Platelet-rich plasma preparation device

Abstract

The platelet-rich plasma preparation device comprises a main body, a storage cavity, a separation cavity, a rotary handle, an upper cover and a lower cover, the storage cavity and the separation cavity are located in the main body, the upper end of the separation cavity is tightly covered and sealed through the upper cover, the lower cover is arranged below the storage cavity, the rotary handle is connected to the bottom end of the storage cavity in a matched mode and used for pushing layered blood in the storage cavity to move from bottom to top, and the separation cavity is internally provided with a plurality of cavities capable of being rotationally switched; when the separation cavity is communicated with the storage cavity, all layers of centrifuged whole blood are sequentially pushed into all cavities corresponding to the separation cavity through the rotating handle. The separator is reliable in structure and good in use performance, a platelet-rich layer, a plasma layer and a red blood cell layer can be completely and independently separated and stored in one separator efficiently, safely, stably and visually through simple rotating operation, red blood cells can be effectively prevented from being mixed into platelets, the recovery rate and efficiency of the platelets are improved, meanwhile, the sealing performance is good, and the service life is long. And mutual pollution between blood and the outside is prevented.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical instrument technical field, concretely relates to a kind of platelet-rich plasma preparation device. BACKGROUND

[0002] With the rapid development of biomedical technology, the research on human blood is also more and more perfect, blood is mainly composed of plasma, platelets, white blood cells and red blood cells, different components have their corresponding important role, and have different medical effects, for example, platelets help the generation of cells, the repair of tissues and the acceleration of wound healing in the patient, but if red blood cells are mixed in platelets, inflammation will occur in the affected area; Therefore, if these components contained in blood can be successfully separated, the effect of auxiliary treatment in medical treatment can be achieved, which can greatly improve the medical effect.

[0003] The common preparation method for separating blood at present is mainly one or two times of centrifugal separation. During centrifugal separation, blood is separated into plasma layer, white membrane layer rich in platelets and red blood cell layer under high-speed rotation. The existing industry mostly adopts the inclined pouring method when extracting each layer, but it is not conducive to the complete separation of each layer during pouring and red blood cells are easily poured out, so that red blood cells are mixed in the white membrane layer, and the efficiency and recovery rate are low. To solve this problem, the patent with publication number CN206853188U discloses a platelet-rich plasma separation and extraction device, which separates each layer of blood through a container and one centrifugal process, but there are still some problems in the operation process, for example, instability, inclination or misalignment caused by improper docking will cause each layer to be mixed, and the safety and stability need to be improved. In addition, the remaining blood in the passage part cannot be seen clearly under the shielding of blood in the separation space part, which will also affect the efficiency of separation and extraction. SUMMARY

[0004] To solve the above technical problems, the utility model provides a platelet-rich plasma preparation device.

[0005] The technical solution for solving the above technical problems is as follows: a platelet-rich plasma preparation device, comprising a main body, a storage cavity, a separation cavity, a rotating handle, an upper cover and a lower cover.

[0006] The storage cavity and the separation cavity are respectively located inside the main body, the upper end of the separation cavity is tightly sealed by the upper cover, the lower cover is arranged below the storage cavity, the rotating handle is connected at the bottom end of the storage cavity and is used to push the layered blood in the storage cavity to move from bottom to top, the lower end of the separation cavity is arranged inside the storage cavity and can be switched to be in communication or occlusion with the storage cavity, the inside of the separation cavity has a plurality of rotatable switching chambers, when the separation cavity is in communication with the storage cavity, each layer of blood after centrifugation is pushed into the corresponding chamber of the separation cavity by the rotating handle in sequence, and a suction hole is formed in the upper cover.

[0007] Further, the inside of the storage cavity is provided with a reversing part, the storage cavity is divided into an upper chamber and a lower chamber by the reversing part, the upper chamber is connected with the separation cavity, the inside of the lower chamber is arranged with a piston which can move along the axial direction, the lower end surface of the piston abuts against the rotating handle, and the piston and the reversing part are used to store blood.

[0008] Further, the upper end surface of the separation cavity is clamped and limited by the upper sealing ring and the upper cover, and the lower sealing ring is used for sealing and connecting between the lower end surface of the separation cavity and the upper end surface of the reversing part.

[0009] Further, the separation cavity comprises a first chamber and a second chamber, the second chamber is sleeved in the first chamber, the outer side wall of the second chamber shares a wall surface with the first chamber or is connected with the side wall of the first chamber through a partition plate, and the first chamber and the second chamber are both provided with through holes in communication with the reversing part.

[0010] Further, the outer wall of the first chamber is sleeved with a hand rotating part through one or more annular longitudinal reinforcing ribs, the outer wall of the first chamber is provided with an indication mark, the lower end surface of the reinforcing rib at the indication mark is provided with an elongated buckle, the buckle is provided with a groove, and the groove is buckled and matched with the clamping column on the storage cavity, so that the chamber can be clamped when the hand rotating part is rotated.

[0011] Further, the reversing part comprises a reversing ring, the upper end surface of the reversing ring is provided with an upper connecting mouth, the lower end surface of the reversing ring is provided with a lower connecting mouth, the upper connecting mouth and the lower connecting mouth are communicated through an eccentric through hole, the upper connecting mouth is respectively connected with the first chamber and the second chamber, and the storage cavity is connected with the lower connecting mouth of the reversing ring.

[0012] Further, the storage cavity is connected with the lower connecting mouth of the reversing ring through a funnel structure with an elongated eccentric hole, and the eccentric hole on the storage cavity is communicated with the eccentric through hole on the reversing ring through a sheath.

[0013] Further, the upper docking mouth is internally provided with a sealing ring, an upper surface of the sealing ring is provided with a clamping block, and the clamping block is matched with a clamping groove arranged on a lower end surface of the separation cavity to realize clamping.

[0014] Further, the commutating ring is provided with a plurality of limiting grooves on a circumferential surface thereof, and the limiting grooves are clamped and matched with limiting columns arranged on an inner wall of the storage cavity.

[0015] Further, an upper connecting end of the storage cavity is movably clamped with the separation cavity, a lower connecting end of the storage cavity is connected with the lower cover provided with the threaded hole in the middle through threads, and the threaded rod of the handle is penetrated through the threaded hole of the lower cover and is in contact with the end surface of the piston.

[0016] The platelet-rich plasma preparation device has the following beneficial effects: the platelet-rich plasma preparation device has reliable structure and good use performance, and can efficiently, safely and stably and visually realize complete independent separation and storage of a platelet-rich layer, a plasma layer and a red blood cell layer in one separator through simple rotation operation, can effectively prevent red blood cells from mixing into platelets, improves the recovery rate and efficiency of platelets, has good sealing performance, and prevents blood and the outside from being mutually contaminated. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 It is a whole structure schematic view of the utility model;

[0018] Figure 2 It is a whole structure cross section schematic view of the utility model;

[0019] Figure 3 It is a separation cavity structure schematic view in the utility model Figure 1 ;

[0020] Figure 4 It is a separation cavity structure schematic view in the utility model Figure 2 ;

[0021] Figure 5 It is a commutating part structure schematic view in the utility model Figure 1 ;

[0022] Figure 6 It is a commutating part structure schematic view in the utility model Figure 2 ;

[0023] Figure 7 It is a commutating part, separation cavity and storage cavity connection schematic view in the utility model;

[0024] Figure 8 It is a storage cavity structure schematic view in the utility model;

[0025] Figure 9 It is an upper cover structure schematic view in the utility model;

[0026] Figures 1 to 9 The reference signs shown in the drawings represent the following: 1 - main body, 2 - storage cavity, 3 - separation cavity, 4 - rotating handle, 5 - upper cover, 10 - lower cover, 6 - reversing part, 7 - piston, 30 - first chamber, 31 - second chamber, 32 - through hole, 33 - hand rotating part, 34 - indication mark, 35 - reinforcing rib, 60 - reversing ring, 61 - upper butt joint nozzle, 62 - lower butt joint nozzle, 63 - eccentric through hole, 64 - sheath, 65 - clamping block, 66 - limiting groove, 68 - clamping groove, 20 - clamping column, 21 - limiting column, 23 - upper connecting end, 24 - lower connecting end, 50 - suction hole, 51 - air hole. DETAILED DESCRIPTION

[0027] The principles and features of the present application are described below in conjunction with the drawings, and the examples are only used to explain the present application and are not intended to limit the scope of the present application.

[0028] As shown in Figures 1 to 2 A platelet-rich plasma preparation device, characterized in that it comprises a main body 1, a storage cavity 2, a separation cavity 3, a rotating handle 4, an upper cover 5 and a lower cover 10. In order to facilitate observation and operation of the whole separation and extraction process, the whole preparation device is preferably made of transparent material, such as inorganic transparent material, organic transparent material or composite transparent material, which can better realize the complete separation of each layer after centrifugation of whole blood.

[0029] The storage cavity 2 and the separation cavity 3 are respectively located inside the main body 1, the storage cavity 2 is used for storing whole blood which has not been centrifuged and separated, and the plasma layer, the white membrane layer rich in platelets and the red blood cell layer which are separated from top to bottom after centrifugation. The upper end of the separation cavity 3 is tightly sealed by the upper cover 5, the lower cover 10 is arranged below the storage cavity 2, the rotating handle 4 is connected to the bottom end of the storage cavity 2 and is used to push the layered blood in the storage cavity 2 to move from bottom to top, the lower end of the separation cavity 3 is arranged inside the storage cavity 2 and can be switched to a communication or occlusion state with the storage cavity 2, and the inside of the separation cavity 3 has a plurality of rotatable switchable chambers.

[0030] The upper connecting end of the storage cavity 2 is movably connected with the separation cavity 3, the lower connecting end of the storage cavity 2 is connected with the lower cover 10 with a threaded hole in the middle through screwing, the threaded rod of the handle 4 passes through the threaded hole of the lower cover 10 and is in contact with the end surface of the piston 7. When the separation cavity 3 is communicated with the storage cavity 2, each layer after centrifugation of whole blood is pushed into the corresponding chamber of the separation cavity 3 in turn by the handle 4, and the upper cover 5 is provided with a suction hole 50. In the state that the lower end of the separation cavity 3 is communicated with the storage cavity 2 to connect the chambers of the separation cavity 3 with the storage cavity 2 respectively, each layer after centrifugation of whole blood is pushed into the corresponding chamber of the separation cavity 3 in turn, and the needed plasma layer and platelet-rich white membrane layer are drawn out through the suction hole provided on the upper cover 5 by using a syringe or pipeline, so that each layer is completely and independently separated, stored and extracted by only one separation cavity 3.

[0031] In addition, the upper cover 5 and the upper sealing ring are provided with a gas permeable hole 51 corresponding to each other, an isolation film is arranged in the gas permeable hole 51 to prevent bacteria from entering and to discharge the gas in the chamber to reduce the pressure in the chamber, the specific material of the isolation film can be medical dialysis paper, and the upper sealing ring can be made of common sealing materials such as rubber ring, silica gel ring and fluorine rubber ring for puncture of a syringe needle; the upper cover 5 is provided with a suction hole corresponding to the through hole of the lower end surface of each chamber of the separation cavity 3, so as to facilitate extraction of each layer completely separated in each chamber of the separation cavity 3, and a hole plug is arranged outside the suction hole to prevent blood from flowing out, and the suction hole is also used for injecting whole blood not separated by centrifugation into the lower chamber of the storage cavity 2 through each through hole by using a syringe.

[0032] The inside of the storage cavity 2 is provided with a reversing part 6, the storage cavity 2 is divided into an upper chamber and a lower chamber by the reversing part 6, the upper chamber is butted against the separation cavity 3, the lower chamber is internally provided with a piston 7 which can move along the axial direction, the lower end surface of the piston 7 is in abutment with the handle 4, and the piston 7 and the reversing part 6 are used for storing blood. The upper end surface of the piston 7 is a plane or a conical surface, the lower end surface of the separation cavity 3 is in sealing abutment with the reversing part 6 through a lower sealing ring. The upper end surface of the separation cavity 3 is clamped and limited by the upper cover 5 through an upper sealing ring, and the lower end surface of the separation cavity 3 and the upper end surface of the reversing part 6 are in sealing butt joint by using a lower sealing ring, so as to reliably increase the sealing property of the separation cavity 3.

[0033] The separation cavity 3 comprises a first chamber 30 and a second chamber 31, the second chamber 31 is sleeved in the first chamber 30, the second chamber 31 is circular or elliptical in cross section, and the outer side wall of the second chamber 31 is co-walled with the first chamber 30 or is connected between the outer side wall of the second chamber 31 and the side wall of the first chamber 30 through a partition plate, so that the two side walls between the first chamber 30 and the second chamber 31 cannot be blocked by blood to form a visible area, through which the separation of each layer of blood can be clearly observed, the operator can adjust the separation progress in time, which helps to improve the efficiency of blood separation. The first chamber 30 and the second chamber 31 are both provided with through holes communicating with the reversing part 6.

[0034] The outer wall of the first chamber 30 is sleeved with a hand rotating part 33 through one or more annular longitudinal reinforcing ribs 35, and the outer wall of the first chamber 30 is provided with an indication mark 34, and the lower end surface of the reinforcing rib 35 at the indication mark 34 is provided with an elongated buckle, and the buckle is provided with a groove, and the groove is buckled with the clamping column 21 on the storage cavity 2, so that the chamber can be clamped when the hand rotating part 33 is rotated.

[0035] The reversing part 6 comprises a reversing ring 60, the upper end surface of the reversing ring 60 is provided with an upper butt joint nozzle 61, the lower end surface of the reversing ring 60 is provided with a lower butt joint nozzle 62, the upper butt joint nozzle 61 and the lower butt joint nozzle 62 are communicated through an eccentric through hole 63, the upper butt joint nozzle 61 is provided with a sealing ring, two through holes are formed in the sealing ring and are respectively connected with the first chamber 30 and the second chamber 31, a clamping block 65 is arranged on the upper surface of the sealing ring, the clamping block 65 is matched with the clamping groove arranged on the lower end surface of the separation cavity 3 to realize clamping, which can prevent the lower sealing ring from falling off from the upper end surface of the reversing part 6 due to rotation when the separation cavity 3 is rotated through the hand rotating part 33 to switch the chamber and change direction.

[0036] A plurality of limiting grooves 66 are formed in the circumferential surface of the reversing ring 60, the limiting grooves 66 are clamped and matched with the limiting columns 20 arranged on the inner wall of the storage cavity 2 to be fixed, which increases the stability of the blood separation and extraction process.

[0037] The storage cavity 2 is connected with the lower butt joint nozzle 62 of the reversing ring 60, specifically, the storage cavity 2 is connected with the lower butt joint nozzle 62 of the reversing ring 60 through a funnel structure with an elongated eccentric hole, and the eccentric hole on the storage cavity 2 is communicated with the eccentric through hole 63 on the reversing ring 60 through a sheath 64, and the sheath 64 plays a connecting and sealing role between the two. The funnel structure with an elongated eccentric hole can prevent the accumulation of liquid, and at the same time, it is more smooth and easier to extract when collecting platelets, and it is less wasteful, and different through holes are arranged corresponding to different chambers to switch and communicate with the eccentric through hole 63 of the reversing ring 60 and the storage cavity 2, so that the separated platelet-rich layer and plasma layer can be more effectively extracted; the nested and stacked structure of the reversing part 6 can simplify the mold and reduce the mold opening cost.

[0038] It should be noted that the chambers of the separation chamber 3 are not limited to two chambers, but also three, and in the present embodiment only two-chamber separation chambers are shown, wherein the first chamber 30 has a larger volume for storing the separated plasma layer, and the second chamber 31 has a smaller volume for storing the separated platelet-rich white membrane layer, and the red blood cell layer continues to be retained in the lower chamber of the storage chamber 2. After the indicator 34 on the separation chamber 3 is rotated to align and lock with the chamber identifier 0 of the storage chamber 2 by rotating the hand grip, the chambers of the separation chamber 3 are completely separated from the eccentric through hole 63 of the commutating ring 60 by the lower sealing ring, and the chambers of the separation chamber 3 are in a closed state. The arrangement of the upper sealing ring, the lower sealing ring, and the isolation membrane can prevent the layers of blood from being contaminated by the outside world, and can also prevent accidental leakage of blood from mixing with each other or contaminating the environment. In other optional embodiments in which the separation part has three chambers, the red blood cell layer is also separated and extracted into one chamber of the separation chamber 3, and can be extracted for use or destroyed as needed.

[0039] In operation, whole blood that has not been centrifugally separated and the plasma layer, the platelet-rich white membrane layer, and the red blood cell layer that are sequentially layered from top to bottom after centrifugal separation are stored in the storage chamber 2. Then, the threaded rod is moved upward by rotating the rotary handle 4, and the piston 7 is moved upward inside the storage chamber 2 to push the blood after centrifugal separation to move upward layer by layer, and each layer flows through the eccentric through hole 63 of the commutating ring 60 and the through hole of the lower sealing ring, and then the rotary separation chamber 3 is switched to different chambers inside, so that each layer is separated into different chambers. By simple rotation operation, the platelet-rich layer, the plasma layer, and the red blood cell layer can be completely and independently stored in different chambers in one instrument, which can effectively prevent red blood cells from mixing with platelets and improve the recovery rate and efficiency of platelets.

[0040] The above is only a preferred embodiment of the present application, and is not intended to limit the present application. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.

Claims

1. A platelet-rich plasma preparation device, characterized by, The application relates to a blood separation device, which comprises a main body (1), a storage cavity (2), a separation cavity (3), a rotating handle (4), an upper cover (5) and a lower cover (10). The storage cavity (2) and the separation cavity (3) are respectively arranged in the main body (1), the upper end of the separation cavity (3) is tightly sealed by the upper cover (5), the lower cover (10) is arranged below the storage cavity (2), the rotating handle (4) is connected to the bottom end of the storage cavity (2) and is used for pushing the layered blood in the storage cavity (2) to move upwards, the lower end of the separation cavity (3) is arranged in the storage cavity (2) and can be switched to be in communication or occlusion with the storage cavity (2), the separation cavity (3) has a plurality of rotatable switchable cavities, when the separation cavity (3) is in communication with the storage cavity (2), each layer of blood after centrifugation is pushed into the corresponding cavity of the separation cavity (3) by the rotating handle (4), and a suction hole (50) is formed in the upper cover (5).

2. The platelet-rich plasma preparation device according to claim 1, wherein The inside of the storage cavity (2) is provided with a reversing part (6), the storage cavity (2) is divided into an upper cavity and a lower cavity by the reversing part (6), the upper cavity is butted against the separation cavity (3), the lower cavity is internally provided with a piston (7) which can move along the axial direction, the lower end surface of the piston (7) abuts against the rotating handle (4), and the piston (7) and the reversing part (6) are used for storing blood.

3. The platelet-rich plasma preparation device according to claim 1, wherein The upper end surface of the separation cavity (3) is clamped and limited by the upper cover (5) through an upper sealing ring, and the lower end surface of the separation cavity (3) is sealed and butted against the upper end surface of the reversing part (6) through a lower sealing ring.

4. The platelet rich plasma preparer of claim 1, wherein, The separation cavity (3) comprises a first cavity (30) and a second cavity (31), the second cavity (31) is sleeved in the first cavity (30), the outer side wall of the second cavity (31) is co-faceted with the first cavity (30) or is connected between the outer side wall of the second cavity (31) and the side wall of the first cavity (30) through a partition plate, and the first cavity (30) and the second cavity (31) are both provided with through holes (32) which are in communication with the reversing part (6).

5. The platelet rich plasma preparer of claim 4, wherein, The outer wall of the first cavity (30) is sleeved with a hand-holding rotating part (33) through one or more annular longitudinal reinforcing ribs (35), the outer wall of the first cavity (30) is provided with an indication mark (34), the lower end surface of the reinforcing rib (35) at the indication mark (34) is provided with an elongated buckle, the buckle is provided with a groove, the groove is buckled and matched with a clamping column (21) on the storage cavity (2), and the cavity can be clamped and fixed when the hand-holding rotating part (33) is rotated.

6. The platelet rich plasma preparer of claim 4, wherein, The reversing part (6) comprises a reversing ring (60), the upper end face of the reversing ring (60) is provided with an upper butt joint nozzle (61), the lower end face of the reversing ring (60) is provided with a lower butt joint nozzle (62), the upper butt joint nozzle (61) and the lower butt joint nozzle (62) are communicated through an eccentric through hole (63), the upper butt joint nozzle (61) is respectively connected with the first cavity (30) and the second cavity (31), and the storage cavity (2) is connected with the lower butt joint nozzle (62) of the reversing ring (60).

7. The platelet rich plasma preparer of claim 6, wherein, The storage cavity (2) is connected with the lower butt joint nozzle (62) of the reversing ring (60) through a funnel structure with an elongated eccentric hole, and the eccentric hole on the storage cavity (2) is communicated with the eccentric through hole (63) on the reversing ring (60) through a sheath (64).

8. The platelet rich plasma preparer of claim 6, wherein, The upper butt joint nozzle (61) is provided with a sealing ring, the upper surface of the sealing ring is provided with a clamping block (65), and the clamping block (65) is matched with a clamping groove (68) arranged on the lower end face of the separation cavity (3) to realize clamping.

9. The platelet rich plasma preparer of claim 6, wherein, The reversing ring (60) is provided with a plurality of limiting grooves (66) on the circumferential surface thereof, and the limiting grooves (66) are clamped and matched with limiting columns (20) arranged on the inner wall of the storage cavity (2).

10. The platelet rich plasma preparer of claim 2, wherein, The upper connecting end (23) of the storage cavity (2) is movably clamped with the separation cavity (3), the lower connecting end (24) of the storage cavity (2) is connected with the lower cover (10) provided with a threaded hole in the middle through screw threads, and the threaded rod of the rotating handle (4) penetrates through the threaded hole of the lower cover (10) and is in contact with the end face of the piston (7).

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