A tissue section hyaluronic acid staining kit

Abstract

The utility model relates to kit technical field, and disclose a kind of tissue section hyaluronic acid staining kit, including kit, the top of the kit is provided with box cover, the inside of the kit is provided with sponge pad, the inner wall of the kit is provided with fixing device;The fixing device includes hydraulic cylinder, the bottom of the hydraulic cylinder is fixedly connected in the inside of sponge pad, the inside of one end of the hydraulic cylinder is slidably connected with force bar by piston, the inside of the other end of the hydraulic cylinder is slidably connected with hydraulic ram by another piston.The utility model through fixing device, so that rubber bar will be because the extrusion compression spring of reagent bottle moves to through slot when rubber bar contacts reagent bottle, and then one end of rubber bar can be fixed to reagent bottle when it is against through slot, different number of reagent bottles can be fixed by telescopic rod, to prevent from shaking when carrying and make reagent bottle collide, cause breakage.

Description

Technical Field

[0001] This utility model relates to the field of reagent kit technology, specifically a hyaluronic acid staining kit for tissue sections. Background Technology

[0002] Hyaluronic acid is a non-sulfated glycosaminoglycan widely distributed in the extracellular matrix, especially in connective tissue, skin, synovial fluid, eyes, and umbilical cord. Hyaluronic acid plays a crucial role in physiological processes such as tissue repair, cell migration, proliferation, differentiation, and immune responses. Studies have found that variations in the molecular weight, concentration, and distribution pattern of hyaluronic acid have significant impacts on a variety of diseases.

[0003] Existing technology, such as the patent with publication number CN212149732U, discloses a reagent kit for detecting the degree of liver fibrosis. The kit includes a kit body, reagent tubes, and a holder, with the kit body and reagent tubes respectively fixed to the holder; a storage box with a lid at the top, a slotted partition in the middle cavity, and a water reservoir at the bottom; the reagent kit is placed at one end of the slotted partition, and a storage compartment is located at the other end; the top of the water reservoir is sealed with a waterproof rubber strip, and a dry ice chamber is located above the water reservoir; a temperature sensing component is also provided on one side wall of the storage box. This utility model's reagent kit for detecting the degree of liver fibrosis can be conveniently and quickly used for quantitative detection of the levels of hyaluronic acid, laminin, type III procollagen N-terminal peptide, and type IV collagen in the serum of patients with hepatitis B, hepatitis C, or other chronic liver diseases, and can provide a relatively accurate diagnosis of different stages of liver fibrosis.

[0004] While the aforementioned existing technologies have significant beneficial effects, they still have shortcomings:

[0005] The existing technology described above makes it difficult to fix the reagents and contents of the kit when carrying them, which can cause damage to the reagents due to shaking during movement. Therefore, a tissue section hyaluronic acid staining kit is proposed. Utility Model Content

[0006] To address the shortcomings of existing technologies, this invention provides a hyaluronic acid staining kit for tissue sections. The moving fixing block moves a rubber rod to secure the reagent bottle. When the rubber rod contacts the reagent bottle, it compresses the elastic spring due to the pressure of the bottle and moves into the groove. When one end of the rubber rod abuts against the groove, the reagent bottle is secured. The telescopic rod allows for the securing of different numbers of reagent bottles, preventing shaking and collisions that could lead to breakage during transport.

[0007] To achieve the above objectives, this utility model provides the following technical solution: a tissue section hyaluronic acid staining kit, comprising a kit, a lid on the top of the kit, a sponge pad inside the kit, and a fixing device on the inner wall of the kit; the fixing device includes a hydraulic cylinder, the bottom of which is fixedly connected to the inside of the sponge pad, a force-bearing rod slidably connected to one end of the hydraulic cylinder via a piston, and a hydraulic rod slidably connected to the other end of the hydraulic cylinder via another piston, the hydraulic rod slidingly penetrating the inside of the sponge pad, a connecting plate fixedly connected to the side of the hydraulic rod, a telescopic rod fixedly connected to the side of the connecting plate, and a fixing block fixedly connected to the side of the telescopic rod.

[0008] Preferably, the fixing block has a through groove inside, a rubber rod slides through the side of the fixing block, and a spring is fixedly connected to the side of the rubber rod. The end of the spring away from the rubber rod is fixedly connected to the inside of the through groove. The rubber rod is used to fix the reagent bottle stored in the reagent kit, and the function of the spring is to drive the rubber rod to reset.

[0009] Preferably, a return spring is fixedly connected to the circumferential surface of the force-bearing rod, and the end of the return spring away from the force-bearing rod is fixedly connected to the top of the hydraulic cylinder. The function of the return spring is to allow the force-bearing rod to return to its original position when the lid does not press against it.

[0010] Preferably, the number of telescopic rods is set to two, and they are symmetrical to each other along the vertical central axis of the connecting plate. The number of fixing devices is set to two, and they are symmetrical to each other along the vertical central axis of the reagent kit. The top of the force-bearing rod is located on the displacement trajectory of the lid. The purpose of setting two fixing devices is to better fix the reagent bottle.

[0011] Preferably, the front side of the reagent kit is provided with a locking device, the locking device including a retaining ring, the side of the retaining ring being fixedly connected to the side of the lid, the front side of the reagent kit being fixedly connected to a locking frame, the inner wall of the locking frame being slidably connected to a push block, the back side of the push block being fixedly connected to a connecting ring, and the inner wall of the connecting ring being fixedly connected to a locking block. The function of the locking block is to cooperate with the retaining ring to lock the lid and the reagent kit together.

[0012] Preferably, a flexible spring is fixedly connected to the inner wall of the locking frame, and the end of the flexible spring away from the locking frame is fixedly connected to the back side of the push block. The function of the flexible spring is to allow the block to be reset by the push block using the flexible spring when the retaining ring no longer presses against the block.

[0013] Preferably, the top of the locking block is located on the displacement trajectory of the locking ring, the shape of the locking block is set to rectangle, and the side cross-section of the locking block is set to be inclined. The purpose of the top of the locking block being located on the displacement trajectory of the locking ring is to push the locking block when the locking ring moves, and the purpose of setting the side cross-section of the locking block to be inclined is to allow the locking ring to push the locking block better.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] This invention uses a fixing device that allows the moving fixing block to move a rubber rod to fix the reagent bottle. When the rubber rod contacts the reagent bottle, it will move into the through groove due to the compression of the elastic spring by the reagent bottle. When one end of the rubber rod abuts against the through groove, the reagent bottle can be fixed. The telescopic rod can fix different numbers of reagent bottles, thereby preventing shaking during carrying and causing the reagent bottles to collide and break.

[0016] This invention uses a locking device so that when the retaining ring contacts the retaining block, the retaining ring will use the inclined surface of the retaining block to squeeze the retaining block to move. Then, when the bottom end of the retaining ring passes the retaining block, the retaining block will be no longer squeezed by the retaining ring and will be reset by the push block using a flexible spring to drive the connecting ring. The reset retaining block will then enter the retaining ring, thereby completing the locking of the box cover.

[0017] Other features and advantages of this invention will be set forth in the description which follows, and will be apparent in part from the description, or may be learned by practicing the invention. The objects and other advantages of this invention can be realized and obtained by means of the structures pointed out in the description, claims, and drawings. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the main structure of the present utility model;

[0019] Figure 2 This is a schematic diagram of the structure of the fixed cutting device of this utility model;

[0020] Figure 3 This is a schematic diagram of the locking device structure of this utility model;

[0021] Figure 4 This utility model Figure 2 A three-dimensional magnified structural diagram at point A in the middle;

[0022] Figure 5 This utility model Figure 3 A three-dimensional magnified structural diagram at point B.

[0023] In the diagram: 1. Reagent kit; 2. Box lid; 3. Sponge pad; 4. Fixing device; 41. Hydraulic cylinder; 42. Force rod; 43. Hydraulic rod; 44. Connecting plate; 45. Telescopic rod; 46. Fixing block; 47. Through groove; 48. Rubber rod; 49. Elastic spring; 410. Return spring; 5. Locking device; 51. Snap ring; 52. Locking frame; 53. Push block; 54. Connecting ring; 55. Clamping block; 56. Flexible spring. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0025] Please see Figure 1 - Figure 5 This embodiment of a tissue section hyaluronic acid staining kit includes a kit 1, a lid 2 on the top of the kit 1, a sponge pad 3 inside the kit 1, and a fixing device 4 on the inner wall of the kit 1. The fixing device 4 includes a hydraulic cylinder 41, the bottom of which is fixedly connected to the inside of the sponge pad 3. One end of the hydraulic cylinder 41 is slidably connected to a force rod 42 via a piston, and the other end of the hydraulic cylinder 41 is slidably connected to a hydraulic rod 43 via another piston. The hydraulic rod 43 slides through the inside of the sponge pad 3. A connecting plate 44 is fixedly connected to the side of the hydraulic rod 43, a telescopic rod 45 is fixedly connected to the side of the connecting plate 44, and a fixing block 46 is fixedly connected to the side of the telescopic rod 45. A through groove 47 is opened inside the fixing block 46, and a rubber rod 48 slides through the side of the fixing block 46. A spring 4 is fixedly connected to the side of the rubber rod 48. 9. The end of the elastic spring 49 away from the rubber rod 48 is fixedly connected to the inside of the through groove 47. The rubber rod 48 is used to fix the reagent bottle stored in the reagent kit 1. The function of the elastic spring 49 is to drive the rubber rod 48 to reset. A reset spring 410 is fixedly connected to the circumferential surface of the force rod 42. The end of the reset spring 410 away from the force rod 42 is fixedly connected to the top of the hydraulic cylinder 41. The function of the reset spring 410 is to allow the force rod 42 to reset when the lid 2 does not press against it. There are two telescopic rods 45, which are symmetrical about each other along the vertical central axis of the connecting plate 44. There are two fixing devices 4, which are symmetrical about each other along the vertical central axis of the reagent kit 1. The top of the force rod 42 is located on the displacement trajectory of the lid 2. The purpose of setting two fixing devices 4 is to better fix the reagent bottle.

[0026] like Figure 1 - Figure 2 , Figure 4 As shown, the reagent kit in this invention is similar to existing reagent kits, such as the reagent kit for detecting the degree of liver fibrosis with publication number CN212149732U. The main improvement of this invention is that the movement trajectory of the lid 2 can drive the fixing device 4 to fix the reagent bottle placed in the sponge pad 3. When the lid 2 rotates downward and closes, it pushes the force rod 42. When the force rod 42 is pushed by the lid 2, it moves into the hydraulic cylinder 41. When the force rod 42 moves into the hydraulic cylinder 41, the hydraulic rod 43 moves outward due to the squeezing force of the moving force rod 42. When rod 43 moves, it can drive telescopic rod 45 to move via connecting plate 44. In turn, the telescopic rod 45 can drive fixed block 46 to move, which in turn can drive rubber rod 48 to move and fix the reagent bottle. When rubber rod 48 contacts the reagent bottle, it will compress spring spring 49 due to the pressure of the reagent bottle and move into through groove 47. When one end of rubber rod 48 abuts against through groove 47, the reagent bottle can be fixed. The telescopic rod 45 can fix different numbers of reagent bottles, thereby preventing shaking during carrying and causing the reagent bottles to collide and break.

[0027] like Figure 3 , Figure 5 As shown, a locking device 5 is provided on the front side of the reagent kit 1. The locking device 5 includes a retaining ring 51, the side of which is fixedly connected to the side of the lid 2. A locking frame 52 is fixedly connected to the front side of the reagent kit 1. A push block 53 is slidably connected to the inner wall of the locking frame 52. A connecting ring 54 is fixedly connected to the back side of the push block 53. A locking block 55 is fixedly connected to the inner wall of the connecting ring 54. The function of the locking block 55 is to cooperate with the retaining ring 51 to lock the lid 2 and the reagent kit 1. A flexible spring 56 is fixedly connected to the inner wall of the locking frame 52. The flexible spring 56 is located away from the locking frame 52. The end is fixedly connected to the back side of the push block 53. The function of the flexible spring 56 is to allow the block 55 to be reset by the push block 53 when the retaining ring 51 no longer presses the block 55. The top of the block 55 is located on the displacement trajectory of the retaining ring 51. The shape of the block 55 is set as rectangular, and the side section of the block 55 is set as an inclined surface. The purpose of the top of the block 55 being located on the displacement trajectory of the retaining ring 51 is to push the block 55 when the retaining ring 51 moves. The purpose of setting the side section of the block 55 as an inclined surface is to allow the retaining ring 51 to push the block 55 better.

[0028] like Figure 3 , Figure 5As shown, the movement of the lid 2 can drive the locking device 5. When the lid 2 rotates downward, it can drive the retaining ring 51 to move. When the retaining ring 51 moves to the appropriate position, it will contact the retaining block 55. When the retaining ring 51 contacts the retaining block 55, the retaining ring 51 will use the inclined surface of the retaining block 55 to squeeze the retaining block 55 to move. Then, when the bottom end of the retaining ring 51 passes the retaining block 55, the retaining block 55 will be unable to be squeezed by the retaining ring 51 and will be pushed by the push block 53 and the flexible spring 56 to drive the connecting ring 54 to reset. The reset retaining block 55 will enter the retaining ring 51, thereby completing the locking of the lid 2. When it is necessary to open the lid 2, the push block 53 is pressed into the locking frame 52. When the push block 53 moves, it will drive the connecting ring 54 to move. When the connecting ring 54 moves, it will drive the retaining block 55 to move. When the retaining block 55 moves, it can push the retaining ring 51. When the retaining ring 51 is no longer blocked, the lid 2 can be opened.

[0029] Obviously, the above embodiments of this utility model are merely examples for clearly illustrating the present utility model, and are not intended to limit the implementation of the present utility model. Those skilled in the art can make other variations or modifications based on the above description. It is neither necessary nor possible to exhaustively describe all embodiments here. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this utility model should be included within the protection scope of the claims of this utility model.

Claims

1. A tissue section hyaluronic acid staining kit, comprising kit (1), characterized in that, The reagent kit (1) is provided with a lid (2) on the top, a sponge pad (3) is provided inside the reagent kit (1), and a fixing device (4) is provided on the inner wall of the reagent kit (1). The fixing device (4) includes a hydraulic cylinder (41), the bottom of which is fixedly connected to the inside of the sponge pad (3). One end of the hydraulic cylinder (41) is slidably connected to a force rod (42) via a piston. The other end of the hydraulic cylinder (41) is slidably connected to a hydraulic rod (43) via another piston. The hydraulic rod (43) slides through the inside of the sponge pad (3). A connecting plate (44) is fixedly connected to the side of the hydraulic rod (43). A telescopic rod (45) is fixedly connected to the side of the connecting plate (44). A fixing block (46) is fixedly connected to the side of the telescopic rod (45).

2. The hyaluronic acid staining kit for tissue sections according to claim 1, characterized in that, The fixed block (46) has a through groove (47) inside. A rubber rod (48) slides through the side of the fixed block (46). A spring (49) is fixedly connected to the side of the rubber rod (48). The end of the spring (49) away from the rubber rod (48) is fixedly connected to the inside of the through groove (47).

3. The hyaluronic acid staining kit for tissue sections according to claim 1, characterized in that, A return spring (410) is fixedly connected to the circumferential surface of the force-bearing rod (42), and the end of the return spring (410) away from the force-bearing rod (42) is fixedly connected to the top of the hydraulic cylinder (41).

4. The hyaluronic acid staining kit for tissue sections according to claim 1, characterized in that, The number of telescopic rods (45) is set to two, and they are symmetrical to each other along the vertical central axis of the connecting plate (44). The number of fixing devices (4) is set to two, and they are symmetrical to each other along the vertical central axis of the kit (1). The top of the force rod (42) is located on the displacement trajectory of the box cover (2).

5. The hyaluronic acid staining kit for tissue sections according to claim 1, characterized in that, The reagent kit (1) is provided with a locking device (5) on its front side. The locking device (5) includes a retaining ring (51). The side of the retaining ring (51) is fixedly connected to the side of the lid (2). The front side of the reagent kit (1) is fixedly connected to a locking frame (52). The inner wall of the locking frame (52) is slidably connected to a push block (53). The back side of the push block (53) is fixedly connected to a connecting ring (54). The inner wall of the connecting ring (54) is fixedly connected to a locking block (55).

6. The hyaluronic acid staining kit for tissue sections according to claim 5, characterized in that, A flexible spring (56) is fixedly connected to the inner wall of the locking frame (52), and one end of the flexible spring (56) away from the locking frame (52) is fixedly connected to the back side of the push block (53).

7. A tissue section hyaluronic acid staining kit according to claim 5, characterized in that, The top of the card block (55) is located on the displacement trajectory of the retaining ring (51). The shape of the card block (55) is set as a rectangle, and the side section of the card block (55) is set as an inclined surface.

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