Sample mixing device for pharmaceutical quality detection

By designing a mixing device with a movable placement platform and a height-adjustable shaking circular plate, the problem that existing devices can only mix one group at a time was solved, enabling simultaneous mixing of tablet powder and solution in multiple test tubes, thus improving mixing efficiency.

CN224051748UActive Publication Date: 2026-03-27TIANJIN BIOCHEM PHARMA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-04-18
Publication Date
2026-03-27

AI Technical Summary

Technical Problem

Existing sample mixing devices can only mix one set of samples and solutions at a time, which cannot meet the need for mixing multiple sets of samples simultaneously, resulting in inconvenience in use.

Method used

A mixing device was designed, which includes a movable placement platform and a liftable shaking disc. Multiple test tubes are clamped, fixed, and shaken by a drive component and a shaking component to ensure thorough mixing of the tablet powder and the solution.

Benefits of technology

This technology enables simultaneous mixing of drug powder and solution in multiple test tubes, improving mixing efficiency and facilitating pharmaceutical quality testing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of sample mixing devices, and discloses a sample mixing device for pharmaceutical quality detection, which comprises a mixing box internally provided with a cavity, a movable placing table arranged in the cavity, a plurality of placing grooves arranged on the placing table along the circumferential direction and used for placing test tubes, and clamping plates arranged in the placing grooves, a cavity is further formed in the center position in the containing table, and a driving assembly is arranged in the cavity. A liftable shaking circular plate is arranged in the cavity, and a shaking assembly is further arranged in the cavity. By means of the structure, the multiple clamping plates are driven by the driving assembly to clamp and fix test tubes in the corresponding containing grooves, so that the multiple test tubes can be fixed to the containing table, and when the shaking assembly drives the containing table to shake through the shaking circular plate, the test tubes located in the containing grooves can shake; therefore, the tablet powder and the solution in the multiple groups of test tubes are mixed, so that the use is convenient.
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Description

TECHNICAL FIELD

[0001] The utility model relates to sample mixing device technical field, specifically, relate to a sample mixing device for pharmaceutical quality detection. BACKGROUND

[0002] In the pharmaceutical process, the tablets are sampled, and then the tablets are detected to ensure the quality and safety of the medicine; when the components of the tablets are detected, the tablets are crushed into powder, at this time, the tablet powder is added to the solution (such as water), and the solution and the tablet powder are mixed by the mixing device, so that the tablet powder can be uniformly distributed in the solution, and finally the mixed solution is detected by the detection equipment, so that the detection of the tablets can be realized.

[0003] For example, the patent with the publication number CN218422509U discloses a mixing device for sample detection, which can separate the stirring shaft and the sealing cover from the sleeve through the fixing mechanism arranged on the mixing mechanism, so as to facilitate the cleaning of the mixing mechanism, the disassembly and assembly process is simple and fast, the mixing mechanism is not polluted by the pharmaceutical detection sample, and the detection result is not affected; however, the mixing device for sample detection can only mix one group of samples and solution at a time, and when multiple groups of samples and solution need to be mixed, the mixing needs to be carried out in sequence, which is inconvenient to use, and needs to be improved. SUMMARY

[0004] The utility model aims at providing a sample mixing device for pharmaceutical quality detection to solve the problems in the background art.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical scheme:

[0006] A sample mixing device for pharmaceutical quality detection, comprising a mixing box with a cavity, the cavity is provided with a movable placement table, a plurality of placement grooves for placing test tubes are formed on the placement table in the circumferential direction, a clamping plate is arranged in each placement groove, a cavity is further arranged at the center position of the placement table, a driving assembly is arranged in the cavity, and the driving assembly is used for driving the plurality of clamping plates to clamp and fix the test tubes in the placement grooves.

[0007] A lifting and shaking round plate is arranged in the cavity, a shaking assembly is further arranged in the cavity, the shaking assembly is used for driving the lifting and shaking round plate to shake, and the driving assembly is further used for connecting the placement table and the lifting and shaking round plate, so that the lifting and shaking round plate drives the placement table to shake.

[0008] Preferably, the clamping plates are each provided with a moving rod extending into the cavity, the moving rods in the cavity are each provided with a moving block, and the moving blocks are each provided with a first inclined surface;

[0009] The driving assembly comprises a threaded rod arranged in the cavity and threaded through the placement table at both ends, a pressing block is sleeved on the threaded rod in the cavity, a second inclined surface matched with the plurality of first inclined surfaces is formed in the side wall of the pressing block, and the threaded rod is rotated to drive the pressing block to press the moving blocks, so that the clamping plates clamp and fix the test tubes in the placement grooves.

[0010] Preferably, a plurality of support plates are arranged on the bottom wall of the cavity along the circumference thereof and allow the corresponding moving rods to penetrate, springs are sleeved on the moving rods located on the support plates and the pressing block, and the springs are used to push the pressing block away from the support plates.

[0011] Preferably, a threaded cylinder is arranged on the upper end surface of the shaking disc, and a threaded groove with an upward opening and allowing the lower end of the threaded rod to be threaded is formed in the threaded cylinder.

[0012] Preferably, limit grooves are formed in the opposite side walls of the cavity, limit plates are arranged on the side wall of the shaking disc in opposition and are clamped into the corresponding limit grooves at one end, a plurality of shaking blocks are arranged on the lower end surface of the shaking disc along the circumference thereof, the shaking blocks are each provided with a matched inclined surface, and a partition plate is further arranged below the shaking disc.

[0013] The shaking assembly comprises a driving disc arranged on the partition plate and being rotatable, a plurality of driving blocks are arranged on the upper end surface of the driving disc along the circumference thereof, the driving blocks are each provided with a pressing inclined surface matched with the matched inclined surface, and the driving disc is rotated to drive the driving blocks to press the shaking blocks, so that the shaking disc drives the placement table to shake.

[0014] Preferably, fixed grooves are formed in the opposite side walls of the cavity, and fixed blocks are arranged on the side wall of the placement table in opposition and are clamped into the corresponding fixed grooves.

[0015] Preferably, a rotating handle for driving the threaded rod to rotate is arranged at the upper end of the threaded rod.

[0016] Compared with the prior art, the utility model has the advantages that:

[0017] 1. The utility model discloses a sample mixing device for pharmaceutical quality detection, which comprises a cavity, a plurality of clamping plates arranged in the cavity, a plurality of placement grooves arranged on the clamping plates, a plurality of test tubes arranged in the placement grooves, a shaking disc arranged below the placement table, a shaking assembly arranged on the shaking disc, and a driving assembly arranged on the cavity.

[0018] The utility model discloses, clamping plate is towards the side wall fixed mounting of test tube has rubber pad, when driving assembly drives clamping plate to carry out clamping fixed to the test tube in the placing groove, clamping plate can carry out clamping fixed to the test tube through rubber pad to make clamping plate to the clamping fixed effect of test tube better. BRIEF DESCRIPTION OF DRAWINGS

[0019] Figure 1 It is the structure schematic drawing of sample mixing device for pharmaceutical quality detection in the utility model.

[0020] Figure 2 It is the sectional structure schematic drawing of placing table installation in mixing box in the utility model.

[0021] Figure 3 It is the structure schematic drawing in cavity in the utility model.

[0022] Figure 4 It is the structure schematic drawing of thread block and extrusion block in the utility model.

[0023] Figure 5 It is the structure schematic drawing of wobble round plate and drive round plate in the utility model.

[0024] The meaning of each reference numeral in the drawing is as follows:

[0025] 100, mixing box;110, placing table;111, fixed block;120, turn hand;

[0026] 201, cavity;202, limit slot;203, fixed slot;211, placing groove;212, cavity;220, clamping plate;230, wobble round plate;231, thread cylinder;232, limit plate;233, wobble block;234, intercept plate;240, moving rod;241, moving block;250, thread rod;251, extrusion block;252, second inclined plane;260, support plate;270, spring;280, partition;290, drive round plate;291, drive block;292, motor;

[0027] 300, first inclined plane;

[0028] 501, matching inclined plane;511, extrusion inclined plane. DETAILED DESCRIPTION

[0029] For further understanding the contents of the utility model, the utility model is described in detail in the combination of drawings and examples. It should be understood that the example is only explained the utility model and is not limited.

[0030] The following is combined with the drawings Figures 1-5 The example is further described in detail.

[0031] For example Figure 1As shown, the sample mixing device for pharmaceutical quality detection in the embodiment comprises a mixing box 100 provided with a cavity 201, the cavity 201 is provided with a movable placement table 110, a plurality of placement grooves 211 for placing test tubes are formed on the placement table 110 in a circumferential direction, the placement grooves 211 are each provided with a clamping plate 220, and a cavity 212 is further arranged at a central position in the placement table 110, the cavity 212 is provided with a driving assembly, and the driving assembly is used to drive the plurality of clamping plates 220 to clamp and fix the test tubes in the placement grooves 211.

[0032] The cavity 201 is provided with a liftable shaking disc 230, and the cavity 201 is further provided with a shaking assembly, the shaking assembly is used to drive the shaking disc 230 to shake, and the driving assembly is further used to connect the placement table 110 and the shaking disc 230, so that the shaking disc 230 drives the placement table 110 to shake.

[0033] In the embodiment, the sample tablets need to be crushed into powder in advance, then the tablet powder is added into the test tube containing the solution, and then the opening of the test tube is sealed by the plug. At this time, the test tube containing the solution and the tablet powder is placed in the corresponding placement groove 211, and the clamping plate 220 is driven by the driving assembly to clamp and fix the test tube in the placement groove 211, so as to fix the test tube in the placement groove 211. At the same time, the driving assembly also connects the placement table 110 to the shaking disc 230. When the tablet powder and the solution in the test tube need to be mixed, the shaking disc 230 is driven by the shaking assembly to shake continuously, and the shaking disc 230 drives the placement table 110 to shake, so that the test tube in the placement groove 211 is shaken, so that the tablet powder in the test tube can be fully mixed with the solution.

[0034] When a plurality of test tubes need to be mixed, the plurality of test tubes are sequentially placed in the corresponding placement grooves 211, and then the clamping plates 220 are driven by the driving assembly to clamp and fix the test tubes in the corresponding placement grooves 211, so that the plurality of test tubes can be fixed on the placement table 110. When the placement table 110 is driven by the shaking disc 230 to shake, the test tubes in the placement grooves 211 can be shaken, so as to mix the tablet powder and the solution in the plurality of test tubes. Compared with the prior art, the sample mixing device for pharmaceutical quality detection can mix the tablet powder and the solution in a plurality of test tubes at a time during actual use, thereby facilitating use.

[0035] The clamping plate 220 is fixedly installed with a rubber pad towards the side wall of the test tube. When the clamping plate 220 is driven by the driving assembly to clamp and fix the test tube in the placement groove 211, the clamping plate 220 can clamp and fix the test tube through the rubber pad, so that the clamping and fixing effect of the clamping plate 220 on the test tube is better.

[0036] In actual use, the clamping plate 220 and the rubber pad are both in the shape of a circular arc. When the clamping plate 220 clamps and fixes the test tube through the rubber pad, the side wall of the rubber pad can better fit the side wall of the test tube, so that the clamping effect of the clamping plate 220 on the test tube is better.

[0037] As Figures 1-4 In the embodiment, the clamping plate 220 is provided with a moving rod 240 extending into the cavity 212 at one end, the moving rod 240 in the cavity 212 is provided with a moving block 241, and the moving block 241 is provided with a first inclined surface 300.

[0038] The driving assembly comprises a threaded rod 250 arranged in the cavity 212 and threaded through the placement table 110 at both ends, a pressing block 251 arranged in the cavity 212 and sleeved on the threaded rod 250, a second inclined surface 252 arranged on the side wall of the pressing block 251 and matched with the plurality of first inclined surfaces 300, and the threaded rod 250 drives the pressing block 251 to press the moving block 241 to realize clamping and fixing of the test tube in the placement groove 211 by the clamping plate 220.

[0039] In the embodiment, the moving rod 240, the moving block 241, the first inclined surface 300, the threaded rod 250, the pressing block 251 and the second inclined surface 252 are arranged, so that one end of the moving rod 240 is fixedly installed on the clamping plate 220, the moving block 241 is fixedly installed at the other end of the moving rod 240, and the pressing block 251 is fixedly installed on the threaded rod 250. When the threaded rod 250 rotates, the threaded rod 250 drives the pressing block 251 to ascend and descend in the cavity 212. When the threaded rod 250 drives the pressing block 251 to descend, the second inclined surface 252 on the pressing block 251 presses the first inclined surface 300 on the moving block 241, so that the moving block 241 can drive the clamping plate 220 to move towards the test tube through the moving rod 240, thereby realizing clamping and fixing of the test tube in the placement groove 211 by the clamping plate 220.

[0040] The bottom wall of the cavity 212 is fixedly installed with a plurality of support plates 260 around the circumference, and the moving rods 240 are arranged through the support plates 260. The moving rods 240 arranged on the support plates 260 and the pressing block 251 are both sleeved with springs 270, and the springs 270 are used to push the pressing block 251 away from the support plates 260. When the threaded rod 250 drives the pressing block 251 to ascend, the second inclined surface 252 on the pressing block 251 releases the pressing on the first inclined surface 300. At this time, the clamping plate 220 releases the clamping and fixing of the test tube, and at the same time, the spring 270 starts to push the moving block 241 to move. The moving block 241 can drive the clamping plate 220 to move away from the test tube through the moving rod 240, so as to put the subsequent test tube into the placement groove 211.

[0041] The upper end surface of the shaking circular plate 230 is fixed with a threaded cylinder 231, and the threaded cylinder 231 is provided with a threaded groove with an upward opening for the lower end of the threaded rod 250 to be screwed into. When the placing table 110 is located in the cavity 201, the rotation of the threaded rod 250 will drive the clamping plate 220 to move towards the test tube. At the same time, the lower end of the threaded rod 250 is screwed into the threaded groove, so that the threaded rod 250 is connected with the shaking circular plate 230, that is, the placing table 110 is installed in the mixing box 100, so that the shaking of the shaking circular plate 230 can drive the threaded rod 250 to shake, that is, the placing table 110 is shaken.

[0042] When the threaded rod 250 is lowered and the lower end of the threaded rod 250 is screwed into the upper end of the threaded groove, the pressing block 251 on the threaded rod 250 drives the clamping plate 220 to move through the moving block 241. At this time, the clamping plate 220 does not clamp and fix the test tube in the placing groove 211. When the threaded rod 250 is lowered and the lower end of the threaded rod 250 is screwed into the middle end of the threaded groove, the pressing block 251 on the threaded rod 250 can drive the clamping plate 220 to clamp and fix the test tube in the placing groove 211. In actual use, only the lower end of the threaded rod 250 needs to be raised to the upper end of the threaded groove, and the test tube can be taken out of the placing groove 211.

[0043] In actual use, the upper end of the threaded rod 250 is fixedly installed with a rotating handle 120 for driving the threaded rod 250 to rotate. The worker can conveniently drive the threaded rod 250 to rotate through the rotating handle 120.

[0044] As shown in Figures 1-5 In this embodiment, the opposite side walls of the cavity 201 are provided with limiting grooves 202, the side wall of the shaking circular plate 230 is provided with opposite limiting plates 232 which are clamped into the corresponding limiting grooves 202 at one end, the lower end surface of the shaking circular plate 230 is provided with a plurality of shaking blocks 233 along the circumference thereof, and the lower side of the shaking circular plate 230 is further provided with a partition plate 280.

[0045] The shaking assembly comprises a driving circular plate 290 which is rotatable and arranged on the partition plate 280. The upper end surface of the driving circular plate 290 is provided with a plurality of driving blocks 291 along the circumference thereof. The driving blocks 291 are each provided with a pressing inclined surface 511 which cooperates with the matching inclined surface 501. The driving circular plate 290 is rotated to drive the driving blocks 291 to press the shaking blocks 233, so that the shaking circular plate 230 drives the placing table 110 to shake.

[0046] In the embodiment, through the setting of the limiting groove 202, the limiting plate 232, the shaking block 233, the matching inclined surface 501, the partition plate 280, the driving circular plate 290, the driving block 291 and the extrusion inclined surface 511, the limiting plate 232 is fixedly installed on the shaking circular plate 230, the shaking block 233 is fixedly installed on the shaking circular plate 230, the partition plate 280 is fixedly installed on the side wall of the cavity 201, and the driving block 291 is fixedly installed on the driving circular plate 290. When the driving circular plate 290 continuously rotates on the partition plate 280, the driving circular plate 290 can extrude the matching inclined surface 501 on the shaking block 233 through the extrusion inclined surface 511 on the driving block 291, so that the shaking block 233 drives the shaking circular plate 230 to move upwards. When the extrusion inclined surface 511 on the driving block 291 extrudes the matching inclined surface 501, the shaking circular plate 230 starts to move downwards. In this way, the shaking circular plate 230 continuously moves upwards and downwards;

[0047] The cavity 201 below the partition plate 280 is fixedly installed with a motor 292, the output shaft of the motor 292 penetrates through the partition plate 280 and is connected to the center of the driving circular plate 290, so that the motor 292 can drive the driving circular plate 290 to continuously rotate;

[0048] The limiting groove 202 is arranged along the height direction of the mixing box 100, and the limiting groove 202 limits the limiting plate 232, so that the shaking circular plate 230 can only move up and down along the limiting groove 202;

[0049] The opposite side walls of the cavity 201 are provided with fixed grooves 203, and the side wall of the placement table 110 is fixedly provided with fixed blocks 111 which are opposite to each other and are clamped into the corresponding fixed grooves 203. When the placement table 110 is placed in the cavity 201, the fixed blocks 111 are clamped into the corresponding fixed grooves 203, so as to install the placement table 110 in the cavity 201. Meanwhile, the fixed grooves 203 limit the fixed blocks 111, so that the up and down movement of the placement table 110 is more stable;

[0050] The fixed blocks 111 are provided with fixed holes. When the lower end of the threaded rod 250 is turned out of the threaded cylinder 231, the staff can lift the fixed blocks 111 through the two fixed holes. The lifting of the two fixed blocks 111 can lift the placement table 110, so as to take out the placement table 110 from the cavity 201. At this time, the placement table 110 can be used to transfer a plurality of test tubes;

[0051] When the placement table 110 is being transferred, the lower end of the threaded rod 250 is flush with the lower end surface of the placement table 110, so that the lower end surface of the placement table 110 can be stably placed on the placement surface;

[0052] When the lower end of the threaded rod 250 is not turned out of the threaded cylinder 231, the placement table 110 is moved out of the cavity 201 with the shaking round plate 230, thereby affecting the actual use. The upper end of the limiting groove 202 is fixedly provided with an intercepting plate 234. When the lower end of the threaded rod 250 is not turned out of the threaded cylinder 231, the upward movement of the placement table 110 drives the limiting plate 232 on the shaking round plate 230 to abut against the corresponding intercepting plate 234. At this time, the placement table 110 cannot be moved, and the lower end of the threaded rod 250 needs to be turned out of the threaded cylinder 231, thereby avoiding the situation that the placement table 110 is moved out of the cavity 201 with the shaking round plate 230.

[0053] In actual use, the plurality of test tubes are placed in the corresponding placement groove 211, and then the threaded rod 250 is driven to rotate by the rotating handle 120, so that the threaded rod 250 drives the pressing block 251 to start downward movement. When the pressing block 251 moves downward, the pressing block 251 extrudes the moving block 241, so that the moving block 241 can drive the clamping plate 220 to clamp and fix the test tubes in the placement groove 211 through the moving rod 240. At the same time, the lower end of the threaded rod 250 is inserted into the threaded cylinder 231, and then the driving round plate 290 is driven to rotate by the motor 292, so that the driving block 291 on the driving round plate 290 extrudes the shaking block 233, so that the shaking round plate 230 continuously shakes up and down. The shaking of the shaking round plate 230 drives the placement table 110 to shake through the threaded rod 250, so as to realize the shaking of the placement table 110 to the plurality of test tubes, realize the mixing of the medicine tablet powder and the solution in the plurality of test tubes, and complete the mixing. After mixing, the threaded rod 250 is driven to move upward by the rotating handle 120, so that the clamping plate 220 releases the clamping of the test tubes. At this time, the worker can take out the test tubes from the placement groove 211 and perform subsequent detection.

[0054] In summary, the above only describes the preferred embodiments of the present application, and any changes and modifications made within the scope of the present application should be included in the scope of the present application.

Claims

1. A sample mixing device for pharmaceutical quality detection, comprising a mixing box (100) with a cavity (201) therein, characterized in that: A movable placing table (110) is arranged in the cavity (201), a plurality of placing grooves (211) for placing test tubes are arranged on the placing table (110) in the circumferential direction, clamping plates (220) are arranged in the placing grooves (211), a cavity (212) is arranged at the center position in the placing table (110), a driving assembly is arranged in the cavity (212), and the driving assembly is used for driving the plurality of clamping plates (220) to clamp and fix the test tubes in the placing grooves (211). A liftable shaking disc (230) is arranged in the cavity (201), a shaking assembly is further arranged in the cavity (201), the shaking assembly is used for driving the shaking disc (230) to shake, the driving assembly is further used for connecting the placing table (110) and the shaking disc (230), and the shaking disc (230) drives the placing table (110) to shake.

2. The sample mixing device for pharmaceutical quality testing according to claim 1, characterized in that: A movable rod (240) extending into the cavity (212) at one end is arranged on each clamping plate (220), a movable block (241) is arranged on the movable rod (240) in the cavity (212), and a first inclined surface (300) is arranged on the movable block (241). The driving assembly comprises a threaded rod (250) arranged in the cavity (212) and threaded through the placing table (110) at both ends, an extrusion block (251) is arranged on the threaded rod (250) in the cavity (212), a second inclined surface (252) matched with the plurality of first inclined surfaces (300) is arranged on the side wall of the extrusion block (251), the threaded rod (250) is rotated to drive the extrusion block (251) to extrude the movable block (241), and the clamping plates (220) clamp and fix the test tubes in the placing grooves (211).

3. The sample mixing device for pharmaceutical quality testing according to claim 2, characterized in that: A plurality of support plates (260) for allowing the corresponding movable rods (240) to penetrate therethrough are arranged on the bottom wall of the cavity (212) in the circumferential direction, springs (270) are arranged on the movable rods (240) located on the support plates (260) and the extrusion block (251), and the springs (270) are used for pushing the extrusion block (251) away from the support plates (260).

4. The sample mixing device for pharmaceutical quality testing according to claim 2, characterized in that: A threaded cylinder (231) is arranged on the upper end face of the shaking disc (230), a threaded groove with an upward opening and allowing the lower end of the threaded rod (250) to be threaded inserted is arranged in the threaded cylinder (231).

5. The sample mixing device for pharmaceutical quality testing according to claim 4, characterized in that: Limiting grooves (202) are arranged on the opposite side walls of the cavity (201), limiting plates (232) are arranged on the side walls of the shaking disc (230) in opposition and at one end clamped into the corresponding limiting grooves (202), a plurality of shaking blocks (233) are arranged on the lower end face of the shaking disc (230) in the circumferential direction, a matching inclined surface (501) is arranged on each shaking block (233), and a partition plate (280) is further arranged below the shaking disc (230). The shaking assembly comprises a driving disc (290) arranged on the partition plate (280) and rotatable, a plurality of driving blocks (291) are arranged on the upper end surface of the driving disc (290) in the circumferential direction, and an extrusion inclined surface (511) matched with the matched inclined surface (501) is arranged on each of the driving blocks (291); the driving disc (290) is rotated to drive the driving blocks (291) to extrude the shaking blocks (233), so that the shaking disc (230) drives the placing table (110) to shake.

6. The sample mixing device for pharmaceutical quality testing according to claim 5, characterized in that: The opposite side walls of the cavity (201) are provided with fixing grooves (203), and the side wall of the placing table (110) is provided with fixing blocks (111) opposite to each other and clamped into the corresponding fixing grooves (203).

7. The sample mixing device for pharmaceutical quality testing according to claim 2, characterized in that: The upper end of the threaded rod (250) is provided with a rotating handle (120) for driving the threaded rod (250) to rotate.

Citation Information

Patent Citations

  • Mixing device for sample detection

    CN218422509U