PET / CT equipment quality control system

Abstract

The embodiment of the utility model provides a PET / CT (positron emission tomography / computed tomography) equipment quality control system, which is used for correcting PET / CT equipment and comprises a correction solution preparation module, the correction solution preparation module comprises an automatic liquid suction and injection device, a uniform mixing device, a bubble remover and a plurality of correction die bodies, the automatic liquid suction and injection device is used for sucking a correction solution and injecting the correction solution into the uniform mixing device, and the automatic liquid suction and injection device is used for sucking the correction solution and injecting the correction solution into the uniform mixing device; the uniform mixing device is used for uniformly mixing the correction solution, the uniformly mixed correction solution flows into the bubble eliminator, the bubble eliminator is used for eliminating bubbles in the correction solution, and the correction solution after the bubbles are eliminated enters a plurality of correction mold bodies; and the plurality of robots are used for conveying the plurality of correction die bodies to designated positions of PET / CT equipment. Full-process operation such as automatic nuclide injection, solution mixing, bubble elimination, solution conveying, correction data acquisition and equipment running state feedback can be realized, and harm of radionuclides to human bodies in the quality control process is avoided.

Description

Technical Field

[0001] This manual relates to the field of PET / CT equipment quality control technology, specifically to a PET / CT equipment quality control system. Background Technology

[0002] Quality control of PET / CT equipment is a crucial guarantee for nuclear medicine diagnosis and treatment, and is typically achieved through... 18 The F-nuclide positron source is used to perform daily, periodic, and irregular quality control tests and verifications on indicators such as spatial resolution, sensitivity, scattering fraction, noise equivalent count rate, accuracy, time-of-flight resolution, calibration factor, and detector operating status. These quality control efforts can provide a scientific basis for patients' subsequent treatment.

[0003] Currently, quality control activities for PET / CT equipment still rely on manual operation by operators, which means that operators need to come into contact with radioactive materials. Although protective measures such as lead aprons and shielding containers may be taken during operation, the ionizing radiation hazards caused by radioactive materials are ultimately difficult to completely eliminate, and there are risks such as the drop of radioactive drugs or accidental negligence and violation of regulations that may lead to unexpected radiation safety hazards. Summary of the Invention

[0004] In view of this, the embodiments of this specification provide a quality control system for PET / CT equipment, which can realize the entire process of automatic injection of radionuclides, mixing of solutions, elimination of air bubbles, transportation of solutions, acquisition of calibration data, and feedback of equipment operating status, thereby avoiding harm to the human body from radionuclides during the quality control process.

[0005] This specification provides the following technical solution through its embodiments: a PET / CT equipment quality control system for calibrating PET / CT equipment, the system comprising:

[0006] The calibration solution preparation module includes an automatic liquid aspiration and injection device, a mixing device, a defoamer, and several calibration molds. The automatic liquid aspiration and injection device is used to aspirate the calibration solution and inject it into the mixing device. The mixing device mixes the calibration solution. The mixing device is connected to the defoamer so that the mixed calibration solution flows into the defoamer. The defoamer eliminates air bubbles in the calibration solution. The calibration solution after defoaming is filled into several calibration molds.

[0007] The transport module includes several robots, which are used to transport several calibration phantoms to a designated location on the PET / CT equipment.

[0008] Preferably, the correction solution includes 18 A mixture of F radionuclide and water.

[0009] Preferably, the system further includes a monitoring module, which includes a monitoring unit for monitoring the robot's running trajectory.

[0010] Preferably, the monitoring module further includes a control unit for controlling the robots and the PET / CT devices.

[0011] Preferably, the robot is wirelessly connected to the PET / CT device.

[0012] Preferably, the wireless connection between the robot and the PET / CT device includes: the robot connecting to the PET / CT device via a WiFi / 5G module.

[0013] Preferably, the number of robots is the same as the number of calibration phantoms.

[0014] Preferably, the number of robots is the same as the number of PET / CT devices.

[0015] Compared with the prior art, the beneficial effects that at least one technical solution adopted in the embodiments of this specification can achieve include at least:

[0016] It can automatically inject radionuclides, mix solutions, eliminate air bubbles, transport solutions, acquire calibration data, and provide feedback on equipment operating status, thus avoiding harm to the human body from radionuclides during quality control. Attached Figure Description

[0017] To more clearly illustrate the technical solutions of the embodiments of this application, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the PET / CT equipment quality control system provided in this application.

[0019] In the diagram, 1 is the calibration solution preparation module; 101 is the automatic liquid aspiration and injection device; 102 is the mixing device; 103 is the defoamer; 104 is the calibration phantom; 2 is the delivery module; 3 is the PET / CT equipment; and 4 is the monitoring module. Detailed Implementation

[0020] The embodiments of this application will now be described in detail with reference to the accompanying drawings.

[0021] The following specific examples illustrate the implementation of this application. Those skilled in the art can easily understand other advantages and effects of this application from the content disclosed in this specification. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. This application can also be implemented or applied through other different specific embodiments, and the details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of this application. It should be noted that, in the absence of conflict, the following embodiments and features in the embodiments can be combined with each other. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0022] It should be noted that various aspects of embodiments within the scope of the appended claims are described below. It will be apparent that the aspects described herein can be embodied in a wide variety of forms, and any particular structure and / or function described herein is merely illustrative. Based on this application, those skilled in the art will understand that one aspect described herein can be implemented independently of any other aspect, and two or more of these aspects can be combined in various ways. For example, any number and aspects set forth herein can be used to implement the device and / or practice the method. Additionally, this device and / or method can be implemented using structures and / or functionalities other than one or more of the aspects set forth herein.

[0023] It should also be noted that the illustrations provided in the following embodiments are only schematic representations of the basic concept of this application. The drawings only show the components related to this application and are not drawn according to the actual number, shape and size of the components in the actual implementation. In the actual implementation, the form, quantity and proportion of each component can be arbitrarily changed, and the layout of the components may also be more complex.

[0024] Furthermore, specific details are provided in the following description to facilitate a thorough understanding of the examples. However, those skilled in the art will understand that the described aspects can be practiced without these specific details.

[0025] Currently, the main problems in the quality control of PET / CT equipment are as follows:

[0026] Insufficient radiation hazard control measures in the quality control testing process: Currently, the quality control index testing of PET / CT equipment is mainly carried out by relevant personnel operating at close range; however, since the interaction between positrons and the outer electrons of the atomic nuclei of surrounding matter produces 511 keV annihilation radiation rays, it will inevitably cause varying degrees of harm to quality control personnel.

[0027] liquid 18 The preparation process of the F-quality control source is unstable: through...18 When F nuclide is mixed with water to prepare a quality control source, the uniformity of its distribution within the container and the generation of bubbles have a significant impact on the reliability of the quality control test data.

[0028] Terminology Explanation: 1. 18 F: Also known as F-18 or Fluorine-18. It is an isotope of fluorine, whose atomic nucleus is unstable and readily emits positrons, thus exhibiting radioactivity.

[0029] 2. PET / CT: Positron Emission Tomography / Computed Tomography. PET-CT integrates PET and CT, with PET providing detailed functional and metabolic molecular information about lesions, while CT provides precise anatomical localization of lesions. A single imaging session can obtain tomographic images of the entire body from all directions.

[0030] The technical solutions provided by the various embodiments of this application are described below with reference to the accompanying drawings.

[0031] like Figure 1 As shown, a PET / CT equipment quality control system is used for calibrating PET / CT equipment 3. The system includes:

[0032] The calibration solution preparation module 1 includes an automatic liquid aspiration and injection device 101, a mixing device 102, a defoamer 103, and several calibration molds 104. The automatic liquid aspiration and injection device 101 is used to aspirate the calibration solution and inject it into the mixing device 102. The mixing device 102 mixes the calibration solution. The mixing device 102 is connected to the defoamer 103 so that the mixed calibration solution flows into the defoamer 103. The defoamer 103 eliminates air bubbles in the calibration solution. The calibration solution after eliminating air bubbles is filled into several calibration molds 104.

[0033] The conveying module 2 includes several robots, which are used to convey several calibration phantoms 104 to a designated location on the PET / CT device 3.

[0034] The automatic aspiration and injection device 101 is responsible for aspirating the calibration solution (typically containing...) 18The calibration solution (containing the nuclide and water) is injected into a mixing device 102. The mixing device 102 thoroughly mixes the injected calibration solution to ensure uniform distribution of the nuclide within the solution. The mixed calibration solution flows into a defoamer 103, which eliminates air bubbles to prevent them from affecting the reliability of subsequent quality control test data. The bubble-free calibration solution is then filled into several calibration phantoms 104, which will subsequently be used for calibration testing of the PET / CT equipment 3. The system is equipped with several robots, each responsible for transporting one or more calibration phantoms 104 from the preparation area to the designated location on the PET / CT equipment 3.

[0035] The data acquisition and analysis process is as follows:

[0036] Initiating the calibration procedure: After the calibration phantom 104 is transported to the designated position, the monitoring personnel initiate the calibration procedure through the control interface of the PET / CT equipment 3.

[0037] Data Measurement: The PET / CT device 3 measures the calibration phantom 104 to obtain relevant quality control data (such as spatial resolution, sensitivity, etc.).

[0038] Data Acquisition and Analysis: The robot acquires measurement data from the PET / CT device 3 via a Wi-Fi / 5G module; the system automatically analyzes and evaluates the data using built-in algorithms to determine the status of the PET / CT device 3.

[0039] Feedback and Adjustment: Based on the data analysis results, the system automatically sets equipment status adjustment parameters; monitoring personnel or the system make necessary adjustments to the PET / CT equipment 3 according to these parameters to ensure that the image quality meets the requirements.

[0040] Fully automated operation: Enables fully automated operation from calibration solution preparation to data acquisition and analysis, reducing manual intervention and improving work efficiency.

[0041] Avoid radiation damage: Operators do not need to directly contact radioactive nuclides, effectively avoiding harm to the human body from radioactive nuclides during quality control.

[0042] Improve the reliability of quality control data: By using the mixing device 102 and the defoamer 103, the uniformity and bubble-free state of the calibration solution are ensured, thereby improving the reliability of quality control test data.

[0043] Supports collaborative work of multiple devices: The system supports collaborative work of multiple calibration phantoms 104 and robots, which can meet the calibration needs of multiple PET / CT devices 3 in the hospital and further improve calibration efficiency.

[0044] Intelligent adjustment: Based on data analysis results, the system automatically sets equipment status adjustment parameters to achieve intelligent adjustment and optimization of the PET / CT equipment 3.

[0045] like Figure 1 As shown, in some embodiments, the correction solution includes 18 A mixture of F radionuclide and water. 18 F nuclide (such as 18 FDG (F-FDG) is a commonly used radioactive tracer in PET / CT imaging. The calibration solution formed by mixing it with water can simulate the characteristics of glucose metabolism in the human body, ensuring that the metabolic signals captured by the equipment during the calibration process are highly consistent with the actual imaging conditions. By matching the actual imaging scene, the quantitative analysis capability of PET / CT on the distribution of radioactivity can be verified, reducing the impact of equipment errors on subsequent clinical diagnosis. 18 The F nuclide has a short half-life, which can reduce radioactive residues while meeting calibration requirements.

[0046] like Figure 1 As shown, in some embodiments, the system further includes a monitoring module 4, which includes a monitoring unit for monitoring the robot's trajectory. The monitoring unit ensures that the correction phantom 104 is accurately delivered to the designated imaging area of ​​the PET / CT device 3 by monitoring the robot's movement trajectory in real time.

[0047] like Figure 1 As shown, in some embodiments, the monitoring module 4 further includes a control unit for controlling several robots and several PET / CT devices 3. The robots transport the calibration phantom 104 to a designated location on the PET / CT device 3, and the monitoring personnel initiate the device calibration program through the control unit to perform calibration operations on the PET / CT device 3.

[0048] like Figure 1 As shown, in some embodiments, the robot is wirelessly connected to the PET / CT device 3.

[0049] like Figure 1As shown, in some embodiments, the wireless connection between the robot and the PET / CT device 3 includes: the robot connecting to the PET / CT device 3 via a WiFi / 5G module. The robot acquires measurement data via the Wi-Fi / 5G module, automatically analyzes and evaluates the data using algorithms, and determines the state adjustment parameters of the PET / CT device 3 to ensure image quality meets requirements. The robot establishes a wireless communication connection with the PET / CT device 3 via its built-in Wi-Fi / 5G module. After the PET / CT device 3 completes its calibration procedure, the robot receives the measurement data transmitted by the device via the Wi-Fi / 5G network. This data includes key indicators such as the device's spatial resolution, sensitivity, scattering fraction, noise equivalent count rate, accuracy, time-of-flight resolution, calibration factor, and detector operating status.

[0050] It should be noted that the robot's built-in data processing unit uses pre-defined algorithms to analyze the received measurement data. These algorithms can identify outliers, trends, and patterns in the data, thereby evaluating the performance indicators of the PET / CT device 3. The analysis process is based on pre-defined evaluation criteria, which are developed according to industry standards and clinical needs, to determine whether the image quality and overall performance of the PET / CT device 3 meet the requirements. Based on the results of the data analysis, the robot automatically generates state adjustment parameters for the PET / CT device 3. These parameters are designed to optimize the device's performance and ensure that image quality meets clinical use standards. The robot transmits the generated adjustment parameters back to the PET / CT device 3 via a Wi-Fi / 5G module, and the device automatically adjusts itself according to these parameters to improve image quality and overall performance.

[0051] like Figure 1 As shown, in some embodiments, the number of robots is the same as the number of calibration phantoms 104; the number of robots is the same as the number of PET / CT devices 3. Hospitals typically have several PET / CT devices 3, so the system supports multiple calibration phantoms 104 and robots working together to improve calibration efficiency.

[0052] The following description outlines the automatic liquid aspiration and injection device, mixing device, defoamer, and several calibration molds that can be used to facilitate implementation by those skilled in the art:

[0053] Automatic liquid aspiration and injection devices can employ the following devices.

[0054] Precision peristaltic pump: By precisely controlling the pump's speed and direction of rotation, it enables accurate aspiration and quantitative injection of the calibration solution, avoiding liquid leakage and errors.

[0055] Injection pump: Suitable for high-precision liquid transfer, with adjustable injection speed and volume to ensure accurate injection of calibration solution into the mixing device.

[0056] The mixing device can be the following:

[0057] Magnetic stirrer: Uses a magnetic field to drive a magnetic stirrer to quickly and evenly stir the solution, ensuring... 18 The F nuclide was thoroughly mixed with water.

[0058] Vortex mixer: It generates vortexes through high-speed rotation, so that the solution can be uniformly mixed in a short time. It is suitable for scenarios that require rapid mixing.

[0059] Defoamers can be made using the following devices.

[0060] Ultrasonic defoamer: It uses ultrasonic vibration to break down the bubble structure in a liquid, effectively eliminating bubbles in the mixed liquid and improving the reliability of quality control test data.

[0061] Vacuum defoamer: By creating a vacuum environment, it reduces the content of dissolved gases in the liquid, thereby reducing the formation of bubbles. It is suitable for occasions where high defoaming effect is required.

[0062] The following devices can be used to correct the phantom.

[0063] Standard phantoms: Possessing known physical and chemical properties, these phantoms are used to simulate the response of human tissue to PET / CT equipment, ensuring the accuracy and repeatability of quality control tests.

[0064] Customized phantoms: Based on the specifications and testing requirements of specific PET / CT equipment, we design and manufacture phantoms of specific shapes and sizes to meet personalized quality control requirements.

[0065] The same or similar parts between the various embodiments in this specification can be referred to mutually. Each embodiment focuses on describing the differences from other embodiments. In particular, the method embodiments described later are relatively simple in description since they correspond to the system, and relevant parts can be referred to the descriptions in the system embodiments.

[0066] The above description is merely a specific embodiment of this application, but the scope of protection of this application is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this application should be included within the scope of protection of this application. Therefore, the scope of protection of this application should be determined by the scope of the claims.

Claims

1. A quality control system for PET / CT equipment, characterized in that, The system for calibrating PET / CT equipment includes: The calibration solution preparation module includes an automatic liquid aspiration and injection device, a mixing device, a defoamer, and several calibration molds. The automatic liquid aspiration and injection device is used to aspirate the calibration solution and inject it into the mixing device. The mixing device mixes the calibration solution. The mixing device is connected to the defoamer so that the mixed calibration solution flows into the defoamer. The defoamer eliminates air bubbles in the calibration solution. The calibration solution after defoaming is filled into several calibration molds. The transport module includes several robots, which are used to transport several calibration phantoms to a designated location on the PET / CT equipment.

2. The PET / CT equipment quality control system according to claim 1, characterized in that, The calibration solution includes 18 A mixture of F radionuclide and water.

3. The PET / CT equipment quality control system according to claim 1, characterized in that, The system also includes a monitoring module, which includes a monitoring unit used to monitor the robot's running trajectory.

4. The PET / CT equipment quality control system according to claim 3, characterized in that, The monitoring module also includes a control unit, which is used to control several of the robots and several of the PET / CT devices.

5. The PET / CT equipment quality control system according to any one of claims 1-4, characterized in that, The robot is wirelessly connected to the PET / CT equipment.

6. The PET / CT equipment quality control system according to claim 5, characterized in that, The wireless connection between the robot and the PET / CT device includes: the robot connecting to the PET / CT device via a WiFi / 5G module.

7. The PET / CT equipment quality control system according to any one of claims 1-6, characterized in that, The number of robots is the same as the number of calibration phantoms.

8. The PET / CT equipment quality control system according to any one of claims 1-6, characterized in that, The number of robots is the same as the number of PET / CT devices.

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