Mouse Morse maze box
By designing a mouse Morse maze box with charged and uncharged areas, and using voltage stimulation to guide mice to search in the uncharged area, the problems of water choking and stimulation effects in water mazes were solved, and accurate memory function testing was achieved.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-25
- Publication Date
- 2026-03-06
AI Technical Summary
In existing technologies, mice are prone to choking on water during water maze experiments. The stimulation of water affects short-term memory, leading to biased test results.
A mouse Morse maze box was designed, which uses a box structure with charged and uncharged areas. The mouse searches in the uncharged area by stimulating it with voltage. The memory function of the mouse is recorded by the regional differences formed by the metal plate and the insulating plate, combined with the adjustable voltage and movable reference objects.
This avoids the risk of mice choking on water, reduces stimulation to mice, and ensures the accuracy and reliability of test results.
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Figure CN223969115U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of animal experimental device technology, specifically to a mouse Morse maze box. Background Technology
[0002] Mazes are primarily used to test the learning and memory abilities of laboratory animals in terms of spatial location and orientation (spatial orientation). They are widely used in scientific research and computer-aided teaching in many disciplines, including learning and memory, Alzheimer's disease, hippocampal research, intelligence and aging, new drug development / screening / evaluation, pharmacology, preventive medicine, neurobiology, animal psychology, and behavioral biology. They have gained widespread recognition worldwide and are the preferred classic experiment for universities to conduct behavioral research, especially research on learning and memory.
[0003] Patent CN203912910U discloses a water maze, including a cylindrical body and a platform disposed inside the cylindrical body. A column is disposed at the center of the bottom surface of the cylindrical body, and an animal placement device is sleeved on the column. The animal placement device includes a hollow cylinder with a bottom bottom and through holes on the bottom bottom. A top cover is disposed on the top surface of the cylinder. A first sleeve is disposed at the center of the bottom surface of the top cover, and a second sleeve is disposed at the center of the top surface of the bottom bottom.
[0004] When using the aforementioned existing technology, mice need to search for targets hidden underwater. However, mice are prone to choking on water, and the stimulation of water may also affect their short-term memory, thus causing deviations in the test results. Utility Model Content
[0005] The purpose of this invention is to overcome the above-mentioned technical deficiencies and propose a mouse Morse maze box to solve the technical problems in the prior art where mice are prone to choking on water, and the stimulation of water on mice may also affect their short-term memory, thus causing deviations in test results.
[0006] To achieve the above-mentioned technical objectives, the present invention adopts the following technical solution:
[0007] This invention provides a mouse Morse maze box, comprising:
[0008] A housing, wherein the housing has a cavity, the bottom of the cavity being divided into a charged area and a non-charged area, the charged area being larger than the non-charged area; and
[0009] A reference object is disposed on the side wall of the cavity.
[0010] In some embodiments, the mouse Morse maze box further includes a metal plate and an insulating plate. The metal plate is adapted to the cavity and is disposed at the bottom of the cavity. The metal plate is energized and has mounting holes. The metal plate constitutes the energized area. The insulating plate is mounted in the mounting holes. The upper surface of the insulating plate is on the same plane as the upper surface of the metal plate. The insulating plate constitutes the de-energized area.
[0011] In some embodiments, the cavity is cylindrical, and the center of the mounting hole is spaced apart from the center of the metal plate.
[0012] In some embodiments, the mouse Morse maze box further includes a power supply device located on the outside of the box body and electrically connected to the metal plate. The voltage of the power supply device is adjustable.
[0013] In some embodiments, the mouse Morse maze box further includes a pressure sensor located at the bottom of the metal plate, the pressure sensor being used to detect pressure changes at various points on the metal plate.
[0014] In some embodiments, the reference object is movably configured such that its position relative to the non-electric region is adjustable.
[0015] In some embodiments, the sidewalls of the cavity are provided with magnetic elements arranged in a complete circle;
[0016] One end of the reference object is provided with an adsorption element, which magnetically engages with the magnetic element.
[0017] In some embodiments, the cavity sidewall is provided with a plurality of mounting portions, and the plurality of mounting portions are evenly spaced along the circumference of the cavity;
[0018] The reference object is provided with a mating part that cooperates with the mounting part. The reference object can be installed with different mounting parts so that the position of the reference object relative to the non-electric area is adjustable.
[0019] In some embodiments, the mounting portion includes an insertion hole provided on the side wall of the cavity;
[0020] The mating part includes a plug located at one end of the reference object.
[0021] In some embodiments, the upper end of the cavity is open;
[0022] The mouse Morse maze box also includes a camera, which is located above the box and faces the cavity.
[0023] Compared with existing technologies, the mouse Morse maze box provided by this invention has a charged area that is much larger than the uncharged area. Furthermore, the voltage in the charged area is low and only stimulates the mouse without causing harm. The reference object is used to refer to the uncharged area, helping the mouse remember it. In practical use, the mouse is placed in the cavity, and it is stimulated in the charged area, forcing it to continuously explore the uncharged area. The time and route taken by the mouse to find the uncharged area are recorded, thereby achieving the purpose of testing the mouse's memory function. This application has a simple structure, is easy to operate, and uses a gentle voltage that causes minimal stimulation to the mouse, thus avoiding deviations in the test results.
[0024] The above description is merely an overview of the technical solution of this utility model. To better understand the technical means of this utility model and to enable its implementation according to the description, the preferred embodiments of this utility model are described in detail below with reference to the accompanying drawings. Specific implementation methods of this utility model are given in detail in the following embodiments and their accompanying drawings. Attached Figure Description
[0025] Figure 1 This is a schematic diagram of the structure of an embodiment of the mouse Morse maze box provided by this utility model;
[0026] Figure 2 yes Figure 1 Top view of the Morse maze box for medullomy mice;
[0027] Figure 3 yes Figure 1 Cross-sectional view of a Morse maze box for medullomyeloid mice;
[0028] Figure 4 This is a cross-sectional view of an embodiment of the mouse Morse maze box provided by this utility model.
[0029] Explanation of reference numerals in the attached figures:
[0030] 1-Box body, 2-Reference object, 3-Metal plate, 4-Insulating plate, 5-Power supply device, 6-Magnetic component, 7-Adsorption component, 8-Pressure sensor, 9-Camera. Detailed Implementation
[0031] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model.
[0032] To address the technical problems in existing technologies where mice are prone to choking on water, and where water stimulation may affect their short-term memory, leading to biased test results, this invention provides a mouse Morse maze box that can avoid such biased test results.
[0033] Please see Figure 1 , Figure 1 This is a schematic diagram of the structure of a mouse Morse maze box in one embodiment of the present invention.
[0034] This utility model provides a mouse Morse maze box, including a box body 1 and a reference object 2. The box body 1 has a cavity, and the bottom of the cavity is divided into an electrified area and a non-electrified area, with the electrified area being larger than the non-electrified area. The reference object 2 is disposed on the side wall of the cavity.
[0035] In this embodiment, please refer to Figures 1 to 3 The charged region is much larger than the uncharged region, and the voltage in the charged region is small, only stimulating the mouse without causing harm. The reference object 2 is used to refer to the uncharged region, helping the mouse remember the uncharged region. In specific use, the mouse is placed in the cavity, and the mouse will be stimulated in the charged region, thus forcing it to continuously explore the uncharged region. The time and route taken by the mouse to find the uncharged region are recorded, thereby achieving the purpose of testing the mouse's memory function. This application has a simple structure, is easy to operate, and has a gentle voltage that causes little stimulation to the mouse, thus avoiding deviations in the test results.
[0036] In one embodiment, please refer to Figures 1 to 3 The mouse Morse maze box also includes a metal plate 3 and an insulating plate 4. The metal plate 3 is adapted to the cavity and is located at the bottom of the cavity. The metal plate 3 is energized and has mounting holes. The metal plate 3 constitutes the energized area. The insulating plate 4 is installed in the mounting holes. The upper side of the insulating plate 4 is on the same plane as the upper side of the metal plate 3. The insulating plate 4 constitutes the de-energized area.
[0037] In this embodiment, the housing 1 is made of insulating material, and the size of the metal plate 3 is adapted to the size of the cavity, so that the metal plate 3 can be seamlessly attached to the bottom of the cavity. The metal plate 3 can be charged, thereby forming the charged area for stimulating mice. The thickness of the insulating plate 4 is the same as the thickness of the metal plate 3, and the size of the insulating plate 4 is the same as the size of the mounting hole, so that the insulating plate 4 can be seamlessly installed in the mounting hole, ensuring that there is no obvious difference between the surfaces of the insulating plate 4 and the metal plate 3. The insulating plate 4 constitutes the non-charged area.
[0038] In one embodiment, please refer to Figures 1 to 3 The cavity is cylindrical, and the center of the mounting hole is spaced apart from the center of the metal plate 3.
[0039] In this embodiment, the housing 1 is cylindrical in shape, the cavity is cylindrical, the metal plate 3 is circular, the mounting hole is circular, the insulating plate 4 is circular, and the mounting hole is eccentric.
[0040] In one embodiment, please refer to Figure 1 The mouse Morse maze box also includes a power supply device 5, which is located on the outside of the box body 1 and is electrically connected to the metal plate 3. The voltage of the power supply device 5 is adjustable.
[0041] In this embodiment, the power supply device 5 is located on the outside of the box 1. The power supply device 5 is connected to the metal plate 3 through a wire, thereby making the metal plate 3 energized. The voltage of the power supply device 5 can be adjusted to adjust the voltage of the metal plate 3 according to the size of the mouse, so as to avoid harming the mouse due to excessive voltage.
[0042] In one embodiment, please refer to Figure 3 The mouse Morse maze box also includes a pressure sensor 8, which is located at the bottom of the metal plate 3 and is used to detect pressure changes at various points on the metal plate 3.
[0043] In this embodiment, in order to facilitate the recording of the mouse's movement route, a pressure sensor 8 is also provided at the bottom of the metal plate 3. The pressure sensor 8 can detect the pressure changes at various points on the metal plate 3, thereby recording the mouse's movement route based on the pressure changes at various points on the metal plate 3.
[0044] In one embodiment, please refer to Figures 1 to 3 The reference object 2 is movably set so that its position relative to the non-electric region is adjustable.
[0045] In this embodiment, in order to investigate the effect of reference object 2 at different positions on mice, reference object 2 is movably installed on the side wall of the cavity, so that the position of reference object 2 relative to the insulating plate 4 can be changed, thereby achieving the experimental purpose by moving the position of reference object 2.
[0046] In one embodiment, please refer to Figures 1 to 3 The cavity has a magnetic element 6 arranged in a complete circle on its side wall; one end of the reference object 2 has an adsorption element 7, which magnetically attracts the magnetic element 6.
[0047] In this embodiment, the sidewall of the cavity is mounted on a magnetic component 6 arranged in a ring, and one end of the reference object 2 is mounted on the adsorption component 7. The magnetic cooperation between the adsorption component 7 and the magnetic component 6 achieves the purpose of fixing the reference object 2. Since the magnetic component 6 is arranged in a complete ring, the reference object can be fixed at any position.
[0048] In another embodiment, the cavity sidewall is provided with a plurality of mounting portions, which are evenly spaced along the circumference of the cavity; the reference object 2 is provided with a mating portion that cooperates with the mounting portions, and the reference object 2 can be installed with different mounting portions so that the position of the reference object 2 relative to the non-electric area is adjustable.
[0049] Specifically, the mounting part includes an insertion hole provided on the side wall of the cavity; the mating part includes a plug provided at one end of the reference object 2.
[0050] In another embodiment, please refer to Figure 4 The cavity has an open upper end; the mouse Morse maze box also includes a camera 9, which is located above the box body 1 and faces the cavity. The camera 9 can also record the mouse's movement trajectory.
[0051] To better understand this utility model, the following is combined with... Figures 1 to 4 The technical solution of this utility model is described in detail below:
[0052] In practical use, a mouse is placed in the cavity. The mouse will be stimulated in the charged area, which will force it to continuously explore the uncharged area. The time and route taken by the mouse to find the uncharged area are recorded, thereby achieving the purpose of detecting the mouse's memory function. This application has a simple structure and is easy to operate. The voltage is gentle and causes less stimulation to the mouse, thus avoiding deviations in the test results.
[0053] The specific embodiments of this utility model described above do not constitute a limitation on the scope of protection of this utility model. Any other corresponding changes and modifications made based on the technical concept of this utility model should be included within the scope of protection of the claims of this utility model.
Claims
1. A mouse Morris maze box, characterized by, It comprises: a box body provided with a cavity, the cavity bottom is provided with a charged area and an uncharged area, the charged area is larger than the uncharged area; and a reference object provided on the side wall of the cavity.
2. The mouse Morris maze box according to claim 1, characterized in that, The mouse morris maze box further comprises a metal plate and an insulating plate, the metal plate is matched with the cavity, the metal plate is provided on the cavity bottom, the metal plate is provided with a charged setting, the metal plate is provided with a mounting hole, the metal plate constitutes the charged area, the insulating plate is mounted on the mounting hole, the upper side of the insulating plate is in the same plane with the upper side of the metal plate, and the insulating plate constitutes the uncharged area.
3. The mouse Morris maze box according to claim 2, wherein, The cavity is provided in a cylindrical shape, and the center of the mounting hole is spaced apart from the center of the metal plate.
4. The mouse Morris maze box according to claim 2, wherein, The mouse morris maze box further comprises a power supply device, the power supply device is provided outside the box body, the power supply device is electrically connected with the metal plate, and the voltage of the power supply device is adjustably set.
5. The mouse Morris maze box according to claim 2, wherein, The mouse morris maze box further comprises a pressure sensor, the pressure sensor is provided on the bottom of the metal plate, and the pressure sensor is used for detecting the pressure change of each part of the metal plate.
6. The mouse Morris maze box according to claim 1, wherein, The reference object is movably provided, so that the position of the reference object relative to the uncharged area is adjustable.
7. The mouse Morris maze box according to claim 6, wherein, The side wall of the cavity is provided with a magnetic member arranged in a whole circle; One end of the reference object is provided with a suction accessory, and the suction accessory is magnetically attracted to the magnetic member.
8. The mouse Morris maze box according to claim 6, wherein, The side wall of the cavity is provided with a plurality of mounting portions, and the plurality of mounting portions are uniformly and spaced apart along the circumference of the cavity; The reference object is provided with a matching portion matched with the mounting portion, and the reference object can be installed in different mounting portions, so that the position of the reference object relative to the uncharged area is adjustable.
9. The mouse Morris maze box according to claim 8, characterized in that, The mounting portion comprises a jack provided on the side wall of the cavity; The matching portion comprises a plug provided on one end of the reference object.
10. The mouse Morris maze box according to claim 1, wherein, The upper end of the cavity is provided with an opening; The mouse morris maze box further comprises a camera, the camera is provided above the box body and faces the cavity.
Citation Information
Patent Citations
Water maze
CN203912910U