Tissue sample storage device
By designing a suitable sample container mounting slot and flexible mounting components, combined with low-temperature freezing components and sterile bags, the problems of tipping and temperature loss during tissue sample transportation were solved, achieving a stable low-temperature environment and maintaining biological characteristics.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- SHANGHAI JUNCELL THERAPEUTICS CO LTD
- Filing Date
- 2025-04-09
- Publication Date
- 2026-05-08
AI Technical Summary
When transporting fresh tissue samples over long distances, existing technologies often require containers holding tissue samples to tip over, necessitating opening the box to adjust its position. This can lead to temperature loss inside the box, affecting the biological characteristics of the tissue samples.
A tissue sample preservation device was designed, including a sample container and a preservation component. The sample container is placed in a first mounting slot with a suitable shape and is kept stable by elastic mounting components and low-temperature freezing components to prevent tipping. The environment is monitored by sterile bags and temperature and humidity sensors to ensure a low-temperature state.
It effectively prevents containers from tipping over, maintains a low-temperature environment, ensures the stability of the biological characteristics of tissue samples, improves transportation efficiency and safety, prevents cross-contamination, and ensures the continuity of data monitoring.
Smart Images

Figure CN224211498U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of medical supplies technology, and more specifically, to a tissue sample preservation device. Background Technology
[0002] Fresh, highly viable tissues are essential materials for numerous medical and research applications. However, there is often a distance between obtaining fresh tissue samples and the site of use for medical or research purposes, frequently necessitating the transportation and transfer of the tissues.
[0003] When the distance between two locations is long, tissues usually need to be transported at low temperatures to ensure that the tissue samples remain fresh and retain their basic biological characteristics during long-distance transport. During transport, tissue samples are usually placed in containers containing tissue preservation solutions, such as culture medium bottles or tissue preservation tanks, wrapped with foam, and then placed in a transport box along with ice packs.
[0004] However, conventional foam packaging is mostly placed inside a box. During transportation, the container holding the tissue sample is prone to tipping over. The box needs to be opened and the container uprighted. During the process of opening and uprighting, the inside of the box comes into contact with the outside space, which can easily lead to heat loss inside the box. This causes the temperature of the tissue sample stored in the container to rise, exceeding the upper limit of the temperature required for low-temperature transportation, which has an adverse effect on the biological characteristics of the tissue sample. Utility Model Content
[0005] The purpose of this invention is to provide a tissue sample preservation device to alleviate the technical problem in the prior art where containers holding tissue samples are prone to tipping over, requiring the box to be opened and the container to be uprighted, which can easily lead to temperature loss inside the box.
[0006] This utility model provides a tissue sample preservation device, including: a sample container and a preservation component; the sample container is used to store tissue samples; the preservation component includes a box, the box is an openable and closable structure with a holding space, and the holding space is provided with a first mounting groove for placing the sample container; wherein, the shape of the first mounting groove is adapted to the shape of the sample container, and the box is provided with a first gap for placing a low-temperature freezing component.
[0007] Furthermore, the storage component also includes a flexible mounting member; the flexible mounting member is disposed in the holding space, and the first mounting groove is disposed on the flexible mounting member; the first gap of the low-temperature freezing component is disposed between the flexible mounting member and the box body.
[0008] Furthermore, there are multiple first mounting slots; the multiple first mounting slots are spaced apart on the elastic mounting member.
[0009] Furthermore, installation gaps are provided between the side wall of the elastic mounting member and the inner side wall of the box, and between the bottom surface of the elastic mounting member and the bottom surface of the box; the installation gaps form the first gap.
[0010] Furthermore, the elastic mounting component is also provided with a second mounting groove; the second mounting groove is located on one side of the first mounting groove and is used to place the temperature measuring component.
[0011] Furthermore, the tissue sample preservation device also includes a sterile bag; the sterile bag is used to fit over the sample container.
[0012] Furthermore, the sterile bag includes an inner bag and an outer bag; the inner bag and the outer bag are sequentially fitted over the sample container from the inside out.
[0013] Furthermore, the tissue sample preservation device also includes a temperature and humidity sensor; the temperature and humidity sensor is disposed in the second mounting slot.
[0014] Furthermore, the elastic mounting component is made of foam material.
[0015] Furthermore, the sample container is a tissue preservation box.
[0016] Beneficial effects:
[0017] When using the tissue sample preservation device provided by this utility model, the tissue sample can be placed in a sample container when it is necessary to transport the tissue sample. The sample container containing the tissue sample is then filled into the first mounting slot. Subsequently, a low-temperature freezing component is placed in the first gap and the box is closed to keep the temperature inside the box low. The shape of the first mounting slot is adapted to the shape of the sample container, so that the sample container can be stably placed in the first mounting slot and is not easy to tip over. This avoids the need to open the box and straighten the container, and keeps the box in a low-temperature refrigeration state, thereby preventing the temperature of the tissue sample stored in the container from rising and keeping the biological characteristics of the tissue sample stable. Attached Figure Description
[0018] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.
[0019] Figure 1 A schematic diagram of the structure of the tissue sample preservation device provided in this embodiment of the utility model;
[0020] Figure 2A schematic diagram showing the positional relationship between the first mounting slot and the second mounting slot within the housing in the tissue sample preservation device provided in this embodiment of the utility model.
[0021] Figure 3 A schematic diagram showing the positional relationship between the housing and the elastic mounting component in the tissue sample preservation device provided in this embodiment of the utility model;
[0022] Figure 4 This is a schematic diagram of the structure of the box in the tissue sample preservation device provided in an embodiment of the present invention;
[0023] Figure 5 A top view of the elastic mounting component in the tissue sample preservation device provided in this embodiment of the utility model;
[0024] Figure 6 A schematic diagram of the split structure of the sample container in the tissue sample preservation device provided in this embodiment of the utility model.
[0025] icon:
[0026] 100 – Sample container; 110 – Box body; 120 – Box lid;
[0027] 200 – Storage component; 210 – Housing; 220 – First mounting slot; 230 – First gap; 240 – Elastic mounting element; 250 – Second mounting slot. Detailed Implementation
[0028] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, and not all embodiments. The components of the embodiments of this utility model described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.
[0029] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.
[0030] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.
[0031] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship commonly used when the product of this utility model is in use. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. In addition, the terms "first," "second," and "third," etc., are only used to distinguish descriptions and should not be construed as indicating or implying relative importance.
[0032] Furthermore, terms such as "horizontal" and "vertical" do not imply that components must be absolutely horizontal or suspended, but rather that they can be slightly tilted. For example, "horizontal" simply means that its direction is more horizontal than "vertical," and does not mean that the structure must be completely horizontal, but can be slightly tilted.
[0033] In the description of this utility model, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.
[0034] The present invention will now be described in further detail with reference to specific embodiments and accompanying drawings.
[0035] like Figures 1 to 6 The tissue sample preservation device provided in this embodiment includes a sample container 100 and a preservation component 200.
[0036] The sample container 100 is used to store tissue samples. The storage component 200 includes a box 210, which is an openable and closable structure with a holding space. The holding space is provided with a first mounting slot 220 for placing the sample container 100.
[0037] Furthermore, the shape of the first mounting groove 220 is adapted to the shape of the sample container 100, and the box 210 is provided with a first gap 230 for setting the low-temperature freezing component.
[0038] Specifically, when transporting tissue samples using the tissue sample preservation device provided in this embodiment, the tissue sample can be placed in the sample container 100, and the sample container 100 containing the tissue sample can be filled into the first mounting slot 220. Then, a low-temperature freezing component is placed in the first gap 230 and the box 210 is closed to keep the temperature inside the box 210 low.
[0039] Since the shape of the first mounting groove 220 is adapted to the shape of the sample container 100, the sample container 100 can be stably placed in the first mounting groove 220 and is not easy to tip over. There is no need to open the box 210 to adjust the placement of the sample container 100, so that the box 210 can be kept in a low temperature refrigeration state. This prevents the temperature of the tissue sample stored in the container from rising due to contact with the outside of the box 210, and keeps the biological characteristics of the tissue sample stable.
[0040] In this embodiment, the storage component 200 further includes a resilient mounting member 240. The resilient mounting member 240 is disposed in the holding space, and a first mounting groove 220 is disposed on the resilient mounting member 240. A first gap 230 of the cryogenic freezing component is disposed between the resilient mounting member 240 and the housing 210.
[0041] Among them, the elastic mounting component 240 itself is elastic. After the sample container 100 is placed into the first mounting groove 220, the groove wall of the first mounting groove 220 provides elastic support for the sample container 100.
[0042] In this structure, the elastic mounting component 240 can buffer external vibrations or impacts to reduce the direct force on the sample container 100, reduce the risk of the sample container 100 tipping over due to bumps, and at the same time reduce the damage of mechanical vibration to the sample container 100 and tissue samples, further improving the posture stability and impact resistance of the sample container 100 during transportation.
[0043] In addition, a cryogenic freezing element is disposed in the first gap 230, and an elastic mounting element 240 is spaced between the cryogenic freezing element and the sample container 100, so that the cold energy of the cryogenic freezing element is evenly transferred to the sample container 100 through the elastic mounting element 240, avoiding local temperature being too low, and further improving the stability of the storage temperature of the sample container 100, so as to ensure that the biological characteristics of the tissue sample are not affected by the transportation environment.
[0044] In this embodiment, there are multiple first mounting slots 220. The multiple first mounting slots 220 are spaced apart on the elastic mounting member 240.
[0045] Multiple first mounting slots 220 are spaced apart on the elastic mounting member 240, which can simultaneously accommodate multiple sample containers 100, significantly improving the capacity and efficiency of tissue samples in a single transport and meeting the needs of batch transport.
[0046] Each sample container 100 is disposed in a first mounting slot 220. With multiple sample containers 100 spaced apart in multiple first mounting slots 220, direct contact or collision between multiple sample containers 100 can be avoided, thereby reducing the risk of containers being squeezed, rubbed or collided with each other during transportation.
[0047] In addition, each sample container 100 is independently set in the corresponding first mounting slot 220. Due to the flexible support characteristics of the elastic mounting component 240, the vibration or impact force on each sample container 100 can be dispersed and absorbed, realizing individualized buffer protection when multiple samples are transported in parallel.
[0048] In this embodiment, installation gaps are provided between the side wall of the elastic mounting member 240 and the inner side wall of the housing 210, and between the bottom surface of the elastic mounting member 240 and the bottom surface of the housing 210. The installation gaps form a first gap 230.
[0049] Specifically, in this embodiment, there are installation gaps between the side wall of the elastic mounting member 240 and the inner side wall of the box 210, and between the bottom surface and the bottom surface of the box 210. Low-temperature freezing components are provided in each installation gap, so that the low-temperature freezing components can be distributed in multiple directions around the circumference and bottom of the elastic mounting member 240 to achieve multi-directional cold energy transfer, thereby improving the uniformity and continuity of cold energy distribution inside the box 210 and avoiding the problem of local overcooling or uneven temperature gradient caused by concentrated cold source.
[0050] In this embodiment, there is also an installation gap between the top of the elastic mounting member 240 and the inner top wall of the box 210. Similarly, a low-temperature freezing component can be placed on the top of the elastic mounting member 240 to achieve all-round wrapping of the sample container 100.
[0051] Furthermore, the installation gap can also provide a buffer space for the elastic mounting component 240 during transportation bumps, thereby reducing the direct compression of the sample container 100 when the box 210 deforms, and enhancing the overall structure's compressive strength and stability.
[0052] In addition, the structure with multiple installation gaps allows for more flexible placement of the cryogenic refrigeration components, enabling them to adapt to cold sources of different sizes or shapes and improving the compatibility of the device.
[0053] It should be noted that, in this embodiment, the cryogenic freezing component is specifically an ice pack and / or an ice block.
[0054] In this embodiment, the elastic mounting member 240 is further provided with a second mounting groove 250. The second mounting groove 250 is located on one side of the first mounting groove 220 and is used to place the temperature measuring element and / or the humidity measuring element.
[0055] Specifically, in this embodiment, the second mounting slot 250 is placed on one side of the first mounting slot 220, so that the temperature measuring element and / or humidity measuring element are in an environment similar to the sample container 100 and can maintain a close spatial relationship with the sample container 100, thereby realizing real-time and accurate monitoring of the temperature and / or humidity inside or around the sample container 100.
[0056] The close proximity of the temperature and / or humidity measuring elements to the sample container 100 enables rapid reflection of temperature and / or humidity changes in the sample preservation environment, facilitating timely detection of temperature and / or humidity anomalies and intervention measures to prevent damage to tissue sample viability due to local temperature and / or humidity exceeding limits.
[0057] Similarly, the temperature measuring element and / or humidity measuring element are fixed in the second mounting groove 250 of the elastic mounting element 240 to prevent the temperature measuring element and / or humidity measuring element from shifting or falling off during transportation. The buffering effect of the elastic mounting element 240 itself reduces the interference of external vibration on the stability of the temperature measuring element and / or humidity measuring element, thus ensuring the continuity and reliability of temperature data acquisition.
[0058] In this embodiment, the tissue sample preservation device further includes a sterile bag. The sterile bag is used to fit over the sample container 100.
[0059] Sterile bags can isolate tissue samples from external environmental microorganisms, dust, or contaminants during transportation, preventing contamination due to contact with non-sterile environments. Furthermore, the sterile bags can further enhance the buffering effect during low-temperature transport, preventing tissue samples from becoming too cold.
[0060] In this embodiment, the sterile bag is made of flexible material. After wrapping the sample container 100, it can fit against the outer wall of the sample container 100 and be placed together with the sample container 100 in the first fixing groove of the elastic mounting member 240. This does not affect the stable positioning of the sample container 100 in the mounting groove, while achieving physical isolation of the sample container 100.
[0061] Specifically, the sterile bag in this embodiment includes an inner bag and an outer bag. The inner bag and the outer bag are sequentially fitted over the sample container 100 from the inside out.
[0062] In this embodiment, both the inner and outer bags are disposable. The inner and outer bags form a double-layer isolation barrier outside the sample container 100, and the disposable nature can prevent cross-contamination between different batches of tissue samples, further ensuring the reliability of the tissue samples.
[0063] In this embodiment, the tissue sample preservation device further includes a temperature and humidity sensor. The temperature and humidity sensor is disposed in the second mounting slot 250.
[0064] Specifically, the temperature and humidity sensor is integrated into the second mounting slot 250, which has the same storage conditions as the sample container 100 and maintains a close spatial relationship with the sample container 100, thereby realizing synchronous real-time monitoring of the temperature and humidity parameters of the storage environment inside the box 210.
[0065] The temperature and humidity sensor is fixed in the second mounting slot 250 of the elastic mounting component 240. This utilizes the cushioning effect of the elastic material to isolate the sensor's stability from transport vibrations, ensuring the continuity and accuracy of the monitoring data. Furthermore, its close proximity to the sample container 100 allows for precise reflection of the temperature and humidity of the sample's microenvironment, preventing localized humidity anomalies (such as condensation or excessive dryness) caused by uneven cooling distribution within the chamber 210 or external heat conduction. In the event of abnormal temperature or humidity, a timely alarm sounds to indicate that the storage conditions inside the chamber are abnormal.
[0066] In this embodiment, the elastic mounting element 240 is made of foam.
[0067] Specifically, the inherent lightweight, high elasticity, and energy-absorbing properties of foam material can provide efficient buffer protection for the sample container 100 during transportation, effectively attenuating the transmission of external vibrations or impacts and achieving a buffering function.
[0068] Meanwhile, the low thermal conductivity of the foam material reduces the heat exchange rate between the inside and outside of the enclosure 210, helping to maintain the stability of the low-temperature environment. In addition, the foam material has high plasticity and low cost, making it very suitable for use as a flexible mounting component 240.
[0069] Furthermore, in this embodiment, the sample container 100 is a tissue preservation box.
[0070] Specifically, the tissue preservation box in this embodiment includes a box body 110 and a box lid 120. The box body 110 is used to hold tissue samples, and the box lid 120 is connected to the box body 110 by a threaded connection.
[0071] The standardized structure of the tissue preservation box and its compatibility with the foam material allow it to fit snugly against the wall of the first mounting groove 220 after insertion. The friction between the groove wall and the sterile bag or tissue preservation box enhances the fixation, preventing the box from moving or tipping over during bumps. Simultaneously, it avoids irreversible foam deformation due to excessive compression, which could affect reusability.
[0072] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although this utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this utility model.
Claims
1. A tissue sample preservation device, characterized in that, include: Sample container (100) for storing tissue samples; The storage component (200) includes a box (210), the box (210) being an openable and closable structure with a holding space, the holding space being provided with a first mounting slot (220) for placing the sample container (100); The first mounting groove (220) has a groove shape that is adapted to the shape of the sample container (100), and the box (210) is provided with a first gap (230) for setting the low-temperature freezing component. The storage component (200) also includes a flexible mounting element (240); The elastic mounting member (240) is disposed in the holding space, and the first mounting groove (220) is disposed on the elastic mounting member (240); The first gap (230) of the cryogenic freezing component is located between the elastic mounting component (240) and the housing (210); The tissue sample preservation device also includes sterile bags; The sterile bag is used to fit over the sample container (100); The sterile bag includes an inner bag and an outer bag; The inner bag and the outer bag are sequentially fitted over the sample container (100) from the inside out.
2. The tissue sample preservation device according to claim 1, characterized in that, There are multiple first mounting slots (220); Multiple first mounting slots (220) are spaced apart on the elastic mounting member (240).
3. The tissue sample preservation device according to claim 1, characterized in that, There are installation gaps between the side wall of the elastic mounting member (240) and the inner side wall of the box (210), and between the bottom surface of the elastic mounting member (240) and the bottom surface of the box (210). The installation gap forms the first gap (230).
4. The tissue sample preservation device according to claim 1, characterized in that, The elastic mounting member (240) is also provided with a second mounting groove (250); The second mounting slot (250) is located on one side of the first mounting slot (220) and is used to place the temperature measuring element.
5. The tissue sample preservation device according to claim 4, characterized in that, The tissue sample preservation device also includes a temperature and humidity sensor; The temperature and humidity sensor is located in the second mounting slot (250).
6. The tissue sample preservation device according to any one of claims 2-5, characterized in that, The elastic mounting component (240) is made of foam.
7. The tissue sample preservation device according to any one of claims 1-5, characterized in that, The sample container (100) is a tissue preservation box.