A protective bottle jacket for preventing mannitol crystallization in winter
By designing a heat source chamber, a bottle insulation sleeve, and a heat transfer plate protective sleeve, and utilizing reaction filler and paraffin phase change material, the problem of mannitol crystallization at low temperatures was solved, effectively preventing crystallization in winter and out-of-hospital emergency care, and providing a convenient and reusable solution.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- BEIJING ANZHEN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
- Filing Date
- 2025-04-04
- Publication Date
- 2026-07-24
AI Technical Summary
Mannitol is prone to crystallization at low temperatures, and existing technologies are not very effective in preventing crystallization, especially in out-of-hospital emergency care.
A protective bottle sleeve was designed, comprising a heat source chamber, a bottle insulation sleeve, a heat transfer plate, and a honeycomb insulation sleeve. Heat is generated by the reaction filling and water bag in the heat source chamber and conducted to the bottle body through the heat transfer plate. Combined with paraffin phase change material, a constant temperature is maintained to prevent mannitol crystallization.
It effectively prevents mannitol crystallization in winter and out-of-hospital emergency conditions, provides a convenient and reusable solution, ensures that the temperature of the solution is within a safe range, and is suitable for hospital and emergency scenarios.
Smart Images

Figure CN224540694U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of medical auxiliary materials technology, and in particular to a protective bottle sleeve to prevent mannitol crystallization in winter. Background Technology
[0002] Mannitol is commonly used clinically to lower intracranial pressure, reduce intraocular pressure, and promote renal excretion. Mannitol is prone to crystallization during use and storage, especially at low temperatures or high concentrations. Crystallization may affect drug infusion and product stability.
[0003] Mannitol is commonly stored in a high-temperature chamber. However, there are two ways to prevent crystallization in clinical use. The first is to heat the infusion tube, but the temperature of the plastic tube is not easy to control. The second is external heating, which may lead to recrystallization in the later stages of use. Especially in out-of-hospital emergency care, there is not a very good way to prevent crystallization. Utility Model Content
[0004] The purpose of this utility model is to provide a protective bottle sleeve to prevent mannitol crystallization in winter. It has the advantages of being easy to remove and use, suitable for outdoor emergency use and hospital use, and can be reused multiple times, with low cost.
[0005] To achieve the above objectives, this utility model provides the following technical solution: a protective bottle sleeve to prevent mannitol crystallization in winter, comprising: The heat source chamber includes a protective sleeve for placing the reaction filling material and a fixed cover detachably connected to the protective sleeve. A water bag is attached to the cavity of the fixed cover. A needle head is provided on the axis of the protective sleeve and is slid on the needle head by a pressure plate, thereby exposing the tip of the needle head. The bottle insulation sleeve is detachably connected to the heat source chamber, and the inner diameter of the bottle insulation sleeve is adapted to the size of the mannitol bottle. The bottom of the bottle insulation sleeve is provided with a neck restraint part, which includes two specifications: long and short. It is mainly made of soft silicone or elastic textile material and is used to wrap around the neck of the mannitol bottle. Its main function is that the neck restraint part can be opened manually to quickly replace the mannitol bottle. A heat transfer plate is fixedly connected to the inner cavity of the heat source chamber, and the insertion part extends downward from inside the heat source chamber and bends outward to form an outward expansion shape. The bottle insulation sleeve is suspended from the reverse hook provided on the insertion part.
[0006] Furthermore, the fixing cover includes an annular fixing part and a central circular part, which are connected by an annular silicone. The water bag is attached to the central circular part. An outer ring insert is fixedly connected to the bottom of the annular fixing part, and an inner insert is fixedly connected to the bottom of the central circular part.
[0007] Furthermore, the protective sleeve is provided with an inner chamber for placing the reaction filler. The inner chamber is supported by a metal material, and a heat-bearing plate is fixedly connected to the inner wall of the inner chamber. An insulation plate is fixedly connected to the bottom inner cavity of the protective sleeve.
[0008] Furthermore, the top of the protective sleeve is provided with an isolation cavity, which is a vacuum chamber. A pressure ring is provided inside the isolation cavity, and multiple embedded beads are embedded in the top of the pressure ring.
[0009] Furthermore, the heat transfer plate is provided with an arc-shaped plate that fits against the outer wall of the inner cavity at one end of the heat source chamber, and a conductive strip is provided on the outside of the arc-shaped plate. The conductive strip and the arc-shaped plate are integrally formed to form the heat transfer plate.
[0010] Furthermore, the heat transfer plate comprises one or two of quicklime, magnesium powder, iron powder, salt, and bentonite or diatomaceous earth.
[0011] Furthermore, the heating jacket is provided with a honeycomb-shaped heat insulation sleeve on the outside and a heat insulation layer on the inside. Regarding the heating jacket, the honeycomb-shaped heat insulation sleeve is used to block internal heat while allowing the conducted heat to quickly disappear on the surface. When medical staff hold it, the heat they feel is below a safe temperature. Moreover, when holding it, medical staff may wear protective gloves, which have low friction. The honeycomb structure of the heat insulation sleeve increases safety during the holding process. As for the heat insulation layer, it can be a common heat insulation material, such as foam cotton.
[0012] Furthermore, the bottle label portion includes an insulation portion, the inner side of which is provided with a heat-retaining sleeve, and an internal metal plate is provided inside the heat-retaining sleeve. The internal metal plate has evenly distributed chambers, and the chambers are filled with paraffin wax. An insertion port is provided at the heat-retaining sleeve, and the insertion portion is inserted into the insertion port. Regarding the bottle label portion, it is suspended on a reverse hook by a hook rope. During use, the heat source chamber and the heating sleeve remain separate, meaning that it can be replaced individually, or a separate heating sleeve can be used. In this case, it can be suspended on a water rack by a hook rope. The specific usage is as follows.
[0013] Furthermore, the heating sleeve is provided with a hook rope, which is hung on a reverse hook.
[0014] The technical effects and advantages of this utility model are as follows: 1. This thermal cover can be used for emergency care both inside and outside hospitals. It is equipped with a rapid heating element. When used for emergency care outside hospitals, after the bottle is filled, the water comes into contact with the reaction filler. The heat generated is quickly conducted to the internal metal plate, causing the paraffin wax to melt. After the paraffin wax melts, it can maintain a constant temperature for a long time. It is convenient to use and can be used as needed.
[0015] 2. The neck restraint part comes in two specifications, long and short, and is mainly made of soft silicone or elastic textile material. It is used to wrap around the neck of the mannitol bottle. Its main function is to allow the neck restraint part to be opened manually, so that the mannitol bottle can be replaced quickly.
[0016] 3. The honeycomb heat insulation sleeve is used to block internal heat while allowing the conducted heat to quickly dissipate on the surface. When medical staff hold it, the heat they feel is below a safe temperature. In addition, medical staff may wear protective gloves during the holding process. Protective gloves have low friction. The honeycomb structure of the heat insulation sleeve increases the safety during the holding process. Attached Figure Description
[0017] Figure 1 This is a perspective view of the present invention with the long bottleneck restraint portion; Figure 2 This is a perspective view of the present invention with the short bottleneck restraint portion; Figure 3 This is a cross-sectional view of the heat source chamber in this utility model; Figure 4 This utility model Figure 3 Enlarged view of point A in the middle; Figure 5 This is a cross-sectional view of the present invention; Figure 6 This is a cross-sectional view of the present invention with an insertion port; Figure 7 This is a schematic diagram of the built-in metal plate in this utility model.
[0018] In the picture: 1. Heat source chamber; 11. Fixing cover; 12. Water bag; 13. Protective sleeve; 14. Reaction packing; 15. Needle head; 16. Pressure plate; 17. Heat-bearing plate; 18. Inner chamber; 19. Pressure ring; 110. Embedded bead; 111. Outer ring insert; 112. Inner insert; 2. Heating sleeve; 3. Bottle neck restraint part; 4. Heat transfer plate; 41. Insertion part; 42. Reverse hook; 5. Insulation plate; 6. Bottle label part; 61. Heat preservation part; 62. Heat-gathering sleeve; 63. Insertion port; 64. Internal metal plate; 65. Hole; 66. Paraffin wax; 7. Hook rope. Detailed Implementation
[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0020] Reference Figures 1 to 7 The protective bottle sleeve shown here for preventing mannitol crystallization in winter includes: The heat source chamber 1 includes a protective sleeve 13 for placing the reaction packing 14, and a fixed cover 11 detachably connected to the protective sleeve 13. A water bag 12 is attached to the cavity of the fixed cover 11. A needle head 15 is provided on the axis of the protective sleeve 13 and slides on the needle head 15 by a pressure plate 16, so that the tip of the needle head 15 is exposed. The bottle insulation sleeve is detachably connected to the heat source chamber 1, and the inner diameter of the bottle insulation sleeve is adapted to the size of the mannitol bottle. The bottom of the bottle insulation sleeve is provided with a neck restraint part 3. The heat transfer plate 4 is fixedly connected to the inner cavity of the heat source chamber 1, and the insertion part 41 extends downward from the heat source chamber 1 and forms a bent and outward shape. The bottle insulation sleeve is suspended at the reverse hook 42 provided on the insertion part 41.
[0021] The fixing cover 11 includes an annular fixing part and a central circular part. The annular fixing part and the central circular part are connected by an annular silicone. The water bag 12 is attached to the central circular part. An outer ring insert 111 is fixedly connected to the bottom of the annular fixing part, and an inner insert 112 is fixedly connected to the bottom of the central circular part.
[0022] The protective sleeve 13 has an inner chamber 18 for placing the reaction packing 14. The inner chamber 18 is supported by a metal material. The inner wall of the inner chamber 18 is fixedly connected to a heat-bearing plate 17. The bottom inner cavity of the protective sleeve 13 is fixedly connected to an insulation plate 5.
[0023] The top of the protective sleeve 13 is also provided with an isolation cavity, which is a vacuum setting. A pressure ring 19 is provided inside the isolation cavity, and multiple embedded beads 110 are embedded on the top of the pressure ring 19.
[0024] The heat transfer plate 4 is located at one end of the heat source chamber 1 and is provided with an arc-shaped plate that fits against the outer wall of the inner cavity 18, as well as a conductive strip on the outside of the arc-shaped plate. The conductive strip and the arc-shaped plate are integrally formed to form the heat transfer plate 4.
[0025] The heat transfer plate 4 includes one or two of the following: quicklime, magnesium powder, iron powder, salt, and bentonite or diatomaceous earth.
[0026] The heating jacket 2 has a honeycomb-shaped heat insulation jacket on the outside and a heat insulation layer on the inside.
[0027] The bottle label part 6 includes an insulation part 61, an inner heat-gathering sleeve 62, an inner metal plate 64, a uniformly distributed perforated chamber 65 on the inner metal plate 64, and paraffin wax 66 filling the perforated chamber 65. An insertion port 63 is provided at the heat-gathering sleeve 62, and the insertion part 41 is inserted into the insertion port 63.
[0028] In essence, the pore 65 and the paraffin 66 inside the pore 65 are set in the form of microcapsules, which occupy little space, are lightweight after solidification, and facilitate the concentration of heat in various parts of the bottle, and the heating is uniform.
[0029] The heating jacket 2 is equipped with a hook rope 7, which is hung on the reverse hook 42. When used outdoors, simply hang the hook rope 7 on the reverse hook 42.
[0030] The neck restraint part 3 comes in two lengths, mainly made of soft silicone or elastic textile material, and is used to wrap around the neck of the mannitol bottle. Its main function is to allow the neck restraint part 3 to be opened manually, so that the mannitol bottle can be replaced quickly. Regarding heating sleeve 2, the honeycomb insulation sleeve is used to block internal heat while allowing the conducted heat to quickly dissipate on the surface. During the process of medical staff holding it, the heat they feel is below a safe temperature. Furthermore, during the process of holding it, medical staff may wear protective gloves, which have low friction. The honeycomb structure of the honeycomb insulation sleeve increases the safety during the process of holding it. As for the insulation layer, it can be a common insulation material, such as foam cotton.
[0031] Regarding the bottle label part 6, the bottle label part 6 is suspended on the reverse hook 42 by the hook rope 7. During use, the heat source chamber 1 and the heating sleeve 2 remain separate, meaning that they can be replaced individually or the heating sleeve 2 can be used alone. In this case, it can be suspended on the water rack by the hook rope 7. The specific usage is as follows: Scenario 1: When used in a hospital, given the hospital's well-equipped infrastructure, the heating jacket 2 can be placed directly on the heating device for ten minutes to ensure the temperature remains at 60 degrees Celsius. In this way, the internal built-in metal plate 64 acquires the temperature, causing the internal metal plate 64 in the internal chamber 65 to melt into a transparent liquid. Passive temperature control is achieved through the fixed phase transition point of paraffin, such as 42°C. It is important to note that a low-melting-point wax sheet with a melting point of 45°C is added between the paraffin layer and the outer layer. When the temperature is too high, the wax sheet melts and absorbs heat to prevent the liquid from overheating. Then, the mannitol bottle is placed inside.
[0032] Scenario 2: In emergency situations, by configuring the heat source chamber 1, mannitol can be placed in the label portion 6 first. Then, the hook rope 7 is hung on the reverse hook 42. After that, the reaction filler 14 is placed on the heat-bearing plate 17 in the inner chamber 18. It should be noted that the center of the reaction filler 14 has a hole for the needle head 15 to pass through. After placing the reaction filler 14, the pressure plate 16 is used to press it down. Then, the pressure plate 16 is rotated to fix it on the needle head 15. Then, the water bag 12 is attached to the inside of the fixing cover 11 and fixed to the protective cover 13. When in use, the fixing cover 11 can be pressed to puncture the water bag 12, allowing water to enter the surface of the reaction filler 14 through the hole in the pressure plate 16. It should be noted that the pressure plate 16 has sieve holes, so that when quicklime, magnesium powder, iron powder, and salt come into contact with water... ; ; It should be noted that calcium oxide is the main heat-generating substance, iron powder enhances the exothermic reaction, carbon powder is sometimes used to stabilize the temperature, salt promotes the electrolytic reaction and improves the exothermic efficiency, and bentonite or diatomaceous earth is used as a filler to prevent the reaction from being too fast.
[0033] In addition, the fixed cap 11 is provided with an external vent to release internal pressure and gas. The gas is collected by the built-in cotton wadding. After heat is generated, it is transferred to the bottle label part 6 through the heat transfer plate 4. It should be noted that there are multiple bottle labels 6, which are evenly distributed at the position of the built-in metal plate 64. The heat transfer plate 4 is preferably made of copper sheet, which has a fast heat conduction speed. This can quickly transfer heat to the position of the built-in metal plate 64. Since the heat generated by the above scheme can reach a high temperature, some heat loss is ensured, so that the temperature at the bottle body is about 50 degrees Celsius, which melts the paraffin. After maintaining a temperature of about 45 degrees Celsius, the temperature entering the human body is about 26 degrees Celsius after adding heat loss and heat loss during infusion. The heat source chamber 1 is isolated from the bottle body by the heat insulation plate 5. The heat insulation plate 5 is provided with a vacuum chamber to avoid excessive heat transfer.
[0034] Paraffin-based phase change materials (PCMs) absorb / release latent heat during solid-liquid phase transitions. By precisely selecting the carbon chain length of the paraffin (which determines the phase transition temperature), constant temperature control can be achieved within a target temperature range (e.g., 37-45℃).
[0035] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.
Claims
1. A protective bottle sleeve to prevent mannitol crystallization in winter, characterized in that, include: The heat source chamber (1), heating sleeve (2) and bottle label part (6) are provided. The heat source chamber (1) includes a protective sleeve (13) for placing the reaction packing (14) and a fixed cover (11) detachably connected to the protective sleeve (13). A water bag (12) is attached to the cavity of the fixed cover (11). A needle head (15) is provided on the axis of the protective sleeve (13) and slides on the needle head (15) by a pressure plate (16), so that the tip of the needle head (15) is exposed. The bottle insulation sleeve is detachably connected to the heat source chamber (1), and the inner diameter of the bottle insulation sleeve is adapted to the size of the mannitol bottle. The bottom of the bottle insulation sleeve is provided with a neck restraint part (3). The heat transfer plate (4) is fixedly connected to the inner cavity of the heat source chamber (1), and the insertion part (41) extends downward from the heat source chamber (1) and forms a bent and outward shape. The bottle insulation sleeve is suspended at the reverse hook (42) provided on the insertion part (41).
2. The protective bottle sleeve for preventing mannitol crystallization in winter according to claim 1, characterized in that, The fixing cover (11) includes an annular fixing part and a central circular part. The annular fixing part and the central circular part are connected by an annular silicone. The water bag (12) is attached to the central circular part. An outer ring insert (111) is fixedly connected to the bottom of the annular fixing part, and an inner insert (112) is fixedly connected to the bottom of the central circular part.
3. A protective bottle sleeve for preventing mannitol crystallization in winter according to claim 1, characterized in that, The protective sleeve (13) is provided with an inner chamber (18) for placing the reaction filler (14). The inner chamber (18) is supported by metal material. The inner wall of the inner chamber (18) is fixedly connected to a heat-bearing plate (17). The bottom inner cavity of the protective sleeve (13) is fixedly connected to an insulation plate (5).
4. A protective bottle sleeve for preventing mannitol crystallization in winter according to claim 1, characterized in that, The protective sleeve (13) also has an isolation cavity at the top. The isolation cavity is vacuum-sealed and a pressure ring (19) is provided inside the isolation cavity. The top of the pressure ring (19) is embedded with multiple embedded beads (110).
5. A protective bottle sleeve for preventing mannitol crystallization in winter according to claim 3, characterized in that, The heat transfer plate (4) is provided with an arc-shaped plate that fits against the outer wall of the inner cavity (18) at one end of the heat source chamber (1), and a conductive strip is provided on the outside of the arc-shaped plate. The conductive strip and the arc-shaped plate are integrally formed to form the heat transfer plate (4).
6. A protective bottle sleeve for preventing mannitol crystallization in winter according to claim 1, characterized in that, The heat transfer plate (4) includes one or two of quicklime, magnesium powder, iron powder, salt, and bentonite or diatomaceous earth.
7. A protective bottle sleeve for preventing mannitol crystallization in winter according to claim 1, characterized in that, The heating jacket (2) is provided with a honeycomb-shaped heat insulation jacket on the outside and a heat insulation layer on the inside.
8. A protective bottle sleeve for preventing mannitol crystallization in winter according to claim 1, characterized in that, The bottle label part (6) includes a heat-insulating part (61), and a heat-retaining sleeve (62) is provided on the inner side of the heat-insulating part (61). An internal metal plate (64) is provided inside the heat-retaining sleeve (62). The internal metal plate (64) is provided with uniformly distributed pores (65). The pores (65) are filled with paraffin wax (66). An insertion port (63) is provided at the heat-retaining sleeve (62). The insertion part (41) is inserted into the insertion port (63).
9. A protective bottle sleeve for preventing mannitol crystallization in winter according to claim 7, characterized in that, The heating sleeve (2) is provided with a hook rope (7), which is hung on the reverse hook (42).