Chuck suitable for large tissue embedding frame and pathological slicer

The inverted clamp design solves the problem of the embedding frame loosening during the sectioning process in large tissue microtome chucks, achieving a highly efficient and stable sectioning process and improving the sectioning quality and efficiency in pathology departments.

CN224266832UActive Publication Date: 2026-05-22JINHUA KELATAI INSTR CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
JINHUA KELATAI INSTR CO LTD
Filing Date
2025-04-10
Publication Date
2026-05-22

AI Technical Summary

Technical Problem

The chucks of existing large tissue microtome machines are prone to causing the embedding frame to loosen during the sectioning process, resulting in section skipping or wax erosion, which affects the sectioning quality and efficiency.

Method used

A clamp suitable for large tissue embedding frames was designed, employing an inverted jaw structure and a jaw opening adjustment device to ensure that the embedding frame is tightly attached to the base surface and prevents loosening.

Benefits of technology

It effectively prevents the embedding frame from loosening, avoids slide skipping and wax erosion, improves slide quality and work efficiency, and reduces the workload of slide technicians.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a chuck suitable for a large tissue embedding frame and a pathological slicer, the chuck suitable for the large tissue embedding frame comprises a base with a fixed jaw, a movable jaw and a jaw opening degree adjusting device, the movable jaw is installed on the base with the fixed jaw through the jaw opening degree adjusting device, and the movable jaw is installed on the base with the fixed jaw through the jaw opening degree adjusting device. And a jaw of an inverted buckling structure with a small outer end opening and a large inner end opening is formed between the movable jaw and the fixed jaw. According to the utility model, the embedding frame is contained in the jaw by virtue of the jaw with the inverted buckling structure, and the embedding frame can be tightly attached to the inner surface of the base after being clamped, so that the phenomenon that the embedding frame is loosened in a slicing process is prevented.
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Description

Technical Field

[0001] This utility model belongs to the technical field of specimen tissue clamping devices for pathological slicers, specifically relating to a clamp suitable for large tissue embedding frames and a pathological slicer. Background Technology

[0002] Among various biological tissue specimens in pathological sections, some large tissues are encountered, such as whole sections of the prostate and sections from ESD (electrode dissection). Previously, these large tissues could not be sectioned on ordinary rotary microtome and required a push-type microtome. However, push-type microtome cannot achieve continuous sectioning, resulting in low efficiency and failing to meet the high workload demands of pathology departments. With advancements in rotary microtome technology, continuous sectioning of these large tissues is now possible, although this requires a corresponding large clamp. Currently, common large clamps on the market generally include a base with fixed jaws, movable jaws, and a jaw opening adjustment device. The fixed and movable jaws have transverse anti-slip teeth / grooves and are arranged parallel to each other. However, due to manufacturing precision issues and the susceptibility of the plastic embedding frame to deformation, the originally parallel jaws and the plastic embedding frame can form an outward "V" shape. This causes the plastic embedding frame to loosen during sectioning, leading to skipped sections or even wax stripping, severely impacting section quality and work efficiency.

[0003] In response, some industry professionals have made improvements. Chinese patent CN214538848U discloses a paraffin large tissue section clamp, comprising a fixed clamping body, a movable clamping body slidably fitted onto the base plate of the fixed clamping body, and a guide-fitted connection between the movable clamping body and the fixed clamping body. A main directional groove is provided in the middle of the base plate of the fixed clamping body. A main positioning protrusion integrally connected to the bottom of the movable clamping body guides and fits into the main directional groove. An adjusting screw is fixedly connected to the movable clamping body, the adjusting screw being placed in the main directional groove and extending beyond the outer end of the fixed clamping body, and threadedly connected to an adjusting nut. A washer is provided between the threaded sleeve of the adjusting nut and the fixed clamping body. Clamping blocks are slidably arranged at both ends of the clamping surface of the fixed clamping body and at both ends of the clamping surface of the movable clamping body, and the clamping blocks at the fixed clamping body and the clamping blocks at the movable clamping body are respectively connected by springs. This patent increases the stability of the clamping mechanism for large paraffin tissue blocks, reducing vibrations, block loosening, and damage during sectioning, ensuring section stability, enabling continuous sectioning, improving block detection utilization, and reducing waste. However, the patent's structure is overly complex. Furthermore, the clamping blocks at both ends of the fixed clamping body and the movable clamping body are slidably mounted, and the clamping blocks at the fixed and movable clamping bodies are connected by springs. This primarily addresses the issue of lateral / left-right displacement of the embedding frame. However, in actual sectioning, the embedding frame is mainly subjected to longitudinal / front-back shear forces. Therefore, this patent does not truly solve the main problems and contradictions existing in the prior art. Summary of the Invention

[0004] To overcome the shortcomings of existing technologies, this utility model proposes a clamp and pathological slicer suitable for large tissue embedding frames, which prevents the embedding frames from loosening during the slide preparation process, avoids slide skipping or even wax erosion, improves the slide quality and work efficiency of pathology departments, and reduces the workload of slide technicians.

[0005] The technical solution adopted in this utility model is:

[0006] A clamp for large tissue embedding frames includes a base with fixed jaws, movable jaws, and a jaw opening adjustment device. The movable jaws are mounted on the base with fixed jaws via the jaw opening adjustment device. The movable jaws and fixed jaws form an inverted jaw structure with a small outer opening and a large inner opening. This invention uses the inverted jaw structure to enclose the embedding frame within the jaws, ensuring the embedding frame is tightly clamped against the inner surface of the base and preventing loosening during sectioning.

[0007] Furthermore, the base with fixed jaws is a figure-7 shaped integrated structure, including a longitudinally arranged base body and a horizontally arranged fixed jaw. The base body has a longitudinal sliding groove, and the fixed jaw has a through hole that is parallel to the longitudinal sliding groove. The movable jaw is slidably connected to the longitudinal sliding groove.

[0008] Furthermore, the jaw opening adjustment device includes a screw and an adjustment knob. One end of the screw is connected to the movable jaw, and the other end passes through the through hole and is screwed to the adjustment knob. By rotating the adjustment knob, the movable jaw moves up and down along the longitudinal slide groove and then cooperates with the fixed jaw to clamp or loosen the embedding frame.

[0009] Furthermore, the length of the fixed jaw and the movable jaw protruding from the base is greater than the thickness of the embedding frame.

[0010] Furthermore, the included angles between the fixed jaws, the movable jaws, and the base are all less than 90°; or the included angle between the fixed jaws and the base is less than 90°, and the included angle between the movable jaws and the base is equal to 90°; or the included angle between the fixed jaws and the base is equal to 90°, and the included angle between the movable jaws and the base is less than 90°, so that the movable jaws and the fixed jaws can form a jaw with an inverted buckle structure with a small outer opening and a large inner opening.

[0011] Furthermore, the inner surface of the fixed jaws and / or the movable jaws is provided with an anti-slip portion.

[0012] Furthermore, the longitudinal groove is a T-shaped groove or a dovetail groove, and the sliding part of the corresponding movable jaw is T-shaped or dovetail-shaped.

[0013] Furthermore, the screw and the movable jaw are fixedly connected, and are positioned by an interference fit and a limiting pin to prevent the screw and the movable jaw from loosening; or, the screw and the movable jaw are hinged, so that the movable jaw can adjust its parallelism with the fixed jaw on its own.

[0014] Furthermore, a slider is fixed on the back of the base to facilitate quick assembly and disassembly of the chuck, enabling the microtome to quickly switch to a conventional chuck for slicing conventional tissues when not cutting large tissues, thereby improving the utilization rate of the microtome.

[0015] A pathological microtome includes a microtome base on which a feeding device is mounted, and the aforementioned chuck suitable for large tissue embedding frames is detachably mounted on the feeding device.

[0016] The beneficial effects of this utility model are as follows: The clamp jaws, which form an inverted structure with a small outer opening and a large inner opening between the movable clamp jaws and the fixed clamp jaws, allow the embedding frame to be contained within the clamp jaws. After the embedding frame is clamped, it can fit tightly against the surface of the base, preventing the embedding frame from loosening during the slide preparation, avoiding slide skipping or even wax erosion, improving the slide quality and work efficiency of the pathology department, and reducing the workload of slide preparation technicians. Attached Figure Description

[0017] Figure 1 This is an exploded structural diagram of the present invention.

[0018] Figure 2 This is a side view structural diagram of one embodiment of the present invention.

[0019] Figure 3 This is a schematic diagram of the structure of this utility model in use.

[0020] Figure 4 yes Figure 3 A side view structural diagram.

[0021] In the figure: 1. Movable jaws, 1a. Anti-slip part of movable jaws, 1b. Sliding part, 2. Screw, 3. Base with fixed jaws, 3a. Fixed jaws, 3b. Longitudinal groove, 3c. Through hole, 3d. Anti-slip part of fixed jaws, 3e. Seat, 3f. Back side, 4. Adjustment knob, 5. Slider, 6. Embedding frame. Detailed Implementation

[0022] The present invention will be further described below with reference to specific embodiments, but the present invention is not limited to these specific embodiments. Those skilled in the art should recognize that the present invention covers all alternatives, improvements and equivalents that may be included within the scope of the claims.

[0023] In the description of this utility model, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "clockwise," and "counterclockwise," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined with "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, unless otherwise stated, "a plurality of" means two or more, unless otherwise expressly defined.

[0024] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0025] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0026] Example 1

[0027] See Figure 1-4This embodiment provides a clamp suitable for large tissue embedding frames, including a base 3 with fixed jaws, movable jaws 1, and a jaw opening adjustment device. The movable jaws 1 are mounted on the base 3 with fixed jaws via the jaw opening adjustment device. The movable jaws 1 and the fixed jaws 3a form an inverted jaw structure with a small outer opening and a large inner opening. This invention uses the inverted jaw structure to enclose the embedding frame 6 within the jaws. After clamping, the embedding frame 6 can tightly adhere to the surface of the base, preventing the embedding frame from loosening during sectioning.

[0028] The base 3 with fixed jaws described in this embodiment is a "7"-shaped integrated structure, including a longitudinally arranged base body 3e and a horizontally arranged fixed jaw 3a. The base body 3e has a longitudinal sliding groove 3b, and the fixed jaw 3a has a through hole 3c that is parallel to and penetrates the longitudinal sliding groove 3b. The movable jaw 1 is slidably connected to the longitudinal sliding groove 3b. Specifically, the movable jaw 1 has a sliding part 1b, which is installed in the longitudinal sliding groove 3b. By moving the sliding part 1b within the longitudinal sliding groove 3b, the movable jaw 1 can move up and down.

[0029] The longitudinal groove 3b is a T-shaped groove or a dovetail groove, and the corresponding sliding part 1b of the movable jaw 1 is T-shaped or dovetail-shaped.

[0030] The jaw opening adjustment device described in this embodiment includes a screw 2 and an adjustment knob 4. One end of the screw 2 is connected to the movable jaw 1, and the other end passes through the through hole 3c and is screwed to the adjustment knob 4. By rotating the adjustment knob 4, the movable jaw 1 is controlled to move up and down along the longitudinal sliding groove 3b and engage with the fixed jaw 3a to clamp or release the embedding frame 6. Specifically, the screw 2 and the movable jaw 1 are fixedly connected, and are positioned by an interference fit and a limiting pin to prevent the screw 2 from loosening from the movable jaw 1. Of course, the screw 2 can also be hinged to the movable jaw 1, so that the movable jaw 1 can adjust its parallelism with the fixed jaw 3a on its own.

[0031] In this embodiment, the lengths of the fixed jaw 3a and the movable jaw 1 protruding from the base 3e are greater than the thickness of the embedding frame 6, thus allowing the embedding frame 6 to be contained within the jaws. The included angles between the fixed jaw 3a, the movable jaw 1, and the base 3e are all less than 90°, preferably 85°, thereby forming a jaw structure with a small outer opening and a large inner opening between the movable jaw and the fixed jaw. Alternatively, the included angle between the fixed jaw 3a and the base 3e can be less than 90°, and the included angle between the movable jaw 1 and the base 3e can be equal to 90°; or the included angle between the fixed jaw 3a and the base 3e can be equal to 90°, and the included angle between the movable jaw 1 and the base 3e can be less than 90°.

[0032] In this embodiment, the inner surfaces of the fixed jaw 3a and / or the movable jaw 1 are provided with anti-slip portions. Specifically, the anti-slip portion 3d of the fixed jaw is an anti-slip texture or anti-slip mesh pattern arranged longitudinally along its width direction, and the anti-slip portion 1a of the movable jaw is an anti-slip texture or anti-slip mesh pattern arranged longitudinally along its width direction.

[0033] In this embodiment, a slider 5 is fixedly provided on the back side 3f of the base 3e, which facilitates quick disassembly and assembly of the chuck. This allows the microtome to quickly switch to a conventional chuck for sectioning conventional tissues when not cutting large tissues, thereby improving the utilization rate of the microtome.

[0034] The movable jaw 1 and the fixed jaw 3a of this utility model form an inverted jaw structure with a small outer opening and a large inner opening, so that the embedding frame 6 is contained within the jaw. After the embedding frame 6 is clamped, it can stick tightly to the surface of the base, preventing the embedding frame 6 from becoming loose in the slide, avoiding the occurrence of slide skipping or even wax biting, improving the slide quality and work efficiency of the pathology department, and reducing the workload of slide technicians.

[0035] Example 2

[0036] This embodiment provides a pathological microtome, including a microtome base, on which a feeding device and a blade holder base are mounted. The blade holder base is provided with a blade holder, and a chuck suitable for large tissue embedding frames is detachably mounted on the feeding device.

[0037] The chuck for large tissue embedding frames described in this embodiment can be detachably installed on the feeding device via a slider 5 fixed to the back 3f of the base 3e, which facilitates quick assembly and disassembly of the chuck. This allows the microtome to quickly switch to a conventional chuck for sectioning conventional tissues when not cutting large tissues, thereby improving the utilization rate of the microtome.

[0038] The remaining structures and functions of the clamp for large tissue embedding frames described in this embodiment can be referred to in Embodiment 1.

Claims

1. A gripper suitable for large tissue embedding frames, comprising a base with fixed jaws, movable jaws, and a jaw opening adjustment device, wherein the movable jaws are mounted on the base with fixed jaws via the jaw opening adjustment device, characterized in that: The movable jaws and the fixed jaws form an inverted jaw structure with a small outer opening and a large inner opening.

2. The clamp for large tissue embedding frames according to claim 1, characterized in that: The base with fixed jaws is a "7"-shaped integrated structure, including a longitudinally arranged base body and a horizontally arranged fixed jaw. The base body has a longitudinal sliding groove, and the fixed jaw has a through hole that is parallel to the longitudinal sliding groove. The movable jaw is slidably connected to the longitudinal sliding groove.

3. A clamp suitable for large tissue embedding frames according to claim 2, characterized in that: The jaw opening adjustment device includes a screw and an adjustment knob. One end of the screw is connected to the movable jaw, and the other end passes through the through hole and is screwed to the adjustment knob. By rotating the adjustment knob, the movable jaw moves up and down along the longitudinal slide groove and then cooperates with the fixed jaw to clamp or loosen the embedding frame.

4. A clamp suitable for large tissue embedding frames according to claim 2, characterized in that: The length of the fixed jaws and movable jaws protruding from the base is greater than the thickness of the embedding frame.

5. A clamp suitable for large tissue embedding frames according to claim 1, characterized in that: The included angles between the fixed jaws, the movable jaws, and the base are all less than 90°; or the included angle between the fixed jaws and the base is less than 90°, and the included angle between the movable jaws and the base is equal to 90°; or the included angle between the fixed jaws and the base is equal to 90°, and the included angle between the movable jaws and the base is less than 90°.

6. A clamp suitable for large tissue embedding frames according to claim 1, characterized in that: The inner surfaces of the fixed jaws and / or the movable jaws are provided with anti-slip parts.

7. A clamp suitable for large tissue embedding frames according to claim 2, characterized in that: The longitudinal groove is a T-shaped groove or a dovetail groove, and the sliding part of the corresponding movable jaw is T-shaped or dovetail-shaped.

8. A clamp suitable for large tissue embedding frames according to claim 3, characterized in that: The screw and the movable jaw are fixedly connected and positioned by an interference fit and a limit pin; or the screw and the movable jaw are hinged, allowing the movable jaw to adjust its parallelism with the fixed jaw.

9. A clamp suitable for large tissue embedding frames according to claim 2, characterized in that: A slider is fixed to the back of the base.

10. A pathological microtome, comprising a microtome base, wherein a feeding device is mounted on the microtome base, characterized in that: The chuck for large tissue embedding frames according to any one of claims 1-9 is detachably mounted on the feeding device.