A graduated and squeezeable container for human papillomavirus (HPV) preservation solution.

Abstract

This invention provides a graduated and squeezeable container for human papillomavirus (HPV) preservation solution, comprising a tube body and a cap at the top of the tube body. The tube body has graduations on its side wall and is a flexible tube made of LDPE. A silicone mold with multiple 0.2mm diameter mesh openings is located at the top inlet of the tube body. The cap is an inverted cone shape and is fastened to the top inlet of the tube body. A 0.2cm diameter sample dispensing port is located at the top of the cap. This container has a simple structure and is easy to operate. Squeezing effectively removes impurities and mucus, extracting effective nucleic acids, effectively avoiding sample contamination, improving work efficiency, avoiding wear and tear on the pipette tip due to re-examination, and reducing consumable costs.

Description

Technical Field

[0001] This utility model belongs to the field of medical testing and inspection technology, specifically relating to a graduated and squeezeable container for human papillomavirus preservation solution. Background Technology

[0002] HPV testing is a commonly used clinical technique for cervical cancer screening. It involves collecting cervical swab cells from the cervix to determine the presence of the HPV virus, a pathogenic factor for cervical cancer. The mucus and blood in the cervical swab sample significantly affect the testing process and results. While a pipette is used for HPV extraction, impurities in the cervical sample can hinder the transfer of preservation solution to nucleic acid lysis buffer. Existing preservation bottles are too rigid to be squeezed, making it impossible to remove impurities and resulting in the inability to extract effective nucleic acids. This repeated aspiration process makes the sample highly susceptible to contamination, increases the workload for the operator, and the need for result retesting means patients cannot receive results promptly. Furthermore, current technology is wasteful of pipette tips, increasing consumable costs. Utility Model Content

[0003] The purpose of this invention is to overcome the problems of existing preservation bottles, such as inconvenience in operation, inability to remove impurities, inability to extract effective nucleic acids, repeated aspiration process that makes the specimens highly susceptible to contamination, and increased workload for operators and increased cost of consumables.

[0004] To achieve the above objectives, this utility model provides a container for a graduated and squeezeable human papillomavirus preservation solution, comprising a tube body and a cap disposed at the top of the tube body, wherein the tube body is provided with graduations on the side wall, and the tube body is a flexible tube made of LDPE.

[0005] A silicone mold is provided at the top inlet of the tube, and the silicone mold has multiple mesh holes with a diameter range of 0.15 to 0.25 mm.

[0006] The cap is an inverted cone shape and is fastened to the top inlet of the tube body;

[0007] The top of the cap has a sample inlet with a diameter of 0.2 cm.

[0008] As a further improvement, the outer wall of the top opening of the tube body is provided with a smooth top section and an external threaded section located below the smooth top section in sequence. The external threaded section is used to thread a protective cover that is fastened to the tube body and the cap.

[0009] As a further improvement, the diameter of the mesh openings on the silicone mold is 0.2 mm.

[0010] The advantages of this utility model are:

[0011] With its simple structure and convenient operation, it can effectively remove impurities and mucus by squeezing, extract effective nucleic acids, effectively avoid sample contamination, improve work efficiency, avoid wear and tear on the sample tip due to re-examination, and reduce consumable costs. Attached Figure Description

[0012] Figure 1 This is a schematic diagram of a graduated and squeezeable container for preserving human papillomavirus.

[0013] Figure 2 This is a schematic diagram of the tube structure.

[0014] Explanation of reference numerals in the attached diagram: 1. Tube body; 2. Tube cap; 3. Silicone mold; 4. Sample inlet; 5. Smooth top section; 6. External thread section; 7. Protective cover; 8. Mesh. Detailed Implementation

[0015] The technical solutions in the embodiments of this patent will be clearly and completely described below with reference to the accompanying drawings.

[0016] To address the problems of existing preservation bottles, such as inconvenience in operation, inability to remove impurities leading to failure to extract effective nucleic acids, and the fact that repeated aspiration processes cause sample contamination, increase operator workload, and raise consumable costs, a new... Figure 1 The graduated and compressible container for human papillomavirus (HPV) preservation solution shown includes a tube 1 and a cap 2 at the top of the tube 1. A key feature is the graduations on the side wall of the tube 1, allowing for easy and intuitive reading of the liquid volume. The tube 1 is made of POE-toughened LDPE. LDPE (low-density polyethylene, also known as high-pressure polyethylene, is a plastic material suitable for various thermoplastic molding processes, exhibiting good processability. LDPE is mainly used for film products, and also for injection molding, medical devices, pharmaceutical and food packaging materials, blow-molded hollow products, etc.) is a flexible tube (requiring high transparency and low hardness for easy extrusion; POE is also used in some cases; POE is an elastic composite material. POE stands for Polyolyltha Olfin: a polyvinyl octene co-elastomer, a type of POE elastic composite material). Compared to existing rigid preservation bottles, the tube can be squeezed to effectively remove impurities and mucus, facilitating the extraction of effective nucleic acids. Furthermore, [the text abruptly ends here, likely due to an incomplete translation or source material.] Figure 2As can be seen, the diameter of tube body 1 is 1cm, and tube cap 1 is an inverted cone (i.e., a pointed tip) that is fastened to the top inlet of tube body 1; and a sample inlet 4 with a diameter of 0.2cm is opened at the top of tube cap 2. The outer wall of the top opening of tube body 1 has a smooth top section 5 and an externally threaded section 6 located below the smooth top section 5. The externally threaded section 6 is used to threadedly connect to the protective cap 7 fastened to tube body 1 and tube cap 2. The length from the top of the externally threaded section 6 to the bottom of tube body 1 is 5cm. During sampling, the protective cap 7 is opened, and the liquid flows out from the sample inlet 4. After sampling, the protective cap 7 is fastened to prevent leakage. The height of the smooth top section 5 is 0.2cm; the height of the externally threaded section 6 is 1cm.

[0017] Combination Figure 2 As can be seen, a silicone mold 3 is provided at the top inlet of the tube 1, and the silicone mold 3 has multiple mesh holes 8 with a diameter range of 0.15 to 0.25 mm.

[0018] Furthermore, the optimal diameter of mesh 8 is 0.2 mm; the mesh 8 is designed to filter out cervical cells. Cervical swabs or samples submitted for testing contain many impurities, and the mesh design will intercept excessive mucus strands and other impurities.

Claims

1. A graduated and squeezeable container for preserving human papillomavirus (HPV) solution, comprising a tube (1) and a cap (2) disposed at the top of the tube (1), characterized in that, The tube body (1) has graduations on its side wall and is a flexible tube made of LDPE. A silicone mold (3) is provided at the top entrance of the tube (1), and the silicone mold (3) has multiple mesh holes (8) with a diameter range of 0.15 to 0.25 mm. The cap (2) is an inverted cone and is fastened to the top inlet of the tube body (1); The top of the cap (2) has a sample inlet (4) with a diameter of 0.2 cm.

2. The container according to claim 1, characterized in that, The outer wall of the top opening of the tube body (1) is provided with a top smooth section (5) and an external thread section (6) located below the top smooth section (5). The external thread section (6) is used to be threadedly connected to the protective cover that is fastened to the tube body (1) and the cap (2).

3. The container according to claim 2, characterized in that: The height of the smooth top section (5) is 0.2 cm; the height of the external thread section (6) is 1 cm.

4. The container according to claim 2, characterized in that, The length from the top of the external thread section (6) to the bottom of the tube body (1) is 5cm.

5. The container according to claim 1, 2, 3, or 4, characterized in that, The diameter of the tube (1) is 1 cm.

6. The container according to claim 1, 2, 3, or 4, characterized in that, The tube body (1) is made of POE-toughened LDPE.

7. The container according to claim 1, characterized in that, The diameter of the mesh (8) opened on the silicone mold (3) is 0.2 mm.

Images