Screw reagent bottle for in-vitro diagnostic reagent

Abstract

The utility model relates to a screw reagent bottle for an in-vitro diagnostic reagent. The screw reagent bottle comprises a bottle body and a bottle cap, the bottle body is made of glass, the bottle opening is a threaded opening, and the bottle bottom is provided with a micro-groove. The bottle cap is made of plastic and is provided with a first end face, a second end face and a third end face, anti-skid stripes are regularly arranged on the outer side of the first end face, threads are arranged on the inner side of the first end face, the first end face and the second end face are in a concentric circle shape, the second end face is an annular protrusion, the third end face is in a plane shape, and a sealing ring is arranged between the first end face and the second end face. The in-vitro diagnostic reagent storage and transportation device is simple in structure, improves sealing performance by optimizing structural design, is suitable for storage and transportation of in-vitro diagnostic reagents, and has the adaptation capacity of automatic equipment and the operation stability of reagent bottles.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical packaging technology, specifically to a screw-top reagent bottle for in vitro diagnostic reagents. Background Technology

[0002] In the field of in vitro diagnostic (IVD) reagents, reagent bottles serve as the primary storage containers for liquid reagents. The sealing performance, stability, and ease of use of these bottles directly impact the preservation effectiveness and testing accuracy of the reagents. Currently, reagent bottles on the market mainly employ two structures: ordinary threaded bottles and aluminum-capped vials. The former relies solely on thread engagement for sealing, and long-term storage can lead to leakage due to material deformation or temperature changes, affecting reagent concentration. The latter requires a special tool to open, and once opened, it is difficult to reseal, affecting reagent efficacy. Furthermore, existing reagent bottles still have shortcomings in the following aspects: poor anti-slip properties: laboratory personnel wearing gloves are prone to slipping, affecting opening efficiency; insufficient standardization: different manufacturers use inconsistent thread specifications, affecting the compatibility of automated instruments; missing or deteriorated sealing rings: some products lack elastic sealing rings or use low-quality rubber, which hardens and fails after long-term use. Therefore, there is an urgent need for a reagent bottle that combines high sealing performance, ease of operation, and structural stability to meet the stringent requirements of in vitro diagnostic reagents for long-term storage and accurate retrieval. Utility Model Content

[0003] This utility model relates to the field of pharmaceutical packaging technology, specifically to a screw-top reagent bottle for in vitro diagnostic reagents, comprising a bottle body and a bottle cap; the bottle body is made of glass, the bottle mouth is threaded, and the bottom of the bottle has a micro-groove; the bottle cap is made of plastic, and the bottle cap has a first end face, a second end face, and a third end face, the outer side of the first end face is provided with regularly arranged anti-slip stripes, the inner side of the first end face is threaded, the first end face and the second end face are concentric circles, the second end face is an annular protrusion, the third end face is flat, and a sealing ring is between the first end face and the second end face.

[0004] As a further improvement to this utility model, the bottle body is made of high borosilicate glass.

[0005] As a further improvement of this utility model, the bottle body is cylindrical, with a height of less than or equal to 38mm and a bottom diameter of less than or equal to 21mm.

[0006] As a further improvement of this utility model, the micro-groove at the bottom of the bottle is an annular groove with a diameter of less than or equal to 5 mm.

[0007] As a further improvement of this utility model, the bottle mouth is provided with an external thread, the height of which is less than or equal to 12mm, the thickness of which is less than or equal to 2mm, and the inner diameter of which is less than or equal to 12mm.

[0008] As a further improvement to this utility model, the bottle cap is made of polypropylene plastic.

[0009] As a further improvement of this utility model, the bottle cap is provided with an internal thread that fits perfectly with the external thread of the bottle mouth.

[0010] As a further improvement to this utility model, the bottle cap is green, orange, yellow, brown, or white.

[0011] As a further improvement to this utility model, the inner sealing ring of the bottle cap is made of transparent silicone.

[0012] As a further improvement of this utility model, the external thread of the bottle body and the internal thread of the bottle cap, the annular protrusion of the bottle mouth and the sealing ring of the bottle cap form a triple seal.

[0013] The reagent bottle provided by this utility model has the following advantages:

[0014] 1. The bottle body is made of high borosilicate glass, which has strong impact resistance and is not easily broken. This gives the bottle body good thermal stability and chemical corrosion resistance, thus ensuring that the reagents can be stored for a long time without deterioration.

[0015] 2. The bottle cap is made of plastic, which is not only lightweight and easy to operate, but also not easy to oxidize, discolor, corrode, or rust.

[0016] 3. The screw-on interface of the bottle cap has a rubber ring inside, which ensures a tight fit between the bottle body and the cap while preventing leakage.

[0017] 4. Tighten the bottle cap with appropriate torque to avoid over-tightening and damaging the cap.

[0018] 5. Precise control of the bottle cap thread parameters ensures an effective fit between the bottle cap and the bottle body.

[0019] 6. The bottle height and diameter are adapted to the reagent compartment of fully automated testing equipment. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the bottle structure of this utility model;

[0021] Figure 2 This is a schematic diagram of the bottle cap structure of this utility model;

[0022] Figure 3 This is a schematic diagram of the inner side of the bottle cap of this utility model;

[0023] In the diagram: 1. Bottle body; 2. Bottle cap; 3. External thread; 4. Internal thread; 5. First end face; 6. Second end face; 7. Third end face; 8. Sealing ring; 9. Microgroove. Detailed Implementation

[0024] The technical solution of this utility model will now be clearly and completely described with reference to the accompanying drawings and embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0025] Combination Figure 1 As shown in the embodiment of this utility model, a reagent bottle is provided, including a bottle body 1 and a bottle cap 2;

[0026] Bottle 1 is made of high borosilicate glass, which has good chemical stability and heat resistance, and is suitable for storing in vitro diagnostic reagents;

[0027] The external thread 3 of the bottle neck adopts a standard thread design, which facilitates a tight fit with the bottle cap;

[0028] The height of bottle 1 is 38mm, the inner diameter of the bottle mouth is 12mm, the outer diameter of the bottle mouth is 16mm, the bottom diameter is 21mm, and the volume of the reagent bottle is 1-7mL.

[0029] The bottom of the bottle features a micro-groove 9 to enhance the structural stability of the reagent bottle and prevent it from tipping over during transportation or handling;

[0030] Bottle cap 2 is made of medical-grade polypropylene plastic to ensure chemical inertness and prevent reaction with reagents;

[0031] The bottle cap 2 is composed of a first end face 5, a second end face 6, and a third end face 7;

[0032] The outer side of the first end face 5 is provided with anti-slip stripes arranged in a regular pattern to facilitate tightening or opening the bottle cap;

[0033] The inner side of the first end face 5 is provided with an internal thread 4 that matches the external thread 3 of the bottle mouth, to ensure that the bottle cap and the bottle body are tightly connected.

[0034] The second end face 6 is an annular protrusion, which is concentric with the first end face 5. It cooperates with the bottle mouth to form a double lock to prevent liquid leakage.

[0035] The third end face 7 is a flat structure, which facilitates labeling or writing / printing of markings.

[0036] A silicone sealing ring 8 is embedded between the first end face 5 and the second end face 6 to ensure the airtightness and liquid tightness between the cap and the bottle body, and to prevent reagent leakage or external contamination.

[0037] The outer diameter d of bottle cap 2 is less than or equal to 22mm, the thickness is less than or equal to 2mm, and the weight is less than or equal to 2g;

[0038] The inner diameter of the thread pitch circle D1 of bottle cap 2 is 16-17mm, the pitch P is 3-4mm, and the surface roughness Ra is less than or equal to 0.8μm.

[0039] The screw-tightening torque T between the bottle cap 2 and the bottle body 1 is 3 N·cm-5 N·cm.

[0040] The bottle body 1 is preferably made of grade 3.3 high borosilicate glass tubing, which has excellent thermal stability and chemical corrosion resistance, meeting the requirements for long-term reagent storage. The cap 2 is injection molded from polypropylene (PP) material, featuring lightweight convenience and resistance to oxidation and discoloration. A sealing ring 8 is embedded between the internal thread 4 and the third end face 7, providing a seal while reducing friction, making it easy to open the cap 2. The cap 2 has a small overall size, making it easy for users to hold and operate. The thread parameters of the cap 2 have been precisely calculated to achieve the optimal value, ensuring an effective connection between the cap 2 and the bottle body 1 while avoiding overtightening that could damage the cap 2. The color of the cap 2 conforms to ergonomic principles, enhancing the user experience. The sealing ring 8 between the cap 2 and the bottle body 1 increases the sealing performance, ensuring that the reagent does not leak. The height and diameter of the bottle body 1 are moderate, making it easy for users to take out the reagent. The tightening torque of the cap 2 is appropriate, avoiding overtightening that could damage the cap 2.

[0041] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A screw-top reagent bottle for in vitro diagnostic reagents, characterized in that, It includes a bottle body and a bottle cap; the bottle body is made of glass with a threaded opening and a micro-groove at the bottom; the bottle cap is made of plastic and has a first end face, a second end face, and a third end face. The outer side of the first end face has regularly arranged anti-slip stripes, the inner side of the first end face is threaded, the first end face and the second end face are concentric circles, the second end face is an annular protrusion, the third end face is flat, and there is a sealing ring between the first end face and the second end face.

2. The screw-cap reagent bottle for in vitro diagnostic reagents according to claim 1, characterized in that, The bottle body is made of high borosilicate glass.

3. The screw-cap reagent bottle for in vitro diagnostic reagents according to claim 1, characterized in that, The bottle body also includes an external thread located at the bottle mouth, with a thread height ranging from 10 to 12 mm and an inner diameter of the bottle mouth ranging from 11 to 12 mm.

4. The screw-cap reagent bottle for in vitro diagnostic reagents according to claim 1, characterized in that, The bottom of the bottle has a microgroove, which is an annular groove. The depth of the microgroove ranges from 0.1 to 0.2 mm, and the diameter ranges from 3 to 5 mm.

5. The screw-cap reagent bottle for in vitro diagnostic reagents according to claim 1, characterized in that, The bottle body is cylindrical, with a bottom diameter ranging from 20 to 23 mm, a thickness ranging from 2 to 4 mm, and a total height ranging from 36 to 38 mm.

6. The screw-cap reagent bottle for in vitro diagnostic reagents according to claim 1, characterized in that, The bottle cap is made of polypropylene plastic.

7. The screw-cap reagent bottle for in vitro diagnostic reagents according to claim 1, characterized in that, The bottle cap has internal threads.

8. The screw-top reagent bottle for in vitro diagnostic reagents according to claim 1, characterized in that, The bottle cap has an annular protrusion inside.

9. The screw-cap reagent bottle for in vitro diagnostic reagents according to claim 1, characterized in that, The bottle cap has a sealing ring between its internal thread and the annular protrusion, and the sealing ring is made of silicone.

10. The screw-cap reagent bottle for in vitro diagnostic reagents according to claim 1, characterized in that, The bottle cap has regularly arranged anti-slip stripes.

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