A rapid detection device for recombinant protein Eg FABP1 with a flow equalization structure

Abstract

This utility model relates to a rapid detection device for recombinant protein Eg FABP1 with a uniform flow structure, comprising an upper plate, a lower plate, and test strips. An upper pressure frame is integrally formed in the transverse middle of the upper plate, with the lower end of the upper pressure frame protruding from the lower surface of the upper plate. A ring pressure platform is integrally formed on the lower right surface of the upper plate, with a drip hole starting in the middle of the ring pressure platform. The upper surface of the lower plate has grooves starting in the middle and right side, with a collection groove, a drainage groove, and a distribution groove on the bottom surface of the grooves. The collection groove is located at the right end of the drainage groove and is interconnected. The distribution groove connects the front and rear edges of the drainage groove. An exudate layer is laid in the grooves. A suspension containing recombinant protein is introduced into the collection groove through the drip hole, and then the liquid flow is distributed through the drainage and distribution grooves. Finally, the exudate layer guides the liquid evenly to the test strip, making the wetting and flow of the suspension on the test strip more uniform and rapid, greatly shortening the wetting and detection time of the test strip.

Description

Technical Field

[0001] This utility model relates to the field of detection device technology, specifically a rapid detection device for recombinant protein EgFABP1 with a flow equalization structure. Background Technology

[0002] Recombinant protein detection typically employs external catalysis in a solution environment. Although recombinant proteins are long-chain macromolecules, they still require microscopic observation on a macroscopic scale. Detection of recombinant proteins generally uses protein target reactions or protein antibody reactions for feedback detection. However, these reactions require specific environments such as containers and temperatures, and the detection time is long. Therefore, rapid detection devices are generally used for testing. However, existing rapid detection devices are generally simple in structure, using test strips to wet and guide the suspension containing recombinant proteins. This process results in a slow liquid flow rate and uneven liquid distribution, leading to a long waiting time.

[0003] Therefore, it is necessary to design a rapid detection device for the recombinant protein Eg FABP1 with a uniform flow structure. Utility Model Content

[0004] The purpose of this invention is to provide a rapid detection device for recombinant protein Eg FABP1 with a uniform flow structure to solve the problems mentioned in the background art.

[0005] To solve the above-mentioned technical problems, this utility model provides the following technical solution:

[0006] A rapid detection device for recombinant protein Eg FABP1 with a uniform flow structure includes an upper plate, a lower plate, and test strips. An upper pressure frame is integrally formed in the transverse middle of the upper plate, with the lower end of the upper pressure frame protruding from the lower surface of the upper plate. A ring pressure platform is integrally formed on the lower right surface of the upper plate, with a drip hole starting in the middle of the ring pressure platform. The upper surface of the lower plate has grooves starting in the middle and right side, with a collection groove, a drainage groove, and a diversion groove on the bottom surface of the grooves. The collection groove is located at the right end of the drainage groove and is interconnected. The diversion groove connects the front and rear edges of the drainage groove. An exudate layer is laid in the grooves. The test strip is laid on the upper surface of the lower plate and the upper surface of the exudate layer. The test strip and the lower pressure frame cooperate with each other. Markings are engraved on a portion of the upper surface of the upper plate.

[0007] According to the above technical solution, a positioning ring is integrally formed on the left half of the upper surface of the lower plate, the test paper is embedded in the positioning ring, and the upper pressure frame is fitted with the positioning ring and presses the outer edge of the test paper.

[0008] According to the above technical solution, the width of the test strip is 1.25 to 1.3 times the width of the permeate layer.

[0009] According to the above technical solution, the length of the front and rear ends of the diversion channel is 0.75 to 0.8 times the width of the permeate layer.

[0010] According to the above technical solution, the right end of the permeation layer is pressed by the ring pressure platform, and the dripping hole and the liquid collection tank cooperate with each other.

[0011] According to the above technical solution, the overlap length between the test strip and the seepage layer is one-half to two-thirds of the length of the test strip.

[0012] Compared with the prior art, the beneficial effects achieved by this utility model are:

[0013] The suspension containing recombinant protein is introduced into the collection tank through the dropper hole, and then the liquid flow is distributed through the diversion and distribution channels. Finally, the liquid is guided to the test paper through the permeation layer, making the wetting and flow of the suspension on the test paper more uniform and rapid, which greatly shortens the wetting and detection time of the test paper. Attached Figure Description

[0014] The accompanying drawings are provided to further illustrate the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention, but do not constitute a limitation thereof. In the drawings:

[0015] Figure 1 This is a three-dimensional structural schematic diagram of this utility model from one perspective;

[0016] Figure 2 This is a schematic diagram of the main sectional structure of this utility model;

[0017] Figure 3 This is a three-dimensional structural diagram of the upper plate of this utility model from one perspective;

[0018] Figure 4 This is a three-dimensional structural diagram of the lower plate of this utility model from one perspective;

[0019] Figure 5 This is a schematic diagram of the composite structure of the test paper and the seepage layer of this utility model.

[0020] In the diagram: 1. Upper plate, 2. Lower plate, 3. Test paper, 4. Drip hole, 5. Marking mark, 6. Upper pressure frame, 7. Ring pressure platform, 8. Positioning ring, 9. Embedded groove, 10. Liquid collection tank, 11. Drainage groove, 12. Diversion groove, 13. Permeation layer. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] Example 1

[0023] Please see Figure 1-5 This utility model provides a technical solution: a recombinant protein Eg with a homogenization structure. The FABP1 rapid testing device includes an upper plate 1, a lower plate 2, and test strips 3. An upper pressure frame 6 is integrally formed in the middle of the horizontal axis of the upper plate 1, with the lower end of the upper pressure frame 6 protruding from the lower surface of the upper plate 1. A ring pressure platform 7 is integrally formed on the lower right surface of the upper plate 1, with a drip hole 4 starting from the center of the ring pressure platform 7. The upper surface of the lower plate 2 has grooves 9 starting from the center and right side. The bottom surface of the grooves 9 has a collection tank 10, a drainage tank 11, and a diversion tank 12. The collection tank 10 is located at the right end of the drainage tank 11 and is interconnected. The diversion tank 12 connects the front and rear edges of the drainage tank 11. An exudate layer 13 is laid in the grooves 9. The test strips 3 are laid on the upper surface of the lower plate 2 and the upper surface of the exudate layer 13. The test strips 3 and the lower pressure frame cooperate with each other. Marking marks 5 are engraved on a portion of the upper surface of the upper plate 1.

[0024] The upper plate 1 and lower plate 2 form the main supporting structure of the device. The upper pressure frame 6 constructs the observation window and presses and fixes the test strip 3 through the lower protrusion structure. The test strip 3 is soaked with test reagent. The ring pressure platform 7 provides a forming space for the drip hole 4. The groove 9 provides a placement space for the seepage layer 13 and provides a starting space for the collection tank 10, the drainage groove 11, and the diversion groove 12. The collection tank 10 collects the liquid flow introduced by the drip hole 4. The drainage groove 11 guides the liquid flow to the other end. The diversion groove 12 guides the liquid flow in the drainage groove 11 to both sides, thereby allowing the seepage layer 13 to have a larger area of ​​drainage and penetration, ensuring a larger area of ​​drainage and wetting of the test strip 3, and improving the liquid flow rate. The marking mark 5 displays the test results.

[0025] Specifically, the upper left half of the lower plate 2 is integrally formed with a positioning ring 8, the test paper 3 is embedded in the positioning ring 8, the upper pressure frame 6 is fitted with the positioning ring 8, and presses the outer edge of the test paper 3.

[0026] The test strip 3 is positioned by the positioning ring 8, and at the same time, the pressure frame 6 effectively positions and presses the test strip 3 to avoid misalignment of the test strip 3, which would lead to detection errors.

[0027] Specifically, the width of the test strip 3 is 1.25 to 1.3 times the width of the permeation layer 13.

[0028] By setting the relative width between the test paper 3 and the seepage layer 13, the uniformity of the seepage is ensured, and oversaturation at the edges is avoided.

[0029] Specifically, the length of the front and rear ends of the diversion channel 12 is 0.75 to 0.8 times the width of the permeate layer 13.

[0030] By setting the relative width of the diversion channel 12 and the permeate layer 13, the liquid flow can more evenly wet the permeate layer 13.

[0031] Specifically, the ring pressure platform 7 presses the right end of the permeate layer 13, and the drip hole 4 cooperates with the liquid collection tank 10.

[0032] This allows the recombinant protein suspension to enter the collection tank 10 more effectively, avoiding excessive external seepage.

[0033] Specifically, the overlap length of the test strip 3 and the seepage layer 13 is one-half to two-thirds of the length of the test strip 3.

[0034] By setting the overlap length, the wetting speed of the liquid flow on the test paper 3 is ensured, while avoiding any impact on the test results.

[0035] Working principle: When in use, after the suspension containing recombinant protein is dropped onto the drop hole 4, the suspension will seep downward into the collection tank 10. Then the suspension will flow along the guide tank 11 and the diversion tank 12, and at the same time seep into the seepage layer 13. When the seepage layer 13 is saturated, it will quickly and extensively wet the test paper 3, ensuring that the test paper 3 is effectively wetted and cultured. Then, the detection unit can detect the recombinant protein.

[0036] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0037] Finally, it should be noted that the above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A rapid detection device for recombinant protein Eg FABP1 with a uniform flow structure, comprising an upper plate (1), a lower plate (2), and a test strip (3), characterized in that: The upper plate (1) has an integral upper pressure frame (6) in the middle of its transverse direction. The lower end of the upper pressure frame (6) protrudes from the lower surface of the upper plate (1). The lower right surface of the upper plate (1) has an integrally formed ring pressure platform (7). The ring pressure platform (7) has a drip hole (4) at the middle. The upper surface of the lower plate (2) has grooves (9) at the middle and right. The bottom surface of the grooves (9) has a collection groove (10), a diversion groove (11), and a diversion groove. (12) The liquid collection tank (10) is located at the right end of the diversion tank (11) and is connected to each other. The diversion tank (12) connects the front edge and the rear edge of the diversion tank (11). The groove (9) is filled with a seepage layer (13). The test paper (3) is laid on the upper surface of the lower plate (2) and the upper surface of the seepage layer (13). The test paper (3) cooperates with the lower pressure frame. The upper surface of the upper plate (1) has some marking marks (5).

2. The rapid detection device for recombinant protein Eg FABP1 with a flow equalization structure according to claim 1, characterized in that: The upper surface of the lower plate (2) has a positioning ring (8) integrally formed on the left half. The test paper (3) is embedded in the positioning ring (8). The upper pressure frame (6) is fitted with the positioning ring (8) and presses the outer edge of the test paper (3).

3. The rapid detection device for recombinant protein Eg FABP1 with a flow equalization structure according to claim 2, characterized in that: The width of the test strip (3) is 1.25 to 1.3 times the width of the permeate layer (13).

4. The rapid detection device for recombinant protein Eg FABP1 with a flow equalization structure according to claim 1, characterized in that: The length of the front and rear ends of the diversion channel (12) is 0.75 to 0.8 times the width of the permeate layer (13).

5. The rapid detection device for recombinant protein Eg FABP1 with a flow equalization structure according to claim 3, characterized in that: The ring pressure platform (7) presses the right end of the permeate layer (13), and the drip hole (4) cooperates with the liquid collection tank (10).

6. The rapid detection device for recombinant protein Eg FABP1 with a flow equalization structure according to claim 5, characterized in that: The overlap length between the test paper (3) and the permeation layer (13) is one-half to two-thirds of the length of the test paper (3).

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