Proton helium ion treatment device

By combining a cone-beam CT system with a rotating gantry and an integrated scanning magnet solution with a six-dimensional treatment bed, high-precision positioning and compact design of the proton-helium ion therapy device were achieved, solving the problems of range error and tumor positioning error in particle therapy and meeting the needs of high-performance particle therapy.

CN224180116UActive Publication Date: 2026-05-01SHANGHAI ADVANCED RES INST CHINESE ACADEMY OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SHANGHAI ADVANCED RES INST CHINESE ACADEMY OF SCI
Filing Date
2025-05-29
Publication Date
2026-05-01

AI Technical Summary

Technical Problem

Existing proton-helium ion therapy devices have shortcomings in terms of positioning accuracy and device compactness. In particular, the problems of range error and tumor positioning error in particle therapy have not been effectively solved.

Method used

Employing a cone-beam CT system based on a rotating gantry and an integrated scanning magnet solution, combined with a six-dimensional treatment bed, it achieves high-precision positioning and device compactness. Multi-angle intensity-modulated therapy is performed through a 360-degree rotating gantry, and proton or helium ion radiotherapy is selected.

Benefits of technology

It improves the positioning accuracy and device compactness of proton-helium ion therapy, solves the positioning error problem in particle therapy, and meets the high-performance needs of different cancer treatment centers and patients.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a proton helium ion treatment device. The proton helium ion treatment device comprises an injector, an accelerator, a rotating rack, a treatment head, a beam distribution system and a six-dimensional treatment bed which are sequentially arranged along the transportation direction of a beam. The injector comprises a hydrogen ion source and a helium ion source which can be switched; the treatment head and beam distribution system comprises an integrated scanning magnet, a position ionization chamber, a dose ionization chamber, a ridge-shaped filter and a range shifter which are installed on a treatment head support and sequentially arranged in the beam conveying direction, and the integrated scanning magnet is used for beam deflection in the transverse X direction and the transverse Y direction at the same time. A cone beam CT system is further fixedly installed on the rotating rack, and precise positioning and positioning correction of a patient are achieved in combination with the six-dimensional mechanical arm treatment bed. The proton helium ion treatment device can meet the requirement for high precision of patient positioning in ion treatment, ion treatment with optional proton helium ions can be achieved, and the treatment system is more compact through the design of the integrated scanning magnet.
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Description

A proton-helium ion therapy device Technical Field

[0001] This invention belongs to the field of particle radiotherapy, specifically relating to a proton-helium ion therapy device for high-precision tumor localization, enabling more effective and safer radiotherapy for patients. Background Technology

[0002] Particle therapy is one of the most advanced cancer treatments in the world. Compared to traditional photon radiotherapy, particle irradiation creates a peak dose at the end of its range after entering the patient's body, known as the Bragg peak effect. By precisely controlling the particle beam energy and beam spot position, most of the dose can be concentrated within the tumor target area, while minimizing the dose to surrounding normal tissues. Particle therapy has advantages such as short treatment cycles, precise targeting, high cure rates, and few side effects. In ion radiotherapy systems, irradiation techniques typically fall into two main categories: scattered irradiation and scanning irradiation. The irradiation technique used in this invention is scanning irradiation. Helium ions, with a mass between protons and carbon ions, possess both the advantage of no tailing at the end of the range, as seen in proton therapy, and the ability to kill cancer cells with a high LET (Leakage Tolerance). From 1975 to 1993, Lawrence Berkeley National Laboratory in the United States conducted research on cancer treatment using wide-beam helium ions, treating a total of 2054 patients. In August 2020, the Heidelberg Ion Beam Therapy Center in Germany treated the first patient with helium ion therapy, subsequently initiating clinical trials to evaluate the efficacy and safety of helium ion therapy.

[0003] Ion therapy is characterized by concentrated doses and strong lethality, so precise patient positioning before treatment is crucial.

[0004] Before ion therapy, the patient is usually initially positioned using a six-dimensional robotic arm treatment bed and laser lamp positioning system. Precise positioning and verification are then performed using positioning technologies such as surface image guidance, orthogonal DR imaging, cone-beam CT (CBCT), and sliding-rail CT.

[0005] Therefore, a new proton-helium ion therapy device is needed to address the range error caused by this conversion. Summary of the Invention

[0006] The purpose of this invention is to provide a proton-helium ion therapy device that meets the high precision requirements for positioning in ion therapy, and the device is compact.

[0007] To achieve the above objectives, this utility model provides a proton-helium ion therapy device, comprising an injector, an accelerator, a rotating gantry, a treatment head and a beam delivery system, and a six-dimensional treatment bed arranged sequentially along the beam transport direction. A cone-beam CT system is also fixedly installed on the rotating gantry.

[0008] The injector includes a switchable hydrogen ion source and a helium ion source; the treatment head and beam delivery system include an integrated scanning magnet, a position ionization chamber, a dose ionization chamber, a ridge filter, and a range shifter, which are mounted on the treatment head support and arranged sequentially along the beam transport direction. The integrated scanning magnet is also used for beam deflection in the transverse XY direction.

[0009] The integrated scanning magnet has a vacuum box and a vacuum window, and is connected to a scanning power supply to drive the magnetic field of the scanning magnet.

[0010] The position ionization chamber is a multi-wire ionization chamber; the dose ionization chamber includes a main dose ionization chamber and a secondary dose ionization chamber, the secondary dose ionization chamber providing redundant measurement of the irradiation dose; the ridge filter is used to extend the Bragg peak width of the beam.

[0011] The range shifter is connected to the treatment head support via a treatment head telescopic mechanism to make the distance from the scanning magnet to the range shifter adjustable.

[0012] The cone-beam CT system is switchable between cone-beam CT imaging mode and orthogonal DR imaging mode; the cone-beam CT system includes two sets of mutually orthogonal CT imaging components, each set of CT imaging components including an X-ray tube fixedly mounted on a rotating gantry and a flat panel detector fixedly mounted on one side of the treatment head.

[0013] Each X-ray tube is sequentially connected to a high-voltage generator, a synchronization controller, and a computer. Two synchronization controllers are simultaneously connected to the exposure control box, and a beam limiter and a butterfly filter are installed at the front end of the X-ray tube's exit. The X-ray central axis of the tube is perpendicularly centered relative to the detection surface of the flat panel detector and passes through the isocenter point of the rotating frame.

[0014] The six-dimensional treatment bed includes a control cabinet, a six-axis robotic arm electrically connected to the control cabinet, and a treatment bed board connected to the end of the six-axis robotic arm. The treatment bed board is made of carbon fiber.

[0015] This invention employs cone-beam CT positioning technology based on a rotating gantry. During the positioning process, multi-angle cone-beam CT imaging can be performed via a 360-degree rotating gantry. Cone-beam CT positioning offers advantages such as three-dimensional imaging, high-quality soft tissue imaging, and high positioning accuracy. Furthermore, the rotating gantry-based cone-beam CT allows for imaging and positioning at the treatment position, reducing additional deviations caused by non-treatment position positioning techniques, simplifying the treatment process, and thus making the positioning accuracy of proton and helium ion therapy more precise and effective. The integrated scanning magnet design effectively shortens the source axis distance, making the treatment head more compact and facilitating the installation of the cone-beam CT system. The cone-beam CT system is used in conjunction with a six-dimensional robotic arm treatment bed to achieve precise patient positioning and alignment.

[0016] Furthermore, this invention allows for the selection of orthogonal DR or cone-beam CT for localization based on clinical conditions. Cone-beam CT provides high-precision localization of the tumor target area, offering higher positioning accuracy and generating clearer three-dimensional images, facilitating oncologists' assessment of the localization results. Orthogonal DR, on the other hand, offers advantages such as faster localization speed and lower requirements for the treatment bed angle, thus compensating for localization scenarios where cone-beam CT imaging cannot be performed due to treatment bed misalignment.

[0017] This invention selects protons and helium ions for radiotherapy based on clinical needs, and can perform multi-angle intensity-modulated therapy through a 360-degree rotating gantry. It solves the problems of positioning errors in particle therapy and the immunity of hypoxic tumors to proton therapy, and can meet the needs of different cancer treatment centers and patients for particle therapy with better performance. Attached Figure Description

[0018] Figure 1 is a schematic diagram of the proton-helium ion therapy system based on cone-beam CT imaging of this invention.

[0019] Figure 2 is a structural diagram of the treatment head and beam delivery system of the proton-helium ion therapy system of this utility model.

[0020] Figure 3 is a schematic diagram of the integrated scanning magnet.

[0021] Figure 4 is a structural block diagram of the electrical component of the cone-beam CT system of the proton-helium ion therapy system of this invention.

[0022] Figure 5 is a structural diagram of the six-dimensional treatment bed of the proton-helium ion therapy system of this utility model. Detailed Implementation

[0023] The preferred embodiments of this utility model are given below with reference to the accompanying drawings and described in detail.

[0024] As shown in Figures 1 and 2, the proton-helium ion therapy device of this invention includes an injector, an accelerator, a rotating gantry 10, a treatment head and beam delivery system 30, and a six-dimensional treatment bed 40, arranged sequentially along the beam transport direction. A cone-beam CT system 20 is also fixedly mounted on the rotating gantry 10. Based on existing proton-helium ion therapy devices, this invention adds a cone-beam CT system based on an existing rotating gantry within the rotating gantry, thus achieving cone-beam CT positioning functionality. Through the fusion design of the cone-beam CT rotating mechanism and the treatment rotating gantry, cone-beam CT scanning and treatment for proton-helium ions are realized.

[0025] The rotating gantry 10 is a compact 360-degree rotating gantry, providing high-precision rotational conditions for proton-helium ion intensity-modulated therapy (IMRT). The structure of the compact 360-degree rotating gantry is basically the same as existing rotating gantry structures, except that weight is reduced through mechanical optimization, thus providing high-precision continuous rotation conditions of up to 6° / s for cone-beam CT imaging. During the positioning phase, the rotating gantry 10 can be used in conjunction with a cone-beam CT system for cone-beam CT imaging or orthogonal DR imaging. During the treatment phase, it is used to adjust the treatment head for irradiation at different treatment angles.

[0026] The treatment head and beam delivery system 30 includes a vacuum flange 37, an integrated scanning magnet 31 mounted on the treatment head support and arranged sequentially along the beam transport direction, a position ionization chamber 32, a dose ionization chamber 33, a ridge filter 34, and a range shifter 35. The range shifter 35 is connected to the treatment head support via a treatment head telescopic mechanism to adjust the distance from the scanning magnet to the range shifter 35, reducing the influence of beam spot diffusion. In this embodiment, the range shifter 35 is made of plexiglass with a thickness of 2 cm or 4 cm.

[0027] The integrated scanning magnet 31 is also used for beam deflection in the transverse XY direction, which significantly shortens the source axis distance, thereby enabling point scanning or continuous scanning irradiation.

[0028] The specific structure of the integrated scanning magnet 31 can be found in the patent document with application publication number 119925833, as shown in Figure 3. The integrated scanning magnet 31 includes a scanning magnet frame 313 and coil windings 314 in the XY directions. The material of the scanning magnet frame 313 is a high-temperature resistant and corrosion-resistant engineering plastic.

[0029] This invention adopts an integrated scanning magnet scheme based on the traditional discrete scanning magnet. It replaces the two discrete secondary magnets in the X and Y directions with two integrated coil windings, which significantly shortens the length of the scanning magnet in the beam direction, making the treatment head more compact. This is more conducive to the installation of cone-beam CT system and the improvement of imaging quality, and also reduces the building space of the treatment room. Furthermore, by applying a specified current to the coil windings 314 in the X and Y directions, a magnetic field is generated, which deflects the beam and directs it to the target position.

[0030] The integrated scanning magnet 31 also includes a vacuum chamber 311 and a vacuum window 312 located on its central axis, and is connected to a scanning power supply (not shown) to drive the magnetic field required for the formation of the scanning magnet. In this invention, the integrated scanning magnet 31 requires two scanning power supplies, one controlling the deflection degree in the X direction and the other controlling the deflection degree in the Y direction. Both the X and Y directions are perpendicular to the beam transport direction and are perpendicular to each other.

[0031] The injector includes a switchable hydrogen ion source and a helium ion source. Specifically, the control system can switch the required ion source to generate the target ion. Thus, proton or helium ion therapy can be selected according to the patient's indications, or mixed ion therapy can be performed (the order of irradiation is set by the treatment plan). Most solid tumors can be treated with proton therapy, while helium ion therapy is used for tumor types with radioresistance.

[0032] The position ionization chamber 32 is used for real-time beam position measurement, and it is preferably a multi-wire ionization chamber. The irradiation technology used in this invention is fast scanning irradiation technology. The position ionization chamber has a poor signal-to-noise ratio at high sampling rates, making it difficult to use traditional strip ionization chambers for position measurement. Therefore, multi-wire proportional ionization chamber technology is used, and the primary signal is amplified by avalanche to obtain a position measurement signal with a high signal-to-noise ratio. The position measurement signal is then Gaussian fitted to obtain the beam spot position and size, thereby achieving a high signal-to-noise ratio position measurement.

[0033] The dose ionization chamber 33 is used for dose control and dose monitoring, and preferably includes a main dose ionization chamber and a secondary dose ionization chamber. The position ionization chamber 32 monitors the position of ions in real time. The main dose ionization chamber of the dose ionization chamber 33 accurately measures the irradiation dose, and the secondary dose ionization chamber provides redundant measurement of the irradiation dose. Thus, the secondary dose ionization chamber uses the redundant measurement results for dose monitoring, and any unexpected deviation from the measurement results of the main dose ionization chamber immediately triggers an interlock to stop irradiation.

[0034] Ridge filter 34 is used to extend the Bragg peak width of the beam.

[0035] As shown in Figures 1 and 4, the cone-beam CT system 20 is switchable between cone-beam CT imaging mode and orthogonal DR imaging mode. The cone-beam CT system 20 includes two sets of mutually orthogonal CT imaging components. Each set of CT imaging components includes an X-ray tube 21 fixedly mounted on the rotating gantry 10 and a flat panel detector 22 fixedly mounted on one side of the treatment head. The flat panel detectors 22 of the two sets of CT imaging components are mechanically mounted on both sides of the treatment head and the beam delivery system 30. Thus, the cone-beam CT system 20 can perform cone-beam CT imaging in conjunction with the rotation of the rotating gantry 10.

[0036] Each X-ray tube 21 is sequentially connected to a high-voltage generator 23, a synchronization controller 24, and a computer 25. Two synchronization controllers 24 are simultaneously connected to an exposure control box 26. A beam limiter and a butterfly filter are installed at the X-ray exit tip of the X-ray tube 21. The X-ray axis of the X-ray tube 21 is perpendicularly centered relative to the detection surface of the flat panel detector 22 and passes through the isocenter point of the rotating frame 10. Each flat panel detector 22 is connected to the computer 25 via an image acquisition workstation 27. The computer 25 is equipped with an image-guided positioning software system.

[0037] The X-ray tube 21 is used to generate X-rays; the high-voltage generator is used to control and drive the X-ray tube to generate X-rays; the beam limiter is used to limit the size of the X-ray field; the butterfly filter is used to filter out low-energy X-rays to reduce their impact on image quality; the synchronous controller performs high real-time synchronous control of the X-ray generation by the X-ray tube exposure and the image acquisition by the flat panel detector and the acquisition of the gantry angle, thereby ensuring image quality (i.e., the flat panel detector acquires images while the X-ray tube is being exposed, the time being tens to hundreds of milliseconds; the gantry angle is acquired at the midpoint of the exposure time; the exposure time can be set by the user in the software interface based on experience, and the exposure time and other values ​​are related to image quality, and the software will also provide default empirical values); the exposure control box is used for the control of moving parts and the start or stop of X-ray exposure; the image-guided positioning software system is used for the workflow control, image display and reconstruction registration algorithm execution of the cone-beam CT system 20. In this utility model, the image-guided positioning software system can perform three-dimensional imaging and reconstruction registration of the patient in the treatment position to calculate the positioning deviation. After correcting the positioning deviation using the treatment bed, the positioning can be confirmed again by the imaging results of cone-beam CT or orthogonal DR.

[0038] The flat panel detector 22 is used to detect X-rays to generate a projected image.

[0039] The 6D treatment bed 40 is used to accurately position the imaging object (such as the patient) and to correct the positioning deviation according to the cone-beam CT system, thereby achieving precise positioning of the imaging object.

[0040] In this embodiment, as shown in FIG5, the six-dimensional treatment bed 40 includes a control cabinet 41, a six-axis robotic arm 42 electrically connected to the control cabinet, and a treatment bed board 43 connected to the end of the six-axis robotic arm 42. The treatment bed board 43 is made of carbon fiber.

[0041] Based on the proton-helium ion therapy device described above, the placement method of the proton-helium ion therapy device includes the following steps:

[0042] Step S0: Provide the proton-helium ion therapy device described above;

[0043] Step S1: Initially position the imaging object according to the crosshairs on the surface of the imaging object, so that the imaging object is in the initial position; according to the positioning deviation of the initial position relative to the isocenter point, use the six-dimensional treatment bed to initially move the imaging object to the isocenter point.

[0044] Step S2: Move the rotating gantry to the initial angle of the CT imaging mode, thereby moving the components of the cone-beam CT system (such as flat panel detectors, beam limiters, disc filters, etc.) to the correct initial position of the CT imaging mode along with the rotating gantry.

[0045] The cone-beam CT system 20 includes two sets of orthogonal CT imaging modules. Each CT imaging module includes an X-ray tube 21 fixedly mounted on a rotating gantry 10 and a flat panel detector 22 fixedly mounted on one side of the treatment head. The flat panel detectors 22 of the two CT imaging modules are mechanically mounted on both sides of the treatment head and the beam delivery system 30. Thus, the cone-beam CT system 20 can perform cone-beam CT imaging in conjunction with the rotation of the rotating gantry 10.

[0046] As shown in Figures 1 and 4, each X-ray tube 21 is sequentially connected to a high-voltage generator 23, a synchronization controller 24, and a computer 25. Two synchronization controllers 24 are simultaneously connected to the exposure control box 26. A beam limiter and a butterfly filter are installed at the X-ray exit end of the X-ray tube 21. The X-ray axis of the X-ray tube 21 is perpendicularly centered relative to the detection surface of the flat panel detector 22 and passes through the isocenter point of the rotating gantry 10. The flat panel detector is mechanically mounted on one side of the treatment head and beam delivery system 30. Thus, the flat panel detector 22 is used to detect X-rays to generate a projection image, the X-ray tube 21 is used to generate X-rays, the high-voltage generator 23 is used to control and drive the X-ray tube to generate X-rays, the beam limiter is used to limit the X-ray field size, and the butterfly filter is used to filter out low-energy X-rays to reduce their impact on image quality.

[0047] Step S3: Perform the corresponding CT imaging according to the specified CT imaging mode.

[0048] The CT imaging modes include cone-beam CT mode and orthogonal DR mode. When the specified CT imaging mode is cone-beam CT mode, one set of CT imaging components of cone-beam CT system 20 is used to acquire 360-degree multi-frame sequence images. When the specified CT imaging mode is orthogonal DR mode, two sets of mutually orthogonal CT imaging components of cone-beam CT system 20 are used to perform 45-degree or 315-degree orthogonal DR imaging.

[0049] In step S3, orthogonal DR or cone-beam CT can be selected for localization based on the clinical situation. Cone-beam CT provides high-precision localization of the tumor target area, offering higher accuracy and generating clearer 3D images, facilitating oncologists' assessment of the localization results. Orthogonal DR, on the other hand, offers advantages such as faster localization speed and lower requirements for the treatment bed angle, compensating for scenarios where cone-beam CT imaging is not possible due to treatment bed misalignment. In this embodiment, cone-beam CT mode is used when the long axis of the treatment bed is parallel to the rotation axis of the rotating gantry (i.e., the angle is less than the angle threshold); otherwise, if the long axis of the treatment bed is not parallel to the rotation axis of the rotating gantry, exceeding the angle threshold, orthogonal DR mode is used. The angle threshold can be, for example, 3 degrees.

[0050] Step S4: Reconstruct and register based on CT imaging results to obtain the positioning deviation;

[0051] Both reconstruction and registration are implemented using existing mature software. In this embodiment, the three-dimensional reconstruction of cone-beam CT imaging results is performed using the general FDK reconstruction algorithm, and the positioning deviation is calculated using a general mutual information-based three-dimensional registration algorithm.

[0052] The positioning deviation includes the positioning deviation of the treatment bed in six dimensions: X-axis, Y-axis, Z-axis, Rx-axis, Ry-axis, and Rz-axis. By adjusting the value of the positioning deviation, the patient can be accurately positioned at the isocenter of the treatment.

[0053] Step S5: Correct the positioning using the treatment bed based on the positioning deviation.

[0054] Step S6: Perform CT imaging again to verify the positioning deviation results. If the positioning deviation meets the clinical requirements, the positioning ends; otherwise, return to step S2 until the positioning deviation meets the clinical requirements.

[0055] The clinical requirement is that the deviation in the six dimensions of X-axis, Y-axis, Z-axis, Rx-axis, Ry-axis, and Rz-axis should be less than 1 mm or 1 degree.

[0056] Step S7: According to the treatment plan, switch the injector to a proton source or a helium ion source;

[0057] Step S8: Perform scanning irradiation of multiple energy layers sequentially according to the treatment angle specified in the treatment plan until all energy layer scans at that treatment angle are completed;

[0058] During scanning irradiation of the energy layer, the rotating gantry 10 is rotated to the treatment angle specified in the treatment plan, and the range shifter 35 is moved to the position required by the treatment plan via the treatment head telescopic mechanism 36 to reduce the influence of beam spread. The range shifter 35 is connected to the treatment head support via the treatment head telescopic mechanism 35, allowing for adjustable distance between the scanning magnet and the range shifter 35, thus reducing the influence of beam spread.

[0059] In addition, the accelerator energy is adjusted to switch to the next energy level for irradiation.

[0060] Step S9: Rotate to the next specified treatment angle according to the treatment plan, return to step S8, and continue until scanning and irradiation of all angles are completed. At this point, the scanning and irradiation of the imaging object is complete.

[0061] This invention employs cone-beam CT positioning technology based on a rotating gantry. During the positioning process, multi-angle cone-beam CT imaging can be performed via a 360-degree rotating gantry. Cone-beam CT positioning offers advantages such as three-dimensional imaging, high-quality soft tissue imaging, and high positioning accuracy. Furthermore, the rotating gantry-based cone-beam CT allows for imaging and positioning at the treatment position, reducing additional deviations caused by non-treatment position positioning techniques and simplifying the treatment process. This results in more precise and effective positioning for proton and helium ion therapy. The integrated scanning magnet design effectively shortens the source axis distance, making the treatment head more compact and facilitating the installation of the cone-beam CT system.

[0062] Furthermore, this invention allows for the selection of orthogonal DR or cone-beam CT for localization based on clinical conditions. Cone-beam CT provides high-precision localization of the tumor target area, offering higher positioning accuracy and generating clearer three-dimensional images, facilitating oncologists' assessment of the localization results. Orthogonal DR, on the other hand, offers advantages such as faster localization speed and lower requirements for the treatment bed angle, thus compensating for localization scenarios where cone-beam CT imaging cannot be performed due to treatment bed misalignment.

[0063] This invention selects protons and helium ions for radiotherapy based on clinical needs, and can perform multi-angle intensity-modulated therapy through a 360-degree rotating gantry. It solves the problems of positioning errors in particle therapy and the immunity of hypoxic tumors to proton therapy, and can meet the needs of different cancer treatment centers and patients for particle therapy with better performance.

[0064] The above description is merely a preferred embodiment of this utility model and is not intended to limit the scope of this utility model. Various variations can be made to the above embodiments of this utility model. That is, all simple and equivalent changes and modifications made based on the claims and description of this utility model application fall within the protection scope of the claims of this utility model patent. Any aspects of this utility model not described in detail are conventional technical content.

Claims

1. A proton-helium ion therapy device, characterized in that, The device includes an injector, an accelerator, a rotating gantry, a treatment head and beam delivery system, and a six-dimensional treatment bed, arranged sequentially along the beam transport direction. A cone-beam CT system is also fixedly mounted on the rotating gantry. The injector includes a switchable hydrogen ion source and a helium ion source. The treatment head and beam delivery system includes an integrated scanning magnet, a position ionization chamber, a dose ionization chamber, a ridge filter, and a range shifter, all mounted on the treatment head support and arranged sequentially along the beam transport direction. The integrated scanning magnet is also used for beam deflection in the transverse XY directions.

2. The proton-helium ion therapy device according to claim 1, characterized in that, The integrated scanning magnet has a vacuum box and a vacuum window, and is connected to a scanning power supply to drive the magnetic field of the scanning magnet.

3. The proton-helium ion therapy device according to claim 1, characterized in that, The position ionization chamber is a multi-wire ionization chamber; the dose ionization chamber includes a main dose ionization chamber and a secondary dose ionization chamber, the secondary dose ionization chamber providing redundant measurement of the irradiation dose; the ridge filter is used to extend the Bragg peak width of the beam.

4. The proton-helium ion therapy device according to claim 1, characterized in that, The range shifter is connected to the treatment head support via a treatment head telescopic mechanism to make the distance from the scanning magnet to the range shifter adjustable.

5. The proton-helium ion therapy device according to claim 1, characterized in that, The cone-beam CT system is switchable between cone-beam CT imaging mode and orthogonal DR imaging mode; the cone-beam CT system includes two sets of mutually orthogonal CT imaging components, each set of CT imaging components including an X-ray tube fixedly mounted on a rotating gantry and a flat panel detector fixedly mounted on one side of the treatment head.

6. The proton-helium ion therapy device according to claim 5, characterized in that, Each X-ray tube is sequentially connected to a high-voltage generator, a synchronization controller, and a computer. Two synchronization controllers are simultaneously connected to the exposure control box, and a beam limiter and a butterfly filter are installed at the front end of the X-ray tube's exit. The X-ray central axis of the tube is perpendicularly centered relative to the detection surface of the flat panel detector and passes through the isocenter point of the rotating frame.

7. The proton-helium ion therapy device according to claim 1, characterized in that, The six-dimensional treatment bed includes a control cabinet, a six-axis robotic arm electrically connected to the control cabinet, and a treatment bed board connected to the end of the six-axis robotic arm. The treatment bed board is made of carbon fiber.