High-stability microfluidic mixer

Abstract

The utility model relates to the technical field of microfluidics, and discloses a high-stability microfluidic mixer which comprises a bottom plate, a transparent glass cover is arranged at the top end of the bottom plate, and a mixing assembly is arranged on the rear side of the left end of the transparent glass cover; the mixing assembly comprises a first sample injection connector, the first sample injection connector is formed in the rear side of the left end of a transparent glass cover, a second sample injection connector is formed in the front side of the left end of the transparent glass cover, a mixing pool is formed in the left side of the middle of the top end of the bottom plate, and the right end of the mixing pool communicates with a mixing flow channel; and the other end of the mixing flow channel is communicated with a winding channel. According to the utility model, fluid can be introduced into the mixing tank through the connecting pipeline by virtue of the first sample introduction interface and the second sample introduction interface, then enters the communicated winding channel through the mixing flow channel, and finally flows out of the sample outlet interface through the capillary channel, so that different fluids can be mixed when flowing in the channel; therefore, the fluid mixing uniformity is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to micro -fluidic technique field especially relates to a kind of high stability micro -fluidic mixer. BACKGROUND

[0002] As an important part of micro -fluidic technology, the development of micro -fluidic mixer has received extensive attention. This device can realize the rapid and uniform mixing of samples in microchannels or microcavities, and is suitable for the sufficient mixing of various reactants under microscale conditions. With the growing demand in the fields of engineering, biotechnology and medicine, micro -fluidic mixer has developed rapidly, and has been widely used in biomedical diagnostic research, DNA analysis, chemical synthesis and genomics analysis. These applications require precise control and rapid mixing of microfluids, which is crucial for the practical development and application of micro -fluidic systems and chip laboratories for various reagent and sample analysis and liposome generation.

[0003] The prior art has the following defects or problems:

[0004] The existing micro -fluidic mixer often has the problems of low mixing efficiency and poor mixing uniformity during mixing, especially when dealing with trace fluid. Due to factors such as fluid viscosity and surface tension, mixing stability becomes a technical problem.

[0005] It should be noted that the above content belongs to the technical cognition of the inventor and does not necessarily constitute prior art. INVENTION CONTENTS

[0006] In order to make up for the above shortcomings, the utility model provides a kind of high stability micro -fluidic mixer, to improve the problem of low mixing efficiency and poor mixing uniformity of micro -fluidic mixer in prior art during mixing.

[0007] In order to achieve the above purpose, the utility model adopts the following technical scheme: a kind of high stability micro -fluidic mixer, including bottom plate, the top of the bottom plate is provided with transparent glass cover, the left end rear side of the transparent glass cover is provided with mixing assembly;

[0008] The mixing assembly includes sample inlet one, the sample inlet one is opened in the left end rear side of transparent glass cover, the left end front side of the transparent glass cover is provided with sample inlet two, the top left side of the bottom plate is provided with mixing pool, the right end of the mixing pool is communicated with mixing flow channel, the other end of the mixing flow channel is communicated with serpentine channel, the other end of the serpentine channel is communicated with capillary tube, the rear end of the bottom plate is provided with sample outlet, the bottom end of the bottom plate is provided with anti -skid component.

[0009] As a further description of the above technical scheme:

[0010] The anti-skid assembly comprises two mounting grooves, both of which are arranged at the bottom end of the bottom plate, and both of the inner top walls of the two mounting grooves are provided with double-sided adhesive layers, and the bottom end of both of the double-sided adhesive layers is fixedly connected with an anti-skid rubber plate.

[0011] As a further description of the above technical solution:

[0012] The first sample inlet is communicated with the left rear end of the mixing pool through a communication pipeline, and the second sample inlet is communicated with the left front end of the mixing pool through a communication pipeline.

[0013] As a further description of the above technical solution:

[0014] The bottom end of the bottom plate is fixedly connected with a micro driver, and the output end of the micro driver is fixedly connected with an eddy current generator.

[0015] As a further description of the above technical solution:

[0016] The end of the capillary pipeline away from the meandering channel is communicated with the sample outlet, and the eddy current generator is arranged in the mixing pool.

[0017] As a further description of the above technical solution:

[0018] The top end of the transparent glass cover is provided with an escape port.

[0019] As a further description of the above technical solution:

[0020] The right side of the bottom plate is fixedly connected with an electromagnetic driver, and the output end of the electromagnetic driver is fixedly connected with an electromagnetic plate.

[0021] As a further description of the above technical solution:

[0022] The top right side of the bottom plate is fixedly connected with a microcontroller, and the front right side of the bottom plate is provided with a sensor external interface.

[0023] The utility model has the advantages of:

[0024] 1、The utility model discloses a fluid mixing device, which comprises a bottom plate, a transparent glass cover, a mixing pool, a first sample inlet, a second sample inlet, a communication pipeline, a capillary pipeline and a sample outlet.

[0025] 2. The utility model discloses, through setting up two installation grooves in the bottom end of bottom plate, and setting up a double -sided adhesive layer in the inner top wall of two installation grooves, and fixing antiskid rubber plate in the installation groove through double -sided adhesive layer, can enhance the friction of bottom plate bottom end, thereby preventing the influence that the mixing of fluid is caused by the sliding of bottom plate. BRIEF DESCRIPTION OF DRAWINGS

[0026] Figure 1 A high-stability microfluidic mixer is provided in the utility model;

[0027] Figure 2 A high-stability microfluidic mixer is provided in the utility model;

[0028] Figure 3 A high-stability microfluidic mixer is provided in the utility model;

[0029] Figure 4 A high-stability microfluidic mixer is provided in the utility model;

[0030] Legend:

[0031] 1, bottom plate, 2, transparent glass cover, 3, sample inlet one, 4, sample inlet two, 5, mixing pool, 6, mixing flow channel, 7, meandering channel, 8, capillary channel, 9, sample outlet, 10, installation groove, 11, double -sided adhesive layer, 12, antiskid rubber plate, 13, micro driver, 14, vortex generator, 15, escape gas port, 16, electromagnetic driver, 17, electromagnetic plate, 18, microcontroller, 19, sensor external interface. DETAILED DESCRIPTION

[0032] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.

[0033] Reference Figure 1 And Figure 2 An embodiment provided by the utility model: a high-stability microfluidic mixer, comprising a bottom plate 1, the top end of the bottom plate 1 is provided with a transparent glass cover 2, the left end rear side of the transparent glass cover 2 is provided with a mixing assembly;

[0034] The mixing assembly comprises a sample inlet 3, which is arranged on the left rear side of the transparent glass cover 2; a sample inlet 4, which is arranged on the left front side of the transparent glass cover 2; a mixing pool 5, which is arranged on the left middle top of the base plate 1; a mixing flow channel 6, which is connected to the right end of the mixing pool 5; a meandering channel 7, which is connected to the other end of the mixing flow channel 6; a capillary channel 8, which is connected to the other end of the meandering channel 7; a sample outlet 9, which is arranged on the rear end of the base plate 1; and an anti-skid assembly, which is arranged on the bottom end of the base plate 1.

[0035] Specifically, the gas discharged through the gas escape port 15 arranged on the top end of the transparent glass cover 2 can be used for assisting mixing, and the external sensor can be connected to the sensor external interface 19 arranged on the right front end of the base plate 1, so as to monitor fluid parameters such as flow rate and pressure.

[0036] With reference to Figure 4 , the anti-skid assembly comprises two mounting grooves 10, which are arranged on the bottom end of the base plate 1; two double-sided adhesive layers 11, which are arranged on the inner top walls of the two mounting grooves 10; and two anti-skid rubber plates 12, which are fixedly connected to the bottom ends of the two double-sided adhesive layers 11.

[0037] Specifically, the double-sided adhesive layer 11 arranged between the mounting groove 10 and the anti-skid rubber plate 12 can firmly adhere the anti-skid rubber plate 12 to the mounting groove 10 to prevent the anti-skid rubber plate 12 from falling off.

[0038] With reference to Figure 2 , Figure 3 and Figure 4 , the base plate 1 is fixedly connected with a micro driver 13, and the output end of the micro driver 13 is fixedly connected with a vortex generator 14; one end of the capillary channel 8, which is away from the meandering channel 7, is connected to the sample outlet 9; and the vortex generator 14 is arranged in the mixing pool 5.

[0039] Specifically, the vortex generator 14 arranged in the middle of the mixing pool 5 can be used for generating vortex and disturbance in the fluid to increase the mixing efficiency.

[0040] It should be noted that (the vortex generator 14, the electromagnetic driver 16 and the micro controller 18) are all known or can be known to the related technical field professionals, and therefore will not be described here.

[0041] Working principle: the device can introduce fluid into the mixing pool 5 through the sampling interface 3 and the sampling interface 4, and install the vortex generator 14 in the middle of the mixing pool 5, which can be used to generate vortex and disturbance in the fluid, increase the mixing efficiency, then through the mixing flow channel 6, the fluid enters the inside of the connected serpentine channel 7, and finally flows out from the sampling interface 9 through the capillary channel 8, so that the different fluids can complete the mixing when flowing in the channel, thereby improving the uniformity of fluid mixing;

[0042] At the same time, the sensor external interface 19 opened on the right side of the front end of the bottom plate 1 can be connected with an external sensor, so as to monitor the fluid parameters such as flow rate, pressure, etc., and two installation grooves 10 are opened at the bottom end of the bottom plate 1, and a double-sided adhesive layer 11 is arranged on the inner top wall of the two installation grooves 10, and the antiskid rubber plate 12 is fixed in the installation groove 10 through the double-sided adhesive layer 11, so as to enhance the friction force of the bottom end of the bottom plate 1, thereby preventing the sliding of the bottom plate 1 from affecting the mixing of the fluid.

[0043] Finally, it should be pointed out that: the above only for the preferred embodiments of the utility model, and does not limit the utility model, although the utility model is described in detail with reference to the foregoing embodiments, for the person skilled in the art, it still can modify the technical scheme recorded in the foregoing each embodiment, or equivalent replacement to part of technical features, any modification, equivalent replacement, improvement etc. made within the spirit and principles of the utility model, should be contained in the protection scope of the utility model.

Claims

1. A high-stability microfluidic mixer comprising a base plate (1), characterized in that: The top end of the bottom plate (1) is provided with a transparent glass cover (2), the left end rear side of the transparent glass cover (2) is provided with a mixing assembly; The mixing assembly comprises a sample injection interface I (3), the sample injection interface I (3) is opened in the left end rear side of the transparent glass cover (2), the left end front side of the transparent glass cover (2) is provided with a sample injection interface II (4), the middle left side of the top end of the bottom plate (1) is provided with a mixing pool (5), the right end of the mixing pool (5) is communicated with a mixing flow channel (6), the other end of the mixing flow channel (6) is communicated with a meandering channel (7), the other end of the meandering channel (7) is communicated with a capillary channel (8), the rear end of the bottom plate (1) is provided with a sample outlet interface (9), and the bottom end of the bottom plate (1) is provided with an anti-skid assembly.

2. The high stability microfluidic mixer of claim 1, wherein: The anti-skid assembly comprises two mounting grooves (10), the two mounting grooves (10) are both opened in the bottom end of the bottom plate (1), the inner top wall of the two mounting grooves (10) is provided with a double-sided adhesive layer (11), and the bottom end of the double-sided adhesive layer (11) is fixedly connected with an anti-skid rubber plate (12).

3. The high stability microfluidic mixer of claim 1, wherein: The right side of the sample injection interface I (3) is communicated with the left side rear end of the mixing pool (5) through a communication pipeline, and the right side of the sample injection interface II (4) is communicated with the left side front end of the mixing pool (5) through a communication pipeline.

4. The high stability microfluidic mixer of claim 1, wherein: The bottom end of the bottom plate (1) is fixedly connected with a micro driver (13), and the output end of the micro driver (13) is fixedly connected with an eddy current generator (14).

5. The high stability microfluidic mixer of claim 4, wherein: The end of the capillary channel (8) away from the meandering channel (7) is communicated with the sample outlet interface (9), and the eddy current generator (14) is arranged in the mixing pool (5).

6. The high stability microfluidic mixer of claim 1, wherein: The top end of the transparent glass cover (2) is provided with an escape port (15).

7. The high stability microfluidic mixer of claim 1, wherein: The right side of the bottom plate (1) is fixedly connected with an electromagnetic driver (16), and the output end of the electromagnetic driver (16) is fixedly connected with an electromagnetic plate (17).

8. The high stability microfluidic mixer of claim 1, wherein: The top right side of the bottom plate (1) is fixedly connected with a microcontroller (18), and the front right side of the bottom plate (1) is provided with a sensor external interface (19).

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