Chromatographic column convenient for flow control

Abstract

The utility model discloses a chromatographic column convenient to control flow, which comprises a chromatographic column, a flow sensor and a flow regulator, a liquid outlet pipe is arranged in the middle of the bottom of the chromatographic column, a pipe penetrating groove is arranged in the middle of the flow sensor, the liquid outlet pipe is wrapped by the pipe penetrating groove, the flow regulator is arranged at the tail end of the liquid outlet pipe, and the flow regulator comprises a control device and a regulating valve. The regulating valve comprises a liquid inlet and a liquid outlet, a cavity is arranged between the liquid inlet and the liquid outlet, and a butterfly valve is arranged in the cavity. The flow sensor is additionally arranged on the liquid outlet pipe at the bottom of the chromatographic column, so that the flow volume flowing into the chromatographic column can be accurately monitored, and the butterfly valve is informed to be closed when the flow volume reaches a set value; a flow regulator is additionally arranged at the tail end of the liquid outlet pipe, and a liquid outlet connecting valve of the flow regulator is provided with the flow regulator, so that the flow velocity can be regulated; the control panel can control opening and closing of the butterfly valve, accurate control over flow is achieved, accurate control over the flow volume and the flow speed of the chromatographic column can be achieved, and the flow control device is suitable for popularization.

Description

TECHNICAL FIELD

[0001] The utility model relates to chromatography column technical field more specifically, it is a kind of chromatography column that flow is controlled conveniently. BACKGROUND

[0002] Column chromatography technology main principle is according to the distribution coefficient of each component in sample mixture in stationary phase and mobile phase, component is separated by repeatedly distributing for many times.Chromatography operation, first, insoluble matrix is filled in cylindrical tube, forms a stationary phase.Sample is added to column, elution is carried out using special solvent, and solvent constitutes mobile phase.In the process that sample is eluted from column, according to the distribution coefficient of each component in sample mixture in stationary phase and mobile phase, component is separated by repeatedly distributing for many times.The speed of silica gel chromatography process directly influences the separation effect of chromatography column.The flow control method of existing chromatography column is connected with latex hose at liquid outlet end, the tightness degree of latex tube is adjusted by hemostatic forceps or clamp, or the valve of polytetrafluoroethylene is connected at liquid outlet end, and the flow rate is adjusted by adjusting the size of valve opening and closing, the existing structure cannot control flow rate and flow well and accurately, so that the result cannot accurately show chromatography effect, thereby affecting experimental data, in view of this, the present application provides a kind of chromatography column that flow is controlled conveniently to solve this problem, by liquid outlet additional flow control device, accurate flow monitoring is carried out to enter chromatography column, including flow rate and flow, which helps to improve chromatography quality and obtain accurate experimental results.

[0003] In order to effectively control the flow of chromatography column and improve the chromatography quality, Chinese patent application, publication number: CN211097655U, discloses a chromatography device, the utility model includes chromatography column, chromatography column cover, multi-hole gasket, cone, drain pipe and flow control valve, chromatography column cover has hollow connection part;Chromatography column cover is arranged at the upper end of chromatography column and is connected with the upper end of chromatography column by detachable mode;Chromatography column is provided with one or more multi-hole gaskets;The lower end of chromatography column is connected with cone;Drain pipe is connected with the bottom of cone;And flow control valve is arranged on drain pipe, and flow control valve is water faucet type control valve.The utility model discloses a flow control valve, which can control the flow of liquid flowing into the chromatography column and improve the chromatography effect.

[0004] The scheme still has some deficiencies in application, because chromatography operation is a very meticulous work, the flow and flow rate of liquid injected into chromatography column will affect the chromatography result, so accurate control is required, otherwise it is easy to affect the chromatography result due to improper flow and flow rate control, based on this, the structure of chromatography column liquid injection device needs to be improved, the chromatography column liquid injection device should be able to monitor and control the flow and flow rate, ensure the accuracy of flow and flow rate, and maximize the chromatography quality. UTILITY MODEL CONTENT

[0005] The utility model discloses a chromatography column convenient to control flow, and its main purpose is to overcome the above -mentioned insufficient and shortcoming of prior art.

[0006] The utility model discloses a technical scheme as follows:

[0007] A chromatography column convenient to control flow, including chromatography column, flow inductor and flow regulator, the middle of chromatography column bottom is equipped with the liquid outlet pipe, the middle of flow inductor is equipped with the pipe slot, and the pipe slot is wrapped with the liquid outlet pipe, and the flow regulator is installed at the end of the liquid outlet pipe, and the flow regulator includes upper control device and lower regulating valve, the regulating valve includes liquid inlet and liquid outlet, and the middle of liquid inlet and liquid outlet is equipped with cavity body, and the cavity body is built-in butterfly valve.

[0008] Further, the flow regulator is provided with a loading rack, and the loading rack is provided with a roller at the bottom.

[0009] Further, the control device includes a display screen and a control panel, and the butterfly valve is connected with the control panel.

[0010] Further, the flow inductor is provided with a data connection line, and the data connection line is connected with the control panel.

[0011] Further, the liquid outlet is provided with a connecting valve, and a flow rate regulator is installed on the connecting valve, and the flow rate regulator is connected with the control panel.

[0012] Further, the chromatography column is provided with a moving frame.

[0013] Through the above description of the utility model, compared with the prior art, the utility model has the advantages of:

[0014] The utility model firstly adds a flow inductor through the liquid outlet pipe at the bottom of the chromatography column, the flow volume flowing into the chromatography column can be monitored through the flow inductor, and when the flow reaches the set value, the information is transmitted to the control panel to control the butterfly valve to be closed, so that the flow is accurately controlled; then, a flow regulator is added at the end of the liquid outlet pipe, and a flow regulator is arranged on the connecting valve of the liquid outlet of the flow regulator, so that the flow rate can be adjusted, the flow rate is prevented from being too large or too small to affect the chromatography operation, and the chromatography quality is further improved; finally, when the flow reaches the set value, the butterfly valve can be stopped through the control panel, and the flow and the flow rate can be known in real time through the display screen, which is self-evident, the utility model is designed ingeniously, the flow volume and the flow rate of the chromatography column can be accurately controlled, the chromatography quality is effectively improved, the experimental results are guaranteed, and the utility model is suitable for promotion. BRIEF DESCRIPTION OF DRAWINGS

[0015] Fig. 1It is the structural schematic diagram of the utility model.

[0016] Fig. 2 It is the structural schematic diagram of the utility model flow sensor.

[0017] Fig. 3 It is the structural schematic diagram of the utility model regulating valve.

[0018] Fig. 4 It is the front view structural schematic diagram of regulating valve. DETAILED DESCRIPTION

[0019] The specific embodiments of the utility model are further illustrated below with reference to the accompanying drawings.

[0020] As Figs. 1 to 4 shown, a kind of chromatography column for controlling flow, including chromatography column 1, flow sensor 2 and flow regulator 3, the bottom middle of the chromatography column 1 is equipped with liquid outlet pipe 4, the middle of the flow sensor 2 is equipped with pipe slot 5, this pipe slot 5 is adaptively equipped with the liquid outlet pipe 4, the flow regulator 3 is installed in the end of the liquid outlet pipe 4, the flow regulator 3 includes upper control device 6 and lower regulating valve 7, the regulating valve 7 includes liquid inlet 71 and liquid outlet 72, the middle of the liquid inlet 71 and the liquid outlet 72 is equipped with cavity body 8, butterfly valve 9 is built-in in this cavity body 8.

[0021] Further, the flow regulator 3 is equipped with loading rack 10, the bottom of the loading rack 10 is equipped with gyro wheel 11.

[0022] Further, the control device 6 includes display screen 61 and control panel 62, the butterfly valve 9 and the control panel 62 are controlled connection.

[0023] Further, the flow sensor 2 is equipped with data connection line 21, and the data connection line 21 is controlled connection with the control panel 62.

[0024] Further, the liquid outlet 72 is equipped with connecting valve 12, and flow rate regulator 13 is installed on the connecting valve 12, and the flow rate regulator 13 is controlled connection with the control panel 62.

[0025] Further, the chromatography column 1 is equipped with moving frame 14.

[0026] [EMBODIMENT]

[0027] First, the liquid inlet 71 of the flow regulator 3 is connected with the external liquid container, the liquid outlet 72 is connected with the liquid outlet pipe 4, then, the butterfly valve 9 is started through the control panel 62, the liquid enters the cavity body 8 from the liquid inlet 71 and enters the liquid outlet pipe 4 through the liquid outlet 72, then enters the chromatography column 1 through the flow sensor 2, in the liquid inlet process, the flow rate is adjusted through the flow regulator 13 on the connecting valve 12 and is displayed through the display screen 61, the flow volume can be accurately known through the flow sensor 2 and is also displayed through the display screen 61, through the setting, the flow rate and the flow volume can be known, and corresponding adjustment can be carried out according to the requirement, finally, when the flow volume reaches the set value, the flow sensor 2 transmits information to the control panel 62, the butterfly valve 9 is controlled to be closed through the control panel 62, and the accurate flow control is realized.

[0028] Compared with the prior art, the utility model has the advantages that:

[0029] The utility model discloses first through the liquid outlet pipe of chromatography column bottom adds flow sensor, can monitor the flow volume of flowing into chromatography column through flow sensor, and when the flow volume reaches the set value, will information transmission to the control panel control butterfly valve and closes, realizes the accurate control of flow volume, then, adds flow regulator at the end of liquid outlet pipe, is equipped with flow regulator on the valve of flow regulator liquid outlet, can adjust the flow rate of flow volume, avoids that flow rate is too big or too small and influences chromatography operation, further improves chromatography quality, finally, when the flow volume reaches the set value, can stop through the control panel to butterfly valve, can know flow volume and flow rate in real time through the display screen, at a glance, the utility model discloses clever design can realize chromatography column to the accurate control of flow volume and flow rate, effectively improves chromatography quality, guarantees the experimental result, is fit for promotion.

[0030] The above is merely a specific embodiment of the utility model, but the design concept of the utility model is not limited to this, and any non-substantial improvement of the utility model using this concept should belong to the act of infringing the protection scope of the utility model.

Claims

1. A chromatography column facilitating control of flow, characterized by: Including chromatographic column, flow sensor and flow regulator, the chromatographic column bottom middle is equipped with liquid outlet pipe, the flow sensor middle is equipped with pipe slot, the pipe slot is suitably wrapped the liquid outlet pipe, the flow regulator is installed in the liquid outlet pipe end, the flow regulator includes upper control device and lower regulating valve, the regulating valve includes liquid inlet and liquid outlet, the liquid inlet and the liquid outlet middle is equipped with cavity body, the cavity body is built-in butterfly valve.

2. The chromatography column for easy flow control according to claim 1, characterized in that: The flow regulator is equipped with loading frame, and the loading frame bottom is equipped with roller.

3. The chromatography column for facilitating flow control of claim 1, wherein: The control device includes a display screen and a control panel, and the butterfly valve and the control panel are control connected.

4. The chromatography column for facilitating flow control of claim 3, wherein: The flow sensor is equipped with data connection line, and the data connection line is control connected with the control panel.

5. The chromatography column for facilitating flow control of claim 3, wherein: The liquid outlet is equipped with connection valve, and the flow rate regulator is installed on the connection valve, and the flow rate regulator is control connected with the control panel.

6. The chromatography column for facilitating flow control of claim 1, wherein: The chromatographic column is equipped with moving frame.

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