Digestive tract endoscopic biopsy pathological sample fixing box
By designing a fixation box for pathological samples from endoscopic biopsies of the digestive tract, the problems of unstable specimen fixation and insufficient information management were solved, achieving stable specimen fixation and information management, simplifying the operation process, and improving diagnostic efficiency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- GUANGZHOU KINGMED CENTER FOR CLINICAL LABORATORY CO LTD
- Filing Date
- 2025-05-30
- Publication Date
- 2026-05-05
AI Technical Summary
Existing specimen embedding and fixation cassettes are not effective at securing small endoscopic biopsy specimens, which can easily lead to specimens moving around or leaking out. Furthermore, the lack of information management increases the number of operational steps and the risk of confusion.
A fixation box for pathological samples from endoscopic biopsy of the digestive tract was designed, comprising an embedding box base and a top cover. It is equipped with a filter paper fixation area, a pathology number coding area, a specimen identification area, and a QR code pasting area. The top cover is connected by a flexible bending strip and is equipped with a locking structure and through holes to ensure specimen fixation and information management.
It effectively fixes small specimens, preventing loss and contamination, simplifies the operation process, and improves work efficiency and diagnostic accuracy.
Smart Images

Figure CN224198240U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the field of medical supplies, specifically relating to a fixation box for pathological samples obtained from digestive tract endoscopic biopsy. Background Technology
[0002] An endoscope embedding cassette is a device used to fix and preserve endoscopic tissue specimens in pathological studies. After an endoscopy, doctors may collect a small tissue sample for pathological examination. These tissue specimens need to be embedded in a fixative, then sectioned and stained for histological observation and disease diagnosis. It provides researchers with an efficient, convenient, and standardized way to accurately preserve, process, and analyze biological endoscopic tissues.
[0003] Existing specimen embedding and fixation cassettes are generally of a uniform size, suitable for tissues ranging in size from 0.1*0.1*0.1 mm³ to 2*1.5*2 mm³. For larger samples, fixation is relatively good, but for smaller endoscopic biopsy specimens, they often tend to move around within the cassette, and occasionally, after formalin fixation, they shrink and leak out through gaps. Sometimes, for small endoscopic biopsy specimens, eosin staining is required, followed by wrapping with filter paper before placing them in the embedding and fixation cassette, adding to the cumbersome process. Summary of the Invention
[0004] The purpose of this invention is to provide a digestive tract endoscopic biopsy pathological sample fixation box that prevents the loss of the specimen inside the box and the contamination of the specimen from the outside.
[0005] The technical solution is as follows:
[0006] A gastrointestinal endoscopic biopsy pathology sample fixation box includes an embedding box base and an embedding box cover. The embedding box cover is placed on the embedding box base. A pathology number coding area is opened on the upper front side of the embedding box base. A groove is opened in the middle of the upper surface of the embedding box base. At least part of the space in the groove forms a specimen fixation area. Filter paper is provided on the bottom wall and circumferential side wall of the specimen fixation area. A specimen identification area is opened on the upper surface of the embedding box base behind the specimen fixation area. A QR code pasting area is opened on the upper surface of the embedding box base to the left of the specimen identification area.
[0007] In one embodiment, a flexible bending strip is fixedly connected above the embedding cassette base between the specimen fixation area and the specimen identification area. The end of the bending strip is fixedly connected to the top cover of the embedding cassette, and an easy-tear opening is provided on one side of the bending strip.
[0008] In one embodiment, the top of the embedding box and the bottom of the specimen fixation area are provided with several through holes for liquid permeation.
[0009] In one embodiment, a lever is fixedly connected to one end of the front side of the embedding box cover.
[0010] In one embodiment, a cover plate is fixedly connected to the center of the bottom surface of the embedding box, and filter paper is detachably installed on the circumferential sidewalls and bottom wall of the groove, and the groove as a whole forms the specimen fixation area.
[0011] In one embodiment, the filter paper is a medical-grade qualitative filter paper with a pore size of one to five micrometers and a thickness of 0.2 millimeters.
[0012] In one embodiment, two sets of locking holes are provided through the front side of the top cover of the embedding box, and two connecting posts are fixedly connected to the front side of the specimen fixation area on the top of the embedding box base. The positions of the two connecting posts correspond to the positions of the locking holes, and locking caps are fixedly connected to the top of each of the two connecting posts.
[0013] In one embodiment, the locking cap is mushroom-shaped, narrower at the top and wider at the bottom, and the bottom of the locking cap is chamfered. The locking cap and the connecting post are an integral injection-molded structure.
[0014] In one embodiment, support protrusions are fixedly connected to the four corners of the bottom surface of the embedding box base.
[0015] In one embodiment, the specimen identification area and the QR code pasting area are located outside the covering area of the embedding box base.
[0016] The technical solution provided by this utility model has the following advantages and effects:
[0017] 1. This utility model provides a filter paper in the specimen fixation area. The filter paper can wrap and fix small endoscopic biopsy specimens, reducing the chance of the specimen moving around in the box or flowing out from the gaps, and effectively preventing specimen loss.
[0018] 2. This utility model, by setting up a pathology number coding area, a specimen identification area, and a QR code pasting area, facilitates medical staff in numbering, identifying, and managing specimens with information, thereby improving work efficiency and reducing the possibility of specimen confusion.
[0019] 3. This utility model connects the embedding cassette cover to the embedding cassette base via a flexible bending strip, and the bending strip has an easy-tear opening for convenient opening and closing of the embedding cassette. The lever and locking hole of the embedding cassette cover cooperate with the connecting post and locking cap of the embedding cassette base for easy operation, and the design of the locking cap makes it easier to fasten and open. Attached Figure Description
[0020] Figure 1 This is a schematic diagram of the structure of an embodiment of the present utility model;
[0021] Figure 2 This is a structural schematic diagram from another perspective of an embodiment of the present utility model;
[0022] Figure 3 This is a structural schematic diagram from another perspective of an embodiment of the present utility model;
[0023] Figure 4 This is a schematic diagram of the structure of the present invention with the top cover of the embedding box removed;
[0024] Figure 5 This is a schematic diagram of the embedding box cover structure in an embodiment of the present utility model;
[0025] Figure 6 This is a schematic diagram of the connecting post and locking cap in an embodiment of the present utility model;
[0026] Figure 7 for Figure 2 Enlarged view of a portion of point A in the middle.
[0027] Explanation of reference numerals in the attached figures:
[0028] 1. Embedding cassette base; 2. Pathology number coding area; 3. Specimen identification area; 4. QR code pasting area; 5. Specimen fixation area; 6. Bending strip; 7. Embedding cassette top cover; 8. Easy-tear opening; 10. Locking hole; 11. Paddle; 12. Connecting post; 13. Locking cap; 15. Filter paper; 16. Support protrusion. Detailed Implementation
[0029] To facilitate understanding of this utility model, the specific embodiments of this utility model will be described in more detail below with reference to the accompanying drawings.
[0030] Unless otherwise specified or defined, the terms "first," "second," etc., used in this document are for distinguishing names only and do not represent a specific number or order.
[0031] Unless otherwise stated or defined, the term “and / or” as used herein includes any and all combinations of one or more of the associated listed items.
[0032] It should be noted that in this article, "fixed to" or "connected to" can mean directly fixed to or connected to a component, or indirectly fixed to or connected to a component.
[0033] like Figures 1-7The digestive tract endoscopic biopsy pathology sample fixation box shown includes an embedding box base 1. A pathology number coding area 2 is located on the upper front side of the embedding box base 1. This area facilitates accurate recording and identification of the unique number of each pathology sample by medical staff, avoiding confusion and ensuring the accuracy of pathological diagnosis. A groove is located in the center of the upper surface of the embedding box base 1. Filter paper is installed on the four sides and bottom wall of the groove, forming a specimen fixation area 5. A specimen identification area 3 is located above the embedding box base 1, behind the specimen fixation area 5. This area provides space to record relevant patient sampling information, such as sampling site and time, helping pathologists to fully understand the specimen background and improve diagnostic efficiency. A QR code pasting area 4 is located on the left side of the specimen identification area 3 on the upper surface of the embedding box base 1. The design of the QR code pasting area 4 allows for quick access to detailed specimen information, such as patient information, sampling time, and sampling site, by scanning the QR code, achieving electronic management of specimen information and improving work efficiency. It should be noted that a specimen fixation area 5 can also be formed in part of the space within the groove. For example, a sample placement frame can be fixed in the groove, and filter paper can be adhered to the inner wall of the sample placement frame, thus forming the specimen fixation area 5. Moreover, the number and shape of the sample placement frames are not limited.
[0034] Please refer to Figure 4 As shown, a flexible bending strip 6 is fixedly connected above the embedding cassette base 1 between the specimen fixation area 5 and the specimen identification area 3. The end of the bending strip 6 is fixedly connected to the embedding cassette cover 7. The bending strip 6 allows the embedding cassette cover 7 to be flexibly flipped for easy operation, while maintaining the connection between the cover and the base to prevent loss. The flexible bending strip 6 is an existing product and can be purchased from the market; therefore, it will not be described in detail here.
[0035] Preferably, when the embedding box cover 7 is placed on the embedding box base 1, the specimen identification area 3 and the QR code pasting area 4 are both outside the covering area of the embedding box cover 7, which makes it convenient for operators to view.
[0036] Please refer to Figure 7 As shown, several through holes for liquid permeation are provided on the top of the embedding box cover 7 and the bottom of the specimen fixation area 5. An easy-tear opening 8 is provided on one side of the bending strip 6, which makes it easy to tear off the embedding box cover 7 for subsequent paraffin embedding operations.
[0037] Please refer to Figure 5 As shown, two sets of locking holes 10 are provided through the front side of the upper cover 7 of the embedding box. A lever 11 is fixedly connected to the left front end of the upper cover 7 of the embedding box. The embedding box is sealed through the locking structure to prevent specimen leakage and external contamination. The lever 11 is designed for easy operation.
[0038] Please refer to Figure 6As shown, two connecting posts 12 are fixedly connected above the specimen fixation area 5 on the upper part of the embedding box base 1. The positions of the two connecting posts 12 correspond to the positions of the locking holes 10. Locking caps 13 are fixedly connected above the two connecting posts 12.
[0039] Please refer to Figure 3 As shown, support protrusions 16 are fixedly connected at the four corners of the bottom surface of the embedding box base 1. The support protrusions 16 can keep the embedding box stable when placed, and at the same time, they can allow the fixative to enter the specimen fixation area 5 from the bottom surface of the embedding box base 1, thereby improving the fixation effect of the specimen.
[0040] Please refer to Figure 4 As shown, filter paper 15 is medical-grade qualitative filter paper. The pore size of filter paper 15 is one to five micrometers, and the thickness is 0.2 millimeters. Filter paper 15 is made of medical-grade qualitative filter paper, which has good liquid absorption and air permeability. The moderate pore size (one to five micrometers) can ensure the penetration of fixative and effectively prevent the loss of specimen. The moderate thickness (0.2 millimeters) can ensure strength without being too thick and heavy.
[0041] Please refer to Figure 6 As shown, the locking cap 13 is mushroom-shaped with a narrow top and a wide bottom, and the bottom of the locking cap 13 is chamfered. The locking cap 13 and the connecting post 12 are integral injection molded structures. The mushroom-shaped design and bottom chamfer of the locking cap 13 make it easier to fasten and unfasten.
[0042] Working principle: After obtaining the pathological sample from the digestive tract endoscopic biopsy, medical staff first fill in the corresponding pathological number in the pathological number coding area 2 of the embedding cassette base 1, affix the QR code containing the specimen information in the QR code pasting area 4, and record the relevant patient sampling information in the specimen identification area 3. The collected pathological sample is carefully placed into the filter paper 15. Then, the embedding cassette cover 7 is rotated downwards using the lever 11, causing it to flip along the flexible bending strip 6, covering the specimen fixation area 5. At this time, the locking hole 10 on the embedding cassette cover 7 is aligned with the connecting post 12 on the embedding cassette base 1, and the locking cap 13 is pressed into the locking hole 10. Because the locking cap 13 is narrower at the top... The wide, mushroom-shaped box with a chamfered bottom allows it to be easily snapped into the locking hole 10, sealing the embedding box and preventing specimen leakage and external contamination. The embedding box is then placed in a fixative (such as formalin). The fixative passes through the through-holes in the top cover 7 and the bottom of the specimen fixation area 5, ensuring full contact with the specimen and fixing it. During the penetration process, the fixative acts evenly on all parts of the specimen, ensuring effective fixation. When the specimen needs to be removed for further processing, the lever 11 is manually moved to disengage the locking cap 13 from the locking hole 10. The top cover 7 of the embedding box is then opened, and the filter paper 15 containing the specimen is removed for subsequent pathological examinations such as sectioning and staining.
[0043] The above embodiments are not an exhaustive list based on the present invention, and there may be other embodiments not listed. Any substitutions and improvements made without departing from the concept of the present invention are within the protection scope of the present invention.
Claims
1. A fixation box for pathological samples from endoscopic biopsy of the digestive tract, characterized in that, The device includes an embedding cassette base and an embedding cassette cover. The embedding cassette cover is placed on the embedding cassette base. A pathology number coding area is provided on the upper front side of the embedding cassette base. A groove is provided in the middle of the upper surface of the embedding cassette base. At least part of the space in the groove forms a specimen fixation area. Filter paper is provided on the bottom wall and circumferential side wall of the specimen fixation area. A specimen identification area is provided on the upper surface of the embedding cassette base behind the specimen fixation area. A QR code pasting area is provided on the left side of the specimen identification area on the upper surface of the embedding cassette base.
2. The endoscopic biopsy pathology sample fixation box as described in claim 1, characterized in that: A flexible bending strip is fixedly connected above the base of the embedding box between the specimen fixation area and the specimen identification area. The end of the bending strip is fixedly connected to the top cover of the embedding box, and an easy-tear opening is provided on one side of the bending strip.
3. The endoscopic biopsy pathology sample fixation box as described in claim 2, characterized in that: The top of the embedding box and the bottom of the specimen fixation area are both provided with several through holes for liquid permeation.
4. The endoscopic biopsy pathology sample fixation box as described in claim 2, characterized in that: A lever is fixedly connected to one end of the front side of the top cover of the embedding box.
5. The endoscopic biopsy pathology sample fixation box as described in claim 1, characterized in that: Filter paper is detachably installed on the circumferential sidewalls and bottom wall of the groove, and the groove as a whole forms the specimen fixing area.
6. The endoscopic biopsy pathology sample fixation box as described in claim 5, characterized in that: The filter paper is a medical-grade qualitative filter paper with a pore size of one to five micrometers and a thickness of 0.2 millimeters.
7. The digestive tract endoscopic biopsy pathology sample fixation box as described in any one of claims 1-5, characterized in that: Two sets of locking holes are provided through the front side of the top cover of the embedding box. Two connecting posts are fixedly connected to the front side of the specimen fixation area on the top of the embedding box base. The positions of the two connecting posts correspond to the positions of the locking holes. Locking caps are fixedly connected to the top of each of the two connecting posts.
8. The endoscopic biopsy pathology sample fixation box as described in claim 7, characterized in that: The locking cap is mushroom-shaped, narrower at the top and wider at the bottom, and has a chamfer at the bottom. The locking cap and the connecting column are an integral injection-molded structure.
9. The digestive tract endoscopic biopsy pathological sample fixation box as described in any one of claims 1 to 5, characterized in that: Supporting protrusions are fixedly connected at the four corners of the bottom surface of the embedding box base.
10. The digestive tract endoscopic biopsy pathological sample fixation box as described in any one of claims 1 to 5, characterized in that: The specimen identification area and the QR code pasting area are located on the top of the embedding box, outside the covering area of the embedding box base.