Granulating device for solid preparation production

Abstract

This invention provides a granulation device for solid dosage form preparation, relating to the field of dosage form granulation technology. The granulation device includes a granulator and a hopper mounted on the granulator. A C-shaped main support is fixedly mounted on one side of the granulator. A lifting screw is rotatably mounted inside the C-shaped main support. A lifting seat is threaded onto the lifting screw. A rodless cylinder is fixedly mounted on the top of the lifting seat. A first C-shaped secondary support is located above the rodless cylinder. Vertical shifting shafts are rotatably mounted on the top and bottom inner walls of the first C-shaped secondary support. A common bearing frame is fixedly mounted at the ends of the two vertical shifting shafts that are close to each other. A transverse shifting shaft is rotatably mounted on one side of the bearing frame. This invention has the advantages of eliminating the need for repeated manual pouring of raw materials, reducing labor burden, and achieving a high degree of automation.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical granulation technology, and in particular to a granulation device for the preparation of solid dosage forms. Background Technology

[0002] Solid dosage forms are a common type of drug, including powders, granules, capsules, and tablets. The manufacturing process of solid dosage forms is mostly inseparable from granulation machines, which are devices that grind moist powder raw materials into granules. Therefore, they are often used in the preparation of drug formulations.

[0003] However, it has been found that common granulators require the powder or soft raw material to be poured into the hopper above the granulator each time granulation is performed. The hopper then guides the raw material into the granulator body for granulation. The common method of pouring material is to manually lift the material tank and put the raw material into the hopper. This method requires a lot of physical strength, and since granulation is mostly a continuous process, the pouring work needs to be repeated many times, which places a heavy workload on the workers. In addition, it is easy for raw materials to leak out due to human error, resulting in waste of raw materials.

[0004] Therefore, it is necessary to provide a new granulation apparatus for the preparation of solid dosage forms to solve the above-mentioned technical problems. Utility Model Content

[0005] The purpose of this invention is to provide a granulation device for the preparation of solid dosage forms that eliminates the need for repeated manual pouring of raw materials, reduces labor burden, and has a high degree of automation.

[0006] To solve the above-mentioned technical problems, the granulation device for solid dosage form preparation provided by this utility model includes: a granulator and a hopper disposed on the granulator. A C-shaped main support is fixedly installed on one side of the granulator. A lifting screw is rotatably installed inside the C-shaped main support. A lifting seat is threaded onto the lifting screw. A rodless cylinder is fixedly installed on the top of the lifting seat. A first C-shaped secondary support is provided above the rodless cylinder. Vertical shifting shafts are rotatably installed on the top and bottom inner walls of the first C-shaped secondary support. The ends of the two vertical shifting shafts that are close to each other are fixed. A common support frame is installed, and a transverse shifting shaft is rotatably installed on one side of the support frame. A main loading plate is fixedly installed at one end of the transverse shifting shaft. A second C-shaped sub-support is fixedly installed on the side of the main loading plate away from the support frame. An adjusting screw is rotatably installed inside the second C-shaped sub-support. A bearing seat is threaded onto the adjusting screw. A storage trough is opened on the top of the bearing seat. A storage tank is placed in the storage trough. A positioning plate is fixedly installed on the side of the main loading plate away from the support frame. The positioning plate is in contact with the top of the storage tank.

[0007] Preferably, a connecting platform is fixedly installed on the slider of the rodless cylinder, and the top of the connecting platform is fixedly connected to the first C-shaped sub-support.

[0008] Preferably, the top end of the lifting screw extends above the C-shaped main body support, and a first reduction motor is fixedly installed on one outer wall of the C-shaped main body support. Synchronous pulleys are fixedly sleeved on the output shaft of the first reduction motor and the lifting screw, and the same synchronous belt is sleeved on the two synchronous pulleys.

[0009] Preferably, a second geared motor is fixedly installed on the top of the first C-shaped sub-support, and the output shaft of the second geared motor is fixedly connected to the top end of the vertical shifting shaft located above. A third geared motor is fixedly installed on the top of the second C-shaped sub-support, and the output shaft of the third geared motor is fixedly connected to the top end of the adjusting screw.

[0010] Preferably, a discharge pipe is fixedly installed on the top of the storage tank, the discharge pipe is adapted to the hopper, and an open slot is opened on the side of the positioning plate away from the main loading plate, the discharge pipe is located in the open slot and contacts the inner wall of the open slot.

[0011] Preferably, a fourth reduction motor is fixedly installed inside the bearing frame, and the output shaft of the fourth reduction motor is fixedly connected to one end of the transverse shifting shaft. A T-shaped stabilizing ring groove is provided on the side of the bearing frame near the main loading plate, and two T-shaped stabilizing rods are slidably installed in the T-shaped stabilizing ring groove. The ends of the two T-shaped stabilizing rods near the storage tank are fixedly connected to the main loading plate.

[0012] Preferably, the discharge pipe is equipped with an electric material valve.

[0013] Compared with related technologies, the granulation device for solid dosage form preparation provided by this utility model has the following beneficial effects:

[0014] This invention provides a granulation device for solid dosage form preparation. With the addition of a lifting seat, a vertical shifting shaft, a horizontal shifting shaft, and a storage tank, the raw materials in the storage tank can be automatically fed into the hopper, thus achieving a high degree of automation in the material feeding process. The entire process only requires manual fixing of the storage tank in the settling trough, eliminating the need for repeated manual feeding and significantly reducing the labor intensity of workers. Attached Figure Description

[0015] Figure 1 A schematic diagram of a preferred embodiment of the granulation apparatus for preparing solid dosage forms provided by this utility model;

[0016] Figure 2 This is a schematic diagram of the connection structure between the rodless cylinder and the connecting platform in this utility model;

[0017] Figure 3 This is a schematic diagram of the connection structure between the vertical transposition shaft and the bearing frame in this utility model;

[0018] Figure 4 This is a schematic diagram of the transverse transposition shaft in this utility model;

[0019] Figure 5 This is a schematic diagram of the placement of the sedimentation tank in this utility model.

[0020] Labels in the diagram: 1. Pelletizer; 2. Hopper; 3. C-shaped main support; 4. Lifting screw; 5. Lifting seat; 6. Rodless cylinder; 7. Connecting platform; 8. First C-shaped secondary support; 9. Vertical shifting shaft; 10. Bearing frame; 11. Horizontal shifting shaft; 12. Loading main plate; 13. Second C-shaped secondary support; 14. Adjusting screw; 15. Bearing seat; 16. Loading trough; 17. Storage tank; 18. Discharge pipe; 19. Positioning plate; 20. Open slot. Detailed Implementation

[0021] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0022] Please refer to the following: Figures 1-5 ,in, Figure 1 A schematic diagram of a preferred embodiment of the granulation apparatus for preparing solid dosage forms provided by this utility model; Figure 2 This is a schematic diagram of the connection structure between the rodless cylinder and the connecting platform in this utility model; Figure 3 This is a schematic diagram of the connection structure between the vertical transposition shaft and the bearing frame in this utility model; Figure 4 This is a schematic diagram of the transverse transposition shaft in this utility model; Figure 5 This is a schematic diagram of the placement of the sedimentation tank in this utility model.

[0023] The granulation apparatus for solid dosage form preparation includes a granulator 1 and a hopper 2 mounted on the granulator 1. The granulator 1 is a common granulation device on the market, possessing the basic functions expected of a granulation device, which will not be elaborated upon here. A U-shaped main support 3 is fixedly installed on one side of the granulator 1, and a lifting screw 4 is rotatably mounted inside it. To drive the lifting screw 4 to rotate, the top end of the lifting screw 4 extends above the U-shaped main support 3. A first reduction motor is fixedly installed on the outer wall of one side of the U-shaped main support 3. Synchronous pulleys are fixedly fitted on both the output shaft of the motor and the lifting screw 4, and the same synchronous belt is fitted on the two synchronous pulleys. A lifting seat 5 is threaded onto the lifting screw 4, and two guide columns are fixed inside the C-shaped main support 3. Both guide columns penetrate the lifting seat 5 and are slidably connected to it. A rodless cylinder 6 is fixedly installed on the top of the lifting seat 5. A connecting platform 7 is fixedly installed on the slider of the rodless cylinder 6, and a first C-shaped secondary support 8 is fixedly installed on the top of the connecting platform 7. Vertical shifting shafts 9 are rotatably installed on the top and bottom inner walls of the first C-shaped secondary support 8. The same bearing frame 10 is fixedly installed at the ends of the two vertical shifting shafts 9 that are close to each other. A second reduction motor is fixedly installed on the top of the first C-shaped secondary support 8, and its output shaft... The vertical shifting shaft 9 located above is fixedly connected to its top end, thus driving the vertical shifting shaft 9 to rotate. A horizontal shifting shaft 11 is rotatably mounted on one side of the support frame 10. At the same time, a fourth geared motor is fixedly mounted inside the support frame 10, and its output shaft is fixedly connected to one end of the horizontal shifting shaft 11. A load-bearing main plate 12 is fixedly mounted on one end of the horizontal shifting shaft 11. A second U-shaped sub-support 13 is fixedly mounted on the side of the load-bearing main plate 12 away from the support frame 10, and an adjusting screw 14 is rotatably mounted inside it. A third geared motor is fixedly mounted on the top of the second U-shaped sub-support 13, and its output shaft is fixedly connected to the top end of the adjusting screw 14. A bearing seat 15 is threaded onto the adjusting screw 14. A storage trough 16 is provided on the top of the bearing seat 15. A storage tank 17 is placed in the storage trough 16. A discharge pipe 18 is fixedly installed on the top of the storage tank 17. The discharge pipe 18 is adapted to the hopper 2 and is equipped with an electric material valve. A positioning plate 19 is fixedly installed on the side of the main bearing plate 12 away from the bearing frame 10. The positioning plate 19 is in contact with the top of the storage tank 17. By starting the fourth reduction motor, the storage tank 17 can be rotated, so that the discharge pipe 18 changes from an upward position to a downward position, thereby allowing the raw materials in the storage tank 17 to be poured out.

[0024] In the above method, in order to fix the storage tank 17 and enable it to rotate smoothly, an open slot 20 is provided on the side of the positioning plate 19 away from the main loading plate 12. The discharge pipe 18 is located in the open slot 20 and contacts the inner wall of the open slot 20. The open slot 20 provides space for the discharge pipe 18, thereby enabling the storage tank 17 to be installed and fixed.

[0025] In this method, in order to ensure the stability of the main board 12 during rotation, a T-shaped stabilizing ring groove is provided on the side of the support frame 10 near the main board 12. Two T-shaped stabilizing rods are slidably installed in the T-shaped stabilizing ring groove, and the ends of the two T-shaped stabilizing rods near the storage tank 17 are fixedly connected to the main board 12.

[0026] The working principle of the granulation device for solid dosage form preparation provided by this utility model is as follows:

[0027] In this device, the number of storage tanks 17 is set in advance, and each storage tank 17 contains pharmaceutical raw materials;

[0028] When it is necessary to pour the raw materials of the preparation into the granulator 1 for granulation, the first geared motor is started directly in the forward direction. Its output shaft drives the lifting screw 4 to rotate, so that the lifting seat 5 starts to rise. After the lifting seat 5 rises to the highest position, the fourth geared motor is started in the forward direction. Its output shaft drives the transverse shifting shaft 11 to rotate. At this time, the storage tank 17 also rotates. After the storage tank 17 rotates 180°, the discharge pipe 18 faces downward. Then, the second geared motor is started in the forward direction. Its output shaft drives the corresponding vertical shifting shaft 9 to rotate. With the support frame 10, the two vertical shifting shafts 9 rotate together with the support frame 10. After the support frame 10 rotates 180°, the storage tank 17 rotates from the previous side to the other side.

[0029] Then, start the rodless cylinder 6, and the slider on it moves the connecting platform 7 towards the hopper 2, which in turn moves the storage tank 17 together. Finally, bring the storage tank 17 directly above the hopper 2, and then open the electric material valve on the discharge pipe 18. The raw material in the storage tank 17 will then fall down and into the pellet mill 1 through the hopper 2. After a certain amount of raw material has fallen in, the electric material valve can be closed, and then the pellet mill 1 can be started to granulate.

[0030] After each batch of pelleting is completed, the electric feed valve is reopened to continue feeding, thus enabling the pelleting process to continue.

[0031] In subsequent use, when the raw materials in storage tank 17 are used up, the second reduction motor is first started in reverse to bring storage tank 17 back to its original position. Then, the fourth reduction motor is started in reverse to rotate storage tank 17 180° so that the discharge pipe 18 faces upward and returns to its original state. Then, the first reduction motor is started in reverse, and the lifting seat 5 lowers storage tank 17. After it descends to the original point, it first supports the empty storage tank 17. Then, the third reduction motor is started in the forward direction. Its output shaft drives the adjusting screw 14 to rotate, and the bearing seat 15 on it begins to descend. Finally, it completely separates from storage tank 17, and then storage tank 17 can be directly pulled out. Then, the discharge pipe 18 on the next storage tank 17 containing raw materials is inserted back into the open slot 20, and the top of the storage tank 17 contacts the bottom of the positioning plate 19. Then, the third reduction motor is started in reverse to make storage tank 17 re-enter the storage trough 16.

[0032] Compared with related technologies, the granulation device for solid dosage form preparation provided by this utility model has the following beneficial effects:

[0033] This utility model provides a granulation device for the preparation of solid dosage forms. With the lifting seat 5, vertical shifting shaft 9, horizontal shifting shaft 11 and storage tank 17, the raw materials in the storage tank 17 can be automatically fed into the hopper 2, thereby realizing a high degree of automation in the material feeding process. The entire process only requires manual fixing of the storage tank 17 in the settling trough 16, eliminating the need for repeated manual feeding, thus greatly reducing the labor intensity of the workers.

[0034] The above description is merely an embodiment of this utility model and does not limit the patent scope of this utility model. Any equivalent structural or procedural transformations made based on the content of this utility model specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this utility model.

Claims

1. A granulating device for solid preparation production, comprising a granulator and a hopper provided on the granulator, characterized in that, A C-shaped main support is fixedly installed on one side of the granulator. A lifting screw is rotatably installed inside the C-shaped main support. A lifting seat is threaded onto the lifting screw. A rodless cylinder is fixedly installed on the top of the lifting seat. A first C-shaped secondary support is provided above the rodless cylinder. Vertical shifting shafts are rotatably installed on the top and bottom inner walls of the first C-shaped secondary support. The same bearing frame is fixedly installed at the ends of the two vertical shifting shafts that are close to each other. A transverse shifting shaft is rotatably installed on one side of the bearing frame. A loading main plate is fixedly installed at one end of the transverse shifting shaft. A second C-shaped secondary support is fixedly installed on the side of the loading main plate away from the bearing frame. An adjusting screw is rotatably installed inside the second C-shaped secondary support. A bearing seat is threaded onto the adjusting screw. A storage trough is opened on the top of the bearing seat. A storage tank is placed in the storage trough. A positioning plate is fixedly installed on the side of the loading main plate away from the bearing frame. The positioning plate is in contact with the top of the storage tank.

2. The granulating apparatus for solid preparation production according to claim 1, wherein A connecting platform is fixedly installed on the slider of the rodless cylinder, and the top of the connecting platform is fixedly connected to the first C-shaped sub-support.

3. The granulating apparatus for solid preparation according to claim 1, wherein The top of the lifting screw extends above the C-shaped main support. A first reduction motor is fixedly installed on one outer wall of the C-shaped main support. Synchronous pulleys are fixedly sleeved on the output shaft of the first reduction motor and the lifting screw. The same synchronous belt is sleeved on the two synchronous pulleys.

4. The granulating apparatus for solid preparation according to claim 1, wherein A second geared motor is fixedly installed on the top of the first C-shaped sub-support. The output shaft of the second geared motor is fixedly connected to the top end of the vertical shifting shaft located above. A third geared motor is fixedly installed on the top of the second C-shaped sub-support. The output shaft of the third geared motor is fixedly connected to the top end of the adjusting screw.

5. The granulating apparatus for solid preparation according to claim 1, wherein A discharge pipe is fixedly installed on the top of the storage tank. The discharge pipe is adapted to the hopper. An open slot is opened on the side of the positioning plate away from the main loading plate. The discharge pipe is located in the open slot and contacts the inner wall of the open slot.

6. The granulating apparatus for solid preparation according to claim 1, wherein A fourth reduction motor is fixedly installed inside the bearing frame. The output shaft of the fourth reduction motor is fixedly connected to one end of the transverse shifting shaft. A T-shaped stabilizing ring groove is provided on the side of the bearing frame near the main loading plate. Two T-shaped stabilizing rods are slidably installed in the T-shaped stabilizing ring groove. The ends of the two T-shaped stabilizing rods near the storage tank are fixedly connected to the main loading plate.

7. The granulating apparatus for solid preparation production according to claim 5, wherein The discharge pipe is equipped with an electric material valve.

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