A switch cover device and PCR analysis apparatus

Abstract

This utility model relates to the field of medical device technology, specifically disclosing a cap-switching device and a PCR analysis device, including a carrier plate, a clamping mechanism, and a vertical moving mechanism. The clamping mechanism includes a support bracket, a first driving component, a pressing component, and a snap-fit ​​component. The support bracket is movably mounted on the carrier plate along the Z-direction, and the first driving component and the snap-fit ​​component are both mounted on the support bracket. The driving end of the first driving component is connected to the pressing component. The vertical moving mechanism is mounted on the carrier plate, and its driving end is connected to the support bracket. The cap-switching device of this utility model enables the opening and closing of reaction consumables, avoiding the difficulty of opening and closing caps caused by tilting of the tube caps. It is not only highly efficient but also prevents deformation of the tube body or the tube caps, thereby reducing the probability of errors and improving the accuracy and reliability of the tube caps being mounted on the tube body. It also reduces labor costs and the risk of contamination.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to a cover opening and closing device and a PCR analysis device. Background Technology

[0002] PCR (Polymerase Chain Reaction) is a molecular biology technique that rapidly amplifies specific DNA fragments in vitro. By mimicking the natural DNA replication process, it utilizes temperature cycling and DNA polymerase to achieve exponential amplification of the target sequence and is widely used in various fields of biology and medicine.

[0003] Currently, in PCR experiments, reagents are typically dispensed into PCR multiplex tubes. In existing technology, PCR multiplex tubes are mostly opened and closed manually. This method is not only time-consuming and labor-intensive but also affects experimental efficiency. Furthermore, manually opening the tubes can easily deform the tubes or caps, thus affecting the experimental results. Additionally, manual operation increases the risk of liquid splashing, raising the risk of contamination. Utility Model Content

[0004] The purpose of this invention is to provide a cap-opening device and a PCR analysis device to solve the problem that manual cap opening and closing affects the efficiency of experimental operations in the prior art, prevent tube deformation or cap deformation during cap opening, which would affect experimental results, prevent liquid splashing, and avoid contamination of experimental equipment.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] On one hand, this utility model provides a cover-opening device for opening or closing a reaction consumable, wherein the reaction consumable includes a plurality of tubes arranged side by side and a series of tube caps covering the plurality of tubes, and the cover-opening device includes a carrier plate and:

[0007] A clamping mechanism includes a support bracket, a first driving assembly, a pressing assembly, and a snap-fit ​​component. The support bracket is movably mounted on the carrier plate along the Z-direction. The first driving assembly and the snap-fit ​​component are both mounted on the support bracket. The driving end of the first driving assembly is connected to the pressing assembly and is used to drive the pressing assembly to move closer to or away from the snap-fit ​​component along the Z-direction. The snap-fit ​​component can be inserted into the intermediate hole between the pipe cap and two adjacent pipe bodies. The orthographic projection of the pressing assembly along the Z-direction coincides entirely or partially with the snap-fit ​​component, and a gap is provided between the pressing assembly and the snap-fit ​​component along the Z-direction to accommodate the pipe cap.

[0008] A vertical moving mechanism is provided on the carrier plate; the driving end of the vertical moving mechanism is connected to the bearing bracket and is used to drive the bearing bracket to move along the Z direction.

[0009] As an optional embodiment of the aforementioned switch cover device, the pressing assembly includes a guide block, an elastic element, a guide rod, and a pressure plate. The guide block is located at the driving end of the first driving assembly. One end of the guide rod is movably disposed on the guide block along the Z direction, and the other end of the guide rod is connected to the pressure plate. The elastic element is sleeved on the guide rod and located between the pressure plate and the guide block. The pressure plate can press the manifold cover tightly to fit the snap-fit ​​component.

[0010] As an alternative to the above-mentioned switch cover device, the support bracket is provided with a slide rail, the guide block is connected to a slider, and the slider is movable on the slide rail along the Z direction.

[0011] As an alternative to the above-mentioned switch cover device, the pressing assembly further includes a first position sensor, which is disposed on the support bracket and is used to sense the position of the guide block.

[0012] As an alternative to the aforementioned switch cover device, the snap-fit ​​component includes a mounting plate and a claw connected to the mounting plate, the mounting plate being disposed on the support bracket; the mounting plate and the claw are arranged in an L-shaped structure.

[0013] As an alternative to the above-mentioned switch cover device, the switch cover device further includes a second position sensor, which is disposed on the carrier plate and is used to sense the position of the pipe cover.

[0014] As an optional embodiment of the above-mentioned cover opening and closing device, the cover opening and closing device further includes a loading mechanism, which includes a loading frame, a second driving component, a first clamp, and a second clamp. The second driving component is disposed on the loading frame, and the tube body can be placed on the loading frame. The driving end of the second driving component is connected to the first clamp and the second clamp, and is used to drive the first clamp and the second clamp to move closer to each other in a direction perpendicular to the Z direction to clamp the tube body, or to move away from each other to release the tube body. The first clamp has a first limiting groove, and the second clamp has a second limiting groove, with the first limiting groove and the second limiting groove being arranged opposite to each other.

[0015] As an optional solution for the above-mentioned switch cover device, the loading mechanism further includes a limiting frame, which is disposed on the loading frame; the limiting frame has a limiting slot, in which the pipe cover can be embedded; a plurality of chamfered portions are provided at intervals on one side of the limiting frame, and the plurality of chamfered portions are located in the limiting slot to abut and limit the pipe cover; the other side of the limiting frame has a through groove that penetrates and connects to the limiting slot in a direction perpendicular to the Z direction.

[0016] As an alternative to the above-mentioned switch cover device, the switch cover device further includes a horizontal moving mechanism, the driving end of which is connected to the carrier plate and is used to drive the carrier plate to move in a direction perpendicular to the Z direction.

[0017] On the other hand, this utility model also provides a PCR analysis device, including the opening and closing cover device as described above.

[0018] The beneficial effects of this utility model are as follows:

[0019] The cover opening and closing device includes a carrier plate, a clamping mechanism, and a vertical moving mechanism. The clamping mechanism includes a support bracket, a first driving assembly, a pressing assembly, and a snap-fit ​​component. The support bracket is movably mounted on the carrier plate along the Z-direction. The first driving assembly and the snap-fit ​​component are both mounted on the support bracket. The driving end of the first driving assembly is connected to the pressing assembly, driving the pressing assembly to move closer to or away from the snap-fit ​​component along the Z-direction. The snap-fit ​​component can be inserted into the intermediate hole between the pipe cover and two adjacent pipe bodies. The orthographic projection of the pressing assembly along the Z-direction coincides entirely or partially with the snap-fit ​​component, and a gap is provided between the pressing assembly and the snap-fit ​​component along the Z-direction to accommodate the pipe cover. Thus, as the pressing assembly moves closer to or away from the snap-fit ​​component, the clamping mechanism can grasp or release the pipe cover. Simultaneously, The vertical moving mechanism is located on the carrier plate, and its drive end is connected to the support bracket. It drives the support bracket to move along the Z direction, thereby adjusting the position of the snap-fit ​​component and the crimping component by moving the carrier plate through the vertical moving mechanism. This facilitates the clamping of the comb tube cap by the crimping component and the snap-fit ​​component. When the clamping mechanism grabs the comb tube cap, the vertical moving mechanism moves the carrier plate to open or close the reaction consumables. During the opening process, the snap-fit ​​component and the crimping component can hold the tube cap in place, causing the tube cap to move away from the tube body synchronously, preventing the tube cap from slipping or popping out and contaminating the experiment. During the closing process, the first drive component can drive the crimping component to press down on the comb tube cap, thereby improving the reliability of the closing. This cap-opening device enables the opening and closing of reaction consumables. Through the cooperation of the crimping assembly and the snap-fit ​​component, it ensures that the caps on the tubes are level during the opening and closing process, avoiding difficulties caused by tilting the caps. This not only increases efficiency but also prevents deformation of the tubes or caps, reducing the probability of errors and improving the accuracy and reliability of cap placement on the tubes. It also reduces labor costs and the risk of contamination. The crimping assembly is independently driven by the first drive assembly, and its stroke is independently controlled. The vertical distance between the crimping assembly and the snap-fit ​​component can be automatically adjusted to accommodate caps of different heights and specifications. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the structure of the switch cover device provided in an embodiment of the present utility model;

[0021] Figure 2 This is a schematic diagram of the clamping mechanism provided in an embodiment of the present utility model;

[0022] Figure 3 A cross-sectional view of the clamping mechanism provided in an embodiment of this utility model;

[0023] Figure 4 This is a schematic diagram of the loading mechanism provided in an embodiment of the present utility model;

[0024] Figure 5 for Figure 4A magnified view of a portion of point A in the middle.

[0025] In the picture:

[0026] 1. Carrier plate; 2. Clamping mechanism; 21. Bearing bracket; 211. Slide rail; 22. First drive assembly; 23. Pressing assembly; 231. Guide block; 232. Elastic element; 233. Guide rod; 234. Pressure plate; 235. Slider; 236. First position sensor; 24. Snap-fit ​​component; 241. Mounting plate; 242. Claw; 3. Vertical moving mechanism; 4. Second position sensor; 5. Loading mechanism; 51. Loading frame; 52. Second drive assembly; 53. First clamp; 531. First limiting groove; 54. Second clamp; 541. Second limiting groove; 55. Limiting frame; 551. Limiting slot; 552. Chamfered part; 6. Reaction consumables; 61. Tube body; 62. Connecting tube cap. Detailed Implementation

[0027] The technical solution of this utility model will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0028] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this utility model and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance. The terms "first position" and "second position" refer to two different positions. Moreover, "above," "on top of," and "over" the first feature in relation to the second feature includes the first feature directly above and diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "under," and "below" the first feature in relation to the second feature includes the first feature directly below and diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0029] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0030] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0031] like Figures 1-5 As shown, this embodiment provides a cover opening and closing device for opening or closing the reaction consumable 6. The reaction consumable 6 includes a plurality of tube bodies 61 arranged side by side and a row of tube covers 62 covering the plurality of tube bodies 61.

[0032] The switch cover device includes a carrier plate 1, a clamping mechanism 2, and a vertical moving mechanism 3. The clamping mechanism 2 includes a support bracket 21, a first drive assembly 22, a pressing assembly 23, and a latching member 24. The support bracket 21 is movably mounted on the carrier plate 1 along the Z-direction. The first drive assembly 22 and the latching member 24 are both mounted on the support bracket 21. The drive end of the first drive assembly 22 is connected to the pressing assembly 23, driving the pressing assembly 23 to move closer to or away from the latching member 24 along the Z-direction. The latching member 24 can be inserted into the intermediate hole between the pipe cover 62 and two adjacent pipe bodies 61. The orthographic projection of the pressing assembly 23 along the Z-direction coincides entirely or partially with the latching member 24, and a gap exists between the pressing assembly 23 and the latching member 24 along the Z-direction to accommodate the pipe cover 62. Thus, as the pressing assembly 23 moves closer to or away from the latching member 24, the clamping mechanism 2 can grasp or release the pipe cover 62. Optionally, the first drive assembly 22 is a lead screw motor.

[0033] Meanwhile, the vertical moving mechanism 3 is located on the carrier plate 1, and the driving end of the vertical moving mechanism 3 is connected to the bearing bracket 21 to drive the bearing bracket 21 to move along the Z direction. Thus, by moving the carrier plate 1 through the vertical moving mechanism 3, the position of the snap-fit ​​component 24 and the crimping component 23 can be adjusted, which facilitates the clamping of the connecting tube cap 62 by the crimping component 23 and the snap-fit ​​component 24. When the clamping mechanism 2 grabs the connecting tube cap 62, the vertical moving mechanism 3 can move the carrier plate 1 to realize the opening or closing of the reaction consumable 6. During the opening process, the snap-fit ​​component 24 and the crimping component 23 can clamp the tube cap 62 and drive the tube cap 62 away from the tube body 61 at the same time, avoiding the tube cap 62 from slipping or popping out and contaminating the experiment. During the closing process, the first driving component 22 can drive the crimping component 23 to press down the connecting tube cap 62, thereby improving the reliability of closing the cap.

[0034] This cap-opening device enables the opening and closing of the reaction consumable 6. Through the cooperation of the crimping assembly 23 and the snap-fit ​​component 24, it ensures the horizontal position of the tube cap 62 during the opening and closing process on several tube bodies 61, avoiding difficulties caused by tilting the tube cap 62. This not only increases efficiency but also prevents deformation of the tube body 61 or the tube cap 62, thereby reducing the probability of errors and improving the accuracy and reliability of the tube cap 62 on the tube body 61. It also reduces labor costs and the risk of contamination. The crimping assembly 23 is independently driven by the first drive assembly 22, and its stroke is independently controlled. The vertical distance between the crimping assembly 23 and the snap-fit ​​component 24 can be automatically adjusted to accommodate tube caps 62 of different heights and specifications. Optionally, the reaction consumable 6 is a PCR multi-tube. Of course, the reaction consumable 6 can also be other types of consumables; this embodiment does not impose specific limitations.

[0035] Specifically, the vertical moving mechanism 3 includes a vertical drive motor, a transmission belt, and a linear lead screw. Both the vertical drive motor and the linear lead screw are mounted on the carrier plate 1. The drive end of the vertical drive motor is connected to the linear lead screw via the transmission belt. The bearing bracket 21 is connected to the drive end of the linear lead screw. Thus, the height of the clamping mechanism 2 can be adjusted and controlled by the drive of the vertical drive motor.

[0036] like Figure 2 and Figure 3As shown, the crimping assembly 23 includes a guide block 231, an elastic element 232, a guide rod 233, and a pressure plate 234. The guide block 231 is located at the driving end of the first driving assembly 22, so that the guide block 231 can move along the Z direction under the drive of the first driving assembly 22. One end of the guide rod 233 is movably located on the guide block 231 along the Z direction, and the other end of the guide rod 233 is connected to the pressure plate 234. The elastic element 232 is sleeved on the guide rod 233 and located between the pressure plate 234 and the guide block 231. The pressure plate 234 can press the manhole cover 62. The clamping assembly 23 and the snap-fit ​​component 24 are pressed together to clamp the manifold cover 62. During the process of the guide block 231 driving the pressure plate 234 to press the manifold cover 62, the guide rod 233, in conjunction with the elastic element 232, can provide elastic buffering for the pressure plate 234 to press the manifold cover 62, thereby preventing the pressure plate 234 from rubbing against the consumable material 6, which would increase costs. At the same time, under the drive of the first drive assembly 22, the guide block 231 can directly abut against the pressure plate 234, thereby increasing the clamping force of the pressure plate 234 on the manifold cover 62. Optionally, a linear bearing is provided inside the guide block 231, and the guide rod 233 is movably disposed in the guide block 231 through the linear bearing.

[0037] Specifically, the support bracket 21 is provided with a slide rail 211, and the guide block 231 is connected to a slider 235. The slider 235 is movable along the Z direction on the slide rail 211. Thus, the arrangement of the slider 235 and the slide rail 211 can improve the stability and reliability of the movement of the guide block 231. At the same time, the pressing assembly 23 also includes a first position sensor 236, which is provided on the support bracket 21 to sense the position of the guide block 231, so as to avoid the guide block 231 descending too far and causing the pressure plate 234 to press the ring of the consumable 6.

[0038] Furthermore, the latching component 24 includes a mounting plate 241 and latching claws 242 connected to the mounting plate 241. The mounting plate 241 is disposed on the support bracket 21. The mounting plate 241 and the latching claws 242 are arranged in an L-shape. Thus, during the opening of the reaction consumable 6, the latching claws 242 of the latching component 24 can first insert into the intermediate hole between the tube cap 62 and two adjacent tube bodies 61. Then, the first driving component 22 drives the pressing component 23 to press down, thereby clamping the tube cap 62 and ensuring that the tube cap 62 is stable and will not detach. Then, during the process of the vertical moving component mechanism driving the support bracket 21 to rise, the latching claws 242 can hook up the tube cap 62 to realize the opening of the reaction consumable 6. Optionally, a plurality of latching claws 242 are provided, and the plurality of latching claws 242 are spaced apart along a direction perpendicular to the Z direction. The plurality of latching claws 242 can be inserted into a plurality of intermediate holes, thereby ensuring a stable clamping of the tube cap 62.

[0039] like Figure 1As shown, the cover opening and closing device also includes a second position sensor 4, which is located on the carrier plate 1 and is used to sense the position of the pipe cover 62. The second position sensor 4 can ensure that the crimping assembly 23 and the snap-fit ​​member 24 accurately clamp the pipe cover 62, avoiding gaps or misalignment that would affect the subsequent closing of the cover.

[0040] like Figure 4 and Figure 5 As shown, the opening and closing device also includes a loading mechanism 5, which includes a loading frame 51, a second driving assembly 52, a first clamp 53, and a second clamp 54. The second driving assembly 52 is disposed on the loading frame 51, and the tube body 61 can be placed on the loading frame 51. The driving end of the second driving assembly 52 is connected to the first clamp 53 and the second clamp 54, and is used to drive the first clamp 53 and the second clamp 54 to move closer to each other in a direction perpendicular to the Z direction to clamp the tube body 61, or to move away from each other to release the tube body 61, thereby realizing the gripping or release of the tube body 61 of the reaction consumable 6. This process is simple to operate, the installation or removal of the reaction consumable 6 is relatively easy, and it can effectively improve efficiency. The first clamp 53 has a first limiting groove 531, and the second clamp 54 has a second limiting groove 541. The first limiting groove 531 and the second limiting groove 541 are arranged opposite to each other, so that the first limiting groove 531 and the second limiting groove 541 can clamp the tube body 61 from both sides, thereby improving the accuracy of the position of the reaction consumable 6 on the loading mechanism 5. Optionally, there are multiple first limiting grooves 531 and multiple second limiting grooves 541, and the multiple first limiting grooves 531 and multiple second limiting grooves 541 are arranged one-to-one to achieve synchronous limiting and clamping of multiple tube bodies 61.

[0041] Specifically, the second drive assembly 52 includes a second drive motor, a second transmission belt, and a second bidirectional lead screw. Both the second drive motor and the second bidirectional lead screw are mounted on the loading frame 51. The drive end of the second drive motor is connected to the second bidirectional lead screw via the second transmission belt. The first clamp 53 and the second clamp 54 are respectively connected to the two drive ends of the second bidirectional lead screw. Thus, the first clamp and the second clamp 54 are controlled to move closer to or further away from each other by the drive of the second drive motor.

[0042] Furthermore, the loading mechanism 5 also includes a limiting frame 55, which is disposed on the loading frame 51. The limiting frame 55 has a limiting slot 551, into which the pipe cover 62 can be embedded. The limiting slot 551 limits the position of the pipe cover 62, ensuring that the pipe cover 62 aligns with several pipe bodies 61 during opening and closing. A plurality of chamfered portions 552 are spaced apart on one side of the limiting frame 55, and these chamfered portions 552 are located within the limiting slot 551 for... The limiting frame 55 has a through groove on the other side of the limiting bracket 55, which is perpendicular to the Z-direction and connects to the limiting slot 551. The chamfered portion 552 prevents incorrect installation of the reaction consumable 6 on the loading mechanism 5, avoiding incorrect installation of the reaction consumable 6 and its impact on subsequent tests. Furthermore, during the clamping and gripping of the connecting tube cover 62, the through groove avoids the locking member 24, facilitating its insertion into the intermediate hole between the connecting tube cover 62 and two adjacent tube bodies 61. Specifically, by providing several chamfered portions 552, different models of reaction consumable 6 can be accommodated; that is, when two chamfered portions 552 are provided, the reaction consumable 6 can be one eight-tube or two four-tube units.

[0043] Furthermore, the switch cover also includes a horizontal moving mechanism. The driving end of the horizontal moving mechanism is connected to the carrier plate 1 and is used to drive the carrier plate 1 to move in a direction perpendicular to the Z direction. This allows for adjustment of the position of the clamping mechanism 2 in the direction perpendicular to the Z direction, making it easier to align the clamping mechanism 2 with the pipe cover 62. It also makes it easier for the snap-fit ​​part 24 to be inserted into the intermediate hole between the pipe cover 62 and the two adjacent pipe bodies 61 in a direction perpendicular to the Z direction.

[0044] This embodiment also provides a PCR analysis device, including the opening and closing device described above. By using the opening and closing device described above, the PCR analysis device realizes the opening and closing of the reaction consumable 6. Through the cooperation of the crimping component 23 and the snap-fit ​​component 24, it can ensure that the tube cap 62 is horizontal during the opening or closing process on several tube bodies 61, avoiding the difficulty of opening and closing the tube cap caused by the tilt of the tube cap 62. It is not only efficient, but also does not cause deformation of the tube body 61 or the tube cap 62, thereby reducing the probability of errors and improving the accuracy and reliability of the tube cap 62 being placed on the tube body 61. At the same time, it also reduces labor costs and the risk of contamination.

[0045] Obviously, the above embodiments of this utility model are merely examples for clearly illustrating the present utility model, and are not intended to limit the implementation of the present utility model. Those skilled in the art can make other variations or modifications based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this utility model should be included within the protection scope of the claims of this utility model.

Claims

1. A cover opening and closing device for opening or closing a reaction consumable (6), the reaction consumable (6) comprising a plurality of tubes (61) arranged side by side and a series of tube caps (62) covering the plurality of tubes (61), characterized in that, The opening and closing cover device includes a carrier plate (1) and: The clamping mechanism (2) includes a support bracket (21), a first driving component (22), a pressing component (23), and a snap-fit ​​component (24). The support bracket (21) is movably disposed on the carrier plate (1) along the Z direction. The first driving component (22) and the snap-fit ​​component (24) are both disposed on the support bracket (21). The driving end of the first driving component (22) is connected to the pressing component (23) and is used to drive the pressing component (23) to move closer to or away from the snap-fit ​​component (24) along the Z direction. The snap-fit ​​component (24) can be inserted into the intermediate hole between the pipe cap (62) and two adjacent pipe bodies (61). The orthographic projection of the pressing component (23) along the Z direction coincides with all or part of the snap-fit ​​component (24). The pressing component (23) and the snap-fit ​​component (24) are provided with a gap along the Z direction to accommodate the pipe cap (62). A vertical moving mechanism (3) is provided on the carrier plate (1); the driving end of the vertical moving mechanism (3) is connected to the bearing bracket (21) and is used to drive the bearing bracket (21) to move along the Z direction.

2. The opening and closing cover device according to claim 1, characterized in that, The crimping assembly (23) includes a guide block (231), an elastic element (232), a guide rod (233), and a pressure plate (234). The guide block (231) is located at the driving end of the first driving assembly (22). One end of the guide rod (233) is movably located on the guide block (231) along the Z direction, and the other end of the guide rod (233) is connected to the pressure plate (234). The elastic element (232) is sleeved on the guide rod (233) and located between the pressure plate (234) and the guide block (231). The pressure plate (234) can press the manifold cap (62) tightly to fit the snap-fit ​​member (24).

3. The opening and closing cover device according to claim 2, characterized in that, The support bracket (21) is provided with a slide rail (211), and the guide block (231) is connected to a slider (235). The slider (235) is movable on the slide rail (211) along the Z direction.

4. The opening and closing cover device according to claim 2, characterized in that, The crimping assembly (23) further includes a first position sensor (236), which is located on the support bracket (21) and is used to sense the position of the guide block (231).

5. The opening and closing cover device according to claim 1, characterized in that, The snap-fit ​​component (24) includes a mounting plate (241) and a claw (242) connected to the mounting plate (241). The mounting plate (241) is disposed on the support bracket (21). The mounting plate (241) and the claw (242) are arranged in an L-shape.

6. The opening and closing cover device according to claim 1, characterized in that, The switch cover device also includes a second position sensor (4), which is located on the carrier plate (1) and is used to sense the position of the pipe cover (62).

7. The opening and closing cover device according to claim 1, characterized in that, The opening and closing device further includes a loading mechanism (5), which includes a loading frame (51), a second driving component (52), a first clamp (53), and a second clamp (54). The second driving component (52) is disposed on the loading frame (51), and the tube body (61) can be placed on the loading frame (51). The driving end of the second driving component (52) is connected to the first clamp (53) and the second clamp (54) to drive the first clamp (53) and the second clamp (54) to move closer to each other in a direction perpendicular to the Z direction to clamp the tube body (61), or to move away from each other to release the tube body (61). The first clamp (53) is provided with a first limiting groove (531), and the second clamp (54) is provided with a second limiting groove (541). The first limiting groove (531) and the second limiting groove (541) are arranged opposite to each other.

8. The opening and closing cover device according to claim 7, characterized in that, The loading mechanism (5) further includes a limiting frame (55), which is disposed on the loading frame (51); the limiting frame (55) has a limiting slot (551), and the connecting pipe cover (62) can be embedded in the limiting slot (551); a plurality of chamfered portions (552) are provided at intervals on one side of the limiting frame (55), and the plurality of chamfered portions (552) are located in the limiting slot (551) for abutting and limiting the connecting pipe cover (62); the other side of the limiting frame (55) has a through groove that penetrates and connects to the limiting slot (551) in a direction perpendicular to the Z direction.

9. The opening and closing cover device according to any one of claims 1 to 8, characterized in that, The switch cover also includes a horizontal moving mechanism, the driving end of which is connected to the carrier plate (1) and is used to drive the carrier plate (1) to move in a direction perpendicular to the Z direction.

10. A PCR analysis device, characterized in that, Includes the cover opening and closing device as described in any one of claims 1 to 9.

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