Heparin sodium extracting and sterilizing device

By combining the flow guide and the fixing frame, the problem of uneven saturation in the filter area during the extraction of heparin sodium is solved, achieving uniform distribution of the solution and thorough sterilization, extending the service life of the equipment and simplifying maintenance.

CN224236247UActive Publication Date: 2026-05-15BOZHOU JUNDA BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202521192998.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-06-11
Publication Date
2026-05-15
Estimated Expiration
2035-06-11

AI Technical Summary

Technical Problem

In the current heparin sodium extraction process, the solution enters directly into one side of the filter cartridge, causing the filter cartridge area to become preferentially saturated, which easily leads to clogging, insufficient sterilization, and reduced service life of the sterilization equipment.

Method used

The flow guide frame design allows the solution to be injected tangentially and delivered to each area of ​​the filter element along a spiral path. Combined with the fixing frame and sealing structure, it ensures uniform distribution of the solution and prevents overflow, while also facilitating the replacement and cleaning of the flow guide frame.

Benefits of technology

This avoids premature saturation of certain areas of the filter element, ensures sufficient sterilization and filtration, extends the service life of the equipment, and simplifies the maintenance process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model belongs to the technical field of heparin sodium sterilization, and particularly relates to a heparin sodium extracting and sterilizing device which comprises a filter cartridge and a filter cover at the upper end of the filter cartridge, a liquid injection pipe facing forwards is fixed to the right side of the filter cover, a coaxial filter element is arranged in the filter cartridge, a coaxial flow guide frame is arranged on the outer side of the filter element, and the flow guide frame is spirally wound on the outer side of the filter element from top to bottom; a fixing frame is arranged at the upper end of the flow guide frame, a positioning hole is formed in the upper end of the fixing frame and used for being in butt joint with a jacking mechanism in the filter cover, and a sealing plate extends out of the outer side of the upper end of the fixing frame and is fixedly connected with an outer side plate of the flow guide frame. When the cylindrical sterilizing and filtering equipment provided by the utility model is used, a solution can be tangentially injected into the cylindrical sterilizing and filtering equipment and flows along a spiral path, so that the solution is conveyed to different areas of the filter element, the condition that part of the areas of the filter element are saturated in advance is avoided, and meanwhile, thrust can be formed on the solution in the saturated areas; and the water flows to other areas and continuously enters the filter element.
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Description

Technical Field

[0001] This utility model belongs to the field of heparin sodium sterilization technology, and in particular relates to a heparin sodium extraction and sterilization device. Background Technology

[0002] Sodium heparin is a naturally occurring acidic mucopolysaccharide anticoagulant. It is the most widely used anticoagulant (blood thinner) in modern medicine and one of the most important emergency drugs in clinical practice. It is mainly extracted from mammalian mucosal tissues (pig small intestinal mucosa, bovine lungs) and is processed into sterile products through sterile filtration and strict aseptic operation and packaging.

[0003] Currently, during sterilization filtration, the solution directly enters one side of the filter cartridge, causing the filter cartridge in that area to saturate preferentially compared to other areas. This leads to clogging and insufficient sterilization filtration, and also reduces the lifespan of the sterilization equipment.

[0004] To address the aforementioned issues, this application proposes a heparin sodium extraction and sterilization apparatus. Utility Model Content

[0005] The purpose of this invention is to provide a heparin sodium extraction and sterilization device, which solves the problems mentioned in the background art.

[0006] To solve the above-mentioned technical problems, this utility model is achieved through the following technical solution:

[0007] This utility model is a heparin sodium extraction and sterilization device, including a filter cylinder and a filter cover at its upper end;

[0008] The filter cover has a forward-facing injection tube fixed on its right side. The filter cylinder has a coaxial filter element inside and a coaxial flow guide on the outside of the filter element. The flow guide is spirally wound around the outside of the filter element from top to bottom.

[0009] The upper end of the flow guide frame is provided with a fixing frame, and the upper end of the fixing frame is provided with a positioning hole for connecting with the tightening mechanism inside the filter cover. A sealing plate extends out from the upper outer side of the fixing frame and is fixedly connected to the outer side plate of the flow guide frame.

[0010] Preferably, the lower plate of the flow guide frame abuts against the outer wall of the filter element, and the upper plate is an upper pressure plate with a width half that of the lower plate.

[0011] Preferably, the inner side of the upper pressure plate extends downward with a side plate, forming an opening structure between it and the lower plate.

[0012] Preferably, a spiral cavity is formed between the upper and lower layers of the flow guide frame and the side plate, and one end of the injection tube extends into the interior of the spiral cavity.

[0013] Preferably, the opening between the side plate and the flow guide in the area where the injection tube is located is sealed by the outer wall of the fixing frame.

[0014] Preferably, the lower end of the filter cover is circumferentially distributed with positioning sleeves, and a connecting rod is inserted into the lower end of the filter cover, with a plug rod extending from the lower end of the connecting rod.

[0015] Preferably, the plug rod is engaged with the interior of the positioning hole.

[0016] This utility model has the following beneficial effects:

[0017] This invention utilizes a built-in flow guide frame combined with tangentially injected solution to allow the solution to be circumferentially transferred to different areas along the spiral cavity after entering the filter element. This ensures that the solution enters the filter element in different areas, preventing premature saturation of some areas of the filter element, ensuring sufficient sterilization and filtration, and extending the service life of the equipment.

[0018] This utility model uses a combination structure of filter cartridge and filter cover, which is directly fixed inside the filter cartridge and filter cover by positioning sleeve and fixing bracket, and seals the upper area. When replacing the filter element, the guide frame can be directly removed for cleaning. The structure is simple and convenient for long-term maintenance.

[0019] Of course, any product implementing this utility model does not necessarily need to achieve all of the advantages described above at the same time. Attached Figure Description

[0020] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0021] Figure 1 This is a schematic diagram of the overall appearance structure of this utility model;

[0022] Figure 2 This is a schematic diagram of the internal three-dimensional structure of the upper end of the filter cartridge of this utility model;

[0023] Figure 3 This is a schematic diagram of the internal planar structure of the upper end of the filter cartridge of this utility model;

[0024] Figure 4 This is a partially enlarged structural diagram of part A of this utility model;

[0025] The attached diagram lists the components represented by each number as follows:

[0026] In the picture:

[0027] 11. Filter cartridge; 12. Filter cover; 13. Liquid injection tube; 14. Filter element; 15. Flow guide; 16. Fixing bracket;

[0028] 121. Positioning sleeve; 122. Connecting rod; 1221. Plug rod; 151. Upper pressure plate; 152. Side plate; 153. Spiral cavity; 161. Sealing plate; 162. Positioning hole. Detailed Implementation

[0029] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0030] In the description of this utility model, it should be understood that the terms "opening", "upper", "lower", "thickness", "top", "middle", "length", "inner", "around" and other terms indicating orientation or positional relationship are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the components or elements referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0031] Please see Figure 1-4 As shown, this utility model is a heparin sodium extraction and sterilization device, including a filter cylinder 11 and a filter cover 12 at its upper end;

[0032] A forward-facing injection tube 13 is fixed to the right side of the filter cover 12, forming a tangential tube structure. The other end extends into the interior of the filter cover 12. A coaxial filter element 14 is provided inside the filter cylinder 11. A coaxial flow guide 15 is provided on the outside of the filter element 14. The flow guide 15 is spirally wound around the outside of the filter element 14 from top to bottom. The other end of the injection tube 13 is located above the top area of ​​the flow guide 15. The injected solution is transmitted to various areas of the filter element 14 through the spiral structure of the flow guide 15.

[0033] The upper end of the flow guide 15 is provided with a fixing frame 16, the inner wall of which is attached to the outer wall of the filter element 14 frame. The upper end of the fixing frame 16 is provided with a positioning hole 162 for connecting with the tightening mechanism inside the filter cover 12. The tightening mechanism and the fixing frame 16 are both provided at the bottom of the filter cylinder 11. The upper end of the fixing frame 16 extends outward with a sealing plate 161 which is fixedly connected to the outer plate of the flow guide 15 to seal the upper area of ​​the flow guide 15.

[0034] Furthermore, the lower plate of the flow guide 15 abuts against the outer wall of the filter element 14, and the upper plate is the upper pressure plate 151, which is half the width of the lower plate. The upper pressure plate 151 is connected and fixed by the outer plate of the flow guide 15. The inner side of the upper pressure plate 151 extends downward with a side plate 152, forming an opening structure between it and the lower plate. When the solution is spirally conveyed, the solution automatically enters the filter element 14 through this opening.

[0035] Furthermore, a spiral cavity 153 is formed between the upper and lower layers of the flow guide frame 15 and the side plate 152. One end of the injection tube 13 extends into the interior of the spiral cavity 153. The flow force of the solution inside the spiral cavity 153 is greater than that of the solution in the outer area of ​​the side plate 152. When the solution in the outer area encounters a blockage and cannot directly enter the filter element 14, the flow of the external solution drives the internal solution to continue to flow, thereby entering the filter element 14 in other areas.

[0036] Furthermore, the opening between the side plate 152 and the flow guide 15 in the area where the injection tube 13 is located is sealed by the outer wall of the fixing frame 16 to prevent the solution from overflowing upwards after injection.

[0037] Furthermore, a positioning sleeve 121 is circumferentially distributed at the lower end of the filter cover 12, and a connecting rod 122 is inserted into its lower end. A plug rod 122 extends from the lower end of the connecting rod 122. The positioning sleeve 121, the connecting rod 122 and the plug rod 1221 at its lower end combine to form a tightening mechanism. The plug rod 1221 is engaged with the inside of the positioning hole 162. While installing the fixing frame 16 into the predetermined area, it disperses the tightening stress and prevents the flow guide frame 15 from deforming.

[0038] It is understood that when the cylindrical sterilization and filtration device provided by this utility model is in use, the solution can be injected tangentially into the interior and made to flow along a spiral path, thereby delivering it to different areas of the filter element 14. This avoids the situation where some areas of the filter element 14 become saturated in advance. At the same time, it can also generate a thrust on the solution in the already saturated areas, causing it to flow to other areas and continue to enter the filter element 14, thereby ensuring that the filter element 14 is fully utilized.

[0039] A specific application of the operation process in this embodiment is as follows: During use, the solution is injected tangentially into the interior of the filter cover 12 through the injection tube 13 and flows into the interior of the spiral cavity 153. Subsequently, the continuous injection of the solution creates a thrust, causing the solution to flow along its edge inside the spiral cavity 153, thereby entering the filter element 14 at different positions, thus avoiding premature saturation of local areas of the filter element 14. At the same time, the continuous injection of the solution can also create a thrust on some of the solution that has stagnated due to blockage, causing it to flow to other areas for sterilization filtration, thereby ensuring the uniformity of adsorption saturation in all areas of the filter element 14. In addition, the fixing frame 16 and the sealing plate 161 on the outer side of its upper end can directly fit the guide frame 15 onto the outer side of the filter element 14 during installation, and then the connecting rod 1221 is connected to the positioning hole 162 to form a fixation, while sealing the upper area to prevent unfiltered solution from overflowing upwards. When the filter element 14 is saturated and needs to be replaced, the guide frame 15 can be directly removed for cleaning or replacement, which is convenient for daily maintenance and other operations during long-term use.

[0040] In the description of this specification, references to terms such as "an embodiment," "example," and "specific example" indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0041] The preferred embodiments of this utility model disclosed above are merely illustrative of the present utility model. These preferred embodiments do not exhaustively describe all details, nor do they limit the utility model to the specific implementations described. Clearly, many modifications and variations can be made based on the content of this specification. This specification selects and specifically describes these embodiments to better explain the principles and practical applications of this utility model, thereby enabling those skilled in the art to better understand and utilize it. This utility model is limited only by the claims and their full scope and equivalents.

Claims

1. A heparin sodium extraction and sterilization device, characterized in that: Includes filter cartridge (11) and filter cover (12) at its upper end; The filter cover (12) has a forward-facing injection tube (13) fixed on the right side. The filter cylinder (11) has a coaxial filter element (14) inside. The filter element (14) has a coaxial flow guide (15) on the outside. The flow guide (15) is spirally wound around the outside of the filter element (14) from top to bottom. The upper end of the flow guide (15) is provided with a fixed frame (16), and the upper end of the fixed frame (16) is provided with a positioning hole (162) for connecting with the tightening mechanism inside the filter cover (12). A sealing plate (161) extends out from the upper outer side of the fixed frame (16) and is fixedly connected to the outer side plate of the flow guide (15).

2. The heparin sodium extraction and sterilization apparatus according to claim 1, characterized in that: The lower plate of the flow guide (15) abuts against the outer wall of the filter element (14), and the upper plate is the upper pressure plate (151), which is half the width of the lower plate.

3. The heparin sodium extraction and sterilization apparatus according to claim 2, characterized in that: The inner side of the upper pressure plate (151) extends downward with a side plate (152), forming an opening structure between it and the lower plate.

4. The heparin sodium extraction and sterilization apparatus according to claim 3, characterized in that: A spiral cavity (153) is formed between the upper and lower layers of the flow guide (15) and the side plate (152), and one end of the injection tube (13) extends into the interior of the spiral cavity (153).

5. The heparin sodium extraction and sterilization apparatus according to claim 4, characterized in that: The opening between the side plate (152) of the area where the injection tube (13) is located and the flow guide (15) is sealed by the outer wall of the fixing frame (16).

6. The heparin sodium extraction and sterilization apparatus according to claim 1, characterized in that: The filter cover (12) has a positioning sleeve (121) distributed circumferentially at its lower end, and a connecting rod (122) is inserted into its lower end. A plug rod (1221) extends out from the lower end of the connecting rod (122).

7. The heparin sodium extraction and sterilization apparatus according to claim 6, characterized in that: The plug rod (1221) is engaged with the interior of the positioning hole (162).