Sample pretreatment device for blood detection

Abstract

The utility model provides a sample pretreatment device for blood detection, which relates to the technical field of laboratory equipment and comprises a vortex mixer for oscillating and swirling a blood sample reagent in a reagent tube; the auxiliary frame is mounted on the vortex mixer, and a semicircular-arc-shaped frame rod surrounding the periphery of a vibration disc of the vortex mixer is arranged on the auxiliary frame; and the sliding sleeve seat is arranged on the frame rod. Due to the design of the semi-arc-shaped frame rods on the auxiliary frame, the reagent tubes are ensured to be uniformly distributed around the vibration disc of the vortex mixer, and the stability of the reagent tubes in the vibration process is also greatly improved. By means of the improvement, the shaking and instability phenomena possibly occurring when a test tube is held by a hand for vortex mixing in the prior art are effectively avoided, and therefore full mixing and uniformity of a blood sample reagent are guaranteed.

Description

Technical Field

[0001] This utility model relates to the field of laboratory equipment technology, and in particular to a sample pretreatment device for blood testing. Background Technology

[0002] Sample pretreatment is a crucial step in the HPLC detection of mitotane, directly affecting the accuracy and reliability of subsequent assays. Traditional sample pretreatment methods often involve hand-held vortexing of the test tube; however, this approach has revealed a series of problems in practice.

[0003] First, when vortexing test tubes by hand, the limited stability and control of the human hand often make it difficult to ensure the uniformity and stability of the reagent tube during the vortexing process. This can not only lead to insufficient mixing of blood sample reagents, affecting the accuracy of test results, but also pose safety hazards due to the shaking and instability of the reagent tube.

[0004] Secondly, the traditional hand-held vortex mixing method requires a high level of skill from the operator, demanding extensive experience and a good feel for the material. However, in practice, due to differences in skill levels among operators, it is often difficult to guarantee the consistency and repeatability of each experiment. This not only increases the uncertainty of the experiment but may also affect the analysis and judgment of the experimental results.

[0005] In addition, hand-held vortex mixing of test tubes also presents problems such as cumbersome operation and high labor intensity. Operators need to hold the test tubes for a long time to perform vortex mixing, which can easily lead to fatigue and discomfort, and may also affect work efficiency and experimental progress. Utility Model Content

[0006] This utility model relates to a sample pretreatment device for blood testing. It aims to successfully replace the traditional method of manually holding test tubes and vortexing by introducing an auxiliary frame, a sliding sleeve seat, and an insert seat. This improves the accuracy and controllability of the experiment, reduces the difficulty of operation and fatigue, and brings significant technological innovation and practical benefits to the field of blood analysis.

[0007] In a first aspect, this utility model provides a sample pretreatment device for blood testing, specifically comprising: a vortex mixer for oscillating and vortexing blood sample reagents in a reagent tube; an auxiliary frame mounted on the vortex mixer, the auxiliary frame having a semi-circular rod surrounding the vibrating disc of the vortex mixer; a sliding sleeve mounted on the rod; an insert seat, the upper end of which is hinged to the sliding sleeve; and a sleeve mounted on the insert seat for inserting reagent tubes.

[0008] Optionally, a positioning and fixing hole is horizontally provided at the position where the sliding sleeve seat is installed on the frame rod, and the sliding sleeve seat is fixed in position by being inserted into the positioning and fixing hole by a positioning bolt.

[0009] Optionally, a hanging plate is fixed vertically downward at the bottom of the sliding sleeve seat.

[0010] Optionally, the back of the insert seat is fixed with an arc-shaped bent rod as the rotation axis of the upper hinge. The bent rod passes through the hanging plate, and a spring is fitted on the bent rod on the back side of the hanging plate. The spring provides the insert seat with a pulling force that always moves closer to the hanging plate. The insert seat is provided with a clamp fixing sleeve, and the sleeve and the clamp are further fixed by fixing bolts.

[0011] Optionally, the sleeve is provided with a clamping bolt, the inner end of which is used to hold the reagent tube in place. Adjusting the position of the reagent tube in the sleeve changes the angle between the reagent tube and the vortex mixer vibrating plate. A viewing window is provided on the side wall of the sleeve for observing and adjusting the reagent tube.

[0012] Optionally, the size of the sleeve can be changed according to the size of the reagent tube.

[0013] This invention provides a sample pretreatment device for blood testing, which has the following beneficial effects:

[0014] First, by ingeniously combining an auxiliary frame with a vortex mixer, the device achieves stable support and efficient mixing of reagent tubes. The semi-circular rod design on the auxiliary frame not only ensures the uniform distribution of reagent tubes around the vortex mixer's vibrating plate but also significantly improves the stability of the reagent tubes during oscillation. This improvement effectively avoids the shaking and instability that may occur when traditionally mixing test tubes by hand, thus ensuring thorough mixing and homogeneity of blood sample reagents.

[0015] Furthermore, the positioning and fixing holes of the sliding sleeve and the support rod provide users with great flexibility. By adjusting the position of the sliding sleeve on the support rod, users can easily change the distance and angle between the reagent tube and the vortex mixer to adapt to different experimental needs. This design not only improves the accuracy and controllability of the experiment but also greatly simplifies the operation process, making the placement and adjustment of reagent tubes more convenient.

[0016] Most importantly, the hinged installation of the insert holder and the sliding sleeve, along with the introduction of a spring, allows the insert holder to rotate freely within a certain range, enabling the reagent tube to be angled according to different experimental needs. Simultaneously, the continuous tension of the spring ensures that the insert holder and the reagent tube on it remain stable, leaning towards the hanging plate when no external force is applied. This not only enhances the stability of the reagent tube but also reduces fatigue caused by holding the test tube by hand.

[0017] Furthermore, by changing the sleeves of different sizes, the device can easily adapt to reagent tubes of various specifications, thus meeting the needs of diverse experiments. The clamping bolts and viewing window design on the sleeves provide users with convenient reagent tube position adjustment and a visual operation experience, making the entire vortex mixing process more intuitive and controllable.

[0018] In summary, the blood sample pretreatment device of this invention, through the ingenious combination of the auxiliary frame, sliding sleeve seat and insert seat, successfully replaces the traditional method of hand-held test tube mixing. This not only improves the accuracy and controllability of the experiment, but also greatly reduces the difficulty of operation and fatigue, bringing significant technological innovation and practical benefits to the field of blood analysis. Attached Figure Description

[0019] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings of the embodiments will be briefly described below.

[0020] The accompanying drawings described below are only related to some embodiments of the present invention and are not intended to limit the scope of the present invention.

[0021] In the attached diagram:

[0022] Figure 1 A schematic diagram of the overall axial view structure of this utility model is shown;

[0023] Figure 2 A schematic diagram of the auxiliary frame structure of this utility model is shown in axial view.

[0024] Figure 3 The diagram shows an axial view of the reagent tube and sleeve in a phase-separated state according to the present invention.

[0025] List of reference numerals

[0026] 1. Vortex mixer;

[0027] 2. Auxiliary frame; 201. Frame pole; 2011. Positioning and fixing holes;

[0028] 3. Sliding sleeve seat; 301. Positioning bolt; 302. Hanging plate;

[0029] 4. Insert bracket; 401. Bend rod; 402. Spring; 403. Clamp; 404. Fixing bolt;

[0030] 5. Sleeve; 501. Tightening bolt; 502. Viewing window;

[0031] 6. Reagent tubes. Detailed Implementation

[0032] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the described embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0033] Example 1: Please refer to Figures 1 to 3 :

[0034] This utility model proposes a sample pretreatment device for blood testing, comprising: a vortex mixer 1 for oscillating and vortexing the blood sample reagent in the reagent tube 6; an auxiliary frame 2 installed on the vortex mixer 1, the auxiliary frame 2 having a semi-circular rod 201 surrounding the vibrating plate of the vortex mixer 1; a sliding sleeve 3 installed on the rod 201; an insert seat 4, the upper end of the insert seat 4 being hinged to the sliding sleeve 3; and a sleeve 5 installed on the insert seat 4 for inserting the reagent tube 6.

[0035] The mounting rod 201 has a horizontally positioned fixing hole 2011 at the location where the sliding sleeve seat 3 is installed. The sliding sleeve seat 3 is fixed in position by being inserted into the fixing hole 2011 with a positioning bolt 301.

[0036] Among them, the bottom of the sliding sleeve seat 3 is vertically fixed with a hanging plate 302.

[0037] Among them, the back of the insert 4 is fixed with an arc-shaped bent rod 401 with the upper hinge as the rotation axis. The bent rod 401 passes through the hanging plate 302. A spring 402 is installed on the bent rod 401 on the back side of the hanging plate 302. The spring 402 provides the insert 4 with a pulling force that always moves closer to the hanging plate 302. The insert 4 is provided with a clamp 403 to fix the sleeve 5. The sleeve 5 and the clamp 403 are further fixed by fixing bolts 404.

[0038] The sleeve 5 is provided with a clamping bolt 501. The inner end of the clamping bolt 501 is used to hold the reagent tube 6. Adjusting the position of the reagent tube 6 in the sleeve 5 changes the angle between the reagent tube 6 and the vibrating plate of the vortex mixer 1. A viewing window 502 is provided on the side wall of the sleeve 5 for observing and adjusting the reagent tube 6.

[0039] In Example 2, based on Example 1, the size of the sleeve 5 is changed according to the size of the reagent tube 6.

[0040] The working principle of this embodiment:

[0041] The core component of the device is the vortex mixer 1, which is responsible for generating oscillations and vortex motions to thoroughly mix the blood sample reagents in the reagent tubes 6. To effectively support and manage these reagent tubes, an auxiliary frame 2 is designed, which is directly mounted on the vortex mixer 1 and has a semi-circular support rod 201 arranged around the vibrating disc of the vortex mixer. This design ensures that the reagent tubes remain stable and uniformly stressed during oscillation.

[0042] The sliding sleeve seat 3 can be flexibly installed on the support rod 201 through the horizontally opened positioning and fixing holes 2011. The position of the sliding sleeve seat 3 is precisely adjusted and fixed by the positioning bolts 301. This design allows users to adjust the position of the reagent tube according to actual needs to adapt to different operational requirements. The bottom of the sliding sleeve seat 3 is provided with a hanging plate 302, which not only enhances the stability of the structure, but also provides a support point for the hinged installation of the insert seat 4.

[0043] The cartridge holder 4 is connected to the sliding sleeve seat 3 via an upper hinge, allowing it to rotate within a certain range. An arc-shaped bent rod 401 located on the back of the cartridge holder passes through the hanging plate 302 and is continuously tensioned by a spring 402, ensuring that the cartridge holder 4 (and its sleeve 5 and reagent tube 6) remain close to the hanging plate 302 when no external force is applied. This design helps maintain the stability of the reagent tube during oscillation and allows the user to easily adjust the angle of the reagent tube as needed.

[0044] Sleeve 5 is mounted on insert base 4 for inserting reagent tube 6. The design of sleeve 5 fully considers flexibility and adaptability: by tightening bolt 501, the user can adjust the position of the reagent tube within the sleeve, thereby changing the angle between the reagent tube and the vortex mixer's vibrating plate to accommodate different mixing needs. Furthermore, a viewing window 502 on the side wall of the sleeve allows the user to observe the mixing process within the reagent tube, ensuring visualization of the operation.

[0045] It is worth mentioning that the size of sleeve 5 can be changed according to the size of reagent tube 6, which greatly enhances the versatility and practicality of the device. Whether it is a standard reagent tube or a test tube of a special size, it can be adapted by changing the sleeve of the corresponding size, thereby meeting diverse experimental needs.

[0046] The following points should be noted in this article:

[0047] 1. The accompanying drawings of this utility model embodiment only involve the structure involved in this utility model embodiment; other structures can refer to general designs.

[0048] 2. Where there is no conflict, the embodiments of this utility model and the features in the embodiments can be combined with each other to obtain new embodiments.

[0049] The above are merely specific embodiments of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the scope of the claims.

Claims

1. A sample pretreatment device for blood testing, comprising: A vortex mixer (1) is used to oscillate and vortex the blood sample reagent in the reagent tube (6); characterized in that an auxiliary frame (2) is installed on the vortex mixer (1), and the auxiliary frame (2) is provided with a semi-circular rod (201) surrounding the vibrating disk of the vortex mixer (1); a sliding sleeve seat (3) is installed on the rod (201); an insert seat (4) is hinged at the upper end of the insert seat (4) on the sliding sleeve seat (3); and a sleeve (5) is installed on the insert seat (4) for inserting the reagent tube (6).

2. The sample pretreatment device for blood testing according to claim 1, characterized in that, A horizontal positioning and fixing hole (2011) is provided at the position where the sliding sleeve seat (3) is installed on the frame rod (201). The sliding sleeve seat (3) is fixed in position by being inserted into the positioning and fixing hole (2011) by a positioning bolt (301).

3. The sample pretreatment device for blood testing according to claim 1, characterized in that, The bottom of the sliding sleeve seat (3) is vertically fixed with a hanging plate (302).

4. The sample pretreatment device for blood testing according to claim 3, characterized in that, The back of the insert (4) is fixed with an arc-shaped bent rod (401) with the upper hinge as the axis of rotation. The bent rod (401) passes through the hanging plate (302). A spring (402) is fitted on the bent rod (401) on the back side of the hanging plate (302). The spring (402) provides the insert (4) with a pulling force that always moves closer to the hanging plate (302). The insert (4) is provided with a clamp (403) to fix the sleeve (5). The sleeve (5) and the clamp (403) are further fixed by fixing bolts (404).

5. The sample pretreatment device for blood testing according to claim 1, characterized in that, The sleeve (5) is provided with a clamping bolt (501), the inner end of which is used to hold the reagent tube (6). Adjusting the position of the reagent tube (6) in the sleeve (5) changes the angle between the reagent tube (6) and the vibrating plate of the vortex mixer (1). A viewing window (502) is provided on the side wall of the sleeve (5) for observing and adjusting the reagent tube (6).

6. The sample pretreatment device for blood testing according to claim 1, characterized in that, The size of the sleeve (5) is changed according to the size of the reagent tube (6).

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