Penetrable cell culture chamber airing device
By designing a perforated plate structure with limiting holes and rotating components, the problems of slow drying speed and group confusion in traditional drying methods were solved, achieving rapid drying without group confusion and improving experimental efficiency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- AFFILIATED HOSPITAL OF JIANGSU UNIV
- Filing Date
- 2025-02-12
- Publication Date
- 2026-04-24
AI Technical Summary
In traditional methods, the drying speed of penetrating cell culture chambers is slow or the groups are easily confused, which affects experimental results and efficiency.
A permeable cell culture chamber drying device was designed, which adopts a perforated plate structure with limiting holes and rotating components. Through the cooperation of the support column and the snap-fit groove, it can achieve rapid drying without mixing of groups.
It enables rapid drying of penetrating cell culture chambers without affecting grouping, is simple to operate, and improves experimental efficiency.
Smart Images
Figure CN224160588U_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the technical field of penetrating cell culture chambers, specifically relating to a drying device for penetrating cell culture chambers. Background Technology
[0002] Permeable cell culture chambers are essential consumables in cell biology experiments, used in co-culture systems, chemotaxis assays, and tumor cell migration and invasion assays. However, all these experiments involve liquid-infiltrated chambers, requiring them to be dried before microscopic imaging to observe results. Traditionally, there are two methods for drying these chambers, but both have the following drawbacks.
[0003] (1) Method 1: Remove the chambers from the well plate and let them dry. The advantage is that they dry quickly, but the disadvantage is that it is easy to mix up the groups of chambers, which affects the analysis of experimental results.
[0004] (2) Method 2: Place it in a well plate to dry. The advantage is that it is not easy to mix up the groups of small chambers. The disadvantage is that the drying speed is slow, which affects the experimental efficiency.
[0005] Therefore, in order to address the above-mentioned technical problems, it is necessary to provide a permeable cell culture chamber drying device.
[0006] The information disclosed in this background section is intended only to enhance the understanding of the overall background of this utility model and should not be construed as an admission or in any way implying that the information constitutes prior art known to those skilled in the art. Utility Model Content
[0007] The purpose of this invention is to provide a drying device for penetrating cell culture chambers, which can shorten the drying time of penetrating cell culture chambers, and at the same time prevent the chamber groups from being mixed up, and is easy to operate.
[0008] To achieve the above objectives, the technical solution provided by a specific embodiment of this utility model is as follows:
[0009] A drying device for a penetrating cell culture chamber, wherein the penetrating cell culture chamber has a limiting hole and includes a perforated plate. The perforated plate has multiple sets of vent holes. A limiting component and a rotating component are respectively arranged on the end face of the perforated plate between the multiple sets of vent holes. The limiting component and the rotating component are symmetrically arranged. A support column is rotatably connected between the limiting component and the rotating component.
[0010] In one or more embodiments of this utility model, a pair of opposite end faces of the bearing column are integrally formed with a snap-fit post, and the pair of opposite end faces of the snap-fit post protrude from the outer end face of the bearing column.
[0011] In one or more embodiments of this utility model, the limiting component includes a buckle, the buckle has a snap-fit groove, and the groove wall of the snap-fit groove snaps into a snap-fit post.
[0012] In one or more embodiments of this utility model, an anti-slip pad is adhered to the end face of the buckle that contacts the snap-fit post, and a plurality of limiting posts that match the vent holes are integrally formed on the bearing post, with the limiting posts located on the end face away from the vent holes.
[0013] In one or more embodiments of this utility model, a pair of opposite end faces of the buckle are integrally formed with a first reinforcing rib, and the buckle and the first reinforcing rib are fixedly connected to one side wall end face of the perforated plate.
[0014] In one or more embodiments of this utility model, the rotating assembly includes a base, which is fixedly connected to one end face of a perforated plate corresponding to the buckle, and a snap-fit post is rotatably connected inside the base.
[0015] In one or more embodiments of this utility model, a rotating groove is provided on the base, and the snap-fit post passes through the rotating groove.
[0016] In one or more embodiments of this utility model, a pair of opposite end faces of the base are integrally formed with a second reinforcing rib, and one side end face of the second reinforcing rib is fixedly connected to the inner wall end face of the perforated plate.
[0017] In one or more embodiments of this utility model, the height of the perforated plate is 1.6-2cm.
[0018] In one or more embodiments of this utility model, heat dissipation grooves are provided on multiple sidewall end faces of the perforated plate.
[0019] Compared with the prior art, the present invention provides a drying device for penetrating cell culture chambers, which can shorten the drying time of penetrating cell culture chambers, and at the same time avoids mixing up the chamber groups, and is simple to operate. Attached Figure Description
[0020] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0021] Figure 1 This is a schematic diagram of the structure of a penetrating cell culture chamber drying device according to Embodiment 1 of this utility model. Figure 1 ;
[0022] Figure 2 This is a schematic diagram of the structure of a penetrating cell culture chamber drying device according to Embodiment 1 of this utility model. Figure 2 ;
[0023] Figure 3 for Figure 2 A schematic diagram of the structure at point A;
[0024] Figure 4 for Figure 2 A schematic diagram of the structure at point B;
[0025] Figure 5 This is a schematic diagram illustrating the usage of a penetrating cell culture chamber drying device according to Embodiment 1 of this utility model. Figure 2 ;
[0026] Figure 6 This is a schematic diagram of the structure of a penetrating cell culture chamber drying device in Embodiment 2 of this utility model. Figure 2 ;
[0027] Explanation of key figure labels:
[0028] 1-Perforated plate, 2-Ventilation hole, 3-Limiting component, 301-First reinforcing rib, 302-Anti-slip pad, 303-Snap fastener, 304-Snap-fit groove, 4-Bearing column, 401-Snap-fit column, 402-Limiting column, 5-Rotating component, 501-Base, 502-Second reinforcing rib, 503-Rotating groove, 6-Heat dissipation groove. Detailed Implementation
[0029] To enable those skilled in the art to better understand the technical solutions of this utility model, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, and not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort should fall within the protection scope of this utility model.
[0030] Example 1
[0031] like Figure 1 As shown, in one embodiment of this utility model, a drying device for a penetrating cell culture chamber is provided. The penetrating cell culture chamber has a limiting hole and includes a perforated plate 1. The perforated plate 1 has multiple sets of vent holes 2. The penetrating cell culture chamber is inserted into the vent holes 2 for drying. This is common knowledge in the field and will not be described in detail here.
[0032] like Figures 1-5As shown, the end face of the perforated plate 1 between multiple sets of vent holes 2 is respectively provided with a limiting component 3 and a rotating component 5. The limiting component 3 and the rotating component 5 are symmetrically arranged. A support column 4 is connected between the limiting component 3 and the rotating component 5. The support column 4 passes through the limiting holes on the penetrating cell culture chamber to fix the penetrating cell culture chamber.
[0033] The height of the well plate 1 is 1.6-2cm, which is higher than that in the prior art, making it easier to dry the permeable cell culture chamber.
[0034] Each pair of opposite end faces of the bearing column 4 is integrally formed with a snap-fit post 401, and each pair of opposite end faces of the snap-fit post 401 protrudes from the outer end face of the bearing column 4. That is, the snap-fit post 401 is fixedly connected to the pair of opposite end faces of the bearing column 4 in parallel, forming an "I" shape.
[0035] like Figures 2-5 As shown, the limiting component 3 further includes a buckle 303, which is adhered to one side wall end face of the perforated plate 1. The buckle 303 has a locking groove 304, and the groove wall of the locking groove 304 engages with the locking post 401. When it is necessary to dry the penetrating cell culture chamber, the supporting post 4 can be rotated until it penetrates the limiting holes of multiple penetrating cell culture chambers, fixing them to the supporting post 4. The bottom of the penetrating cell culture chamber does not contact the box body, and the end face protruding from the perforated plate 1 is more numerous than in conventional technologies, allowing for faster drying and stronger drying stability of the penetrating cell culture chamber, facilitating classification. That is, the supporting post 4 penetrates the limiting holes of the penetrating cell culture chamber without completely leaving the holes, achieving the purpose of rapid drying while maintaining grouping.
[0036] An anti-slip pad 302 is bonded to the end face of the buckle 303 that contacts the snap-fit post 401. The anti-slip pad 302 is made of carbon fiber, nylon, or silicone. The surface of the anti-slip pad 302 is provided with multiple anti-slip textures to enhance friction and improve the stability of the snap-fit post 401 when it is snapped into the buckle 303.
[0037] The support column 4 has multiple limiting columns 402 integrally formed on it, which match the vent holes 2. The limiting columns 402 are located on the side end face away from the vent holes 2. That is, after the support column 4 passes through the limiting holes of the penetrating cell culture chamber in sequence, the penetrating cell culture chamber is located inside the vent holes 2 in sequence. The limiting columns 402 are located on one side end face of the penetrating cell culture chamber to limit it and ensure that the penetrating cell culture chamber is not easy to move.
[0038] Preferably, the limiting post 402 is in the shape of a bamboo joint.
[0039] Specifically, when the penetrating cell culture chamber passes through the limiting post 402, it can pass through with slight force. The limiting post 402 limits the penetrating cell culture chamber. When removing the penetrating cell culture chamber, it can pass through the limiting post 402 with slight force and be taken out.
[0040] Both of the opposite end faces of the buckle 303 are integrally formed with a first reinforcing rib 301. The buckle 303 and the first reinforcing rib 301 are fixedly connected to one side wall end face of the perforated plate 1 to enhance the stability of the buckle 303 fixed on the perforated plate 1.
[0041] The rotating assembly 5 includes a base 501, which is fixedly connected to one side end face of the hole plate 1 corresponding to the buckle 303. The base 501 is rotatably connected to the snap-fit post 401, which rotates within the base 501, thereby controlling the snap-fit post 401 to be fixed and placed on the buckle 303.
[0042] Furthermore, the base 501 has a rotating groove 503 that matches the snap-fit post 401. The snap-fit post 401 passes through the rotating groove 503, so that the bearing post 4 can rotate within the rotating assembly 5.
[0043] The base 501 has a pair of opposite end faces integrally formed with a second reinforcing rib 502, and one end face of the second reinforcing rib 502 is fixedly connected to the inner wall end face of the perforated plate 1. This enhances the stability of the base 501 fixed to the side wall of the perforated plate 1.
[0044] Preferably, a pair of rotating components 5 and limiting components 3 form a group, and the two groups of rotating components 5 and limiting components 3 are symmetrically fixedly connected between the three groups of vent holes 2 located in the middle position of the perforated plate 1. That is, two groups of rotating components 5 and limiting components 3 are respectively provided on the inner wall end face of the perforated plate 1, and a bearing column 4 is connected between the limiting components 3 and the rotating components 5.
[0045] The standard well plate 1 is a 24-well plate with a cap size of 12.5cm x 8.4cm x 0.9cm. A pair of rotating components 5 are installed in the middle of the second and third sets of vent holes 2 corresponding to the well plate 1. The pair of rotating components 5 respectively fasten the support column 4 and extend to the other short side of the well plate 1 with rounded corners. Two limiting components 3 are installed on the other short side corresponding to the rotating components 5. The limiting components 3 can lock or release the support column 4 to fix the permeable cell culture chamber.
[0046] It is worth noting that in practical applications, the number of sets of limiting components 3 and rotating components 5 can be selected to fix the penetrating cell culture chamber according to the number of vent holes 2 set on the well plate 1. For example, if there are 6 vent holes 2, one set of limiting components 3 and rotating components 5 can be set on the side wall end face in the middle position of the well plate 1. If there are 12 vent holes 2, two sets of limiting components 3 and rotating components 5 can be set in the middle position of the two rows of vent holes 2 in the middle position of the well plate 1.
[0047] When using the permeable cell culture chambers, if they need to be dried and sorted, the permeable cell culture chambers that need to be dried can be passed through the support column 4 in sequence and moved to the corresponding vent hole 2 on the support column 4 for drying. After the limiting holes of multiple permeable cell culture chambers pass through the support column 4 in sequence, the support column 4 is moved to the locking groove 304 of the locking buckle 303 of the locking column 401 to fix the support column 4 and start drying the permeable cell culture chambers.
[0048] Example 2
[0049] like Figure 6 Multiple sidewall end faces of the perforated plate 1 shown are provided with heat dissipation grooves 6 to enhance ventilation and increase the drying speed of the penetrating cell culture chamber. The difference between Example 2 and Example 1 is that Example 2 adds heat dissipation grooves 6, which can be selected whether to be provided according to drying requirements to increase ventilation.
[0050] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.
[0051] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.
Claims
1. A drying device for a penetrating cell culture chamber, wherein the penetrating cell culture chamber has a limiting hole, characterized in that, The device includes a perforated plate with multiple sets of ventilation holes. Limiting components and rotating components are respectively provided on the end faces of the perforated plate between the multiple sets of ventilation holes. The limiting components and rotating components are symmetrically arranged, and a bearing column is rotatably connected between the limiting components and the rotating components.
2. The transwell cell culture device drying apparatus of claim 1, wherein, Each of the two opposite end faces of the bearing column is integrally formed with a snap-fit post, and each of the two opposite end faces of the snap-fit post protrudes from the outer end face of the bearing column.
3. A transwell cell culture chamber drying apparatus according to claim 2, wherein, The limiting component includes a buckle with a snap-fit groove, the groove wall of which snaps into a snap-fit post.
4. The transwell cell culture chamber drying device of claim 3, wherein, The end face of the buckle that contacts the snap-fit post is bonded with an anti-slip pad. The bearing post has multiple limiting posts integrally formed on it that match the vent holes. The limiting posts are located on the end face away from the vent holes.
5. The transwell cell culture chamber drying device of claim 3, wherein, The buckle has a first reinforcing rib integrally formed on a pair of opposite end faces, and the buckle and the first reinforcing rib are fixedly connected to one side wall end face of the perforated plate.
6. The transwell cell culture device drying apparatus of claim 4, wherein, The rotating assembly includes a base, which is fixedly connected to one end face of a plate with holes corresponding to the buckle, and a snap-fit post is rotatably connected inside the base.
7. A transwell cell culture chamber drying apparatus according to claim 6, wherein, The base has a rotating groove, and the snap-fit post passes through the rotating groove.
8. The transwell cell culture device drying apparatus of claim 7, wherein, The base has a pair of opposite end faces integrally formed with a second reinforcing rib, and one end face of the second reinforcing rib is fixedly connected to the inner wall end face of the perforated plate.
9. The transwell cell culture device of claim 1 or 8, wherein the device is a transwell cell culture device. The height of the perforated plate is 1.6-2cm.
10. A drying device for a penetrating cell culture chamber according to claim 1 or 8, characterized in that, The perforated plate has heat dissipation grooves on multiple side wall end faces.