Cell wall breaking ultrasonic equipment
By introducing an adjustment frame and multiple placement boxes into the cell cell disruption ultrasonic device, the problem of convenient placement and removal of cell samples was solved, enabling efficient cell disruption processing for various cell types and improving experimental efficiency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-24
- Publication Date
- 2026-04-07
AI Technical Summary
Existing ultrasonic cell disruption equipment is inconvenient for cell insertion and removal, and is not suitable for disrupting cells of various sizes and types, thus affecting experimental efficiency.
An ultrasonic cell disruption device was designed, comprising an ultrasonic chamber, an outer chamber, an adjustment frame, a lead screw, a knob, a lifting block, and a placement box. The vertical position of the outer chamber can be adjusted by adjusting the lead screw through the knob, thereby driving the lifting block and lifting plate. Combined with the use of multiple placement boxes, it can adapt to different cell sizes and quantities.
It simplifies the insertion and removal of cell samples, improves work efficiency, and can process cell samples of various sizes at the same time to meet different experimental needs.
Smart Images

Figure CN224091876U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of cell disruption technology, specifically to an ultrasonic device for cell disruption. Background Technology
[0002] Cell wall disruption ultrasound equipment is an instrument that uses ultrasound technology to break down cells. It mainly uses the cavitation effect generated by ultrasound in a liquid medium to subject cells to strong shock waves and microjets, thereby breaking down the cell wall and releasing the substances inside the cell.
[0003] However, existing technologies still have the following problems:
[0004] First, existing cell disruption ultrasound equipment is usually inconvenient for inserting and removing cells. Traditional equipment has many limitations in operation, with complex equipment structure design and cumbersome operation procedures. This not only affects experimental efficiency but may also damage cell samples.
[0005] Secondly, most existing ultrasonic cell disruption devices are not suitable for disrupting cells of various sizes and types. When studying different types of microbial and plant / animal cells, the huge differences in cell size and structure may require a lot of time to debug or replace the equipment, which prolongs the experimental cycle. This is especially true when multiple cells need to be processed in batches, which seriously affects experimental efficiency.
[0006] To address the aforementioned problems, the inventors proposed a cell-wall-breaking ultrasonic device. Utility Model Content
[0007] To address the problems of inconvenient cell cell disruption ultrasonic devices in terms of cell insertion and removal, and inconvenience in processing cells of various sizes and types, the purpose of this invention is to provide a cell cell disruption ultrasonic device.
[0008] To solve the above-mentioned technical problems, the present invention adopts the following technical solution: a cell wall breaking ultrasonic device, comprising an ultrasonic box, an outer box being provided inside the ultrasonic box, handles being symmetrically fixed on the upper surface of the outer box, an adjustment frame being fixed on one side of the ultrasonic box, a lead screw being rotatably provided inside the adjustment frame, a knob being rotatably provided on the upper surface of the adjustment frame, the lower end of the knob passing through the adjustment frame and being fixedly connected to the lead screw, a lifting block being threaded onto the outer surface of the lead screw, a support plate being fixed on one side of the lifting block, a lifting plate being fixed on one side of the support plate, and the outer box being placed on the lifting plate.
[0009] Preferably, the outer casing contains a first placement box, a second placement box, and a third placement box. Each of the first, second, and third placement boxes has a limiting strip fixed on one side and a limiting groove on the other side. One side of the inner cavity of the outer casing has a locking strip that works with the limiting groove, and the other side of the inner cavity of the outer casing has a locking groove that works with the limiting strip.
[0010] Compared with the prior art, the beneficial effects of this utility model are as follows:
[0011] 1. This utility model allows for easy operation by adjusting a knob. When cell samples need to be placed into the outer casing, rotating the knob allows the lifting plate to rise smoothly to the appropriate position and accurately deliver the outer casing to the predetermined height. When removing cell samples, simply rotating the knob in the opposite direction allows the outer casing to quickly descend to a convenient operating height. The operation is simple and easy to understand, highly efficient, and enables operators to quickly and accurately place and remove cell samples, significantly improving work efficiency.
[0012] 2. This utility model, through the design of the first placement box, the second placement box and the third placement box, can make reasonable selection according to the size and quantity of cell samples, and can simultaneously perform cell wall breaking work on multiple different cells to meet different experimental needs. Attached Figure Description
[0013] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0014] Figure 1 This is a schematic diagram of the overall structure of this utility model.
[0015] Figure 2 This is a schematic diagram of the overall structure of this utility model from another perspective.
[0016] Figure 3 This is an exploded view of the relevant structure of the adjustment frame and lifting plate of this utility model.
[0017] Figure 4 This is an exploded view of the internal structure of the outer casing of this utility model.
[0018] In the diagram: 1. Ultrasonic box; 2. Adjustment frame; 21. Lead screw; 22. Knob; 23. Limiting post; 24. Lifting block; 25. Support plate; 26. Lifting plate; 27. Limiting plate; 28. Slider; 210. Reinforcing diagonal bar; 3. Outer housing; 31. Handle; 4. First placement box; 41. Second placement box; 42. Third placement box; 43. Limiting strip; 44. Limiting groove; 45. Locking strip; 46. Locking slot. Detailed Implementation
[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0020] Example: Figure 1-4 As shown, this utility model provides a cell wall disruption ultrasonic device, including an ultrasonic chamber 1. The walls of the ultrasonic chamber 1 are made of high-strength, wear-resistant stainless steel, which can not only withstand the pressure from ultrasonic vibrations but also prevent damage to the chamber walls due to long-term friction, ensuring the service life of the chamber. An outer chamber 3 is provided inside the ultrasonic chamber 1. Handles 31 are symmetrically fixed on the upper surface of the outer chamber 3, allowing the outer chamber 3 to be easily removed by pulling up the handles 31. An adjustment frame 2 is fixed on one side of the ultrasonic chamber 1. A lead screw 21 is rotatably installed inside the adjustment frame 2. A knob 22 is rotatably installed on the upper surface of the adjustment frame 2. The lower end of the knob 22 passes through the adjustment frame 2 and is fixedly connected to the lead screw 21. A lifting block 24 is threaded onto the outer surface of the lead screw 21. Limiting posts 23 are symmetrically fixed inside the adjustment frame 2. A lifting block 24 is inserted through the outer casing. A support plate 25 is fixedly mounted on one side of the lifting block 24, and a lifting plate 26 is fixedly mounted on one side of the support plate 25. The outer casing 3 is placed on the lifting plate 26. One side of the support plate 25 is movably fitted to the ultrasonic chamber 1, and both sides of the outer casing 3 are movably fitted to the ultrasonic chamber 1. Rotating the knob 22 causes the lead screw 21 to rotate, as the knob 22 is fixedly connected to the lead screw 21. The lead screw 21 is threadedly connected to the lifting block 24. When the lead screw rotates, the lifting block moves along the axial direction of the lead screw. A limiting post 23 passes through the lifting block, serving as a guide and constraint to ensure that the lifting block can only move up and down along the direction of the limiting post. The lifting block drives the lifting plate 26 to rise or fall through the support plate 25, thereby achieving vertical position adjustment of the outer casing 3 within the ultrasonic chamber 1. This design allows the outer casing 3 to be positioned at different heights inside the equipment, facilitating the placement and removal of cell samples.
[0021] A limiting plate 27 is fixedly installed inside the ultrasonic box 1. A slider 28 is fixedly installed on one side of the lifting plate 26 and is locked inside the limiting plate 27. The slider 28 is rectangular in shape and its size matches the slot on the limiting plate 27. A reinforcing diagonal rod 210 is symmetrically fixed on the lower surface of the adjusting frame 2, and one end of the reinforcing diagonal rod 210 is fixedly connected to the ultrasonic box 1. By sliding the slider 28 inside the limiting plate 27, the lifting stability of the lifting plate 26 is further improved. The reinforcing diagonal rod 210 enhances the connection stability between the adjusting frame 2 and the ultrasonic box 1. When the lifting block drives the lifting plate to rise and fall, the reinforcing diagonal rod can disperse stress and prevent the equipment from deforming due to uneven force.
[0022] The outer box 3 is equipped with a first placement box 4, a second placement box 41, and a third placement box 42. The first placement box 4, the second placement box 41, and the third placement box 42 have the same height, and the width of the first placement box 4 is twice the width of the second placement box 41. The length of the second placement box 41 is twice the length of the third placement box 42. Cell samples are placed in the first placement box 4, the second placement box 41, and the third placement box 4. The placement box is selected appropriately according to the size and quantity of the samples. Larger samples can be placed in the first placement box 4, and smaller samples can be placed in the second placement box 41 or the third placement box 4.
[0023] Each of the first placement box 4, the second placement box 41, and the third placement box 42 has a limiting strip 43 fixedly installed on one side, and a limiting groove 44 opened on the other side. A retaining strip 45, which works in conjunction with the limiting groove 44, is fixedly installed at equal intervals on one side of the inner cavity of the outer box 3. A retaining groove 46, which works in conjunction with the limiting strip 43, is opened at equal intervals on the other side of the inner cavity of the outer box 3. The first placement box 4, the second placement box 41, and the third placement box 4 are engaged with the outer box 3 through the limiting strip 43 and the limiting groove 44. The retaining strip 45 on one side of the inner cavity of the outer box 3 engages with the limiting groove 44 on the placement box, and the retaining groove 46 on the other side engages with the limiting strip 43. This design ensures the stable fixation of the placement box in the horizontal direction, allowing the cell sample to maintain a stable position during ultrasounding and preventing sample damage due to vibration or displacement.
[0024] Working principle: Cell samples are placed in the first placement box 4, the second placement box 41, and the third placement box 4. The placement box is selected appropriately according to the size and quantity of the sample. Larger samples can be placed in the first placement box 4, and smaller samples can be placed in the second placement box 41 or the third placement box 4.
[0025] Rotate knob 22. Since knob 22 is fixedly connected to lead screw 21, the rotation of knob drives lead screw 21 to rotate. Lead screw 21 is threadedly connected to lifting block 24. When lead screw rotates, lifting block moves along the axis of lead screw. Limiting post 23 passes through lifting block, playing a guiding and restraining role, ensuring that lifting block can only move up and down along the direction of limiting post. Lifting block drives lifting plate 26 to rise or fall through support plate 25, thereby realizing the vertical position adjustment of outer box 3 in ultrasonic box 1 to ensure that outer box 3 is in the optimal position in ultrasonic box 1, so that ultrasonic waves can effectively act on the sample.
[0026] Then, the ultrasonic waves are activated, and the ultrasonic device of the ultrasonic chamber 1 is turned on. The ultrasonic waves break down the sample inside the outer chamber 3. During the ultrasonic wave process, the fixed structure of the chamber ensures the stability of the sample and prevents the sample from being damaged due to vibration or displacement.
[0027] Finally, the sample is taken out. After the cell wall breaking process is completed, the lifting plate 26 is lowered to the initial position by rotating the knob 22. The outer box 3 is opened, the placement box is taken out, and the sample is then analyzed or processed.
[0028] Obviously, those skilled in the art can make various modifications and variations to this utility model without departing from its spirit and scope. Therefore, if these modifications and variations fall within the scope of the claims of this utility model and their equivalents, this utility model also intends to include these modifications and variations.
Claims
1. A cell wall disruption ultrasonic device, comprising an ultrasonic chamber (1), characterized in that: The ultrasonic box (1) is provided with an outer box (3). The upper surface of the outer box (3) is symmetrically fixed with handles (31). An adjustment frame (2) is fixed on one side of the ultrasonic box (1). A lead screw (21) is rotatably provided inside the adjustment frame (2). A knob (22) is rotatably provided on the upper surface of the adjustment frame (2). The lower end of the knob (22) passes through the adjustment frame (2) and is fixedly connected to the lead screw (21). A lifting block (24) is threaded onto the outer surface of the lead screw (21). A support plate (25) is fixed on one side of the lifting block (24). A lifting plate (26) is fixed on one side of the support plate (25). The outer box (3) is placed on the lifting plate (26).
2. The cell wall disruption ultrasonic device as described in claim 1, characterized in that: The outer casing (3) is fitted with a first placement box (4), a second placement box (41) and a third placement box (42). Each of the first placement box (4), the second placement box (41) and the third placement box (42) is fixedly provided with a limiting strip (43) on one side. Each of the first placement box (4), the second placement box (41) and the third placement box (42) is provided with a limiting groove (44) on the other side.
3. The cell wall disruption ultrasonic device as described in claim 1, characterized in that: The adjustment frame (2) is symmetrically fixed with limiting posts (23), and the limiting posts (23) penetrate the lifting block (24).
4. The cell wall disruption ultrasonic device as described in claim 1, characterized in that: One side of the support plate (25) is movably attached to the ultrasonic box (1), and both sides of the outer box (3) are movably attached to the ultrasonic box (1).
5. The cell wall disruption ultrasonic device as described in claim 1, characterized in that: The ultrasonic box (1) is fixedly provided with a limiting plate (27), and a slider (28) is fixedly provided on one side of the lifting plate (26), and the slider (28) is locked in the limiting plate (27).
6. The cell wall disruption ultrasonic device as described in claim 1, characterized in that: The lower surface of the adjustment frame (2) is symmetrically fixed with reinforcing diagonal rods (210), and one end of the reinforcing diagonal rods (210) is fixedly connected to the ultrasonic box (1).
7. The cell wall disruption ultrasonic device as described in claim 2, characterized in that: The first placement box (4), the second placement box (41) and the third placement box (42) have the same height, and the width of the first placement box (4) is twice the width of the second placement box (41), and the length of the second placement box (41) is twice the length of the third placement box (42).
8. The cell wall disruption ultrasonic device as described in claim 2, characterized in that: The inner cavity of the outer casing (3) is provided with a locking strip (45) at equal intervals on one side for use with the limiting groove (44), and the inner cavity of the outer casing (3) is provided with a locking groove (46) at equal intervals for use with the limiting strip (43).