Sampling and storing device for tumors
By combining liquid nitrogen cooling with temperature sensors, the problem of traditional tumor sampling and preservation devices being unable to maintain low temperatures for extended periods and monitor temperatures in real time has been solved, achieving high-quality preservation of tumor samples and accurate test results.
Patent Information
- Application Number
- CN202520566814.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-28
- Publication Date
- 2026-02-24
- Estimated Expiration
- 2035-03-28
AI Technical Summary
Traditional tumor sampling and preservation methods are difficult to maintain a low-temperature environment for extended periods, affecting sample viability and integrity, and the inability to monitor temperature in real time leads to inaccurate test results.
Liquid nitrogen is used as a refrigerant. The liquid nitrogen is evenly distributed into the refrigeration chamber through a multi-channel guide tube. The temperature is monitored in real time by a temperature sensor, and the liquid nitrogen supply is precisely controlled by a control panel to ensure that the samples are stored within a suitable temperature range.
This technology enables precise cryopreservation of tumor samples, improving sample preservation quality and stability, and ensuring the accuracy of test results.
Smart Images

Figure CN223929351U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of sample preservation technology, and in particular to a sample preservation device for tumors. Background Technology
[0002] In the fields of cancer research and clinical treatment, accurate analysis and diagnosis of tumor samples are crucial, and obtaining high-quality tumor samples and preserving them properly are the foundation for subsequent research and treatment.
[0003] Traditional methods for tumor sampling and preservation often involve temporary storage using ice packs or refrigerators. This not only makes it difficult to control the temperature but also to maintain the required low-temperature environment for extended periods, affecting the activity and integrity of the tumor samples and consequently the accuracy of detection and analysis results. Furthermore, the inability to monitor the temperature of the sample storage environment in real time makes it difficult to detect abnormal temperatures promptly, which can easily lead to sample damage. Therefore, we propose a tumor sampling and preservation device to address these issues. Utility Model Content
[0004] The purpose of this invention is to address the shortcomings of existing technologies that use ice packs or refrigerators to preserve tumor samples, which result in difficulty in temperature control and short preservation time, affecting sample activity and integrity. Therefore, this invention proposes a tumor sampling and preservation device.
[0005] To achieve the above objectives, the present invention adopts the following technical solution:
[0006] A tumor sampling and preservation device includes a housing with a sealing cover hinged to its top. A control panel is fixedly mounted on one side of the housing. Two fixing posts are fixedly mounted on the inner walls of the two adjacent sides of the housing. A shelf is fixedly connected to the top of the four fixing posts. The shelf has multiple refrigeration chambers for storing sample boxes. Liquid inlets are located at the bottom of the multiple refrigeration chambers. A lithium battery is fixedly mounted on the bottom inner wall of the housing and electrically connected to the control panel. The device also includes:
[0007] The refrigeration unit is located on the bottom inner wall of the cabinet and is used to refrigerate and preserve samples in multiple refrigeration chambers.
[0008] Multiple monitoring components are installed in the corresponding refrigeration chambers to monitor the temperature inside the refrigeration chambers.
[0009] In one possible design, the refrigeration assembly includes a liquid nitrogen tank, which is fixedly mounted on the bottom inner wall of the housing. A multi-channel guide pipe is fixedly mounted on the bottom inner wall of the housing. One end of the liquid nitrogen tank has a liquid outlet, which is connected to the multi-channel guide pipe via a first connecting pipe. Multiple liquid inlets are connected to the multi-channel guide pipe via second connecting pipes. The bottom inner walls of multiple refrigeration chambers are provided with guide grooves that communicate with the liquid inlets. Electric flow valves are mounted on the first connecting pipe and the multiple second connecting pipes. The multiple electric flow valves are electrically connected to the lithium battery and the control panel.
[0010] In one possible design, a booster pump is fixedly installed on the bottom inner wall of the housing, and an air inlet pipe is fixedly connected to the other end of the liquid nitrogen tank. The air outlet of the booster pump is connected to the air inlet pipe through a third connecting pipe. A solenoid valve is installed on the third connecting pipe, and the solenoid valve is electrically connected to the lithium battery and the control panel.
[0011] In one possible design, the monitoring component includes temperature sensors fixed to the inner wall of the refrigeration chamber, and all temperature sensors are electrically connected to the lithium battery and the control panel.
[0012] In one possible design, each of the multiple refrigeration cavities is provided with a cover plate at its opening, and the inner wall of each refrigeration cavity is provided with symmetrical grooves. The cover plate is rotatably connected to one of the grooves, and two locking blocks are fixed on both sides of the cover plate. The two locking blocks are engaged with the inner walls of the other groove.
[0013] In one possible design, a sealing strip is fixedly embedded in the top of the box, heat insulation plates are provided on the four fixed posts below the placement rack, and a ventilation slot is provided on one side of the sealing cover.
[0014] In this application, firstly, the sealing cover is opened, the sample box containing the tumor sample is placed into the refrigeration chamber on the placement rack, and then the cover is closed so that the locking block and the groove are engaged, thus confining the sample box containing the tumor sample within the refrigeration chamber and providing a certain sealing effect to the refrigeration chamber.
[0015] Next, the device is started via the control panel. The lithium battery powers the entire device, starts the booster pump and opens the solenoid valve on the third connecting pipe. The booster pump pressurizes the liquid nitrogen tank through the third connecting pipe and the air inlet pipe. At the same time, the electric flow valves on the first connecting pipe and multiple second connecting pipes are opened. Under pressure, the liquid nitrogen in the liquid nitrogen tank enters the multi-channel guide pipe through the first connecting pipe, and then enters each refrigeration chamber from the liquid inlet through the second connecting pipe. The guide grooves on the inner wall of the bottom of the refrigeration chamber can make the liquid nitrogen more evenly distributed, thereby refrigerating and preserving the sample.
[0016] Temperature sensors in each refrigeration compartment monitor the temperature in real time and transmit the temperature data to the control panel. Operators can view the temperature of each refrigeration compartment on the control panel. When the temperature in a refrigeration compartment is higher than the set value, the corresponding electric flow valve can be controlled through the control panel to increase the supply of liquid nitrogen to lower the temperature; when the temperature is lower than the set value, the supply of liquid nitrogen will be reduced.
[0017] During the liquid nitrogen evaporation process, the generated gas can be discharged from the chamber through the ventilation slot on one side of the sealed cover to prevent gas accumulation. The sealing strip on the top of the chamber and the heat insulation plate on the fixed column can effectively reduce the entry of external heat and ensure the low temperature environment inside the chamber.
[0018] Beneficial effects: In this utility model, the sampling and preservation device for tumors, by setting up a refrigeration component and using liquid nitrogen as a refrigerant, distributes liquid nitrogen evenly into each refrigeration chamber through a multi-channel guide pipe and multiple second connecting pipes, thereby achieving precise refrigeration and preservation of the sample and effectively improving the preservation quality of the sample.
[0019] In this invention, the sampling and preservation device for tumors is equipped with multiple monitoring components and uses temperature sensors to monitor the temperature inside the cold storage chamber in real time, ensuring that the sample is always within a suitable preservation temperature range, thereby further improving the preservation effect of the sample.
[0020] In this utility model, the sampling and preservation device for tumors has a cover plate at the opening of the refrigeration chamber. The cover plate has a locking structure of a locking block and a groove, which can effectively seal the refrigeration chamber, reduce the entry of external heat and the evaporation of liquid nitrogen, and further improve the stability and reliability of sample preservation.
[0021] In this invention, a refrigeration component using liquid nitrogen as a refrigerant is used to evenly distribute the liquid nitrogen into each refrigeration chamber, thereby achieving precise cold storage of samples. Multiple monitoring components can monitor the temperature inside the refrigeration chamber in real time, ensuring that the samples are always within a suitable storage temperature range. The cover plate at the opening of the refrigeration chamber can effectively seal the refrigeration chamber, reducing the entry of external heat and the evaporation of liquid nitrogen, further improving the stability and reliability of sample preservation. Attached Figure Description
[0022] Figure 1 This is a three-dimensional structural schematic diagram of a tumor sampling and preservation device proposed in this utility model.
[0023] Figure 2 This is a three-dimensional structural diagram of the box of a tumor sampling and preservation device proposed in this utility model when the box is opened.
[0024] Figure 3This is a partial cross-sectional three-dimensional structural diagram of the housing of a tumor sampling and preservation device proposed in this utility model.
[0025] Figure 4 This is a top-view three-dimensional structural diagram of the internal structure of the sample preservation device for tumors proposed in this utility model.
[0026] Figure 5 This is a partial three-dimensional structural diagram of a placement rack for a tumor sampling and preservation device proposed in this utility model.
[0027] Figure 6 This is a three-dimensional structural diagram of the cover plate of a tumor sampling and preservation device proposed in this utility model.
[0028] In the diagram: 1. Box body; 2. Sealing cover; 3. Control panel; 4. Fixing column; 5. Placement rack; 501. Refrigeration chamber; 502. Flow guide channel; 503. Liquid inlet; 6. Liquid nitrogen tank; 7. Multi-way flow guide pipe; 8. Electric flow valve; 9. Air inlet pipe; 10. Booster pump; 11. Cover plate; 111. Locking block; 12. Sealing strip; 13. Heat insulation plate; 14. Ventilation slot; 15. Temperature sensor; 16. Lithium battery. Detailed Implementation
[0029] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.
[0030] Example 1: Refer to Figure 1-6 A sampling and preservation device includes a housing 1, the top of which is hinged to a sealing cover 2. This hinged connection allows the sealing cover 2 to be easily opened and closed, facilitating the insertion and removal of samples. A control panel 3 is fixedly installed on one side of the housing 1, allowing operators to operate and control various functions of the device.
[0031] Two fixing posts 4 are fixedly installed on the inner walls of the four adjacent sides of the housing 1. A shelf 5 is fixedly connected to the top of each of the four fixing posts 4. The shelf 5 has multiple refrigeration chambers 501 for storing sample boxes, and liquid inlets 503 are located at the bottom of each refrigeration chamber 501. A lithium battery 16 is fixedly installed on the bottom inner wall of the housing 1. The lithium battery 16 is electrically connected to the control panel 3, providing power to the electrical components of the entire device.
[0032] The device also includes a refrigeration unit and multiple monitoring units. The refrigeration unit is located on the bottom inner wall of the housing 1 and is used to refrigerate and preserve samples in multiple refrigeration chambers 501. Multiple monitoring units are located in the corresponding refrigeration chambers 501 to monitor the temperature inside the refrigeration chambers 501 and ensure that the samples are preserved in a suitable low-temperature environment.
[0033] The refrigeration assembly includes a liquid nitrogen tank 6, which is fixedly installed on the bottom inner wall of the housing 1 as a storage container for liquid nitrogen. A multi-way guide pipe 7 is also fixedly installed on the bottom inner wall of the housing 1. One end of the liquid nitrogen tank 6 has a liquid outlet, which is connected to the multi-way guide pipe 7 via a first connecting pipe. The liquid inlets 503 of multiple refrigeration chambers 501 are all connected to the multi-way guide pipe 7 via second connecting pipes, allowing liquid nitrogen to flow from the liquid nitrogen tank 6 through the multi-way guide pipe 7 into each refrigeration chamber 501. The bottom inner walls of multiple refrigeration chambers 501 are each provided with a guide groove 502 connected to the liquid inlet 503. The guide groove 502 allows the flowing liquid nitrogen to be more evenly distributed at the bottom of the refrigeration chamber 501, improving the refrigeration effect. Electric flow valves 8 are installed on the first connecting pipe and multiple second connecting pipes, and the multiple electric flow valves 8 are electrically connected to the lithium battery 16 and the control panel 3. Operators can adjust the opening of the electric flow valve 8 through the control panel 3 to precisely control the flow rate of liquid nitrogen into each refrigeration chamber 501.
[0034] A booster pump 10 is fixedly installed on the bottom inner wall of the housing 1. An air inlet pipe 9 is fixedly connected to the other end of the liquid nitrogen tank 6. The outlet of the booster pump 10 is connected to the air inlet pipe 9 through a third connecting pipe. A solenoid valve is installed on the third connecting pipe, which is electrically connected to the lithium battery 16 and the control panel 3. The working status of the booster pump 10 and the solenoid valve can be controlled by the control panel 3, which can adjust the pressure in the liquid nitrogen tank 6 to ensure that liquid nitrogen can be smoothly delivered to each refrigeration chamber 501.
[0035] The monitoring component includes a temperature sensor 15, which is fixedly installed on the inner wall of the refrigeration chamber 501 and electrically connected to the lithium battery 16 and the control panel 3. The temperature sensor 15 monitors the temperature inside the refrigeration chamber 501 in real time and transmits the temperature data to the control panel 3, allowing operators to monitor the temperature of each refrigeration chamber 501 in real time on the control panel 3.
[0036] Each of the multiple refrigeration chambers 501 has a cover plate 11 at its opening. The inner wall of each refrigeration chamber 501 has symmetrically formed grooves. The cover plate 11 is rotatably connected to one of these grooves. Two locking blocks 111 are fixed to both sides of the cover plate 11, and these two locking blocks 111 engage with the inner walls of the other groove. This structure allows the cover plate 11 to be easily opened and closed, while also reducing heat transfer and liquid nitrogen evaporation when closed.
[0037] This application can be used in the field of sample preservation technology, or in other fields applicable to this application.
[0038] Example 2: Reference Figure 1-4 An improvement upon Embodiment 1: A tumor sampling and preservation device, applied in the field of sample preservation technology, features a sealing strip 12 fixedly embedded in the top of the housing 1. When the sealing cover 2 is closed, the sealing strip 12 enhances the airtightness of the housing 1, preventing external heat from entering. Heat insulation plates 13 are installed on the four fixed posts 4 below the placement rack 5, reducing heat transfer from the bottom of the housing 1 to the placement rack 5 and the refrigeration chamber 501. A ventilation slot 14 is provided on one side of the sealing cover 2 to discharge gases generated by liquid nitrogen evaporation, preventing gas accumulation inside the housing.
[0039] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.
Claims
1. A sampling and preservation device for tumors, comprising a housing (1), wherein a sealing cover (2) is hinged to the top of the housing (1) via a hinge shaft, a control panel (3) is fixedly provided on one side of the housing (1), two fixing posts (4) are fixedly provided on the inner walls of the two adjacent sides of the housing (1), a placement rack (5) is fixedly connected to the top of the four fixing posts (4), the placement rack (5) has multiple refrigeration chambers (501) for storing sample boxes, the bottom of the multiple refrigeration chambers (501) has a liquid inlet (503), a lithium battery (16) is fixedly provided on the inner wall of the bottom of the housing (1), the lithium battery (16) is electrically connected to the control panel (3), characterized in that, The device also includes: The refrigeration component is located on the bottom inner wall of the box (1) and is used to refrigerate and preserve samples in multiple refrigeration chambers (501). Multiple monitoring components are installed in the corresponding cold storage chamber (501) to monitor the temperature inside the cold storage chamber (501).
2. The tumor sampling and preservation device according to claim 1, characterized in that, The refrigeration assembly includes a liquid nitrogen tank (6), which is fixedly installed on the bottom inner wall of the box (1). A multi-channel guide pipe (7) is fixedly installed on the bottom inner wall of the box (1). One end of the liquid nitrogen tank (6) is provided with a liquid outlet, and the liquid outlet is connected to the multi-channel guide pipe (7) through a first connecting pipe. Multiple liquid inlets (503) are connected to the multi-channel guide pipe (7) through second connecting pipes. Multiple refrigeration chambers (501) are provided with guide grooves (502) on the bottom inner wall that are connected to the liquid inlets (503). Electric flow valves (8) are provided on the first connecting pipe and multiple second connecting pipes. Multiple electric flow valves (8) are electrically connected to the lithium battery (16) and the control panel (3).
3. The tumor sampling and preservation device according to claim 2, characterized in that, A booster pump (10) is fixedly installed on the bottom inner wall of the box (1). An air inlet pipe (9) is fixedly connected to the other end of the liquid nitrogen tank (6). The outlet of the booster pump (10) is connected to the air inlet pipe (9) through a third connecting pipe. A solenoid valve is installed on the third connecting pipe. The solenoid valve is electrically connected to the lithium battery (16) and the control panel (3).
4. A tumor sampling and preservation device according to claim 3, characterized in that, The monitoring component includes a temperature sensor (15), which is fixedly installed on the inner wall of the refrigeration chamber (501). The temperature sensor (15) is electrically connected to the lithium battery (16) and the control panel (3).
5. A tumor sampling and preservation device according to claim 4, characterized in that, Each of the multiple refrigeration chambers (501) is provided with a cover plate (11) at its opening. The inner wall of each refrigeration chamber (501) is provided with symmetrical grooves. The cover plate (11) is rotatably connected to one of the grooves. Two locking blocks (111) are fixed on both sides of the cover plate (11), and the two locking blocks (111) are engaged with the inner walls of the other groove on both sides.
6. A tumor sampling and preservation device according to claim 1, characterized in that, A sealing strip (12) is fixedly embedded in the top of the box (1), and a heat insulation plate (13) is provided on the four fixed columns (4) below the placement rack (5). A ventilation groove (14) is provided on one side of the sealing cover (2).