Simple experimental pig bronchoalveolar lavage device
By designing a simple experimental porcine bronchoalveolar lavage device, the problem of damage to the bronchial wall caused by bronchoalveolar lavage devices was solved, achieving the effects of simplified operation, improved efficiency and reduced infection risk.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV (GUANGZHOU RESPIRATORY CENT)
- Filing Date
- 2025-04-10
- Publication Date
- 2026-06-23
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Figure CN224387588U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of animal experimental technology, specifically a simple experimental porcine bronchoalveolar lavage device. Background Technology
[0002] Acute lung injury (ALI) is a hypoxic respiratory failure caused by multiple factors, often progressing to acute respiratory distress syndrome (ARDS). This disease has a high morbidity and mortality rate, making its pathogenesis a subject of great interest. Many researchers have explored its pathophysiological processes by constructing animal models. In experimental research, bronchoalveolar lavage is a widely used technique, particularly important in inducing acute lung injury models in experimental pigs.
[0003] However, existing bronchoalveolar lavage has shortcomings in practical use. In particular, it requires the use of a bronchoscope during lavage, which is an invasive procedure. The bronchoscope is prone to shaking when inserted into the trachea, which can damage the bronchial wall. In addition, it does not have a suction function, so other suction equipment needs to be found, which limits its applicability.
[0004] Therefore, it is particularly important to design a simple experimental porcine bronchoalveolar lavage device for inducing an acute lung injury model after lavage. This device should be easy to operate, minimize damage to the bronchial wall, and have aspiration function to improve the efficiency and accuracy of the experiment. By introducing modern manufacturing equipment, the complexity of the experimental operation can be significantly reduced, time can be saved, and efficiency can be improved. The design and implementation of such a device will provide strong support for the construction of an acute lung injury model. Utility Model Content
[0005] To address the problems mentioned in the background art, the purpose of this utility model is to provide a simple experimental porcine bronchoalveolar lavage device, which has the advantage of reducing damage to the bronchial wall and solves the problem that the inlet tube is prone to shaking and causing damage to the bronchial wall.
[0006] To achieve the above objectives, this utility model provides the following technical solution: a simple experimental porcine bronchoalveolar lavage device, comprising a flexible tube;
[0007] An extension tube is connected to the outside of the tubing, and a three-way tube is connected to the other end of the extension tube. The first outlet of the three-way tube is connected to an air intubation tube, and the second outlet of the three-way tube is connected to a negative pressure suction device. The other end of the tubing is connected to a drip chamber. A flow rate controller A is fitted onto the surface of the tubing. The other end of the drip chamber is connected to a puncture head assembly A and a puncture head assembly B via an adapter. A flow rate controller B is installed inside the puncture head assembly A and the puncture head assembly B and outside the drip chamber. A flow rate controller C is installed on the top of the negative pressure suction device and is fitted onto the surface of the second outlet of the three-way tube.
[0008] As a preferred embodiment of this invention, a sealing ring is fitted onto the surface of the second outlet of the three-way pipe, and the bottom of the sealing ring is fixedly connected to the top of the negative pressure suction device.
[0009] As a preferred embodiment of the present invention, the surface of the drip pot is provided with a scale assembly, which is used in conjunction with the drip pot.
[0010] As a preferred embodiment of this utility model, a small slide rail is fixedly connected to the back of the scale assembly, a slide rod assembly is slidably connected to the inner cavity of the small slide rail, and a positioning plate is fixedly connected to the front of the slide rod assembly.
[0011] As a preferred embodiment of this invention, an auxiliary pull rod is fixedly connected to the top of the positioning plate, and the auxiliary pull rod is used in conjunction with the positioning plate.
[0012] As a preferred embodiment of this invention, both sides of the endotracheal tube are movably connected with antibacterial caps, which are used in conjunction with the endotracheal tube.
[0013] Compared with the prior art, the beneficial effects of this utility model are as follows:
[0014] 1. By introducing modern manufacturing equipment, this utility model can significantly reduce the complexity of experimental operations, save time, and improve efficiency. The design and implementation of this device will provide strong support for the construction of acute lung injury models.
[0015] 2. This utility model, through the setting of the sealing ring, can seal the negative pressure suction device, ensuring that the connection between it and the three-way pipe is sufficiently sealed, and preventing liquid from overflowing during transmission.
[0016] 3. This utility model, through the setting of the scale component, can play an auxiliary role in the dripper, ensuring that the user can more intuitively observe the liquid transfer, thus providing convenience for the user.
[0017] 4. This utility model, through the setting of small slide rails, slide rod assemblies and positioning plates, can provide assistance to users. Users can position and remind the liquid inside the dripper according to their own needs, which further provides users with observation convenience.
[0018] 5. This utility model, through the setting of the auxiliary pull rod, can assist the positioning plate, making it easier for users to move the positioning plate more quickly, thus providing convenience for users.
[0019] 6. This utility model, through the design of the antibacterial cap, can protect the endotracheal tube, preventing the endotracheal tube from being exposed to air and harboring bacteria, thus avoiding the risk of infection when inserted into a living organism. Attached Figure Description
[0020] Figure 1 This is a schematic diagram of the structure of this utility model;
[0021] Figure 2 This is a structural diagram of the drip pot of this utility model;
[0022] Figure 3 This is a structural diagram of the negative pressure suction device of this utility model;
[0023] Figure 4 This is a partial structural diagram of the present invention;
[0024] Figure 5 This is a structural diagram of the three-way pipe of this utility model.
[0025] In the diagram: 1. Tube; 2. Extension tube; 3. T-joint; 4. Air inlet tube; 5. Negative pressure suction device; 6. Drip pot; 7. Flow controller A; 8. Puncture head assembly A; 9. Puncture head assembly B; 10. Flow controller B; 11. Flow controller C; 12. Sealing ring; 13. Scale assembly; 14. Small slide rail; 15. Slide rod assembly; 16. Positioning plate; 17. Auxiliary pull rod; 18. Antibacterial cap. Detailed Implementation
[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0027] like Figures 1 to 5 As shown, the present invention provides a simple experimental porcine bronchoalveolar lavage device, which includes a flexible tube 1.
[0028] The outer side of the flexible tube 1 is connected to the extension tube 2, and the other end of the extension tube 2 is connected to the three-way tube 3. The first outlet of the three-way tube 3 is connected to the air inlet tube 4, and the second outlet of the three-way tube 3 is connected to the negative pressure suction device 5. The other end of the flexible tube 1 is connected to the drip pot 6. The surface of the flexible tube 1 is fitted with a flow rate controller A7. The other end of the drip pot 6 is connected to the puncture head assembly A8 and the puncture head assembly B9 respectively through an adapter. The inner side of the puncture head assembly A8 and the puncture head assembly B9 and the outer side of the drip pot 6 are provided with a flow rate controller B10. The top of the negative pressure suction device 5 is provided with a flow rate controller C11, and the flow rate controller C11 is fitted onto the surface of the second outlet of the three-way tube 3.
[0029] refer to Figure 3A sealing ring 12 is fitted onto the surface of the second outlet of the three-way pipe 3, and the bottom of the sealing ring 12 is fixedly connected to the top of the negative pressure suction device 5.
[0030] As a technical optimization of this utility model, the sealing ring 12 can seal the negative pressure suction device 5, ensuring that the connection between it and the three-way pipe 3 is sufficiently sealed, and preventing liquid from overflowing during transmission.
[0031] refer to Figure 2 The surface of the dripper 6 is provided with a scale assembly 13, which is used in conjunction with the dripper 6.
[0032] As a technical optimization of this utility model, the scale component 13 can play an auxiliary role in the dripper 6, ensuring that the user can more intuitively observe the liquid transfer, thus providing convenience for the user.
[0033] refer to Figure 2 A small slide rail 14 is fixedly connected to the back of the scale assembly 13, and a slide rod assembly 15 is slidably connected to the inner cavity of the small slide rail 14. A positioning plate 16 is fixedly connected to the front of the slide rod assembly 15.
[0034] As a technical optimization of this utility model, the small slide rail 14, slide rod assembly 15 and positioning plate 16 can provide assistance to the user. The user can position and remind the user of the liquid inside the dripper 6 according to their own needs, which further provides the user with observation convenience.
[0035] refer to Figure 2 An auxiliary pull rod 17 is fixedly connected to the top of the positioning plate 16, and the auxiliary pull rod 17 is used in conjunction with the positioning plate 16.
[0036] As a technical optimization of this utility model, the auxiliary pull rod 17 can assist the positioning plate 16, making it easier for users to move the positioning plate 16 more quickly and providing convenience for users.
[0037] refer to Figure 4 Both sides of the endotracheal tube 4 are movably connected with antibacterial caps 18, which are used in conjunction with the endotracheal tube 4.
[0038] As a technical optimization of this utility model, the antibacterial cap 18 can protect the endotracheal tube 4, preventing the endotracheal tube 4 from being exposed to air and having bacteria attached, thus avoiding the risk of infection when inserted into a living organism.
[0039] The working principle and usage process of this utility model are as follows: First, the user only needs to connect the puncture head assembly A8 and puncture head assembly B9 to the saline bag, then close the flow rate controller C11 to allow the saline to pass through the puncture head assembly A8, puncture head assembly B9, drip chamber 6, tubing 1, extension tube 2, three-way tube 3, and finally through the tracheal intubation tube 4 to fill the saline into the pig's lungs. Then, close the flow rate controller A7, open the flow rate controller C11, start the negative pressure suction device 5, and aspirate the saline that has been filled into the experimental pig's lungs.
[0040] In conclusion, this simplified experimental porcine bronchoalveolar lavage device, by incorporating modern manufacturing equipment, can significantly reduce the complexity of experimental operations, save time, and improve efficiency. The design and implementation of this device will provide strong support for the construction of acute lung injury models.
[0041] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.
[0042] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A simple experimental porcine bronchoalveolar lavage device, comprising a flexible tube (1); characterized in that: The outer side of the flexible tube (1) is connected to an extension tube (2), the other end of the extension tube (2) is connected to a three-way tube (3), the first outlet of the three-way tube (3) is connected to an air inlet tube (4), the second outlet of the three-way tube (3) is connected to a negative pressure suction device (5), the other end of the flexible tube (1) is connected to a drip pot (6), a flow rate controller A (7) is fitted onto the surface of the flexible tube (1), the other end of the drip pot (6) is connected to a puncture head assembly A (8) and a puncture head assembly B (9) respectively via an adapter, a flow rate controller B (10) is provided on the inner side of the puncture head assembly A (8) and the puncture head assembly B (9) and located on the outer side of the drip pot (6), a flow rate controller C (11) is provided on the top of the negative pressure suction device (5), and the flow rate controller C (11) is fitted onto the surface of the second outlet of the three-way tube (3).
2. The simplified experimental porcine bronchoalveolar lavage device according to claim 1, characterized in that: A sealing ring (12) is fitted onto the surface of the second outlet of the three-way pipe (3), and the bottom of the sealing ring (12) is fixedly connected to the top of the negative pressure suction device (5).
3. The simplified experimental porcine bronchoalveolar lavage device according to claim 1, characterized in that: The surface of the dripper (6) is provided with a scale assembly (13), which is used in conjunction with the dripper (6).
4. A simplified experimental porcine bronchoalveolar lavage device according to claim 3, characterized in that: The back of the scale assembly (13) is fixedly connected to a small slide rail (14), the inner cavity of the small slide rail (14) is slidably connected to a slide rod assembly (15), and the front of the slide rod assembly (15) is fixedly connected to a positioning plate (16).
5. A simplified experimental porcine bronchoalveolar lavage device according to claim 4, characterized in that: An auxiliary pull rod (17) is fixedly connected to the top of the positioning plate (16), and the auxiliary pull rod (17) is used in conjunction with the positioning plate (16).
6. A simplified experimental porcine bronchoalveolar lavage device according to claim 1, characterized in that: Both sides of the endotracheal tube (4) are movably connected with antibacterial caps (18), which are used in conjunction with the endotracheal tube (4).