Multistage centrifugal separation device for bilirubin extraction

Abstract

The utility model discloses a multistage centrifugal separation device for bilirubin extraction belongs to bilirubin extraction technical field, including separation box body, detachable setting the box cover of separation box body top, rotatory setting rotatory board of box cover bottom wall, detachable setting the filter vat of multiple coaxial settings of rotatory board bottom wall, hollow rotating shaft vertically through setting between box cover with rotatory board, the feed pipe of movable setting in hollow rotating shaft and bottom end extension to the inside filter vat of most, and drive hollow rotating shaft rotates the drive assembly of, multiple filter vat same bottom wall, the filter hole aperture of multiple filter vat reduces gradually from inside to outside, the filter hole aperture of each filter vat bottom wall and the filter hole aperture of outermost layer are same. The device can realize multistage centrifugal separation, improve centrifugal efficiency, and can dismantle filter vat after centrifugation to clean and wash filter vat.

Description

Technical Field

[0001] This utility model relates to the field of bilirubin extraction technology, and in particular to a multi-stage centrifugal separation device for bilirubin extraction. Background Technology

[0002] In the biomedical field, bilirubin, as an important endogenous antioxidant, is widely used in the treatment of neonatal jaundice and the development of anti-tumor drugs. Bilirubin is extracted from animal bile. During the pretreatment stage of animal bile, fresh bile may contain some large solid impurities and flocculent matter, which need to be removed to avoid these impurities affecting subsequent extraction reactions.

[0003] Currently, single-stage centrifugation is commonly used to separate impurities in fresh bile. However, single-stage centrifugation cannot achieve fine separation of particles of different sizes in a single operation, leading to a decrease in bilirubin purity. Furthermore, in existing technologies, the filter assembly and the centrifuge body are usually integrated, making it difficult to replace the filter assembly in a timely manner.

[0004] Therefore, there is an urgent need for a multi-stage centrifugal separation device that can significantly improve separation efficiency and facilitate the replacement of filter components. Utility Model Content

[0005] The purpose of this invention is to provide a multi-stage centrifugal separation device for bilirubin extraction. This device can achieve multi-stage centrifugal separation, improve centrifugation efficiency, and allow the filter cartridge to be disassembled after centrifugation for easy cleaning and washing.

[0006] The objective of this utility model is achieved through the following technical solution:

[0007] A multi-stage centrifugal separation device for bilirubin extraction includes a separation chamber, a cover detachably disposed at the top of the separation chamber, a rotating plate rotatably disposed on the bottom wall of the cover, a plurality of coaxially arranged filter barrels detachably disposed on the bottom wall of the rotating plate, a hollow rotating shaft vertically passing between the cover and the rotating plate, a feed pipe movably disposed within the hollow rotating shaft and extending to the innermost filter barrel at its bottom end, and a drive assembly for driving the hollow rotating shaft to rotate.

[0008] The multiple filter barrels have the same bottom wall, and the pore diameter of the multiple filter barrels decreases sequentially from the inside to the outside; the pore diameter of the bottom wall of each filter barrel is the same as the pore diameter of the outermost layer of filter holes.

[0009] Preferably, the drive assembly includes a motor disposed above the housing cover, a first gear sleeved on the output end of the motor, and a second gear sleeved on the outside of the hollow rotating shaft and meshing with the first gear.

[0010] Preferably, a connecting ring is provided around the outer edge of the top of the outermost filter barrel, and the connecting ring and the rotating plate are connected by bolts.

[0011] Preferably, the lid and the separation box are threaded together.

[0012] Preferably, the top of the box cover is provided with an annular air duct, and the bottom end of the annular air duct is provided with multiple branch pipes vertically, the bottom ends of the branch pipes all passing through the rotating plate and communicating with the interior of the separation box; the annular air duct is also connected to an air inlet pipe, and the air inlet end of the air inlet pipe is connected to a hot air blower provided on the box cover.

[0013] Preferably, the side wall of the feed pipe is provided with multiple discharge holes, and the bottom end of the feed pipe is threadedly connected to a bottom cover.

[0014] Preferably, the side wall of the separation chamber is provided with a transparent observation window.

[0015] Preferably, the bottom wall of the separation box is provided with a discharge pipe, and the bottom wall of the separation box is inclined downward along the direction of the discharge pipe.

[0016] Preferably, the feed pipe is externally threaded with a retaining ring, which is fixedly mounted on the top of the box cover by a retaining rod.

[0017] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0018] By using a multi-layered coaxial screen, continuous multi-stage separation can be achieved within a single device, effectively improving the centrifugal separation efficiency of materials.

[0019] By incorporating a feed pipe that moves within the hollow rotating shaft, centrifugation can be performed simultaneously with feeding, thereby improving feeding efficiency and ensuring continuous feeding, achieving continuous centrifugal separation, and enhancing separation efficiency.

[0020] By making the filter bucket and the rotating plate detachably connected, and the cover and the separation chamber detachably connected, the cover can be removed after centrifugation, and then the filter bucket can be removed from the rotating plate, thereby achieving the purpose of cleaning and washing the filter bucket. Attached Figure Description

[0021] Figure 1 This is a cross-sectional view of Example 1 from the front view.

[0022] Figure 2 for Figure 1 A schematic diagram of the cross-sectional structure of the middle filter barrel from a top view.

[0023] Figure 3 This is a structural schematic diagram of the box lid viewed from above.

[0024] In the diagram: 1-Separation box, 2-Box cover, 3-Rotating plate, 4-Filter barrel, 5-Hollow rotating shaft, 6-Motor, 7-First gear, 8-Second gear, 9-Connecting ring, 10-Bolt, 11-Annular air duct, 12-Branch pipe, 13-Air inlet pipe, 14-Hot air blower, 15-Feed pipe, 16-Bottom cover, 18-Observation window, 17-Discharge pipe, 19-Fixing ring, 20-Fixing rod. Detailed Implementation

[0025] Example 1

[0026] A multi-stage centrifugal separation device for bilirubin extraction, such as Figures 1-3 As shown, the assembly includes a separation chamber 1, a cover 2 detachably mounted on the top of the separation chamber 1, a rotating plate 3 rotatably mounted on the bottom wall of the cover 2, multiple coaxially mounted filter barrels 4 (the multiple filter barrels 4 are integrated and are referred to as filter barrel assemblies) detachably mounted on the bottom wall of the rotating plate 3, a hollow rotating shaft 5 vertically passing between the cover 2 and the rotating plate 3, a feed pipe 15 movably mounted inside the hollow rotating shaft 5 and extending to the innermost filter barrel 4 at its bottom end, and a drive assembly for driving the hollow rotating shaft 5 to rotate.

[0027] like Figure 1 As shown, the multiple filter barrels 4 have the same bottom wall, and the diameter of the filter holes (the filter holes are existing technology and are not shown in the figure) of the multiple filter barrels 4 decreases from the inside to the outside; the diameter of the filter holes on the bottom wall of each filter barrel 4 is the same as the diameter of the outermost filter hole.

[0028] Furthermore, such as Figure 1 and Figure 3 As shown, the drive assembly includes a motor 6 disposed above the cover 2, a first gear 7 sleeved on the output end of the motor 6, and a second gear 8 sleeved on the outside of the hollow rotating shaft 5 and meshing with the first gear 7.

[0029] Furthermore, such as Figure 1-2 As shown, the outermost filter barrel 4 has a connecting ring 9 around its top outer edge, and the connecting ring 9 and the rotating plate 3 are connected by bolts 10.

[0030] Furthermore, the cover 2 and the separation box 1 are threaded together.

[0031] Furthermore, such as Figure 1 As shown, the bottom wall of the separation box 1 is provided with a discharge pipe 17, and the bottom wall of the separation box 1 is inclined downward along the direction of the discharge pipe 17.

[0032] Furthermore, such as Figure 1 and Figure 3As shown, the feed pipe 15 is externally threaded with a fixing ring 19, which is fixedly mounted on the top of the box cover 2 by a fixing rod 20.

[0033] Working principle: Fresh bile enters the innermost filter barrel 4 through the feed pipe 15. The motor 6 drives the first gear 7 to rotate, which in turn drives the second gear 8 to rotate, so that the filter barrel assembly rotates synchronously. During the rotation, impurities in the fresh bile are blocked by the multiple filter barrels 4 in the filter barrel assembly under the action of centrifugal force. The filtrate after separation is finally collected at the bottom of the separation box 1 along the outermost filter barrel 4 and the bottom wall of the filter barrel 4. Depending on the actual needs, it can be discharged along the discharge pipe 17 (a valve is installed on the storage tank, which is not shown in the figure).

[0034] During the centrifugation process, the feed can be continuously added through the feed pipe 15 to ensure the continuity of centrifugation.

[0035] After centrifugation is complete, remove the cover 2 from the top of the separation chamber 1, then remove the bolt 10, and then remove the filter assembly from the rotating plate 3. After that, it can be cleaned or washed.

[0036] Example 2

[0037] In Example 1, after cleaning the filter assembly and the separation chamber 1, both need to be dried to prevent corrosion of components caused by prolonged exposure to a humid environment. Therefore, based on Example 1, as follows... Figure 1-3 As shown, a ring-shaped air duct 11 is provided at the top of the cover 2, and multiple branch pipes 12 are vertically arranged at the bottom of the ring-shaped air duct 11. The bottom ends of the branch pipes 12 all pass through the rotating plate 3 and communicate with the interior of the separation chamber 1. The ring-shaped air duct 11 is also connected to the air inlet pipe 13, and the air inlet end of the air inlet pipe 13 is connected to the hot air blower 14 provided on the cover 2. In this embodiment, after the filter assembly and the separation chamber 1 are cleaned, the filter assembly is installed at the bottom of the rotating plate 3, and the cover 2 is installed at the top of the separation chamber 1. Then, the hot air blower 14 is turned on, so that hot air enters the separation chamber 1 along the air inlet pipe 13, the ring-shaped air duct 11, and the multiple branch pipes 12 to achieve the purpose of quickly drying the separation device. During drying, the discharge pipe 17 needs to be unobstructed and the feed pipe 15 needs to be closed, so that the hot air can be distributed throughout the entire separation chamber 1, improving the drying efficiency.

[0038] Furthermore, because the filter holes on the bottom wall of the filter assembly and the filter holes on the outermost filter barrel 4 have the same diameter, the pore size is relatively small. If fresh bile falls directly into the bottom wall of the filter barrel 4, it will cause rapid blockage of the bottom wall, thus affecting the subsequent filtration efficiency. Based on this, the side wall of the feed pipe 15 is provided with multiple discharge holes (existing technology, not shown in the figure), such as... Figure 1As shown, the bottom end of the feed pipe 15 is threadedly connected to a bottom cover 16. By setting the bottom cover 16, fresh bile can be prevented from falling directly onto the bottom wall of the sieve barrel. By setting multiple discharge holes, fresh bile can be splashed onto the side wall of the filter barrel 4 along the multiple discharge holes. The diameter of the holes on the innermost sieve barrel side wall is relatively large, which can effectively alleviate the problem of clogging.

[0039] Furthermore, such as Figure 1 As shown, the side wall of the separation chamber 1 is provided with a transparent observation window 18. This allows for easy monitoring of the filtration process within the separation chamber 1, particularly the storage of filtrate at the bottom of the separation chamber 1. When there is too much filtrate, it can be removed promptly to ensure that the filtrate remains below the filter assembly.

Claims

1. A multi-stage centrifugal separation device for bilirubin extraction, characterized in that, The device includes a separation box (1), a box cover (2) detachably disposed at the top of the separation box (1), a rotating plate (3) rotatably disposed at the bottom wall of the box cover (2), a plurality of coaxially disposed filter barrels (4) detachably disposed at the bottom wall of the rotating plate (3), a hollow rotating shaft (5) vertically disposed between the box cover (2) and the rotating plate (3), a feed pipe (15) movably disposed in the hollow rotating shaft (5) and extending to the innermost filter barrel (4) at its bottom end, and a drive assembly for driving the hollow rotating shaft (5) to rotate. Multiple filter barrels (4) have the same bottom wall, and the filter hole diameter of the multiple filter barrels (4) decreases sequentially from the inside to the outside; the filter hole diameter of the bottom wall of each filter barrel (4) is the same as the outermost filter hole diameter.

2. The multi-stage centrifugal separation device for bilirubin extraction according to claim 1, characterized in that, The drive assembly includes a motor (6) disposed above the cover (2), a first gear (7) sleeved on the output end of the motor (6), and a second gear (8) sleeved on the outside of the hollow shaft (5) and meshing with the first gear (7).

3. The multi-stage centrifugal separation device for bilirubin extraction according to claim 1, characterized in that, The outermost filter barrel (4) has a connecting ring (9) around its top outer edge, and the connecting ring (9) and the rotating plate (3) are connected by bolts (10).

4. The multi-stage centrifugal separation device for bilirubin extraction according to claim 1, characterized in that, The cover (2) and the separation box (1) are threaded together.

5. The multi-stage centrifugal separation device for bilirubin extraction according to claim 1, characterized in that, The top of the box cover (2) is provided with a ring-shaped air duct (11), and the bottom end of the ring-shaped air duct (11) is provided with multiple branch pipes (12). The bottom ends of the branch pipes (12) all pass through the rotating plate (3) and are connected to the interior of the separation box (1). The ring-shaped air duct (11) is also connected to the air inlet pipe (13), and the air inlet end of the air inlet pipe (13) is connected to the hot air blower (14) provided on the box cover (2).

6. The multi-stage centrifugal separation device for bilirubin extraction according to claim 1, characterized in that, The feed pipe (15) has multiple discharge holes on its side wall, and the bottom end of the feed pipe (15) is threadedly connected to a bottom cover (16).

7. The multi-stage centrifugal separation device for bilirubin extraction according to claim 1, characterized in that, The side wall of the separation box (1) is provided with a transparent observation window (18).

8. The multi-stage centrifugal separation device for bilirubin extraction according to claim 1, characterized in that, The bottom wall of the separation box (1) is provided with a discharge pipe (17), and the bottom wall of the separation box (1) is inclined downward along the direction of the discharge pipe (17).

9. The multi-stage centrifugal separation device for bilirubin extraction according to claim 1, characterized in that, The feed pipe (15) is externally threaded with a fixing ring (19), which is fixedly mounted on the top of the box cover (2) by a fixing rod (20).

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