A cell culture centrifuge tube

By introducing a linkage design of baffles, side plates, guide rods, and reset springs into the cell culture centrifuge tubes and a multi-seal structure, the problems of convenient feeding and insufficient sealing in the existing technology are solved, and efficient and safe cell culture operation is achieved.

CN224411756UActive Publication Date: 2026-06-26JIANGSU COLLEGE OF NURSING

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
JIANGSU COLLEGE OF NURSING
Filing Date
2025-07-01
Publication Date
2026-06-26

AI Technical Summary

Technical Problem

Existing cell culture centrifuge tubes lack convenient feeding designs during operation, relying on needle plugging for inoculation, resulting in low experimental efficiency, time and labor consumption, and easy impact on sealing.

Method used

The design incorporates a combination of a stop block, side plate, guide rod, and return spring, along with a multi-seal structure consisting of threaded connection, rubber gasket sealing, and embedded sealing ring, enabling convenient opening and closing of the feed inlet and multiple seals to reduce the chance of contamination.

Benefits of technology

It improves the ease of operation and safety of experiments, reduces time and effort costs, ensures the accuracy and reliability of experimental results, and enhances the stability and service life of centrifuge tubes.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a kind of cell culture centrifugal tube, it is related to cell culture experimental equipment technical field, specifically including cell culture centrifugal tube outer tube, the top of cell culture centrifugal tube outer tube is provided with tube cover, cell culture centrifugal tube outer tube is connected with the thread of tube cover, the top of tube cover is provided with protection plate, the top of tube cover is slidably connected with stop block, the bottom of stop block is embedded with rubber pad, corresponding two sides of stop block are fixedly installed with side plate, two side plates are inserted into the inside of tube cover and slidably connected with it, the inside of two side plates is provided with guide rod. The cell culture centrifugal tube of the application adopts multiple sealing structure of thread connection, rubber pad sealing, sealing ring embedding, effectively isolates outside air and impurity, avoids sample pollution, guarantees that experimental result is accurate and reliable, reduces the risk of experiment failure;Meanwhile, stop block is cooperatively designed by side plate, guide rod and return spring, realizes simple operation of feeding port, reduces experimental time and energy cost.
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Description

Technical Field

[0001] This utility model relates to the field of cell culture experimental equipment technology, specifically a cell culture centrifuge tube. Background Technology

[0002] In life science research, biopharmaceuticals, and other fields, cell culture is a fundamental and crucial experimental procedure, and cell culture centrifuge tubes, as commonly used experimental equipment, have a significant impact on experimental results. Currently, commercially available cell culture centrifuge tubes are generally made of polymer materials such as polypropylene (PP). These materials have good chemical stability and corrosion resistance, and can meet the chemical compatibility requirements of general cell culture processes.

[0003] Chinese Patent Announcement No. CN 208857309 U provides a cell culture centrifuge tube, including a tube body and a sealing cap connected to the tube body. The sealing cap has an opening on its top wall, and a soft plug is embedded in the opening. The soft plug includes a lower circular pad extending to the lower surface of the top wall. The lower circular pad is pressed against the open end face of the tube body when the sealing cap is closed. By adopting a soft plug structure that can abut against the opening of the tube body, the sealing performance is further improved compared with the prior art.

[0004] In existing technologies, cell culture centrifuge tubes rely solely on needles to pierce soft stoppers during cell inoculation and other operations. Frequent needle piercing of the soft stopper demands a high level of skill and expertise from the operator. Novice operators are prone to errors such as incorrect piercing angles and improper force control, and repeated piercing can also cause wear on the soft stopper, affecting its sealing performance. From an operational efficiency perspective, each inoculation requires a separate needle, making batch and rapid operations impossible. Compared to centrifuge tubes with convenient feeding mechanisms, the operation time increases exponentially when processing large numbers of cell samples. Therefore, we propose an improvement to this technology: a cell culture centrifuge tube. Utility Model Content

[0005] The purpose of this invention is to address the limitations of current cell culture centrifuge tube operation methods, such as the lack of convenient feeding design, reliance on needle plugging for inoculation, and the failure to optimize the experimental process, resulting in low experimental efficiency and high time and labor costs.

[0006] To achieve the above-mentioned objectives, this utility model provides the following technical solution:

[0007] A cell culture centrifuge tube, through the linkage design of a baffle, side plate, guide rod and reset spring, realizes convenient opening and closing of the feed inlet, and the operation is simple and smooth. It can effectively reduce the chance of contamination and reduce time and effort costs, thereby improving the above-mentioned problems.

[0008] The application is as follows:

[0009] A cell culture centrifuge tube includes an outer tube, a cap at the top of the outer tube, the outer tube being threadedly connected to the cap, a protective plate at the top of the cap, a stop block slidably connected to the top of the cap, a rubber pad embedded at the bottom of the stop block, side plates fixedly installed on opposite sides of the stop block, both side plates being inserted into and slidably connected to the cap, guide rods being installed inside both side plates, each guide rod penetrating through and slidably connected to the side plates, and multiple return springs fixedly installed on one side of the stop block, the ends of the multiple return springs away from the cap being fixedly connected to the cap.

[0010] As a preferred technical solution of this application, a conical block is fixedly installed at the bottom of the pipe cover, and both the pipe cover and the conical block are provided with a communicating feed inlet, and the stop block is slidably connected to the feed inlet;

[0011] As a preferred technical solution of this application, an intermediate reinforcing layer tube is fixedly installed inside the outer tube of the cell culture centrifuge tube, an inner protective layer tube is fixedly installed inside the tube cap, and the conical block is slidably connected to the inner protective layer tube.

[0012] As a preferred technical solution of this application, a U-shaped insert plate is fixedly installed at the bottom of the protective plate, a groove that mates with the U-shaped insert plate is opened at the top of the protective plate, a rubber pad is fixedly installed at the top of the protective plate and inside the groove, a card slot is opened on the protective plate, and the protective plate is made of transparent plastic material.

[0013] As a preferred technical solution of this application, a push plate is slidably connected to the top of the tube cover. A connecting rod is fixedly installed on the side of the push plate near the stop and on the corresponding sides of the feed inlet. The two ends of the two connecting rods are respectively fixedly connected to the stop and the push plate.

[0014] As a preferred technical solution of this application, the outer side of the cell culture centrifuge tube is printed with scale lines, and a sealing ring is embedded at the junction of the tube cap, the outer tube of the cell culture centrifuge tube, the inner tube of the protective layer, and the baffle.

[0015] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0016] In the scheme of this application:

[0017] The cell culture centrifuge tube adopts a multi-seal structure with threaded connection, rubber gasket sealing, and sealing ring inlay, which effectively isolates external air and impurities, avoids sample contamination, ensures accurate and reliable experimental results, and reduces the risk of experimental failure. At the same time, the baffle, through the coordinated design of side plate, guide rod and reset spring, realizes simple operation of the feed port and reduces experimental time and effort costs.

[0018] The centrifuge tubes for cell culture are made of high-strength materials, forming a double-reinforced structure with an inner reinforcing layer inside the outer tube and an inner protective layer inside the cap. At the same time, the conical block is slidably connected to the inner protective layer, which not only ensures smooth feeding but also provides additional support for the internal structure of the cap, further improving the overall stability and reliability of the centrifuge tubes. Attached Figure Description

[0019] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0020] Figure 2 This is a front sectional view of the present invention.

[0021] Figure 3 This is an exploded view of a partial structure of the present invention;

[0022] Figure 4 This is a schematic diagram of the centrifuge tube structure of this utility model.

[0023] Explanation of the markings on the attached diagrams: 1. Outer tube of cell culture centrifuge tube; 2. Tube cap; 3. Protective plate; 4. Middle tube of reinforcing layer; 5. Inner tube of protective layer; 7. Conical block; 8. Feed inlet; 9. Stop block; 10. Side plate; 11. Return spring; 12. Guide rod; 13. Connecting rod; 14. Push plate; 15. U-shaped insert plate; 16. Card slot. Detailed Implementation

[0024] The present invention will be further described in detail below with reference to the accompanying drawings.

[0025] This specific embodiment is merely an explanation of the present utility model and is not intended to limit the present utility model. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but as long as they are within the scope of the claims of the present utility model, they are protected by patent law.

[0026] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0027] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0028] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0029] In this utility model, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0030] Example 1: Please refer to the appendix of the instruction manual. Figure 1-4 A cell culture centrifuge tube includes an outer tube 1, a cap 2 at the top of the outer tube 1, the outer tube 1 and the cap 2 being threadedly connected, a protective plate 3 at the top of the cap 2, a stop 9 slidably connected to the top of the cap 2, a rubber pad embedded at the bottom of the stop 9, side plates 10 fixedly installed on opposite sides of the stop 9, both side plates 10 being inserted into the cap 2 and slidably connected thereto, guide rods 12 being provided inside both side plates 10, the two guide rods 12 passing through the two side plates 10 respectively and slidably connected thereto, and multiple return springs 11 fixedly installed on one side of the stop 9, the ends of the multiple return springs 11 away from the cap 2 being fixedly connected to the cap 2.

[0031] In this embodiment of the utility model, the push plate 14 drives the stop block 9 to slide through the connecting rod 13. When it is necessary to open the feed port 8, the push plate 14 is pushed, the reset spring 11 is compressed, and the stop block 9 leaves the feed port 8. When the push plate 14 is released, the reset spring 11 is reset, and the stop block 9 is driven to close the feed port 8 again.

[0032] In this embodiment of the invention, by adopting a multi-seal design, the cell culture samples are effectively prevented from coming into contact with the external environment during storage, transportation and centrifugation, thus avoiding sample contamination, ensuring the accuracy and reliability of cell culture experiments, and reducing the risk of experimental failure.

[0033] Example 2: Please refer to the appendix of the instruction manual. Figure 1-4 In a preferred embodiment of the present invention, a conical block 7 is fixedly installed at the bottom of the pipe cover 2, and both the pipe cover 2 and the conical block 7 are provided with a connected feed inlet 8. The stop block 9 is slidably connected to the feed inlet 8.

[0034] The inner tube 4 of the cell culture centrifuge tube is fixedly installed inside the outer tube 1, and the inner tube 5 of the protective layer is fixedly installed inside the tube cap 2. The conical block 7 is slidably connected to the inner tube 5 of the protective layer.

[0035] A U-shaped insert plate 15 is fixedly installed at the bottom of the protective plate 3. A groove that mates with the U-shaped insert plate 15 is opened at the top of the protective plate 3. A rubber pad is fixedly installed at the top of the protective plate 3 and inside the groove. A card slot 16 is opened on the protective plate 3. The protective plate 3 is made of transparent plastic material.

[0036] A push plate 14 is slidably connected to the top of the pipe cover 2. A connecting rod 13 is fixedly installed on the side of the push plate 14 near the stop block 9 and on the corresponding sides of the feed inlet 8. Both ends of the two connecting rods 13 are fixedly connected to the stop block 9 and the push plate 14, respectively.

[0037] The outer tube 1 of the cell culture centrifuge tube is printed with graduation lines, and the junction of the tube cap 2 with the outer tube 1 of the cell culture centrifuge tube, the inner tube 5 of the protective layer and the block 9 is inlaid with a sealing ring.

[0038] In this embodiment of the invention, the conical block 7 at the bottom of the tube cap 2 slides in conjunction with the inner tube 5 of the protective layer. During feeding, the sample can smoothly enter the centrifuge tube through the feed inlet 8 and the conical block 7. The conical structure helps to guide the sample flow and reduce sample residue.

[0039] The reinforcing layer middle tube 4 and the protective layer inner tube 5 are made of high-strength materials. During centrifugation, they can withstand the centrifugal force generated by high-speed rotation, share the pressure on the outer tube 1 and the cap 2 of the cell culture centrifuge tube, and prevent the centrifuge tube from breaking due to excessive force. The reinforced structural design improves the overall strength and stability of the centrifuge tube, extends the service life of the centrifuge tube, reduces sample loss and experimental accidents caused by centrifuge tube breakage, ensures the safety of experimental personnel, and also reduces experimental costs.

[0040] The protective plate 3 is made of transparent plastic. The U-shaped insert 15 at the bottom can be inserted into the groove at the top of the tube cap 2 to achieve splicing, further protecting the top of the tube cap 2 from dust. The card slot 16 on the protective plate 3 can be used to insert cards labeled with sample information, such as cell type, culture time, and experiment number. The transparent protective plate 3 can protect the card information from damage and make it convenient for experimental personnel to quickly view the sample information.

[0041] In this embodiment of the utility model, the tube cap 2 is connected to the outer tube 1 of the cell culture centrifuge tube by a thread, and a sealing ring is embedded at the junction of the tube cap 2 with the outer tube 1 of the cell culture centrifuge tube, the inner tube 5 of the protective layer and the block 9.

[0042] When the rotating tube cap 2 is tightened, the threaded structure provides a tightening force, and the sealing ring fills the gap under compression to form a sealed space; the rubber pad embedded at the bottom of the stop block 9 can fit tightly against the surface of the tube cap 2 when it slides to the feed inlet 8, further sealing the feed inlet 8.

[0043] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any way. Any simple modifications, equivalent changes and alterations made to the above embodiments based on the technical essence of the present utility model shall fall within the scope of the technical solution of the present utility model.

Claims

1. A cell culture centrifuge tube, comprising an outer tube (1) for cell culture centrifuge tube, characterized in that, The cell culture centrifuge tube outer tube (1) is provided with a tube cap (2) at the top. The cell culture centrifuge tube outer tube (1) is threadedly connected to the tube cap (2). The tube cap (2) is provided with a protective plate (3) at the top. The tube cap (2) is slidably connected with a stop block (9) at the top. The bottom of the stop block (9) is inlaid with a rubber pad. Side plates (10) are fixedly installed on the corresponding sides of the stop block (9). The two side plates (10) are inserted into the tube cap (2) and slidably connected to it. The two side plates (10) are provided with guide rods (12) inside. The two guide rods (12) pass through the two side plates (10) respectively and slidably connected to them. Multiple return springs (11) are fixedly installed on one side of the stop block (9). The ends of the multiple return springs (11) away from the tube cap (2) are fixedly connected to the tube cap (2).

2. The cell culture centrifuge tube according to claim 1, characterized in that, A conical block (7) is fixedly installed at the bottom of the pipe cover (2). Both the pipe cover (2) and the conical block (7) have a connected feed inlet (8). The stop block (9) is slidably connected to the feed inlet (8).

3. A cell culture centrifuge tube according to claim 2, characterized in that, The inner part of the outer tube (1) of the cell culture centrifuge tube is fixedly installed with an intermediate tube (4) of the reinforcing layer, and the inner part of the tube cap (2) is fixedly installed with an inner tube (5) of the protective layer. The conical block (7) is slidably connected to the inner tube (5) of the protective layer.

4. A cell culture centrifuge tube according to claim 1, characterized in that, The bottom of the protective plate (3) is fixedly installed with a U-shaped insert plate (15), the top of the protective plate (3) is provided with a groove that matches the U-shaped insert plate (15), a rubber pad is fixedly installed on the top of the protective plate (3) and inside the groove, a card slot (16) is provided on the protective plate (3), and the protective plate (3) is made of transparent plastic material.

5. A cell culture centrifuge tube according to claim 2, characterized in that, The top of the tube cover (2) is slidably connected to a push plate (14). The push plate (14) is fixedly installed with connecting rods (13) on the side near the stop block (9) and on the corresponding sides of the feed inlet (8). The two ends of the two connecting rods (13) are fixedly connected to the stop block (9) and the push plate (14) respectively.

6. A cell culture centrifuge tube according to claim 1, characterized in that, The outer tube (1) of the cell culture centrifuge tube is printed with graduation lines, and the junction of the tube cap (2) with the outer tube (1) of the cell culture centrifuge tube, the inner tube (5) of the protective layer and the block (9) is inlaid with a sealing ring.