Device for ultrasonic sample crushing

Abstract

The utility model discloses a device for breaking ultrasonic samples, which comprises an outer sleeve cup and a sample cup holder arranged inside the outer sleeve cup, a plurality of longitudinally arranged clamping grooves are arranged on the inner wall of the outer sleeve cup, a plurality of longitudinally arranged protruding inserting pieces are fixed on the side face of the sample cup holder, and when the protruding inserting pieces are inserted into the clamping grooves in a sliding mode, the sample cup holder is fixed on the outer sleeve cup. Compared with the prior art, the ultrasonic crushing device has the advantages that in the prior art, samples are prone to toppling over in the ultrasonic crushing process, the cooling effect is poor, and an ultrasonic amplitude-change pole possibly has no-load damage to an instrument due to the fact that the positions of the samples sink. Through the arrangement of the clamping grooves and the protruding insertion pieces of the outer sleeve cup and the sample cup holder, stable fixation and full cooling of a sample are achieved, the sample is prevented from sinking, and therefore the efficiency and safety of ultrasonic sample breaking are improved.

Description

Technical Field

[0001] This utility model belongs to the field of laboratory equipment technology, specifically relating to a device for ultrasonic sample crushing. Background Technology

[0002] An ultrasonic cell disruptor (also called an ultrasonic cell homogenizer or ultrasonic emulsifier) ​​is a multifunctional and versatile instrument that utilizes the cavitation effect of ultrasound in liquids. It can be used to disrupt various cells, bacteria, viruses, and plant and animal tissues, and can also be used for emulsification, separation, homogenization, extraction, defoaming, cleaning, preparation and dispersion of nanomaterials, and acceleration of chemical reactions. It features over-temperature, overload, and time alarm functions, can store 20 sets of data, and can process samples from 100μl to 600ml.

[0003] Chinese utility model patent CN209568115U discloses an ultrasonic cell disruptor. In use, a test tube is secured with a test tube clamp, the door is closed, and the ultrasonic generator and transducer are moved downwards and inserted into the sample in the beaker or test tube to disrupt the sample. Existing ultrasonic cell disruptors (such as the Scientz-I ID ultrasonic cell disruptor from Ningbo Xinzhi Biotechnology Co., Ltd.) have the following structural schematic diagram: Figure 1 As shown, the ultrasonic disruptor includes a main body 100, a sample placement tray 102 at the bottom of the main body 100, and an ultrasonic probe 101 at the top of the main body 100. The ultrasonic probe 101 is also called an ultrasonic transducer, and its principle is as described in CN209568115U.

[0004] Precautions for using existing ultrasonic disruptors: Never run them empty (the ultrasonic amplitude transformer must be inserted into the sample before turning on the machine); the amplitude transformer (ultrasonic probe) should be submerged in water to a depth of about 15mm, and the liquid level should ideally be at least 30mm. The probe should be centered and not touching the wall. Ultrasonic waves are vertical longitudinal waves; if inserted too deeply, convection will not be easily formed, affecting the disruption efficiency.

[0005] The current pain points in ultrasonic fragmentation of laboratory samples, based on existing technology, are as follows: instrument manufacturers do not provide compatible ultrasonic fragmentation kits, requiring users to add ice to a large beaker and then insert a small beaker or test tube containing the sample into the ice. This approach presents three main risks: 1) The small beaker containing the sample cannot be reliably and stably inserted into the ice, lacking fixation and prone to tipping over; 2) Because the ice is a granular or blocky solid, it cannot fit tightly against the wall of the small beaker, resulting in poor cooling; 3) During ultrasonication, the ice gradually melts, causing the small beaker to sink, resulting in a shallower insertion depth of the ultrasonic amplitude rod into the sample, or even causing it to detach from the liquid surface, leading to instrument malfunction and potential damage. Utility Model Content

[0006] The purpose of this invention is to address the shortcomings of existing technologies by providing a device for ultrasonic sample breaking to solve the problems in the background art.

[0007] This utility model provides the following technical solution: a device for ultrasonic sample crushing, characterized in that: it includes an outer cup and a sample cup holder disposed inside the outer cup, the inner wall of the outer cup is provided with a plurality of longitudinally arranged slots, and the side of the sample cup holder is fixed with a plurality of longitudinally arranged protruding inserts, and when the protruding inserts are slidably inserted into the slots, the bottom of the sample cup holder does not contact the bottom of the outer cup.

[0008] Compared with the prior art, the beneficial effects of this utility model are: the prior art has problems such as the sample being easy to tip over during ultrasonic crushing, poor cooling effect, and the ultrasonic amplitude rod being damaged by no load due to the sample sinking. This utility model achieves stable fixation of the sample, sufficient cooling, and prevention of sample sinking by setting the slot and protruding insert of the outer cup and sample cup holder, thereby improving the efficiency and safety of ultrasonic sample crushing. Attached Figure Description

[0009] Figure 1 This is a schematic diagram of an existing ultrasonic crusher.

[0010] Figure 2 This is a schematic diagram of the exploded structure of this utility model.

[0011] Figure 3 This is a frontal cross-sectional view of the present invention.

[0012] Figure 4 This is a three-dimensional structural diagram of the present invention. Detailed Implementation

[0013] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0014] Please see Figure 1-4This utility model discloses a device for ultrasonic sample breaking, comprising an outer cup 10 and a sample cup holder 20 disposed inside the outer cup 10. The inner wall of the outer cup 10 is provided with several longitudinally arranged slots 11, and the side of the sample cup holder 20 is fixed with several longitudinally arranged protruding inserts 21. In use, an ice-water mixture or ice water is added to the outer cup 10, the sample to be ultrasonically broken (such as cell fluid or bacterial fluid) is added to the sample cup holder 20, and then the plate-shaped protruding inserts 21 on the sample cup holder 20 are aligned with the corresponding slots 11 on the outer cup 10 and inserted, thereby fixing the sample cup holder 20 and the outer cup 10.

[0015] The protruding insert 21 and the slot 11 allow the sample cup holder 20 containing the sample to be stably inserted into the ice-water mixture, preventing it from tipping over. In addition, due to the supporting effect of the protruding insert 21 and the slot 11, the ice-water mixture can be used instead of ice cubes, which can enhance the effect of the ice bath.

[0016] In order to ensure that the sample is sufficiently cooled, when the protruding insert 21 slides into the slot 11, the bottom of the sample cup holder 20 does not contact the bottom of the outer cup 10. In this way, the bottom of the sample cup holder 20 can also make good contact with the ice-water mixture.

[0017] In some embodiments, there are three slots 11, and the slots 11 are equidistantly arranged around the inner wall of the outer cup 10. The number of protruding inserts 21 is equal to that of the slots 11 and their positions correspond to each other.

[0018] In some embodiments, when the protruding insert 21 is inserted into the slot 11, the bottom of the sample cup holder 20 is 5cm away from the bottom of the outer cup, and the upper edge of the opening of the sample cup holder 20 is flush with the upper edge of the opening of the outer cup 10.

[0019] In order to allow the ice-water mixture to act for a longer time, the upper part of the outer cup 10 and the sample cup holder 20 is provided with a heat-insulating cover plate 30. The heat-insulating cover plate 30 has a through hole 31 in the middle for fitting onto the sample cup holder 20, and the bottom edge of the heat-insulating cover plate 30 is embedded with a slot 32 for inserting the upper port of the outer cup 10.

[0020] The insulation cover plate 30 is made of rubber.

[0021] The thickness of the protruding insert 21 is between 1.5mm and 5mm.

[0022] In summary, this utility model aims to realize a device for ultrasonic sample breaking. The device, through the design of the slot and protruding insert of the outer cup and the sample cup holder, ensures that the sample is stable and fully cooled in the ice-water mixture, while avoiding the problem of instrument emptying caused by the sample sinking during ultrasonication, thereby improving the efficiency and safety of ultrasonic sample breaking.

[0023] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A device for ultrasonic sample breaking, characterized in that: The device includes an outer cup and a sample cup holder disposed inside the outer cup. The inner wall of the outer cup is provided with several longitudinally arranged slots, and the side of the sample cup holder is fixed with several longitudinally arranged protruding inserts. When the protruding inserts are slidably inserted into the slots, the bottom of the sample cup holder does not contact the bottom of the outer cup.

2. The device for ultrasonic sample breaking according to claim 1, characterized in that: The number of slots is [number], and the slots are equidistantly arranged around the inner wall of the outer cup. The number of protruding inserts is equal to the number of slots and their positions correspond to each other.

3. The device for ultrasonic sample crushing according to claim 1, characterized in that: When the protruding insert is inserted into the slot, the bottom of the sample cup holder is 5cm away from the bottom of the outer cup, and the upper edge of the sample cup holder is flush with the upper edge of the outer cup.

4. The device for ultrasonic sample breaking according to claim 1, characterized in that: The outer cup and the upper part of the sample cup holder are provided with a heat-insulating cover plate. The heat-insulating cover plate has a through hole in the middle for fitting onto the sample cup holder, and the bottom edge of the heat-insulating cover plate is embedded with a slot for inserting the upper end of the outer cup.

5. The device for ultrasonic sample breaking according to claim 4, characterized in that: The heat-insulating cover is made of rubber.

6. The device for ultrasonic sample breaking according to claim 1, characterized in that: The thickness of the protruding insert is between 1.5mm and 5mm.

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