Drug intermediate mixing and heating device

Abstract

The utility model discloses a medicine intermediate mixing and heating device which comprises a tank body, a feed port is formed in a top cover of the tank body, and a discharge port is formed in the lower part of the side wall of the tank body; a stirring mechanism and an anti-precipitation mechanism are arranged in the tank body, and a heating mechanism is arranged on the side wall of the tank body; the stirring mechanism comprises a driving motor arranged at the upper part of the top cover of the tank body and a stirring shaft correspondingly connected with an output shaft of the driving motor, supporting frames are respectively arranged on two sides of the stirring shaft, and a vertical stirring rod and a transverse stirring rod are respectively arranged in the supporting frames on two sides; the anti-precipitation mechanism comprises a ventilation pipeline arranged at the bottom of the tank body, air holes are formed in the ventilation pipeline, and one end of the ventilation pipeline penetrates through the side wall of the tank body and is correspondingly connected with an external air source. According to the utility model, raw materials of drug intermediates can be fully dispersed and uniformly mixed, precipitation is avoided, and the raw materials of the drug intermediates can be more fully mixed and reacted so as to achieve a better reaction effect.

Description

TECHNICAL FIELD

[0001] The utility model relates to medicine intermediate production and processing equipment technical field, concretely relates to a medicine intermediate mixing heating device. BACKGROUND

[0002] Medicine intermediate is some chemical raw material or chemical product used in the medicine synthesis process, is the intermediate product such as raw material, material, auxiliary material used in the production of medicine product, and the production and preparation of many medicines must rely on good medicine intermediate to carry out customization and synthesis. Medicine intermediate is mostly semi-finished product, is the initial product in the process, must be processed by certain process, medicine intermediate is fine chemical product, also needs to pass through a variety of different reaction procedures, such as hydrolysis reaction, substitution reaction, esterification reaction, acylation reaction, etc. in some reaction procedures, different raw materials need to be mixed uniformly and heated, some medicine intermediate raw materials are prone to agglomeration, are not easy to disperse, and are prone to form precipitate at the bottom of mixing heating equipment, are not easy to be mixed uniformly, causing the reaction effect of medicine intermediate to be not ideal. SUMMARY

[0003] The utility model wants to solve the technical problem to provide a medicine intermediate mixing heating device.

[0004] To solve the above-mentioned technical problem, the utility model adopts the following technical scheme:

[0005] Design a kind of medicine intermediate mixing heating device, including tank body, is equipped with feed inlet on tank body top cover, tank body lateral wall lower part is equipped with discharge gate;Stirring mechanism and anti-precipitation mechanism are arranged in the inside of tank body, heating mechanism is equipped on the lateral wall of tank body;

[0006] The stirring mechanism includes the driving motor being arranged in the upper portion of tank body top cover, the stirring shaft being connected with the output shaft of driving motor in correspondence, the stirring shaft extends to the inside of tank body, the support frame is respectively arranged in the two sides of stirring shaft, the vertical stirring rod is arranged in the support frame in one side, the horizontal stirring rod is arranged in the support frame in the other side;

[0007] The anti-precipitation mechanism includes the air pipe being arranged in the bottom of tank body, the air hole is opened in air pipe, one end of air pipe passes through the lateral wall of tank body and is connected with external gas source in correspondence.

[0008] In the above technical scheme, the vertical stirring rod and the horizontal stirring rod are arranged on the two sides of the stirring shaft, so that the material can be fully dispersed during stirring, and the material is more easily mixed uniformly; the anti-settling mechanism is arranged at the bottom of the tank body, gas can be introduced into the air duct, the gas is sprayed out through the air holes, the material at the bottom of the tank body is driven to surge upward, and the material at the bottom of the tank body can be prevented from forming a deposit; and the external gas source can be an air compressor, a blower or the like.

[0009] Preferably, the heating mechanism comprises a main heating belt and a secondary heating belt wound on the side wall of the tank body, the main heating belt and the secondary heating belt are wound on the side wall of the tank body at intervals, and the width of the main heating belt is greater than the width of the secondary heating belt. By arranging the main heating belt and the secondary heating belt, the main heating belt and the secondary heating belt are independently temperature-controlled, the main heating belt and the secondary heating belt can be turned on at the same time to improve the heating speed when initial heating or a higher heating temperature is required, and only the main heating belt or only the secondary heating belt can be turned on to meet the requirements of different heating conditions when it is required to maintain a certain temperature range or slow heating.

[0010] Preferably, the main heating belt and the secondary heating belt are both silicon rubber electric heating belts. The silicon rubber electric heating belt has excellent softness, can be directly wound on the heated device, has good contact, uniform heating, and has the advantages of fast heating, high thermal efficiency and long service life.

[0011] Preferably, a heat preservation shell is arranged outside the heating mechanism, which can play a role in heat preservation of the tank body.

[0012] Preferably, the air duct comprises a main duct and a branch duct, the main duct and the branch duct are connected in communication; the main duct is in communication with the external gas source, and the branch duct forms a passage with the main duct.

[0013] Preferably, the main duct and the branch duct are connected to form a "day" type structure; or the main duct is in the shape of a circular ring, and the branch duct is connected in communication along the diameter of the main duct. The periphery of the air duct can spray gas to the area around the bottom of the tank body, and the middle part of the air duct can spray gas to the area in the middle of the bottom of the tank body, so that the bottom of the tank body can be fully covered by the gas spraying range of the air duct, and the anti-settling effect is better.

[0014] Preferably, the air holes are inclined downward at an angle of 10-45 degrees with the vertical direction. The air holes are inclined downward, so that the sprayed gas is directed toward the bottom of the tank body, which can drive the material deposited at the bottom of the tank body, and prevent the material from accumulating and depositing.

[0015] Preferably, the vertical stirring rod is rotatably connected to the support frame through a rotating shaft at the upper end and the lower end; and the left and right ends of the horizontal stirring rod are rotatably connected to the support frame through rotating shafts.

[0016] Preferably, a drain for flushing is arranged at the bottom of the tank body. After use, water can be injected into the tank body for flushing. During the flushing process, gas can be introduced into the air pipe to spray the bottom of the tank body, so that the tank body is flushed more cleanly. The water after flushing is discharged through the drain at the bottom of the tank body.

[0017] The beneficial effects of the utility model lie in that:

[0018] The utility model discloses a medicine intermediate mixing and heating device, which is characterized in that: a stirring mechanism is arranged, so that the material can be fully dispersed and stirred; a anti-settling mechanism is arranged, so that the tank body bottom can be sprayed to drive the material at the tank body bottom to surge and avoid the material from being accumulated and settled at the tank body bottom; and a heating mechanism is arranged, so that the tank body can be heated and meet different heating conditions. The utility model has the advantages of simple structure and convenient control, can fully disperse and uniformly mix the raw material of the medicine intermediate, avoid settlement, and make the raw material of the medicine intermediate more fully mixed to achieve better reaction effect. BRIEF DESCRIPTION OF DRAWINGS

[0019] Figure 1 It is an internal structure schematic view of the utility model;

[0020] Figure 2 It is a structure schematic view of the heating mechanism;

[0021] Figure 3 It is a structure schematic view of one embodiment of the anti-settling mechanism;

[0022] Figure 4 It is a structure schematic view of another embodiment of the anti-settling mechanism;

[0023] Figure 5 It is a schematic view of the opening mode of the air hole on the air pipe.

[0024] In the drawing, 1 is a tank body, 2 is a feeding port, 3 is a discharging port, 4 is a driving motor, 5 is a stirring shaft, 6 is a support frame, 7 is a vertical stirring rod, 8 is a horizontal stirring rod, 9 is an air pipe, 10 is an air hole, 11 is a main heating belt, 12 is a vice heating belt, 13 is a heat preservation shell, 14 is a main pipe, 15 is a branch pipe, and 16 is a drain. DETAILED DESCRIPTION

[0025] The specific embodiments of the utility model will be described below in combination with the drawings and examples, but the following examples are only used to specifically describe the embodiments of the utility model and do not limit the scope of the utility model in any way.

[0026] Example 1: a medicine intermediate mixing and heating device, as shown in Figures 1-2The device comprises a tank body 1, a feeding port 2 is arranged on the top cover of the tank body 1, a discharging port 3 is arranged on the lower part of the side wall of the tank body 1, and a flushing drain port 16 is arranged on the bottom of the tank body 1; in use, the raw materials of the pharmaceutical intermediates are added into the tank body 1 from the feeding port 2, and after the mixing and heating reaction is completed, the materials are discharged from the discharging port 3 and enter the next processing procedure.

[0027] A stirring mechanism and an anti-settling mechanism are arranged in the tank body 1, and a heating mechanism is arranged on the side wall of the tank body 1; the stirring mechanism is used for stirring the materials in the tank body 1 and making the materials uniformly mixed; the anti-settling mechanism is used for preventing the materials from settling on the bottom of the tank body 1 and affecting the reaction effect; and the heating mechanism is used for heating the tank body 1 and making the materials in the tank body 1 reach the required temperature range for the reaction.

[0028] The stirring mechanism comprises a driving motor 4 arranged on the upper part of the top cover of the tank body 1 and a stirring shaft 5 correspondingly connected with the output shaft of the driving motor 4; the stirring shaft 5 extends into the tank body 1; support frames 6 are arranged on the two sides of the stirring shaft 5; a vertical stirring rod 7 is arranged in one of the support frames 6; and a horizontal stirring rod 8 is arranged in the other support frame 6. The upper and lower ends of the vertical stirring rod 7 are rotatably connected with the support frame 6 through a rotating shaft; and the left and right ends of the horizontal stirring rod 8 are rotatably connected with the support frame 6 through a rotating shaft. The driving motor 4 drives the stirring shaft 5 to rotate, thereby driving the two support frames 6 and the vertical stirring rod 7 and the horizontal stirring rod 8 to rotate, so as to stir the materials; and the arrangement of the vertical stirring rod 7 and the horizontal stirring rod 8 can more fully disperse the materials and make the materials more uniformly dispersed.

[0029] The anti-settling mechanism comprises an air duct 9 arranged on the bottom of the tank body 1, air holes 10 are arranged on the air duct 9, and one end of the air duct 9 penetrates through the side wall of the tank body 1 and is correspondingly connected with an external air source. The air duct 9 comprises a main duct 14 and a branch duct 15, and the main duct 14 and the branch duct 15 are in communication. The air duct 9 is connected with the external air source, so that air is introduced into the air duct 9 and sprayed out from the air holes 10; the air flow can lift the materials on the bottom of the tank body 1, so that the materials on the bottom are upwelled, thereby avoiding the formation of sediment on the bottom. The external air source can be an air compressor or a blower.

[0030] The heating mechanism comprises a main heating belt 11 and a secondary heating belt 12 wound on the side wall of the tank body 1; the main heating belt 11 and the secondary heating belt 12 are wound on the side wall of the tank body 1 at intervals, and the width of the main heating belt 11 is greater than that of the secondary heating belt 12. In this embodiment, the main heating belt 11 and the secondary heating belt 12 are both silicon rubber electric heating belts. A heat preservation shell 13 is arranged on the outside of the heating mechanism. The main heating belt 11 and the secondary heating belt 12 can be independently switched on or off, simultaneously switched on or only one of them is switched on, so as to meet different heating requirements.

[0031] Embodiment 2: a medicine intermediate mixing and heating device, further to embodiment 1, the air hole 10 is inclined towards the bottom, the included angle a between the air hole 10 and the vertical direction is 10-45 degrees, see Figure 5 The air hole 10 is inclined towards the bottom at a certain angle, so that the air flow spraying direction is towards the bottom of the tank, and the air flow can impact the material deposited at the bottom, so that the anti-deposition effect is better.

[0032] Embodiment 3: a medicine intermediate mixing and heating device, further to embodiment 2, the main pipeline 14 and the branch pipeline 15 are connected to form a "day" type structure, see Figure 3 .

[0033] Embodiment 4: a medicine intermediate mixing and heating device, different from embodiment 3, the main pipeline 14 is a circular ring shape, and the branch pipeline 15 is connected along the diameter of the main pipeline 14, see Figure 4 .

[0034] In the above embodiments, the device elements are conventional device elements unless otherwise specified.

[0035] The specific working mode of the medicine intermediate mixing and heating device is as follows: the raw materials of the medicine intermediate are added into the tank from the feeding port, the heating mechanism is started, the tank is heated according to the temperature requirement, the driving motor is started, the stirring shaft is driven to rotate, the vertical stirring rod and the horizontal stirring rod on both sides are driven to rotate, the material in the tank is stirred and dispersed, the external gas source can intermittently introduce gas into the ventilation pipeline, a gas flow is formed at the bottom of the tank, the material at the bottom of the tank is driven to surge upwards, so that the material is prevented from being deposited. After the mixing reaction is completed, the material is discharged from the lower discharge port and enters the next processing procedure. When the tank needs to be cleaned, water is injected into the tank, and the stirring mechanism is started, so that the water in the tank cleans the inner wall of the tank, or the external gas source is started, the air flow sprayed from the air hole can flush the residual material at the bottom of the tank, and the flushed water is discharged from the drain hole at the bottom of the tank.

[0036] The embodiments of the utility model are described in detail above in combination with the drawings and the embodiments, but the utility model is not limited to the above-mentioned embodiments, and within the knowledge range of the ordinary skilled in the art, the utility model can also be changed or changed without departing from the purpose of the utility model.

Claims

1. A pharmaceutical intermediate mixed heating device, comprising a tank body, a feeding port is arranged on the top cover of the tank body, and a discharging port is arranged at the lower part of the side wall of the tank body; characterized in that, A stirring mechanism and a sediment prevention mechanism are provided inside the tank body, and a heating mechanism is provided on the side wall of the tank body; The stirring mechanism includes a driving motor arranged on the upper part of the tank body top cover, a stirring shaft correspondingly connected to the output shaft of the driving motor, the stirring shaft extends into the tank body, support frames are respectively arranged on both sides of the stirring shaft, a vertical stirring rod is arranged in the support frame on one side, and a horizontal stirring rod is arranged in the support frame on the other side; The sediment prevention mechanism includes an air vent pipe arranged at the bottom of the tank body, air holes are formed in the air vent pipe, and one end of the air vent pipe passes through the side wall of the tank body and is correspondingly connected to an external air source.

2. The pharmaceutical intermediate hybrid heating apparatus of claim 1, wherein, The heating mechanism includes a main heating belt and a sub-heating belt wound around the side wall of the tank body, the main heating belt and the sub-heating belt are wound around the side wall of the tank body at intervals, and the width of the main heating belt is greater than the width of the sub-heating belt.

3. The pharmaceutical intermediate hybrid heating apparatus of claim 2, wherein, Both the main heating belt and the sub-heating belt are silicone rubber electric heating belts.

4. The pharmaceutical intermediate hybrid heating apparatus of claim 2, wherein, A heat preservation housing is arranged outside the heating mechanism.

5. The pharmaceutical intermediate hybrid heating apparatus of claim 1, wherein, The air vent pipe includes a main pipe and a branch pipe, and the main pipe and the branch pipe are communicated with each other.

6. The pharmaceutical intermediate hybrid heating apparatus of claim 5, wherein, The main pipe and the branch pipe are connected to form a "day" - shaped structure; or the main pipe is circular in shape, and a branch pipe is communicated along its diameter inside the main pipe.

7. The pharmaceutical intermediate hybrid heating apparatus of claim 1, wherein, The air holes are arranged to incline downward, and the included angle with the vertical direction is 10 - 45 degrees.

8. The pharmaceutical intermediate hybrid heating apparatus of claim 1, wherein, The upper and lower ends of the vertical stirring rod are rotationally connected to the support frame through a rotating shaft; the left and right ends of the horizontal stirring rod are rotationally connected to the support frame through a rotating shaft.

9. The pharmaceutical intermediate hybrid heating apparatus of claim 1, wherein, A drain port for flushing is provided at the bottom of the tank body.

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