A continuous granulator for sample average weight determination

By designing a continuous granulation device with a multi-compartment box and a continuous feeding mechanism, the problem of measurement difficulties caused by the fluctuation of tablet or capsule granule weight was solved, and efficient and convenient sample weight measurement was achieved.

CN224547492UActive Publication Date: 2026-07-24SHANGHAI SINE WANXIANG PHARMA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SHANGHAI SINE WANXIANG PHARMA
Filing Date
2025-06-30
Publication Date
2026-07-24

AI Technical Summary

Technical Problem

In the existing technology, it is difficult to stably control the particle weight fluctuation of tablets or capsules in the pharmaceutical industry, which makes the particle weight determination of the preparation cumbersome, time-consuming and labor-intensive, and the sampling efficiency low.

Method used

Design a continuous granule ejection device for measuring the average weight of samples. It adopts a multi-compartment box and a continuous feeding mechanism, and realizes the continuous ejection of samples through the lever principle, simplifying the operation process.

Benefits of technology

It improves the efficiency and ease of operation of dosage form particle weight determination, and meets the sampling requirements for continuous determination of the weight of multiple tablets.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a kind of continuous granulating device for sample average weight determination, including multi-bin type box and install on the continuous material pushing mechanism of multi-bin type box, and the continuous material pushing mechanism of multi-bin type box includes storage bin and the discharge bin being set to the bottom of storage bin, the mould plate of the bottom of storage bin is equipped with blanking hole, and the left end of discharge bin is set as discharge port;The one end of continuous material pushing mechanism is located in the right end of discharge bin, and is located in the side position of blanking hole, to be measured sample from blanking hole under the reciprocating push of another end falls from the outlet of discharge bin continuously pushes out.The utility model can continuously push out the sample to be measured from the blanking hole of the bottom of storage bin by continuous material pushing mechanism, can satisfy the sampling demand of continuously determining the weight of multiple (granule);And the continuous granulating device structure design is simple, novel, convenient to use, for sampling determination, can effectively improve operating efficiency.
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Description

Technical Field

[0001] This utility model belongs to the field of pharmaceutical quality testing technology, and relates to a sampling device for sample testing, and more particularly to a continuous granule discharge device for determining the average weight of a sample. Background Technology

[0002] In the pharmaceutical industry, due to the instability of tableting and capsule filling equipment and the characteristics of the drug powder itself, the weight of the drug powder contained in tablets or capsules fluctuates during the production process. For drugs that treat diseases, the amount of drug contained in a unit dose, i.e., the weight of each tablet, must be kept within a narrow range. Therefore, pharmaceutical companies strictly control and measure the weight of the tablets, and detect and reject defective products that do not meet the weight requirements.

[0003] Determining the average weight of multi-tablet (capsule) formulation samples is a frequent QC inspection or production control operation, usually requiring continuous measurement of the weight of multiple tablets (capsules). However, currently, tweezers or direct manual sampling is generally used to take samples one by one, which is cumbersome, time-consuming, labor-intensive, and has relatively low sampling efficiency. Utility Model Content

[0004] The technical problem to be solved by this utility model is to provide a continuous particle discharge device for determining the average weight of samples that is simple in structure, novel in design, and efficient and quick in operation, in order to address the shortcomings of the existing technology.

[0005] To solve the above-mentioned technical problems, this utility model adopts the following technical solution:

[0006] A continuous granulation device for determining the average weight of a sample includes a multi-compartment housing and a continuous feeding mechanism mounted on the multi-compartment housing, wherein:

[0007] The multi-compartment box includes a storage compartment and a discharge compartment located at the bottom of the storage compartment. A discharge hole is provided on the mold plate at the bottom of the storage compartment, and the left end of the discharge compartment is provided as a discharge port.

[0008] One end of the continuous feeding mechanism is located at the right end of the discharge bin and on one side of the discharge hole, so that the test sample falling from the discharge hole is continuously pushed out from the outlet of the discharge bin by the reciprocating push of the other end.

[0009] Preferably, the multi-compartment box is divided into a storage compartment, a power pressing compartment, a power reversing compartment, and a discharge compartment by partitions, wherein:

[0010] The power pressing chamber, power reversing chamber, and discharge chamber are respectively located at the top, back, and bottom of the storage chamber, and are connected in a C-shape.

[0011] Preferably, the storage bin and the discharge bin at its bottom are separated by the mold plate, and the discharge hole at the right end of the mold plate is an opening that is larger at the top and smaller at the bottom.

[0012] Preferably, the storage bin has a guide plate at the bottom inner side and an openable cover on the right side.

[0013] Preferably, the right end of the power pressing chamber is provided with a pressing opening that communicates with the outside, and its left end is connected to the top of the power reversing chamber.

[0014] Preferably, the continuous feeding mechanism includes a first link, a second link, and a third link, wherein:

[0015] The first link, the second link, and the third link are respectively located in the power pressing chamber, the power reversing chamber, and the discharge chamber, and are hinged to each other to form a three-bar linkage mechanism with the beginning and end linked.

[0016] Preferably, a button is provided at the right end of the first connecting rod, and a return spring is sleeved on it; one end of the return spring abuts against the button, and the other end abuts against the housing inside the left end of the power pressing chamber.

[0017] Preferably, the button has a square or cylindrical structure and is movably embedded in the pressing opening at the right end of the power pressing chamber.

[0018] More preferably, the upper and lower ends of the second link are hinged to the left ends of the first link and the third link respectively via a first pin and a second pin;

[0019] A fixed shaft is hinged to the middle of the second connecting rod, and the two ends of the fixed shaft are respectively fixedly installed on the two side plates of the multi-compartment box.

[0020] Preferably, the right end of the third link is configured as a push rod, and the right end of the push rod is provided with a first push head and a second push head arranged vertically at intervals.

[0021] The present invention adopts the above technical solution and has the following technical effects compared with the prior art:

[0022] The continuous pelleting device for measuring the average weight of samples provided by this utility model divides a multi-compartment box into a storage compartment and a C-shaped transmission cavity. The sample to be tested can be placed in the storage compartment, and a continuous pushing mechanism is installed in the C-shaped transmission cavity. It is used to continuously push the sample to be tested out of the discharge hole at the bottom of the storage compartment through the lever principle, which can meet the sampling requirements for continuous measurement of the weight of multiple pieces (granules). Moreover, the continuous pelleting device has a simple and novel structural design, is easy and convenient to use, and can effectively improve the operating efficiency when used for sampling and measurement. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the structure of a continuous granulation device for determining the average weight of a sample according to the present invention.

[0024] Figure 2 This is a partially enlarged structural diagram of part A in a continuous granulation device for determining the average weight of a sample according to this utility model. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0026] Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0027] In some embodiments, such as Figure 1 and Figure 2 As shown, a continuous granulation device for determining the average weight of a sample is provided. This device mainly comprises two parts: a multi-compartment housing 100 and a continuous feeding mechanism 200. The continuous feeding mechanism 200, serving as the granulation structure, is installed within the multi-compartment housing 100 and is used to continuously extract the sample 300 to be tested. The sample 300 can be different pharmaceutical preparations, such as pills, tablets, or capsules.

[0028] Specifically, to facilitate sample storage and the installation of the continuous feeding mechanism 200, the multi-compartment housing 100 mainly includes a storage compartment 110 and a discharge compartment 140, with the discharge compartment 140 located at the bottom of the storage compartment 110. The storage compartment 110 is used to store a certain number of samples 300 to be tested, and the discharge compartment 140 is used to install the push rod 208 of the continuous feeding mechanism 200.

[0029] To enable the sample 300 to be tested to be transferred to the discharge hopper 140, a mold plate 111 is provided at the bottom of the storage hopper 110, and a discharge hole 112 of a certain size is opened on the mold plate 111. The lower opening of the discharge hole 112 is located at the right end of the discharge hopper 140, and is vertically connected. The left end of the discharge hopper 140 is set as the discharge port to facilitate the output and sampling of the sample 300 to be tested.

[0030] The output of the test sample 300 is driven by the continuous pushing mechanism 200. The right end of the continuous pushing mechanism 200 is located at the right end of the discharge chamber 140 and on the left side below the discharge hole 112. Driving the continuous pushing mechanism 200 can simultaneously drive the push rod 208 at the other end to move back and forth in the discharge chamber 140. The push rod 208, driven by the reciprocating push, will push the test samples 300 that fall continuously from the discharge hole 112 out of the outlet of the discharge chamber 140 one by one, thereby achieving the purpose of continuous sampling.

[0031] In some of these embodiments, such as Figure 1 As shown, the multi-compartment box 100 is divided into a storage compartment 110, a power pressing compartment 120, a power reversing compartment 130, and a discharge compartment 140 by a partition. The power pressing compartment 120, the power reversing compartment 130, and the discharge compartment 140 are respectively located at the top, back, and bottom of the storage compartment 110 and are connected in a C-shape to form a C-shaped transmission cavity for installing the continuous pushing mechanism 200.

[0032] The storage bin 110 and the discharge bin 140 at its bottom are separated by a mold plate 111, and the discharge hole 112 at the right end of the mold plate 111 is an opening that is larger at the top and smaller at the bottom. Mold plates 111 with different numbers or diameters of discharge holes 112 can be selected as needed to meet the measurement requirements of different sizes or different sampling quantities.

[0033] To avoid the accumulation of test samples 300 in the storage bin 110 and the problem of large sampling margin, a guide plate 113 is provided on the inner bottom of the storage bin 110. The top of the guide plate 113 is designed with an arc shape to diffuse the test samples 300 accumulated in the storage bin 110 into the lower discharge hole 112, thereby improving the utilization rate and sampling efficiency of the test samples 300 in the storage bin 110.

[0034] An openable cover 114 is provided on the right side wall of the storage hopper 110. The cover 114 can be designed as a sliding door or a hinged door, used to replenish the sample 300 to be tested into the storage hopper 110. A transparent observation window can be installed on the cover 114 as needed to observe the remaining sample level and feeding status within the storage hopper 110.

[0035] In addition, a pressing opening communicating with the outside is provided at the right end of the power pressing chamber 120 to facilitate the installation of button 201, and its left end is connected to the top of the power reversing chamber 130 for the installation of the first link 202 and the second link 203.

[0036] In some of these embodiments, such as Figure 1As shown, the continuous feeding mechanism 200 includes a first link 202, a second link 203, and a third link 207, wherein the first link 202, the second link 203, and the third link 207 are respectively disposed in the power pressing chamber 120, the power reversing chamber 130, and the discharge chamber 140, and are hinged to each other to form a three-bar linkage mechanism with the beginning and end linked. As needed, the continuous feeding mechanism 200 can be driven manually or electrically.

[0037] As a preferred implementation, such as Figure 1 and Figure 2 As shown, a button 201 is fixedly installed at the right end of the first connecting rod 202. The button 201 can be moved left and right and is installed in the pressing opening at the right end of the power pressing chamber 120 for easy manual operation. When the button 201 is pressed to the leftmost position, the three-bar linkage consisting of the first connecting rod 202, the second connecting rod 203, and the third connecting rod 207 can synchronously drive the third connecting rod 207 to reciprocate. The direction of its movement is opposite to that of the button 201, thereby pushing the sample 300 to be tested, which falls continuously from the feeding hole 112, out of the outlet of the discharge chamber 140 to achieve the sampling purpose.

[0038] To reset the continuous feeding mechanism 200, a reset spring 211 is fitted onto the first connecting rod 202. One end of the reset spring 211 abuts against the button 201, and the other end abuts against the housing inside the left end of the power pressing chamber 120. When the button 201 is pressed, the reset spring 211 is compressed. When the pressing force on the button 201 is released, the reset spring 211 resets and pushes the button 201 to the right, simultaneously driving the first connecting rod 202, the second connecting rod 203, and the third connecting rod 207 to move, which in turn drives the push rod 208 at the end of the third connecting rod 207 to reset to the left.

[0039] To improve the structural stability of the button 201 during use and prevent it from wobbling at the opening of the power pressing chamber 120, the button 201 is designed as a square or cylindrical structure according to the inner shape of the power pressing chamber 120, and is movably embedded in the pressing opening at the right end of the power pressing chamber 120.

[0040] like Figure 1 As shown, the upper and lower ends of the second connecting rod 202 are hinged to the left ends of the first connecting rod 202 and the third connecting rod 207 via the first pin 204 and the second pin 206, respectively. A fixed shaft 205 is hinged to the middle of the second connecting rod 202, and the two ends of the fixed shaft 205 are fixedly installed on the two side plates of the multi-compartment box 100, respectively.

[0041] like Figure 2As shown, in order to enable the continuous feeding mechanism 200 to push the sample 300 to be tested out of the feeding hole 112 stably and accurately, the right end of the third connecting rod 207 is set as a push rod 208 with a specific structural design. The right end of the push rod 208 is provided with a first push head 209 and a second push head 210 arranged at intervals and both having a pointed conical structure.

[0042] Specifically, the first pusher 209 is located at the lower end, and the second pusher 210 is located at the upper end, with the length of the first pusher 209 being greater than the length of the second pusher 210, so as to stably push the sample 300 to be tested out from the feed hole 112. The third connecting rod 207, the pusher 208, and the first pusher 209 and the second pusher 210 at their right ends are designed as an integral structure.

[0043] The continuous pelleting device for measuring the average weight of the sample divides the multi-compartment box 100 into a storage compartment 110 and a C-shaped transmission cavity consisting of a power pressing compartment 120, a power reversing compartment 130, and a discharge compartment 140. The sample to be tested can be placed in the storage compartment 110. The continuous pushing mechanism 200 is installed in the C-shaped transmission cavity and is used to continuously push the sample to be tested out from the discharge hole 112 at the bottom of the storage compartment through the lever principle, so as to meet the sampling requirements for continuous measurement of the weight of multiple pieces (granules).

[0044] Finally, the following points should be noted: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installation", "connection", and "linkage" should be interpreted broadly, and can be mechanical or electrical connections, or internal connections between two components, or direct connections. "Up", "down", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may change.

[0045] Secondly, the accompanying drawings of the embodiments disclosed in this utility model only involve the structures involved in the embodiments disclosed in this utility model. Other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of this utility model can be combined with each other.

[0046] Finally, the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A continuous granulation device for determining the average weight of a sample, characterized in that, It includes a multi-compartment housing and a continuous feeding mechanism mounted on the multi-compartment housing, wherein: The multi-compartment box includes a storage compartment and a discharge compartment located at the bottom of the storage compartment. A discharge hole is provided on the mold plate at the bottom of the storage compartment, and the left end of the discharge compartment is provided as a discharge port. One end of the continuous feeding mechanism is located at the right end of the discharge bin and on one side of the discharge hole, so that the test sample falling from the discharge hole is continuously pushed out from the outlet of the discharge bin by the reciprocating push of the other end.

2. The continuous granulation device for determining the average weight of samples according to claim 1, characterized in that, The multi-compartment box is divided into a storage compartment, a power pressing compartment, a power reversing compartment, and a discharge compartment by partitions, wherein: The power pressing chamber, power reversing chamber, and discharge chamber are respectively located at the top, back, and bottom of the storage chamber, and are connected in a C-shape.

3. The continuous granulation device for determining the average weight of samples according to claim 2, characterized in that, The storage bin and the discharge bin at its bottom are separated by the mold plate, and the discharge hole at the right end of the mold plate is an opening that is larger at the top and smaller at the bottom.

4. The continuous granulation apparatus for determining the average weight of samples according to claim 2, characterized in that, The storage silo has a guide plate at the bottom inside and an openable cover on the right side.

5. The continuous granulation apparatus for determining the average weight of samples according to claim 2, characterized in that, The right end of the power pressing chamber is provided with a pressing opening that communicates with the outside, and its left end is connected to the top of the power reversing chamber.

6. The continuous granulation apparatus for determining the average weight of samples according to claim 1, characterized in that, The continuous feeding mechanism includes a first link, a second link, and a third link, wherein: The first link, the second link, and the third link are respectively located in the power pressing chamber, the power reversing chamber, and the discharge chamber, and are hinged to each other to form a three-bar linkage mechanism with the beginning and end linked.

7. The continuous granulation apparatus for determining the average weight of samples according to claim 6, characterized in that, A button is provided at the right end of the first connecting rod, and a return spring is sleeved on it; one end of the return spring abuts against the button, and the other end abuts against the housing inside the left end of the power pressing chamber.

8. The continuous granulation apparatus for determining the average weight of samples according to claim 7, characterized in that, The button has a square or cylindrical structure and is movably embedded in the pressing opening at the right end of the power pressing chamber.

9. The continuous granulation apparatus for determining the average weight of samples according to claim 6, characterized in that, The upper and lower ends of the second link are respectively hinged to the left ends of the first link and the third link via the first pin and the second pin. A fixed shaft is hinged to the middle of the second connecting rod, and the two ends of the fixed shaft are respectively fixedly installed on the two side plates of the multi-compartment box.

10. The continuous granulation apparatus for determining the average weight of samples according to claim 6, characterized in that, The right end of the third link is configured as a push rod, and the right end of the push rod is provided with a first push head and a second push head arranged at intervals.