Non-carcinogenic anti-infective composite hernia repair patch

Abstract

The utility model discloses a kind of infection-resistant composite hernia repair patches without carcinogenicity, including mesh polypropylene fiber sheet, the upper and lower two sides of mesh polypropylene fiber sheet are equipped with mesh polyglycolic acid fiber sheet, the mesh polyglycolic acid fiber sheet is connected by adhesive with mesh polypropylene fiber sheet, the mesh polypropylene fiber sheet is woven from monofilament structure.This infection-resistant composite hernia repair patch without carcinogenicity, through the cooperation between mesh polypropylene fiber sheet, mesh polyglycolic acid fiber sheet, adhesive, monofilament structure, polypropylene fiber, groove, slow-release capsule and antibacterial layer, the compatibility of patch and human tissue can be improved, and the antibacterial layer has good antibacterial performance, with the slow-release antibacterial and infection-resistant effect of slow-release capsule, the patch structure can be relatively long in antibacterial and infection-resistant effect in vivo, is not easy to cause infection and inflammatory response and can form abscess cavity or sinus.

Description

Technical Field

[0001] This utility model relates to the field of hernia repair patch technology, specifically a non-carcinogenic, anti-infective composite hernia repair patch. Background Technology

[0002] Hernia repair patches have been widely used in tension-free hernia repair surgery. The surgical technique is mature, and there is considerable professional academic exchange, leading to the rapid development of this type of surgery. In recent years, with the rapid development of materials science, various hernia repair materials have been widely used in clinical practice. Polypropylene mesh (Marlex, PP): woven from polypropylene fibers, it has a single-layer mesh structure and is currently the preferred material for repairing abdominal wall defects.

[0003] To reduce the chance of postoperative infection in patients, some publicly available technologies for hernia repair patches, such as utility model patents with authorized public accounts: CN204618943U, CN213250041U, and CN221534215U, can achieve a certain antibacterial and anti-infective effect by setting an antibacterial coating. However, the effective duration of antibacterial and anti-infective effects is relatively short, and the antibacterial and anti-infective effects cannot be sustained in the body. If the patch has poor biocompatibility with subsequent tissues, it is easy to cause infection and inflammatory reactions, and may form abscesses or sinuses. Utility Model Content

[0004] The purpose of this invention is to provide a non-carcinogenic, anti-infective composite hernia repair patch to address the issues raised in the background art. Although an antibacterial coating can be applied to the hernia repair patch to achieve a certain antibacterial and anti-infective effect, the effective duration of the antibacterial and anti-infective effect is relatively short, and the antibacterial and anti-infective effect cannot be sustained in vivo. If the patch has poor biocompatibility with subsequent tissues, it can easily cause infection and inflammatory reactions and may lead to abscesses or sinus tracts.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a non-carcinogenic, anti-infective composite hernia repair patch, comprising a mesh polypropylene fiber sheet, wherein mesh polyhydroxyacetic acid fiber sheets are provided on both the upper and lower surfaces of the mesh polypropylene fiber sheet, the mesh polyhydroxyacetic acid fiber sheets are connected to the mesh polypropylene fiber sheet by adhesive, the mesh polypropylene fiber sheet is woven from a monofilament structure, the monofilament structure includes polypropylene fiber filaments, grooves, sustained-release capsules and antibacterial layers, the outer side of the polypropylene fiber filaments is provided with multiple grooves, the inside of the grooves is provided with sustained-release capsules, and the outer side of both the sustained-release capsules and the polypropylene fiber filaments is provided with antibacterial layers.

[0006] Compared with the prior art, the beneficial effects of this utility model are: the non-carcinogenic, anti-infective composite hernia repair patch has the following advantages over traditional technology:

[0007] Through the combination of mesh polypropylene fiber sheets, mesh polyglycolic acid fiber sheets, adhesive, monofilament structure, polypropylene fiber filaments, grooves, sustained-release capsules, and antibacterial layers, the patch structure is applied in hernia repair surgery after being placed in the patient's body. Because both the mesh polypropylene fiber sheets and the mesh polyglycolic acid fiber sheets are mesh structures, they can facilitate the growth and passage of fibrous tissue and are easily infiltrated by connective tissue, enabling early integration with the tissue. Combined with the biodegradable and absorbable function of the mesh polyglycolic acid fiber sheets, the compatibility of the patch with human tissue is improved. The antibacterial layer has good antibacterial properties, and combined with the sustained-release capsule's sustained-release antibacterial and anti-infective effect, the patch structure can maintain an antibacterial and anti-infective effect in the body for a relatively long time, making it less likely to cause infection and inflammatory reactions and form abscesses or sinuses. Attached Figure Description

[0008] The above and other features, advantages, and aspects of the embodiments of this disclosure will become more apparent from the accompanying drawings and the following detailed description. Throughout the drawings, the same or similar reference numerals denote the same or similar elements. It should be understood that the drawings are schematic, and the originals and elements are not necessarily drawn to scale.

[0009] Figure 1 This is a schematic diagram of the structure of this utility model;

[0010] Figure 2 for Figure 1 Cross-sectional view of a monofilament structure.

[0011] In the diagram: 1. Mesh polypropylene fiber sheet, 2. Mesh polyglycolic acid fiber sheet, 3. Viscose, 4. Monofilament structure, 5. Polypropylene fiber filament, 6. Groove, 7. Sustained-release capsule, 8. Antibacterial layer. Detailed Implementation

[0012] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0013] Although an antibacterial coating can be applied to the hernia repair patch to provide some antibacterial and anti-infective effects, the duration of the antibacterial and anti-infective effect is relatively short, and the antibacterial and anti-infective effect cannot be sustained in the body. If the patch has poor biocompatibility with subsequent tissues, it can easily cause infection and inflammatory reactions and may form abscesses or sinus tracts.

[0014] In view of this, the present invention provides a non-carcinogenic, anti-infective composite hernia repair patch. Through the combination of a mesh polypropylene fiber sheet, a mesh polyglycolic acid fiber sheet, adhesive, a monofilament structure, polypropylene fiber filaments, grooves, a sustained-release capsule, and an antibacterial layer, the patch structure, after being placed in the patient's body during hernia repair surgery, benefits from the mesh structure of both the mesh polypropylene fiber sheet and the mesh polyglycolic acid fiber sheet. This facilitates the growth and passage of fibrous tissue and allows for easy infiltration by connective tissue, enabling early integration with the tissue. Combined with the biodegradable and absorbable function of the mesh polyglycolic acid fiber sheet, the compatibility of the patch with human tissue is improved. The antibacterial layer has excellent antibacterial properties, and combined with the sustained-release capsule's sustained-release antibacterial and anti-infective effect, the patch structure maintains a relatively long-lasting antibacterial and anti-infective effect in the body, reducing the likelihood of infection and inflammatory reactions and the formation of abscesses or sinus tracts.

[0015] Please see Figure 1-2 This utility model provides a technical solution: a non-carcinogenic, anti-infective composite hernia repair patch, comprising a mesh polypropylene fiber sheet 1, with mesh polyhydroxyacetic acid fiber sheets 2 on both the upper and lower surfaces of the mesh polypropylene fiber sheet 1, the mesh polyhydroxyacetic acid fiber sheets 2 being connected to the mesh polypropylene fiber sheet 1 by adhesive 3, the mesh polypropylene fiber sheet 1 being woven from a monofilament structure 4, the monofilament structure 4 including polypropylene fiber filaments 5, grooves 6, sustained-release capsules 7, and an antibacterial layer 8, the outer side of the polypropylene fiber filaments 5 having multiple grooves 6, the inner side of the grooves 6 having sustained-release capsules 7, and the outer side of both the sustained-release capsules 7 and the polypropylene fiber filaments 5 having an antibacterial layer 8.

[0016] In the specific implementation process, it is worth noting that both polypropylene fiber and polyglycolic acid fiber are widely used in the field of hernia repair. They are non-carcinogenic and represent a relatively good hernia repair structure. The mesh polyglycolic acid fiber sheet 2 is slowly degradable and absorbable in the body, aiming to reduce the amount of foreign matter (polypropylene). The adhesive 3 is a collagen glue, a medical adhesive made from collagen extracted from animal skin and bones, possessing good biocompatibility and biodegradability. This glue can be used in surgery, repair, and filling. The polypropylene fiber filament 5 is produced by spinning primary fibers using a screw extruder. During spinning, the spinneret (head) has a cross-shaped spinneret orifice, allowing the groove 6 to be positioned on the outside of the polypropylene fiber filament 5 after spinning. Then, the sustained-release capsule 7 can be placed inside the groove 6. The sustained-release capsule 7 is a microcapsule, or a type of microcapsule, referring to the shell of a solid or liquid drug (core or fill material). Drug-loaded microcapsules are drug reservoirs encapsulated in polymeric materials. The drugs encapsulated within these microcapsules can be released at specific sites and media, exhibiting different release characteristics such as sustained release, controlled release, or targeted release. Specifically, these are drug-loaded microcapsules containing antibacterial substances. The encapsulation material used to prepare these microcapsules should possess stable physicochemical properties, showing no incompatibility with the drug; good biocompatibility; and be non-toxic and non-irritating. The encapsulation material should also have good film-forming properties to ensure appropriate drug loading and release performance. The properties of the polymeric encapsulation material itself are a key factor in selecting encapsulation materials, such as permeability, stability, solubility, polymerizability, viscosity, electrical properties, hygroscopicity, and film-forming properties. Commonly used encapsulation materials can be categorized by origin into natural polymers, semi-synthetic polymers, and synthetic polymers, and by biodegradability into biodegradable and non-biodegradable materials. Natural polymers exhibit good biocompatibility and biodegradability in vivo; commonly used materials include gelatin, gum arabic, and albumin. Semi-synthetic polymers include cellulose acetate, ethyl cellulose, hydroxypropyl methylcellulose terephthalate, etc. Among synthetic polymers, aliphatic polyesters are the most widely used biodegradable materials, including polylactic acid, lactic acid-glycolic acid copolymer, polycaprolactone, etc., as well as polyorthoesters, polycyanoacrylates, etc. Synthetic non-biodegradable materials use polyamides, polyacrylic acid resins, etc. Microcapsule preparation methods can be divided into three categories: physicochemical method, chemical method, and physicomechanical method. The method can be selected according to the properties of the core material, the capsule material, and the required microcapsule particle size and drug release requirements. The core material of microcapsules is usually solid or liquid. In addition to active drugs, it may also include other additives, such as stabilizers, diluents, release rate inhibitors and promoters, plasticizers that improve the plasticity of the capsule shell, etc. The antibacterial layer 8 can be a polypeptide copolymer or other antibacterial coatings used in the field of hernia repair patches. It has good antibacterial properties and can reduce the chance of infection for patients.

[0017] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A non-carcinogenic, anti-infective composite hernia repair patch, comprising a mesh polypropylene fiber sheet (1), characterized in that: The mesh polypropylene fiber sheet (1) has mesh polyglycolic acid fiber sheets (2) on both its upper and lower surfaces. The mesh polyglycolic acid fiber sheets (2) are connected to the mesh polypropylene fiber sheet (1) by adhesive (3). The mesh polypropylene fiber sheet (1) is woven from a monofilament structure (4). The monofilament structure (4) includes polypropylene fiber filaments (5), grooves (6), sustained-release capsules (7), and an antibacterial layer (8). The outer side of the polypropylene fiber filaments (5) has multiple grooves (6). The inside of the grooves (6) has a sustained-release capsule (7). The outer side of both the sustained-release capsules (7) and the polypropylene fiber filaments (5) has an antibacterial layer (8).

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