An antibody screening microplate washing device

Abstract

The utility model discloses an antibody screening microporous plate cleaning device, including the cleaning platform, the one side of cleaning platform top is installed for the abutting plate of the antibody screening microporous plate of waiting for cleaning position, the other side of cleaning platform top is installed with the clamping positioning assembly of cooperation with abutting plate, still be installed with the cleaning assembly for the antibody screening microporous plate cleaning of cleaning platform. The utility model discloses through the convenient positioning structure of abutting plate and swing clamp board cooperation, can fixed microporous plate fast and stably, avoids the uneven and damage problem of displacement when cleaning, and the positioning of convenient and the efficient cleaning greatly shorten operating time, improve work efficiency, reciprocating movement of the brush washing assembly and the flushing assembly with the help of electric cylinder, combine electric push rod, brush washing motor and flush pump, realize efficient and thorough rotation and flush and brush, effectively remove the residual in the micropore, ensure microporous plate cleanliness simultaneously, avoid the residual interference follow -up experiment, guarantee experiment accuracy and reliability.

Description

Technical Field

[0001] This utility model relates to the field of antibody screening microplate cleaning technology, and in particular to an antibody screening microplate cleaning device. Background Technology

[0002] In biomedical research and antibody-related detection, antibody screening microplates are commonly used experimental tools. Thorough cleaning of used antibody screening microplates is a crucial step in ensuring the accuracy and reliability of subsequent experiments.

[0003] In existing technologies, such as the integrated microplate cleaning and drying device disclosed in CN213349851U, although it has cleaning and drying functions, it has significant shortcomings in practical applications. This device is not convenient for positioning and fixing the antibody screening microplates to be cleaned. During the cleaning process, if the microplate cannot be stably positioned, it is prone to displacement, leading to uneven cleaning and potentially damaging the microplate, affecting subsequent experimental results. Moreover, due to the lack of an effective positioning and fixing mechanism, the placement and removal of microplates in automated cleaning processes are cumbersome, increasing the workload of operators and reducing work efficiency. Utility Model Content

[0004] The purpose of this invention is to provide a microplate cleaning device for antibody screening. Through a convenient positioning structure using a contact plate and a movable clamping plate, the microplate can be quickly and stably fixed, avoiding unevenness and damage caused by displacement during cleaning. The convenient positioning and efficient cleaning significantly shorten operation time and improve work efficiency. The electric cylinder drives the brushing and rinsing components to move back and forth, combined with an electric push rod, brushing motor, and rinsing pump, achieving efficient and thorough rotary brushing and rinsing. This effectively removes residues from the microwells while ensuring the cleanliness of the microplate, preventing residue interference with subsequent experiments, and guaranteeing experimental accuracy and reliability.

[0005] To achieve the above objectives, the main technical solutions adopted by this utility model include:

[0006] An antibody screening microplate washing device, comprising:

[0007] A cleaning station is provided, with an abutment plate installed on one side of the top of the cleaning station for positioning the antibody screening microplate to be cleaned, and a clamping and positioning assembly for cooperating with the abutment plate installed on the other side of the top of the cleaning station. A cleaning assembly for cleaning the antibody screening microplate is also installed on the cleaning station.

[0008] In the above-mentioned antibody screening microplate cleaning device, the clamping and positioning component includes a mounting base fixedly connected to the top of the cleaning table, and an adjustable movable clamping plate is provided on the side of the mounting base.

[0009] In the above-mentioned antibody screening microplate cleaning device, a threaded seat is fixedly connected to the mounting base, and a clamping bolt for adjusting the movable clamping plate is threadedly connected to the threaded seat. The end of the clamping bolt is rotatably connected to the side of the movable clamping plate through a bearing.

[0010] In the above-mentioned antibody screening microplate cleaning device, two symmetrically arranged limiting telescopic rods are fixedly connected to the side of the mounting base, and the other end of the limiting telescopic rods is fixedly connected to the side of the movable clamping plate.

[0011] In the above-mentioned antibody screening microplate cleaning device, a clamping pad is fixedly connected to the side of the movable clamping plate.

[0012] The antibody screening microplate cleaning device described above includes a cleaning assembly comprising a support base fixedly connected to the top of the cleaning table, a retractable and adjustable movable seat provided on the side of the support base, and a brushing assembly and a rinsing assembly for cleaning the antibody screening microplate sequentially mounted on the movable seat.

[0013] In the above-mentioned antibody screening microplate cleaning device, an electric cylinder for driving the moving seat is fixedly connected to the side of the support base, and the output end of the electric cylinder is fixedly connected to the side of the moving seat.

[0014] The antibody screening microplate cleaning device described above includes a brushing assembly comprising an electric push rod fixedly connected to the movable base, a brushing motor fixedly connected to the output end of the electric push rod, and a cleaning brush mounted on the output shaft of the brushing motor.

[0015] The antibody screening microplate cleaning device described above includes a rinsing assembly comprising a rinsing pump fixedly connected to the movable base, a connecting hose installed at the bottom of the rinsing pump, and a rinsing nozzle installed at the bottom of the connecting hose.

[0016] In the above-mentioned antibody screening microplate cleaning device, a positioning rod is fixedly connected to one end of the connecting hose near the rinsing nozzle, and the side of the positioning rod is fixedly connected to the side of the brushing motor.

[0017] This utility model has at least the following beneficial effects:

[0018] 1. This utility model realizes an antibody screening microplate cleaning device. Through the convenient positioning structure of the abutment plate and the movable clamping plate, the microplate can be quickly and stably fixed, avoiding unevenness and damage caused by displacement during cleaning. The convenient positioning and efficient cleaning greatly shorten the operation time and improve work efficiency. With the help of the electric cylinder to drive the brushing and rinsing components to move back and forth, combined with the electric push rod, brushing motor and rinsing pump, efficient and thorough rotational brushing and rinsing are achieved, effectively removing residues in the microwells, while ensuring the cleanliness of the microplate, avoiding residue interference with subsequent experiments, and ensuring the accuracy and reliability of the experiment.

[0019] 2. Convenient Positioning and Fixing: First, place one end of the antibody screening microplate to be cleaned against the side of the abutment plate. Then, rotate the clamping bolt. Under the action of the threaded seat, the movable clamping plate abuts against the other end of the antibody screening microplate, thus achieving convenient positioning of the microplate. This positioning method is simple to operate and can quickly and accurately fix the microplate, ensuring its stability during the cleaning process and avoiding uneven cleaning and microplate damage caused by displacement.

[0020] 3. High-efficiency cleaning: An electric cylinder drives the brushing and rinsing components on the moving base to reciprocate, achieving comprehensive cleaning of the microplate. The electric push rod of the brushing component moves the cleaning brush downwards to contact the antibody screening microplate, and then the brushing motor drives the cleaning brush to rotate, effectively rotating and brushing the microplate to remove residual substances from the microwells. Simultaneously, a rinsing pump delivers cleaning water, rinsing the antibody screening microplate through the rinsing nozzles to further ensure the cleanliness of the microplate. This cleaning method combines brushing and rinsing, enabling a more thorough removal of dirt and residue from the microplate and improving the cleaning effect. Attached Figure Description

[0021] The accompanying drawings, which are included to provide a further understanding of this application and form part of this application, illustrate exemplary embodiments and are used to explain this application, but do not constitute an undue limitation of this application. In the drawings:

[0022] Figure 1 This is a schematic diagram of the antibody screening microplate cleaning device of this utility model;

[0023] Figure 2 This is a schematic diagram of the clamping and positioning component in the antibody screening microplate cleaning device of this utility model;

[0024] Figure 3 This is a schematic diagram of the cleaning components in the antibody screening microplate cleaning device of this utility model;

[0025] Figure 4 This is a schematic diagram of the brushing component in the antibody screening microplate cleaning device of this utility model;

[0026] Figure 5 This is a schematic diagram of the rinsing component in the antibody screening microplate cleaning device of this utility model.

[0027] Explanation of icon numbers:

[0028] 1. Cleaning table; 2. Abutment plate; 3. Clamping and positioning assembly; 4. Cleaning assembly;

[0029] 301. Mounting base; 3011. Movable clamp;

[0030] 302, threaded seat; 3021, clamping bolt;

[0031] 303. Limiting telescopic rod;

[0032] 304. Clamping pad;

[0033] 401. Support base; 402. Electric cylinder;

[0034] 4011. Movable seat; 4012. Scrubbing assembly; 4013. Rinsing assembly;

[0035] 40121. Electric push rod; 40122. Brush motor; 40123. Cleaning brush;

[0036] 40131. Flushing pump; 40132. Connecting hose; 40133. Flushing nozzle; 40134. Positioning rod. Detailed Implementation

[0037] The following will describe in detail the implementation of this application with reference to the accompanying drawings and embodiments, so that the implementation process of how this application uses technical means to solve technical problems and achieve technical effects can be fully understood and implemented accordingly.

[0038] Please refer to Figures 1 to 5 As shown, an embodiment of the present invention provides an antibody screening microplate cleaning device, comprising: a cleaning platform 1, an abutment plate 2 for positioning the antibody screening microplate to be cleaned is installed on one side of the top of the cleaning platform 1, a clamping and positioning assembly 3 for cooperating with the abutment plate 2 is installed on the other side of the top of the cleaning platform 1, and a cleaning assembly 4 for cleaning the antibody screening microplate is also installed on the cleaning platform 1.

[0039] By adopting the above technical solution, the convenient positioning structure of the contact plate 2 and the movable clamping plate 3011 can quickly and stably fix the microporous plate, avoiding unevenness and damage caused by displacement during cleaning. The convenient positioning and efficient cleaning greatly shorten the operation time and improve work efficiency. With the help of the electric cylinder 402 to drive the brushing component 4012 and the rinsing component 4013 to move back and forth, combined with the electric push rod 40121, the brushing motor 40122 and the rinsing pump 40131, efficient and thorough rotational brushing and rinsing are achieved, effectively removing residues in the micropores, while ensuring the cleanliness of the microporous plate, avoiding residue interference with subsequent experiments, and ensuring the accuracy and reliability of the experiments.

[0040] In order to achieve initial positioning and support for the antibody screening microplate and provide a basic structure for subsequent clamping and adjustment, in this embodiment: the clamping and positioning component 3 includes a mounting base 301 fixedly connected to the top of the washing table 1, and an adjustable movable clamping plate 3011 is provided on the side of the mounting base 301.

[0041] To achieve precise adjustment of the movable clamping plate 3011 and thus stably clamp the antibody screening microplate, in this embodiment: a threaded seat 302 is fixedly connected to the mounting base 301, and a clamping bolt 3021 for adjusting the movable clamping plate 3011 is threaded onto the threaded seat 302. The end of the clamping bolt 3021 is rotatably connected to the side of the movable clamping plate 3011 via a bearing. By rotating the clamping bolt 3021, under the action of the thread on the threaded seat 302, the clamping bolt 3021 can push the movable clamping plate 3011 to move horizontally, realizing the clamping or loosening operation of the microplate. At the same time, the end of the clamping bolt 3021 is rotatably connected to the movable clamping plate 3011 via the bearing, ensuring that when the clamping bolt 3021 is rotated, the movable clamping plate 3011 will not rotate accordingly, but will only perform a linear movement in the horizontal direction, thus improving the stability and accuracy of clamping.

[0042] To ensure the stability of the movable clamping plate 3011 during movement and prevent it from shifting during movement, in this embodiment, two symmetrically arranged limiting telescopic rods 303 are fixedly connected to the side of the mounting base 301, and the other end of the limiting telescopic rod 303 is fixedly connected to the side of the movable clamping plate 3011. The limiting telescopic rod 303 plays a limiting and guiding role for the movable clamping plate 3011. When the clamping bolt 3021 pushes the movable clamping plate 3011 to move, the limiting telescopic rod 303 will extend and retract accordingly, ensuring that the movable clamping plate 3011 always moves along the predetermined direction, avoiding inaccurate clamping or damage to the micro-perforated plate caused by shifting.

[0043] In order to increase the friction between the movable clamping plate 3011 and the antibody screening microplate, improve the clamping firmness, and prevent scratching the microplate, in this embodiment, a clamping pad 304 is fixedly connected to the side of the movable clamping plate 3011.

[0044] To achieve thorough cleaning of the antibody screening microplate, a movable seat 4011 drives the brushing assembly 4012 and the rinsing assembly 4013 to reciprocate. In this embodiment, the cleaning assembly 4 includes a support base 401 fixedly connected to the top of the cleaning table 1. The side of the support base 401 is provided with a telescopically adjustable movable seat 4011. The brushing assembly 4012 and the rinsing assembly 4013 for cleaning the antibody screening microplate are sequentially installed on the movable seat 4011. An electric cylinder 402 for driving the movable seat 4011 is fixedly connected to the side of the support base 401, and the output end of the electric cylinder 402 is fixedly connected to the side of the movable seat 4011.

[0045] To achieve the washing function of the antibody screening microplate, in this embodiment: the washing assembly 4012 includes an electric push rod 40121 fixedly connected to the movable base 4011. A washing motor 40122 is fixedly connected to the output end of the electric push rod 40121. A cleaning brush 40123 is mounted on the output shaft of the washing motor 40122. The electric push rod 40121 can drive the washing motor 40122 and the cleaning brush 40123 to move up and down, thereby adjusting the distance between the cleaning brush 40123 and the microplate, ensuring that the cleaning brush 40123 can make close contact with the surface of the microplate. The washing motor 40122 drives the cleaning brush 40123 to rotate, washing the surface of the microplate and effectively removing residual substances in the micropores.

[0046] To achieve the rinsing function of the antibody screening microplate, a rinsing pump 40131 delivers cleaning water to a rinsing nozzle 40133 to rinse the microplate. In this embodiment, the rinsing assembly 4013 includes a rinsing pump 40131 fixedly connected to a movable base 4011. A connecting hose 40132 is installed at the bottom of the rinsing pump 40131, and a rinsing nozzle 40133 is installed at the bottom of the connecting hose 40132. The rinsing pump 40131 draws cleaning water from a water source and delivers it to the rinsing nozzle 40133 through the connecting hose 40132. The rinsing nozzle 40133 sprays the cleaning water onto the surface of the microplate at a certain pressure and angle to further remove residual dirt and impurities after brushing, thereby improving the cleaning effect.

[0047] To ensure the relative position between the rinsing nozzle 40133 and the brushing motor 40122 is stable, so that the rinsing and brushing operations can work together to improve cleaning efficiency and quality, in this embodiment: a positioning rod 40134 is fixedly connected to one end of the connecting hose 40132 near the rinsing nozzle 40133, and the side of the positioning rod 40134 is fixedly connected to the side of the brushing motor 40122.

[0048] The working principle of this invention is as follows: First, the antibody screening microplate to be cleaned is placed on the cleaning table 1, with one end abutting against the side of the abutment plate 2. Then, by rotating the clamping bolt 3021, under the action of the threaded seat 302, the clamping bolt 3021 pushes the movable clamping plate 3011 to move horizontally. At the same time, the limiting telescopic rod 303 ensures the stability of the movement of the movable clamping plate 3011, and the clamping pad 304 increases friction and prevents scratching the microplate, ultimately achieving stable clamping and positioning of the microplate. Subsequently, the electric cylinder 402 drives the moving seat 4011 to reciprocate on the side of the support seat 401, driving the brushing assembly 4012 and the rinsing assembly 4013 to move above the microplate. In the brushing assembly 4012, the electric push rod 40121 drives the brushing motor 40122 and the cleaning brush 40123 to move down to a suitable position. The brushing motor 40122 drives the cleaning brush 40123 to rotate and brush the microplate. In the rinsing assembly 4013, the rinsing pump 40131 delivers cleaning water to the rinsing nozzle 40133 through the connecting hose 40132. The rinsing nozzle 40133 rinses the microplate, and the positioning rod 40134 ensures that the rinsing nozzle 40133 and the brushing motor 40122 are relatively stable, realizing the coordinated operation of brushing and rinsing, thereby completing the comprehensive and efficient cleaning of the antibody screening microplate.

[0049] The foregoing description illustrates and describes several preferred embodiments of the present invention. However, as previously stated, it should be understood that the present invention is not limited to the forms disclosed herein and should not be construed as excluding other embodiments. It can be used in various other combinations, modifications, and environments, and can be altered within the scope of the present invention's conception through the foregoing teachings or related technical or knowledge. Any modifications and variations made by those skilled in the art that do not depart from the spirit and scope of the present invention should be within the protection scope of the appended claims.

Claims

1. A microplate cleaning device for antibody screening, comprising a cleaning table (1), characterized in that, A contact plate (2) for positioning the antibody screening microplate to be cleaned is installed on one side of the top of the cleaning station (1), and a clamping and positioning assembly (3) for cooperating with the contact plate (2) is installed on the other side of the top of the cleaning station (1). A cleaning assembly (4) for cleaning the antibody screening microplate is also installed on the cleaning station (1).

2. The antibody screening microplate cleaning device according to claim 1, characterized in that: The clamping and positioning assembly (3) includes a mounting base (301) fixedly connected to the top of the cleaning table (1), and an adjustable movable clamping plate (3011) is provided on the side of the mounting base (301).

3. The antibody screening microplate cleaning device according to claim 2, characterized in that: A threaded seat (302) is fixedly connected to the mounting base (301), and a clamping bolt (3021) for adjusting the movable clamping plate (3011) is threadedly connected to the threaded seat (302). The end of the clamping bolt (3021) is rotatably connected to the side of the movable clamping plate (3011) through a bearing.

4. The antibody screening microplate cleaning device according to claim 3, characterized in that: The mounting base (301) is also fixedly connected to two symmetrically arranged limiting telescopic rods (303), and the other end of the limiting telescopic rods (303) is fixedly connected to the side of the movable clamp (3011).

5. The antibody screening microplate cleaning device according to claim 4, characterized in that: The side of the movable clamping plate (3011) is fixedly connected with a clamping pad (304).

6. The antibody screening microplate cleaning device according to claim 5, characterized in that: The cleaning assembly (4) includes a support base (401) fixedly connected to the top of the cleaning table (1). The side of the support base (401) is provided with a telescopically adjustable movable seat (4011). A brushing assembly (4012) and a rinsing assembly (4013) for cleaning antibody screening microplates are installed sequentially on the movable seat (4011).

7. The antibody screening microplate cleaning device according to claim 6, characterized in that: An electric cylinder (402) for driving the movable seat (4011) is fixedly connected to the side of the support base (401), and the output end of the electric cylinder (402) is fixedly connected to the side of the movable seat (4011).

8. The antibody screening microplate cleaning device according to claim 7, characterized in that: The scrubbing assembly (4012) includes an electric push rod (40121) fixedly connected to the movable base (4011), a scrubbing motor (40122) fixedly connected to the output end of the electric push rod (40121), and a cleaning brush (40123) mounted on the output shaft of the scrubbing motor (40122).

9. The antibody screening microplate cleaning device according to claim 8, characterized in that: The flushing assembly (4013) includes a flushing pump (40131) fixedly connected to the movable base (4011), a connecting hose (40132) is installed at the bottom of the flushing pump (40131), and a flushing nozzle (40133) is installed at the bottom of the connecting hose (40132).

10. The antibody screening microplate cleaning device according to claim 9, characterized in that: A positioning rod (40134) is fixedly connected to one end of the connecting hose (40132) near the rinsing nozzle (40133), and the side of the positioning rod (40134) is fixedly connected to the side of the brush motor (40122).

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