Auxiliary device suitable for electroacupuncture intervention of acupuncture points on head and back of laboratory mouse

Abstract

The utility model belongs to the field of biological experiment instruments, and discloses an auxiliary device suitable for electroacupuncture intervention of acupuncture points on the head and the back of an experimental mouse. The auxiliary device comprises an experiment box and a bridle, wherein the experiment box is provided with a moving cavity for the laboratory mouse to move; the band is annular and is sleeved and tightened on the abdomen of the laboratory mouse, so that acupuncture points on the head and the back can be completely exposed in front of researchers, and the electric needles can conveniently pierce the acupuncture points on the head and the back of the laboratory mouse. The electric needle wire penetrates into the binding ring of the binding belt and is connected with the electric needle penetrating into the acupuncture points of the head and the back of the laboratory mouse, so that the electric needle wire is fixedly attached to the back of the laboratory mouse through the binding belt, and the laboratory mouse can be prevented from scratching and biting to affect the experiment. After the experimental mouse with the bridle is put into the experimental box, the experimental box can provide a limited environment in which the experimental mouse can move in a small range for the experimental mouse, so that the stimulation and environmental pressure on the experimental mouse are reduced, the anxiety or depression probability of the experimental mouse can be reduced, and the experimental mouse can be effectively intervened for a long time.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of biological experiment instrument, especially to an auxiliary device suitable for head and back acupoint electro-acupuncture intervention of experimental mouse. BACKGROUND

[0002] Modern acupoint electro-acupuncture stimulation experiment often takes experimental mouse as the research object, because the physiology of experimental mouse is highly similar to human, and the experimental mouse is relatively small, more suitable as the research object, and easier to study the mechanism of action of corresponding acupoint and meridian. However, the activity of experimental mouse is not dominated by human consciousness, and it is easy to scratch when acupuncture is performed on the back of the head, and the electro-acupuncture falls off, resulting in inaccurate experimental results, so a corresponding fixing device is needed to assist the experimental mouse to receive acupuncture intervention on the back of the head.

[0003] At present, there are mainly two kinds of experimental mouse fixing devices known:

[0004] One of them is in the form of a mouse coat, which is divided into a conical upper half for covering the head of the experimental mouse and a cylindrical lower half for binding, and the experimental mouse is in a state of being wrapped all over when using this device, which is not conducive to acupuncture of the acupoint on the back of the head and observation of the state of the experimental mouse. Moreover, the experimental mouse will tear the mouse coat to seek escape due to tension and pain, so that its state is in a long-term state of tension and unrest, which is not conducive to long-term intervention.

[0005] The other is a cylindrical fixator, which includes a cylindrical limiting cylinder, and the experimental mouse can drill into the limiting cylinder to wrap and fix the body of the experimental mouse, but this device will cover more acupoints on the back of the head, and will restrict the mouse in a narrow space, which is easy to cause additional pressure to the experimental mouse, and long-term restriction and depression may cause anxiety or depression of the experimental mouse, affecting the experimental results, and is also not suitable for long-term intervention.

[0006] Therefore, it is necessary to design a new auxiliary device suitable for long-term acupuncture of acupoints on the head and back of the experimental mouse, to avoid causing great pressure and external stimulation to the experimental mouse, so that it can assist long-term intervention in the experimental mouse's conscious state. CONTENT OF THE UTILITY MODEL

[0007] The utility model aims at providing an auxiliary device suitable for head and back acupoint electro-acupuncture intervention of experimental mouse, which can effectively intervene the experimental mouse for a long time, and make the experimental results more reliable.

[0008] To achieve this purpose, the utility model adopts the following technical solutions:

[0009] The utility model relates to an auxiliary device suitable for electric acupuncture intervention of experimental mouse head and back acupoints, including experimental box and band, the experimental box has the activity chamber for the experimental mouse to walk, the band is annular and is connected to the abdomen of the experimental mouse, and the electric acupuncture wire is arranged in the restraint ring of the band and is connected with the electric acupuncture wire inserted into the experimental mouse head back acupoint, so as to be fixedly attached to the back of the experimental mouse through the band.

[0010] As preferred, the band comprises a first restraint part, a second restraint part and an elastic member, wherein:

[0011] One end of the first restraint part is connected to one end of the second restraint part, a waist-shaped sliding hole is arranged at the middle position of the first restraint part, and an installation groove communicating with the waist-shaped sliding hole is arranged inside the other end of the first restraint part;

[0012] The other end of the second restraint part is inserted into the waist-shaped sliding hole after being bent, so that the first restraint part and the second restraint part can jointly form the restraint ring;

[0013] The elastic member is arranged in the installation groove, one end of the elastic member is connected to the groove wall of the installation groove, the other end of the elastic member extends into the waist-shaped sliding hole and is connected to the other end of the second restraint part, and the elastic member is used for providing elastic force for the second restraint part.

[0014] As preferred, the elastic member is a plastic spring.

[0015] As preferred, a limiting sliding channel is arranged in the sidewall of the waist-shaped sliding hole along the axis direction of the first restraint part, and the other end of the second restraint part is provided with a protrusion, which is slidably arranged in the limiting sliding channel.

[0016] As preferred, the experimental box is provided with a transparent part.

[0017] As preferred, the experimental box comprises a box body and a box cover, the box body is provided with the activity chamber, the box cover is detachably connected to the box body, and the box cover and / or the box body is provided with the transparent part.

[0018] As preferred, the sidewall of the box body is provided with a first threading hole and a second threading hole, the first threading hole is used for threading the electric acupuncture wire, and the second threading hole is used for threading the other end of the second restraint part.

[0019] As preferred, the box cover is provided with a breathable hole.

[0020] As preferred, the band is provided with a sensor, which is used for detecting the pressure of the band on the experimental mouse.

[0021] And / or, the inductor is used for detecting the body temperature of the experimental mouse.

[0022] And / or, the inductor is used for detecting the heart rate of the experimental mouse.

[0023] As preferred, the inner annular surface of the restraint ring is attached with several flexible pads.

[0024] The auxiliary device for electric acupuncture intervention of experimental mouse head and back acupoints provided by the embodiment has the following beneficial effects: the experimental box has a moving chamber for the experimental mouse to move; the bandage is annular and is sleeved and tightened on the abdomen of the experimental mouse, so that the acupoints of the head and back can be completely exposed in front of the researchers, and thus the electric acupuncture can be conveniently inserted into the acupoints of the head and back of the experimental mouse. The electric acupuncture wire is arranged in the restraint ring of the bandage and is connected with the electric acupuncture inserted into the acupoints of the head and back of the experimental mouse, so as to be fixedly attached to the back of the experimental mouse through the bandage, thereby preventing the experimental mouse from scratching and biting to affect the experiment. In addition, after the experimental mouse with the bandage is placed in the experimental box, the experimental box can provide a limited but small-magnitude-movable environment for the experimental mouse, thereby reducing the stimulation and environmental pressure on the experimental mouse, allowing the experimental mouse to get rid of the long-term restraint and depressing environment, helping to reduce the probability of anxiety or depression of the experimental mouse, and thus the experimental mouse can be effectively intervened for a long time, and the reliability of the experimental results is ensured. BRIEF DESCRIPTION OF DRAWINGS

[0025] Figure 1 is a structural schematic view of the experimental box provided by the embodiment of the utility model;

[0026] Figure 2 is a structural schematic view of the bandage when it is unfolded;

[0027] Figure 3 is Figure 2 is a local enlarged view of A in FIG. 4;

[0028] Figure 4 is a structural schematic view of the bandage after the elastic member is hidden.

[0029] In the drawings:

[0030] 1, experimental box; 101, moving chamber; 11, box body; 111, first threading hole; 112, second threading hole; 12, box cover;

[0031] 2, bandage; 21, first restraint part; 211, waist-shaped sliding hole; 2111, limiting sliding way; 212, mounting groove; 2121, communication hole; 22, second restraint part; 221, protrusion; 23, elastic member. DETAILED DESCRIPTION

[0032] The utility model will be further described in detail below in combination with the drawings and embodiments. It can be understood that the specific embodiments described herein are only used to explain the utility model and not to limit the utility model. In addition, it should be noted that only the parts related to the utility model are shown in the drawings for ease of description, not all the structures.

[0033] In the description of the utility model, unless otherwise explicitly specified and limited, the terms "connected", "connected", "fixed" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or it can be integrated; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the internal communication of two elements or the interaction relationship of two elements. For ordinary skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific circumstances.

[0034] In the utility model, unless otherwise explicitly specified and limited, the first feature "on" or "below" the second feature can include that the first and second features are in direct contact, or the first and second features are not in direct contact but are in contact through another feature between them. Moreover, the first feature "on", "above" and "on" the second feature includes that the first feature is directly above and obliquely above the second feature, or only indicates that the horizontal height of the first feature is higher than that of the second feature. The first feature "below", "below" and "below" the second feature includes that the first feature is directly below and obliquely below the second feature, or only indicates that the horizontal height of the first feature is less than that of the second feature.

[0035] In the description of the embodiment, the terms "up", "down", "right", "left" and other orientation or position relationship are based on the orientation or position relationship shown in the drawings, only for the convenience of description and simplification of operation, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, therefore cannot be understood as a limitation of the utility model. In addition, the terms "first", "second" are only used to distinguish in description and have no special meaning.

[0036] The technical scheme provided by the utility model will be introduced below in combination with the drawings and specific embodiments.

[0037] In combination with Figures 1 to 4As shown, the embodiment provides an auxiliary device suitable for electric acupuncture intervention on the acupoints of the head and back of experimental mice, which comprises an experimental box 1 and a belt 2, wherein the experimental box 1 has a movable chamber 101 for small movement of experimental mice; and the belt 2 is bendable to form a ring-shaped restraint ring. In use, the researcher holds the tail of the experimental mouse with one hand to make the experimental mouse in a forward climbing state, and holds the belt 2 on the head of the experimental mouse with the other hand. After the experimental mouse is drilled into the restraint ring, the belt 2 is pulled to the abdomen of the experimental mouse to be tightened, so that the acupoints of the head and back of the experimental mouse can be completely exposed in front of the researcher, and the electric acupuncture can be conveniently inserted into the acupoints of the head and back of the experimental mouse. Preferably, in the embodiment, the belt 2 is sleeved on the groin of the experimental mouse.

[0038] Subsequently, the electric acupuncture wire is inserted from the back of the experimental mouse into the restraint ring and clamped on the electric acupuncture in the insertion direction to realize the conductive connection of the electric acupuncture wire and the electric acupuncture, and the electric acupuncture is fixed and attached to the back of the experimental mouse through the belt 2 to prevent the experimental mouse from scratching and biting to affect the experiment. Finally, the experimental mouse is placed in the experimental box 1, which can provide a limited but small movement environment for the experimental mouse. Compared with the existing fixing devices such as mouse clothes and cylindrical fixators, the stimulation and environmental pressure on the experimental mouse can be reduced, the experimental mouse can get rid of the long-term restraint and depressed environment, which helps to reduce the probability of anxiety or depression of the experimental mouse, and the experimental mouse can be effectively intervened for a long time, thereby ensuring the smoothness of the experiment and the accuracy and reliability of the results.

[0039] It should be noted that the auxiliary device provided by the embodiment can further comprise a fixing table provided with a clamping device for limiting the movement of the limbs and the swinging of the head of the experimental mouse, so that after the belt 2 is tied on the experimental mouse, the experimental mouse is stably fixed on the fixing table by means of the clamping device, and then the researcher inserts the needle into the acupoints of the head and back of the experimental mouse. By providing the fixing table, not only the electric acupuncture can be accurately and stably inserted into the acupoints of the head and back, but also the researcher can avoid pressing the experimental mouse with his hand, thereby reducing the operation burden of the researcher.

[0040] Optionally, the fixing table can be separately arranged with the experimental box 1, when the acupuncture of the acupoints on the head and back of the experimental mouse is completed, the experimental mouse is released from the fixing table and placed into the experimental box 1. In addition, the fixing table can also be slidingly arranged at the bottom of the experimental box 1, when the experimental mouse is not placed into the experimental box 1, the fixing table is located in the experimental box 1, after the experimental mouse is bound with the belt 2 and placed into the experimental box 1, the experimental mouse is fixed on the fixing table through the clamping device on the fixing table, and then the acupuncture of the acupoints on the head and back of the experimental mouse is performed, after the acupuncture is completed, the experimental mouse is released from the fixing table, and finally the fixing table is extracted from the experimental box 1. In this way, the auxiliary device provided by the utility model not only has the beneficial effect of conveniently fixing the experimental mouse and ensuring the accuracy of the acupuncture of the acupoints, but also has the advantage of avoiding long-term restraint of the experimental mouse, thereby ensuring the safety and reliability of the experiment.

[0041] Optionally, in other embodiments, a medical double-sided adhesive tape, a silica gel adhesive tape or a polyurethane foam adhesive tape and the like having low adhesion can also be attached at the connection between the electric needle and the head and back of the experimental mouse, so that the electric needle can be stably acupunctured on the acupoint, the electric needle is prevented from being shaken off by the experimental mouse, and the pulling of the hair can be reduced, thereby being removed without damaging the skin.

[0042] Specifically, in the embodiment, as shown in the Figure 1 The box cover 12 is detachably connected to the box body 11. Through the above arrangement, when the experimental mouse is not placed into the box body 11, the box cover 12 can be detachably connected to the box body 11, so as to ensure the cleanliness inside the box body 11, reduce the pollution of the external environment, thereby providing a clean and comfortable environment for the experimental mouse, and also facilitating the cleaning of the box after use. When the experimental mouse is placed into the box body 11, the arrangement of the box cover 12 can prevent the mouse from jumping out of the box body 11, or avoid the experimental mouse from being bumped and interfered by external objects, thereby further preventing the experimental mouse from being subjected to additional stress stimulation.

[0043] Further, the box cover 12 is hingedly connected with the box body 11, so as to facilitate the opening and closing of the box body 11, and facilitate the operation and use.

[0044] It should be noted that the experimental box 1 is provided with a transparent part, so that the researcher can observe the state of the experimental mouse inside the box body 11 from the outside of the box body 11, thereby responding in time. One of the embodiments of the present embodiment is that the experimental box 1 adopts a transparent plastic box, which has a lower cost and is convenient to obtain, so that the box body 11 and the box cover 12 are both provided with the above-mentioned transparent part, so that the researcher can clearly observe the experimental mouse from multiple angles, thereby obtaining more comprehensive information.

[0045] Specifically, the side wall of the box body 11 is further provided with a first threading hole 111 and a second threading hole 112, wherein the first threading hole 111 is used for threading the electric acupuncture wire, and the second threading hole 112 is used for threading the part of the belt 2 which is not sleeved with the experimental mouse, so as to fix and arrange the electric acupuncture wire and the belt 2, avoid the random swing of the electric acupuncture wire and the belt 2, and enable the researchers to more conveniently adjust or replace the position of the electric acupuncture wire and the belt 2 through the first threading hole 111 and the second threading hole 112, without the need to frequently open the box cover 12, thereby further reducing unnecessary interference to the experimental mouse, and making the appearance of the auxiliary device more neat and the functionality stronger.

[0046] Specifically, the box cover 12 is provided with a breathable hole (not shown in the figure), which ensures the smooth breathing of the experimental mouse and avoids the hypoxia phenomenon caused by the closed space, thereby being beneficial to maintaining the normal physiological state of the experimental mouse in the long-term intervention experiment.

[0047] Specifically, referring to FIGS. 1, 2 and 3, Figure 2 、 Figure 3 The belt 2 provided by the embodiment includes a first binding part 21, a second binding part 22 and an elastic member 23, and the first binding part 21 and the second binding part 22 are both in a belt structure. One end of the first binding part 21 is connected to one end of the second binding part 22, a waist-shaped sliding hole 211 is arranged at the middle position of the first binding part 21, in the embodiment, the length extension direction of the waist-shaped sliding hole 211 is parallel to the axis direction of the first binding part 21, and an installation groove 212 which is communicated with the waist-shaped sliding hole 211 is arranged inside the other end of the first binding part 21. In one embodiment, the side wall of the installation groove 212 is provided with a communication hole 2121 which is communicated with the waist-shaped sliding hole 211; the other end of the second binding part 22 is bent and inserted into the waist-shaped sliding hole 211, so that the first binding part 21 and the second binding part 22 can jointly enclose the binding ring of the belt 2; the elastic member 23 is arranged in the installation groove 212, one end of the elastic member 23 is fixedly connected to the groove wall of the installation groove 212, and the other end of the elastic member 23 extends into the waist-shaped sliding hole 211 through the communication hole 2121 and is connected to the other end of the second binding part 22.

[0048] Through the above arrangement, when the belt 2 is buckled at the groin of the experimental mouse, the elastic member 23 will be converted from the initial state to the abutting state at this time, and the elastic force is provided to the other end of the second binding part 22 at this time, so that the elastic member 23 can push and drive the other end of the second binding part 22 to slide in the waist-shaped sliding hole 211 towards the end of the first binding part 21, thereby realizing the effect that the experimental mouse can be buckled by the belt 2. In addition, by arranging the elastic member 23 and the waist-shaped sliding hole 211, the size of the loop of the binding ring can be automatically adjusted according to the size of the experimental mouse, so that the tightness is appropriate and human intervention is reduced, which is beneficial to the operation and fixation of the experimental mouse during movement, effectively avoids the condition that the experimental mouse is stimulated by the belt 2 being too tight, or the belt 2 being too loose and the electric acupuncture wire being scattered and damaged by the experimental mouse, and improves the work efficiency and the reliability of the experimental results.

[0049] Preferably, the elastic member 23 is a plastic spring in the embodiment, which has light texture and small volume, and can be well fitted and installed in the installation groove 212. The material of the plastic spring is not limited in the embodiment, which can be PET (polyester), PA (polyamide) or PVC (polyvinyl chloride), etc., as long as the elastic member 23 can realize its function while having good durability, which is within the protection scope of the utility model.

[0050] Further, in the embodiment, the side wall of the waist-shaped sliding hole 211 is provided with a limiting sliding channel 2111 along the axis direction of the first binding part 21, and the other end of the second binding part 22 is provided with a protrusion 221, which is slidably arranged in the limiting sliding channel 2111, so that the other end of the second binding part 22 can be clamped in the waist-shaped sliding hole 211, thereby improving the connection stability of the first binding part 21 and the second binding part 22, and preventing the second binding part 22 from sliding out of the first binding part 21. Preferably, the opposite two side walls of the waist-shaped sliding hole 211 are provided with the limiting sliding channel 2111, and two protrusions 221 are mirror-imaged arranged on the second binding part 22, thereby further improving the connection stability of the second binding part 22 and the first binding part 21.

[0051] Optionally, the auxiliary device further comprises a sensor arranged on the belt 2, and the sensor provided in the embodiment is a pressure sensor, which is used for detecting the binding pressure of the experimental mouse in real time, and will immediately issue an alarm once the pressure is detected to be abnormal, reminding the researchers to timely adjust the belt 2 to prevent the experimental mouse from being subjected to excessive pressure and external stimulation.

[0052] It should be noted that in other parallel embodiments, the sensor can also include at least one of a pressure sensor, a temperature sensor and a heart rate sensor, and can detect at least one of the restraint pressure, the body temperature and the heart rate of the experimental mouse in real time during the experiment, so as to more accurately and comprehensively monitor the physiological activity of the experimental mouse, thereby meeting different experimental requirements. When the pressure, temperature or heart rate is detected to be abnormal, the researcher can manually adjust the belt 2 in time to ensure that the experimental mouse is in a normal physiological state and ensure that the experimental result data is accurate and reliable.

[0053] Optionally, in order to further enhance the comfort of the experimental mouse, a flexible pad is also designed in the embodiment and attached to the inner ring surface of the restraint ring. The flexible pad can be made of flexible polyurethane foam, which not only can provide good cushioning effect to reduce the skin marks of the experimental mouse caused by long-term restraint, but also has certain air permeability to reduce the discomfort of the skin.

[0054] In the description of the present specification, the description referring to the terms "some embodiments", "other embodiments", and the like means that the specific features, structures, materials or characteristics described in connection with the embodiments or examples are included in at least one embodiment or example of the present application. In the present specification, the illustrative description of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0055] Obviously, the above embodiments of the present application are only examples for clearly illustrating the present application, and are not intended to limit the implementation modes of the present application. For those skilled in the art, various obvious changes, readjustments and substitutions can be made without departing from the protection scope of the present application. Here, it is not necessary and impossible to enumerate all the implementation modes. Any modification, equivalent substitution and improvement made within the spirit and principle of the present application shall be included in the protection scope of the claims of the present application.

Claims

1. An auxiliary device suitable for experimental rat head and back acupoint electroacupuncture intervention, characterized in that, The experimental box (1) has an activity chamber (101) for the experimental mouse to walk around; the belt (2) is annular and is sleeved and tightened on the abdomen of the experimental mouse, an electric needle wire is arranged in the restraint ring of the belt (2) and is connected with electric needles inserted into acupoints on the head and back of the experimental mouse, so as to fix the electric needles attached to the back of the experimental mouse through the belt (2).

2. The auxiliary device suitable for electric acupuncture intervention of the head and back acupoints of experimental rats according to claim 1, characterized in that, The belt (2) comprises a first restraint part (21), a second restraint part (22) and an elastic member (23), wherein: One end of the first restraint part (21) is connected to one end of the second restraint part (22), a waist-shaped sliding hole (211) is arranged at the middle position of the first restraint part (21), and an installation groove (212) communicating with the waist-shaped sliding hole (211) is arranged in the other end of the first restraint part (21); The other end of the second restraint part (22) is inserted into the waist-shaped sliding hole (211) after being bent, so that the first restraint part (21) and the second restraint part (22) can jointly form the restraint ring; The elastic member (23) is arranged in the installation groove (212), one end of the elastic member (23) is connected to the groove wall of the installation groove (212), the other end of the elastic member (23) extends into the waist-shaped sliding hole (211) and is connected to the other end of the second restraint part (22), and is used for providing elastic force for the second restraint part (22).

3. The auxiliary device for electric acupuncture intervention on the head and back acupoints of experimental mice according to claim 2, characterized in that, The elastic member (23) is a plastic spring.

4. The auxiliary device for electric acupuncture intervention on the head and back acupoints of experimental rats according to claim 2, characterized in that, A limiting sliding channel (2111) is arranged in the sidewall of the waist-shaped sliding hole (211) along the axis direction of the first restraint part (21), the other end of the second restraint part (22) is provided with a protrusion (221), and the protrusion (221) is slidably arranged in the limiting sliding channel (2111).

5. The auxiliary device for electric acupuncture intervention on the head and back acupoints of experimental rats according to claim 2, characterized in that, The experimental box (1) is provided with a transparent part.

6. The auxiliary device for electric acupuncture intervention on the head and back acupoints of experimental rats according to claim 5, characterized in that, The experimental box (1) comprises a box body (11) and a box cover (12), the box body (11) has the activity chamber (101), the box cover (12) is detachably connected to the box body (11), and the box cover (12) and / or the box body (11) has the transparent part.

7. The auxiliary device for electric acupuncture intervention on the head and back acupoints of experimental rats according to claim 6, characterized in that, The sidewall of the box body (11) has a first wire hole (111) and a second wire hole (112), the first wire hole (111) is used for penetrating the electric needle wire, and the second wire hole (112) is used for penetrating the other end of the second restraint part (22).

8. The auxiliary device for electric acupuncture intervention on the head and back acupoints of experimental rats according to claim 6, characterized in that, The box cover (12) is provided with a breathable hole.

9. The auxiliary device for electric acupuncture intervention in the head and back acupoints of experimental rats according to any one of claims 1-8, characterized in that, The belt (2) is provided with a sensor, the sensor is used for detecting the pressure of the belt (2) on the experimental mouse; And / or, the sensor is used for detecting the body temperature of the experimental mouse; And / or, the sensor is used for detecting the heart rate of the experimental mouse.

10. The auxiliary device for electric acupuncture intervention on the head and back acupoints of experimental rats according to any one of claims 1-8, characterized in that, A plurality of flexible pads are attached to the inner ring surface of the restraint ring.

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