotating shaft (36) is rotatably connected to the top of the top cover (13). The second rotating shaft (36) extends into the crystallization tank (6). Spiral blades (14) are installed on the side of the second rotating shaft (36). A first drive motor (12) is installed on the top of the top cover (13). The output shaft of the first drive motor (12) is connected to the top of the second rotating shaft (36). A crossbar (31) is installed on the top side of the second rotating shaft (36). The bottom ends of the crossbar (31) are rotatably connected to the first rotating shaft (10). Several stirring blades (9) are installed on the side of the first rotating shaft (10). The top of each first rotating shaft (10) extends above the crossbar (31), and a second gear (32) is installed on the top of each first rotating shaft (10). A connecting sleeve (33) is coaxially provided on the top of the second rotating shaft (36). The top of the connecting sleeve (33) is fixed to the bottom of the top cover (13), and a first gear (7) is installed on the bottom of the connecting sleeve (33). The first gear (7) meshes with two second gears (32). The bottom of the crystallization tank (6) is connected to a discharge pipe (26), and an electric control valve (27) is installed on the discharge pipe (26). A shell (2) is located below the discharge pipe (26). The shell (2) is fixed to the base (1) on both sides by brackets. The top of the shell (2) is open. Several support shafts (25) are equidistantly arranged inside the shell (2). Both ends of each support shaft (25) are rotatably connected to the shell (2). A conveyor belt (18) is provided inside the shell (2). The chains on both sides of the conveyor belt (18) are connected to the sprockets at both ends of the support shaft (25). A second drive motor (24) is connected to the end of the support shaft (25) at one end of the shell (2). The second drive motor (24) is fixed to the side of the shell (2). An air collection box (35) is provided between the two support shafts (25) near the second drive motor (24). Both ends of the air collection box (35) are fixed on the outer shell (2). An air inlet pipe (23) is installed at one end of the air collection box (35). The other end of the air inlet pipe (23) passes through the outer shell (2) and is connected to the air pump (22). The air pump (22) is fixed on the base (1). Several air outlets (29) are opened at the bottom of the air collection box (35). An inclined guide plate (19) is installed at one end of the outer shell (2). One end of the guide plate (19) is located below the air outlet (29). A collection bucket (21) is also installed on the top of the base (1). The collection bucket (21) is located below the guide plate (19).

2. The apparatus for refining crude piroxicam methyl compound according to claim 1, characterized in that: The dimensions of the helical blades (14) decrease sequentially from top to bottom.

3. The apparatus for refining crude piroxicam methyl compound according to claim 2, characterized in that: The bottom of the second rotating shaft (36) is provided with a connecting ring (15). The inside of the connecting ring (15) is fixed to the side of the second rotating shaft (36) by several support rods. Several scrapers (8) are installed on the side of the connecting ring (15). The side of the scraper (8) is in clearance fit with the bottom side wall of the crystallizer (6).

4. The apparatus for refining crude piroxicam methyl compound according to claim 1, characterized in that: The refrigeration mechanism includes a cold liquid pipe (16) fixed to the side of the outer shell (2), two symmetrically installed side panels (5) on the side of the outer shell (2), an insulation cover (4) installed between the two side panels (5), an annular space is formed between the insulation cover (4) and the side wall of the outer shell (2), the cold liquid pipe (16) is located in the annular space, a refrigeration unit (37) is installed at one end of the base (1), the two ends of the cold liquid pipe (16) are connected to the refrigeration unit (37) through pipes, and a temperature sensor (34) is installed on one side of the top of the top cover (13).

5. The apparatus for refining crude piroxicam methyl compound according to claim 1, characterized in that: Several strip baffles (17) are installed at equal intervals on the outer side of the conveyor belt (18), and one side of the strip baffles (17) is fitted with the inner wall of the outer shell (2) with a clearance.

6. The apparatus for refining crude piroxicam methyl compound according to claim 1, characterized in that: Both sides of the top of the guide plate (19) are vertically installed with baffle plates (20).

7. The apparatus for refining crude piroxicam methyl compound according to claim 1, characterized in that: An inlet pipe (11) is installed on one side of the top of the top cover (13).

8. The apparatus for refining crude piroxicam methyl compound according to claim 1, characterized in that: A drain pipe (30) is installed at the bottom of the outer shell (2) away from the guide plate (19), and a filter screen is installed at the top of the inside of the drain pipe (30).

9. The apparatus for refining crude piroxicam methyl compound according to claim 4, characterized in that: A control cabinet (28) is installed on one side of the support leg (3). The controller in the control cabinet (28) is connected to the first drive motor (12), the second drive motor (24), the electric control valve (27) and the gas pump (22) respectively through wires. The controller is also connected to the refrigeration unit (37) and the temperature sensor (34) respectively through wires.

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