Magnetic control device for magnetic particle distribution in blood vessel

Abstract

The utility model relates to the technical field of medical instruments, in particular to a magnetic control device for magnetic particle distribution in blood vessels, which comprises a plurality of fastening plates arranged in a surrounding manner, the adjacent fastening plates are adjustably and fixedly connected through movable plates, rectangular openings are formed in the fastening plates, and the bottom ends of the rectangular openings and the fastening plates form through holes; a magnet carrying plate is installed in the rectangular opening, a plurality of through holes are formed in the magnet carrying plate, magnetic induction assemblies are installed in the through holes, the center line of each magnetic induction assembly faces the center of the surrounding fastening plate, a flat cable connecting port is formed in the side, away from the rectangular opening, of the magnet carrying plate, and the flat cable connecting port penetrates through the through hole and extends out of the fastening plate; after the flat cable connector is connected with a power supply, the magnetic induction assembly generates a magnetic field to change the distribution state of the magnetic particles in the fastening plate; the magnetic control device adjusts distribution of magnetic particles in the blood vessel by controlling electromagnetic changes of the magnetic induction assembly, directional distribution of the magnetic particles in regular and irregular areas of the intima under a magnetic field is achieved, and precise targeting of complex diseased regions is met.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically to a magnetic control device for the distribution of magnetic particles in blood vessels. Background Technology

[0002] Vascular diseases such as atherosclerosis have become a major cause of global disease burden. Existing treatments include intravenous drug delivery and interventional drug delivery via medical devices. However, traditional treatments suffer from low drug concentration accumulation at the lesion site, high loss rates during delivery, and low rates of targeted vascular metastasis. In recent years, with the development of life sciences and micro / nano fabrication technologies, drug-loaded magnetic particles have seen rapid advancements. Leveraging their controllable navigation capabilities and morphological diversity, they can enter lesions that are difficult to access in the human body via minimally invasive methods, achieving long-term regulation. However, due to the relatively complex blood flow environment in the human body, including high blood flow velocity and interference from blood cells, the delivery of drug-loaded magnetic particles in the circulatory system faces challenges such as relatively slow movement speed, long delivery distance, and precise targeting of the lesion site. These issues limit the application of drug-loaded magnetic particles.

[0003] In existing technologies, traditional permanent magnet systems lack flexible control methods and operational space, and cannot meet the precise driving requirements of magnetic particles in complex vascular lesion sites. Utility Model Content

[0004] To address the shortcomings of existing technologies, this invention provides a magnetic control device for the distribution of magnetic particles within blood vessels. The device is fitted around the periphery of the lesion site in the human body. By controlling the electromagnetic changes of the magnetic sensing components, the distribution of magnetic particles within the blood vessel is adjusted, achieving precise targeting of the lesion site under a magnetic field. During installation, the distance between adjacent fastening plates is adjusted by sliding them to ensure a closer fit between the fastening plates and the lesion site. A scale is installed on the top of the movable plate; by observing the scale and adjusting the spacing, the magnetic plate can be positioned appropriately, facilitating precise guidance of the magnetic particles.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A magnetic control device for the distribution of magnetic particles within blood vessels includes several surrounding fastening plates. Adjacent fastening plates are adjustablely fixedly connected by movable plates. Each fastening plate has a rectangular opening, the bottom of which forms a through hole. A magnetic carrier plate is installed inside the rectangular opening, and the magnetic carrier plate has several through holes. Magnetic sensing components are installed inside these through holes, with the centerline of the magnetic sensing components facing the center of the surrounding fastening plates. A cable connection port is located on the side of the magnetic carrier plate away from the rectangular opening, extending through the through holes to the outside of the fastening plate. When the cable connection port is powered on, the magnetic sensing components generate a magnetic field that alters the distribution of magnetic particles within the fastening plates.

[0007] As a preferred technical solution of this utility model, a guide groove is provided on the movable plate, and two knob bolts are installed in the same guide groove. The two knob bolts are screwed into the corresponding threaded holes to connect the movable plate and two adjacent fastening plates.

[0008] As a preferred technical solution of this utility model, the magnetic sensing component is an electromagnet, the core of the electromagnet is made of silicon steel, and the electromagnet coil is electrically connected to the ribbon cable connector.

[0009] As a preferred technical solution of this utility model, there are 4 fastening plates, and the winding directions of the electromagnet coils on adjacent fastening plates are opposite.

[0010] As a preferred embodiment of this utility model, the total length of the electromagnet is 2-3 cm, and the diameter of the iron core is 2-3 cm;

[0011] As a preferred technical solution of this utility model, the electromagnet coil is made of copper-aluminum alloy and the coil is covered with insulating material.

[0012] As a preferred technical solution of this utility model, the top two ends of the magnetic plate extend outward to form a support plate, and countersunk holes are opened on the support plate. Bolts are installed in the countersunk holes and fixedly connected to the fastening plate.

[0013] As a preferred technical solution of this utility model, a scale is provided on the top of the movable plate;

[0014] As a preferred embodiment of this invention, the size of the through hole is smaller than the bottom size of the magnetic plate;

[0015] As a preferred technical solution of this utility model, the fastening plate, movable plate, knob bolt, magnetic plate, support plate, ribbon cable connector and bolt are all made of carbon fiber.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] 1. In this utility model, a sleeve structure is formed by several fastening plates and fitted around the lesion site of the human body. The inner diameter is adjusted by a movable plate and then fixed. After the magnetic sensing component on the magnetic plate is powered on, the magnetic sensing component generates a magnetic field. The magnetic control device adjusts the distribution of magnetic particles in the blood vessel by controlling the electromagnetic changes of the magnetic sensing component, so as to realize the directional distribution of magnetic particles in regular and irregular areas of the vascular intima under the magnetic field, so as to meet the precise targeting of complex lesion sites.

[0018] 2. In this utility model, when installing the magnetic control device, the movable plate and the fastening plate can be slidably connected by loosening the knob bolt. The adjacent fastening plates can be slid to adjust the distance between them so that the fastening plates fit the diseased part of the human body more closely. After the position is adjusted, the movable plate and the adjacent fastening plates are fixedly connected by tightening the knob bolt. A scale is set on the top of the movable plate to measure the distance between two adjacent fastening plates. By accurately adjusting the distance, the magnetic plate can be placed in a suitable position, which is conducive to the precise guidance of magnetic particles. Attached Figure Description

[0019] Figure 1 This is a three-dimensional schematic diagram of the overall structure of this utility model.

[0020] Figure 2 This is a three-dimensional schematic diagram of the disassembled structure of the fastening plate and the magnet plate of this utility model. Figure 1 ;

[0021] Figure 3 This is a three-dimensional schematic diagram of the disassembled structure of the fastening plate and the magnet plate of this utility model. Figure 2 ;

[0022] In the diagram: Fastening plate-10; Movable plate-11; Guide groove-12; Knob bolt-13; Ruler-14; Magnetic plate-15; Support plate-16; Through hole-17; Magnetic induction component-18; Rectangular opening-19; Threaded hole-20; Through hole-21; Cable connector-22. Detailed Implementation

[0023] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

[0024] Contents not described in detail in this specification are existing technologies known to those skilled in the art. In the description of this utility model, it should be understood that terms such as "center," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," and "counterclockwise," indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings and are used only for the convenience of describing this utility model and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as limiting this utility model. Furthermore, terms such as "first," "second," and "third," etc., are used only to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0025] like Figures 1-3As shown, a magnetic control device for the distribution of magnetic particles within a blood vessel includes several surrounding fastening plates 10. Adjacent fastening plates 10 are adjustablely fixedly connected by movable plates 11. Each fastening plate 10 has a rectangular opening 19, the bottom of which forms a through hole 21 with the fastening plate 10. A magnetic carrier plate 15 is installed inside the rectangular opening 19. The magnetic carrier plate 15 has several through holes 17, and a magnetic sensing component 18 is installed inside each through hole 17. The centerline of the magnetic sensing component 18 faces the center of the surrounding fastening plates 10. A cable connection port 22 is provided on the side of the magnetic carrier plate 15 away from the rectangular opening 19. The cable connection port 22 extends through the through holes 21 to the outside of the fastening plate 10. When the cable connection port 22 is powered on, the magnetic sensing component 18 generates a magnetic field that alters the distribution of magnetic particles within the fastening plate 10.

[0026] In this invention, several fastening plates 10 are arranged to form a sleeve structure, which is fitted around the lesion site on the human body. The inner diameter is adjusted by the movable plate 11 before being fixed. After the magnetic sensing component 18 on the magnetic plate 15 is powered on, the magnetic sensing component 18 generates a magnetic field. By controlling the electromagnetic changes of the magnetic sensing component 18, the distribution of magnetic particles inside the blood vessel is adjusted, so as to realize the directional distribution of magnetic particles in regular and irregular areas of the vascular endothelium under the magnetic field, which meets the precise targeting of complex lesion sites.

[0027] The fastening plate 10 is arc-shaped, with its curved surface conforming to the human body. When the fastening plate 10 is closed, it is fitted over the outside of the diseased part of the human body.

[0028] Furthermore, the movable plate 11 is provided with a guide groove 12, and two knob bolts 13 are installed in the same guide groove 12. The two knob bolts 13 are screwed into the corresponding threaded holes 20 to connect the movable plate 11 and the two adjacent fastening plates 10.

[0029] When installing this magnetic control device, the movable plate 11 and the fastening plate 10 can be slidably connected by loosening the knob bolt 13 (or the knob bolt 13 can be removed). The fastening plate 10 is then placed on the lesion site of the human body, and the knob bolt 13 is tightened. The adjacent distance is adjusted by sliding the adjacent fastening plates 10 to make the fastening plates 10 fit the lesion site of the human body more closely. After the position is adjusted, the movable plate 13 is fixedly connected to the adjacent fastening plates 10 by tightening the knob bolt 13.

[0030] Furthermore, the magnetic sensing component 18 is an electromagnet, the core of which is made of silicon steel, and the electromagnet coil is electrically connected to the ribbon cable connector 22.

[0031] The magnetic induction component 18 is a solenoid, a Helmholtz coil, a Maxwell coil, or an electromagnet, preferably an electromagnet.

[0032] Solenoids have the characteristics of good uniformity, small size, and high magnetic field. They can generate AC and DC magnetic fields, and the current and magnetic field have a good linear relationship.

[0033] Helmholtz coils have a large uniform region volume, allowing for ample space to operate and are easy to use. They can generate one-dimensional, two-dimensional, and three-dimensional combined magnetic fields (circular or rectangular), and can also provide AC and DC magnetic fields, with a good linear relationship between current and magnetic field.

[0034] Maxwell coils can generate a large-scale, uniform magnetic field at the center of the coil, with better uniformity. They are available in a wide space, easy to operate, and can generate both AC and DC magnetic fields, with good linearity between the magnetic field and the current.

[0035] The electromagnet uses a single-pole electromagnet, which forms a closed circuit through a coil and an iron core to generate a uniform high magnetic field. The air gap of the magnetic field is adjustable, and it has good rigidity.

[0036] Silicon steel is preferred for the core of an electromagnet because it has high permeability and can generate a greater magnetic induction intensity under the same magnetic field strength.

[0037] Silicon steel has low hysteresis loss, meaning it consumes less magnetic energy during changes in the magnetic field. This characteristic helps reduce energy consumption and heat generation in electromagnetic devices.

[0038] Silicon steel has a relatively high resistivity, which helps to reduce eddy current losses and further reduce energy consumption.

[0039] Furthermore, there are four fastening plates 10, and the winding directions of the electromagnet coils on adjacent fastening plates 10 are opposite.

[0040] Figure 1 As shown, there are four fastening plates 10. The winding directions of the electromagnet coils on adjacent fastening plates 10 are opposite, while the winding directions of the electromagnet coils on opposite fastening plates are the same. When the electromagnet is powered on, the magnetic force generated by the electromagnetic coil can be controlled by adjusting the electromagnet's on / off state to regulate the electromagnetic changes and form a stable magnetic field. Under the action of the magnetic field, the magnetic particles are directionally distributed in regular and irregular areas of the vascular endothelium and move towards the lesion site, causing the carried drugs to converge towards the lesion site.

[0041] Furthermore, the total length of the electromagnet is 2-3 cm, and the diameter of the iron core is 2-3 cm. Preferably, the total length of the electromagnet is 3 cm, and the diameter of the iron core is 3 cm.

[0042] Furthermore, the electromagnet coil is made of copper-aluminum alloy, and the coil is covered with insulating material.

[0043] Copper-aluminum alloys combine the electrical conductivity of copper and aluminum. In electromagnet coils, copper-aluminum alloys can effectively transmit current, reduce energy loss, and improve the working efficiency and performance of electromagnets.

[0044] Copper-aluminum alloy coils are lighter than pure copper coils. Lightweight design not only helps reduce the overall weight of the electromagnet, improving portability, but also reduces energy consumption and cost. Lightweight design is particularly important in electromagnet applications that require mobility or frequent operation.

[0045] Copper-aluminum alloys are not magnetic and will not affect the magnetic field in the magnetic control device of this invention.

[0046] Furthermore, the top two ends of the magnetic plate 15 extend outward to form a support plate 16, and countersunk holes are provided on the support plate 16. Bolts are installed in the countersunk holes to fix and connect with the fastening plate 10.

[0047] The countersunk holes on the support plate 16 are connected to the fastening plate 10 by bolts, which facilitates disassembly, inspection and maintenance in the future.

[0048] Furthermore, a scale 14 is provided on the top of the movable plate 11.

[0049] The scale 14 is used to measure the distance between two adjacent fastening plates 10. By precisely adjusting the distance, the four magnetic plates 15 can be positioned in a compatible manner, which is beneficial for guiding the magnetic particles.

[0050] Furthermore, the size of the through hole 21 is smaller than the bottom size of the magnetic plate 15.

[0051] A cable connector 22 is inserted through the through hole 21. The cable connector 22 is surrounded by the bottom of the magnetic plate 15, and the magnetic plate 15 provides support for the cable connector 22.

[0052] One end of the ribbon cable connector 22 is connected to several magnetic induction components 18. The ribbon cable connector 22 is connected to a power supply and a switch. The number or position of the magnetic induction components 18 connected is controlled by the switch, which helps to control the magnitude and direction of the magnetic field generated by the magnetic plate 15, and further adjust the position of the magnetic particles.

[0053] Furthermore, the materials of the fastening plate 10, movable plate 11, knob bolt 13, magnetic plate 15, support plate 16, ribbon cable connector 22 and bolt are all carbon fiber.

[0054] The above components are made of carbon fiber and are not magnetic. Therefore, they will not affect the magnetic field in the magnetic control device of this utility model.

[0055] This utility model is illustrated through the above embodiments, but it is not limited to these embodiments, meaning that it does not necessarily depend on them for implementation. Those skilled in the art should understand that all related improvements to this utility model fall within its protection and disclosure scope.

Claims

1. A magnetic control device for the distribution of magnetic particles within blood vessels, comprising several surrounding fastening plates (10), characterized in that, The adjacent fastening plates (10) are fixedly and adjustablely connected by a movable plate (11). A rectangular opening (19) is provided on the fastening plate (10), and the bottom end of the rectangular opening (19) forms a through hole (21) with the fastening plate (10). A magnetic plate (15) is installed inside the rectangular opening (19). Several through holes (17) are provided on the magnetic plate (15). A magnetic sensing component (18) is installed inside the through hole (17). The center line of the magnetic sensing component (18) faces the center of the surrounding fastening plate (10). A ribbon cable connection port (22) is provided on the side of the magnetic plate (15) away from the rectangular opening (19). The ribbon cable connection port (22) extends through the through hole (21) to the outside of the fastening plate (10). After the ribbon cable connection port (22) is connected to the power supply, the magnetic sensing component (18) generates a magnetic field to change the distribution state of the magnetic particles in the fastening plate (10).

2. The magnetic control device for the distribution of magnetic particles within blood vessels according to claim 1, characterized in that, The movable plate (11) is provided with a guide groove (12), and two knob bolts (13) are installed in the same guide groove (12). The two knob bolts (13) are screwed into the corresponding threaded holes (20) to connect the movable plate (11) and the two adjacent fastening plates (10).

3. The magnetic control device for the distribution of magnetic particles in blood vessels according to claim 1, characterized in that, The magnetic sensing component (18) is an electromagnet, the core of which is made of silicon steel, and the electromagnet coil is electrically connected to the ribbon cable connector (22).

4. The magnetic control device for the distribution of magnetic particles in blood vessels according to claim 3, characterized in that, There are four fastening plates (10), and the electromagnet coils on adjacent fastening plates (10) are wound in opposite directions.

5. The magnetic control device for the distribution of magnetic particles in blood vessels according to claim 3, characterized in that, The electromagnet is 2-3 cm long and the iron core is 2-3 cm in diameter.

6. The magnetic control device for the distribution of magnetic particles in blood vessels according to claim 5, characterized in that, The electromagnet coil is made of copper-aluminum alloy, and the coil is covered with insulating material.

7. The magnetic control device for the distribution of magnetic particles in blood vessels according to claim 1, characterized in that, The top two ends of the magnetic plate (15) extend outward to form a support plate (16). A countersunk hole is opened on the support plate (16), and a bolt is installed in the countersunk hole to fix it to the fastening plate (10).

8. The magnetic control device for the distribution of magnetic particles in blood vessels according to claim 1, characterized in that, A ruler (14) is provided on the top of the movable plate (11).

9. The magnetic control device for the distribution of magnetic particles in blood vessels according to claim 1, characterized in that, The size of the through hole (21) is smaller than the bottom size of the magnetic plate (15).

10. The magnetic control device for the distribution of magnetic particles in blood vessels according to any one of claims 1-9, characterized in that, The fastening plate (10), movable plate (11), knob bolt (13), magnetic plate (15), support plate (16), ribbon cable connector (22) and bolt are all made of carbon fiber.

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