Microbial sample automatic smear machine

Abstract

The utility model provides a kind of microbial sample automatic smear machine, belong to microorganism processing technical field.It solves the single type of existing microbial sample automatic smear machine glass slide, the partial less of loading, and the problem of sterilization after smearing.It includes the rack with flat plate, sample transmission channel being located on flat plate, oscillation module, sample uncovering module and sample delivery module, flat plate is also equipped with slide placing module, smearing site, slide transfer module and slide smearing module, slide transfer module is used to transfer glass slide between slide placing module and smearing site, slide smearing module is used to dip sample and smears sample on the glass slide in smearing site, slide placing module includes the drying groove of glass slide, printing device, slide placing box and slide collection rack, and vertical placement groove is equipped on collection rack.Vertical placement groove on slide collection rack can limit glass slide, improve the stability of glass slide;Printed device is set, and the marking of glass slide is realized.

Description

Technical Field

[0001] This utility model belongs to the field of microbial processing technology and relates to an automatic microbial sample smear machine. Background Technology

[0002] This applicant has applied for an automated microbial sample smear device [authorization announcement number CN222784378U], comprising a frame with a flat plate on it. The flat plate has a sample cup transport channel, a shaking position, a cap opening positioning sleeve, a smear pen holder, an infrared sterilizer, a slide placement box, a slide collection rack, and a smear position. The frame has a sample processing module for transferring sample cups, a cap opening module for opening and closing the cap, and a slide processing module for transferring slides. The smear pen holder holds an inoculation needle and a smear pen that can be transferred by the sample processing module. The smear pen has an adaptive smear head that is adapted to the upper surface of the slide located in the smear position. However, the stability is poor because the slides are inserted laterally into the slide collection rack; there is no sterilization device for the slides after smearing, which fails to meet biosafety requirements; and the types of slides are limited and the quantity is insufficient. Utility Model Content

[0003] The purpose of this invention is to address the aforementioned problems in existing technologies by proposing an automated microbial sample preparation machine that can stably place glass slides.

[0004] The objective of this utility model can be achieved through the following technical solutions:

[0005] An automated microbial sample smear machine includes a frame with a flat plate, a sample transfer channel on the flat plate, a shaking module, a sample capping module, and a sample transfer module. The sample cup transfer module is used to transfer sample cups between the sample transfer channel, the shaking module, and the sample capping module. The flat plate also includes a slide placement module, a smear position, a slide transfer module, and a slide smear module. The slide transfer module is used to transfer slides between the slide placement module and the smear position. The slide smear module is used to pick up samples and smear them onto the slides in the smear position. The slide placement module includes a slide drying tank, a printing device, a slide placement box, and a slide collection rack. The slide collection rack has a vertical placement groove.

[0006] The slide collection rack is equipped with a vertical placement slot, which allows the slides to be placed vertically. The vertical placement slot limits the position of the slides and improves their stability.

[0007] In the above-mentioned automated microbial sample smear machine, the frame is provided with an ultraviolet lamp cover located above the plate, and the inner top of the ultraviolet lamp cover is provided with an ultraviolet lamp; the plate is provided with a first linear module, and the first linear module is provided with a collection rack placement plate driven by the first linear module. The glass slide collection rack is placed on the collection rack placement plate, and the first linear module is used to drive the collection rack placement plate to enter / exit the ultraviolet lamp cover.

[0008] Ultraviolet lamps housed within the UV lamp cover can sterilize the slides in the slide collection rack, ensuring the biosafety of the slides. An opening is provided on the side of the UV lamp cover to facilitate the entry and exit of the collection rack placement plate.

[0009] In the aforementioned automated microbial sample smear machine, at least two slide collection racks are arranged side-by-side on the collection rack placement plate. Each slide collection rack has multiple vertical placement slots arranged side-by-side. The top of each slide collection rack has a clearance slot extending perpendicular to the width of the vertical placement slots. The smear area on the slide inserted into the vertical placement slot is directly opposite the clearance slot. The minimum number of slide collection racks (at least two) allows for the placement of different types of slides. The clearance slots prevent contact between the smear area on the slide and the slide collection rack, thus avoiding scratching of the smear area.

[0010] The slide rack placement plate has positioning slots that are equal in number and compatible with the number of slide racks. The bottom of the slide rack is fitted into the positioning slots, which can ensure the positioning accuracy and stability of the slide rack and facilitate the accurate placement of slides into the slide rack.

[0011] In the aforementioned automated microbial sample smear machine, the plate is equipped with a drying station, and multiple drying chambers for placing glass slides are arranged side-by-side at the drying station. A partition is installed between two adjacent drying chambers, and each drying chamber has an adsorption port at its bottom connected to a negative pressure system. The drying station is a drying chamber containing heating elements to dry the glass slides placed in the drying chambers. The negative pressure system is located below the plate and connected to the adsorption port via pipes to adsorb aerosols and other impurities. The partitions separate adjacent drying chambers, preventing cross-contamination of the glass slides.

[0012] In the above-mentioned automatic microbial sample smear machine, a support plate is provided below the drying tank. The support plate has multiple mounting slots that are equal in number to the number of slide placement boxes and are arranged in a one-to-one correspondence. A positioning protrusion is provided in the middle of the mounting slot. The slide placement box is located in the mounting slot and has a relief cavity at the bottom that is adapted to the positioning protrusion.

[0013] The slide holder, positioned within the mounting groove, is located using positioning protrusions and clearance cavities, ensuring its positional accuracy. A proximity switch for sensing the slide holder's position is provided on the support plate. Specifically, a through hole opposite the slide holder is provided on the support plate, and the proximity switch is located at the bottom of the through hole. The distance between the proximity switch and the slide holder determines whether it is properly positioned.

[0014] In the aforementioned automated microbial sample smear machine, the slide transfer module includes an X-axis linear module mounted above a flat plate, a Y-axis linear module driven by the X-axis linear module mounted on the X-axis linear module, and a Z-axis linear module driven by the Y-axis linear module mounted on the Y-axis linear module. The Z-axis linear module is equipped with a mounting plate driven by the Z-axis linear module. A rotary motor is mounted on the mounting plate, and a suction cup connecting block is mounted on the rotating shaft of the rotary motor. A suction cup is mounted on the suction cup connecting block.

[0015] The suction cup is connected to a negative pressure source via a pipe, and the generated negative pressure adsorbs the glass slide. A rotary motor drives the suction cup connecting block to rotate back and forth within a 90° range, moving the suction cup connecting block from a vertical position to a horizontal position. The adsorbed glass slide then moves from a horizontal position to a vertical position, making it easy to place the glass slide into the vertical placement slot.

[0016] To position the glass slide, a U-shaped groove is provided at the end of the suction cup connecting block away from the rotating motor shaft. The suction cup is placed in the U-shaped groove, and the glass slide is positioned by the ends of the two side walls of the U-shaped groove.

[0017] In the aforementioned automated microbial sample smear machine, the printing device is a laser printer mounted on a mounting plate. The laser printer can print barcode information onto a glass slide located in the drying tank.

[0018] In the aforementioned automated microbial sample smear machine, a support column is provided on the plate, and a camera module is mounted on the support column, with the camera module facing the smear position. The camera module can capture the smearing process of the glass slide.

[0019] In the aforementioned automated microbial sample smear machine, the plate is equipped with a sample collection rack located above the sample transfer channel, and the sample transfer module is also used to transfer unqualified sample cups and smeared sample cups to the sample collection rack.

[0020] Compared with existing technologies, this automated microbial sample smear machine has the following advantages:

[0021] The vertical placement slots on the slide collection rack limit the position of the slides, improving their stability; the ultraviolet lamp sterilizes the slides, ensuring biosafety; there are at least two slide collection racks to accommodate different types of slides; multiple drying tanks allow for simultaneous drying of different types of slides, improving efficiency; partitions prevent cross-contamination; a camera module records the smearing process; and a laser printer prints barcode information onto the slides for quick identification. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of an automated microbial sample smear machine.

[0023] Figure 2 This is a top view of part of the structure of an automated microbial sample smear machine.

[0024] Figure 3 This is a partial structural diagram of an automated microbial sample smear machine.

[0025] Figure 4 This is a schematic diagram of another part of the structure of an automated microbial sample smear machine.

[0026] Figure 5 This is a schematic diagram of the structure of the slide placement module, the smearing position, and the slide transfer module.

[0027] Figure 6 This is a schematic diagram of the glass slide placement module and the coating position.

[0028] In the diagram: 1. Flat plate; 2. Frame; 3. Sample transfer channel; 4. Shaking module; 5. Sample cap opening module; 6. Sample transfer module; 7. Sample cup; 8. Smear position; 9. Slide smear module; 10. Slide placement box; 11. Slide collection rack; 12. Vertical placement slot; 13. UV lamp cover; 14. First linear module; 15. Collection rack placement plate; 16. Clearance slot; 17. Drying tank; 18. Partition; 19. 20. Adsorption port; 21. Support plate; 22. X-axis linear module; 23. Y-axis linear module; 24. Z-axis linear module; 25. Mounting plate; 26. Rotary motor; 27. Suction cup connecting block; 28. Suction cup; 29. ​​Laser printer; 30. Support column; 31. Camera module; 32. Sample collection rack; 33. Scanning head; 34. Infrared sterilizer; 35. Smear pen holder; 36. Opening positioning sleeve; 37. Second linear module. Detailed Implementation

[0029] The following are specific embodiments of the present invention, which are described in conjunction with the accompanying drawings. However, the present invention is not limited to these embodiments.

[0030] like Figure 1 The automated microbial sample smear machine shown includes a frame 2 with a plate 1 on it. In order to protect the internal structure of the frame 2, a protective shell (not shown in the figure) is provided on the outside of the frame 2.

[0031] like Figure 2 As shown, the plate 1 has two parallel sample transfer channels 3, an oscillation module 4 adjacent to the sample transfer channels 3, a cap-opening positioning sleeve 35, a smear pen holder 34 for placing the smear pen, an infrared sterilizer 33 for sterilizing the smear pen, and a smear position 8. A second linear module 36 is provided on the plate 1, and the cap-opening positioning sleeve 35 is mounted on and driven by the second linear module 36. A scanning head 32 is provided at the end of the sample transfer channels 3, and a sample collection rack 31 is provided above the sample transfer channels 3. Figure 3 As shown, the sample collection rack 31 has a fence on its side, and the fence has an opening structure that makes it easy to hold.

[0032] For convenient transfer of sample cup 7, such as Figure 1 and Figure 3 As shown, a sample transfer module 6 is installed above the plate 1. The structure of this sample transfer module 6 is the same as that in the authorization announcement number CN222784378U. Both modules use a three-axis linear module to drive the adsorption head to adsorb and move the sample cup 7. This sample transfer module 6 moves the sample cup 7 between the sample transfer channel 3, the oscillation module 4, the opening and positioning sleeve 35, and the sample collection rack 31.

[0033] To achieve opening the lid, such as Figure 1 As shown, a sample opening module 5 is set above the second linear module 36 (refer to the structure of the opening module in CN222784378U). The sample transfer module 6 picks up the sample cup 7 on the sample transfer channel 3 and places it into the opening positioning sleeve 35. The second linear module 36 drives the opening positioning sleeve 35 to move to the bottom of the sample opening module 5, and the sample opening module 5 opens the sample cup 7.

[0034] like Figure 1 and Figure 4 As shown, a slide smear module 9 is also provided above the plate 1. The structure of the slide smear module 9 is the same as that in the authorization announcement number CN222784378U. Both use a three-axis linear module to pick up the smear pen to the infrared sterilizer 33 for sterilization, dip it into the sample cup 7 after opening the lid, and smear it onto the slide located at the smear position 8. After the smear is completed, the smear pen is put back into the smear pen holder 34.

[0035] like Figure 1 , Figure 4 and Figure 5As shown, a slide placement module and a slide transfer module are also provided on the plate 1. The slide transfer module is used to transfer the slide between the slide placement module and the smear position 8. Figure 5 As shown, the slide transfer module includes an X-axis linear module 21 mounted above the flat plate 1, a Y-axis linear module 22 driven by the X-axis linear module 21 mounted on the X-axis linear module 21, and a Z-axis linear module 23 driven by the Y-axis linear module 22 mounted on the Y-axis linear module 22. The Z-axis linear module 23 is equipped with a mounting plate 24 driven by the Z-axis linear module 23. A rotary motor 25 is mounted on the mounting plate 24. A suction cup connecting block 26 is mounted on the shaft of the rotary motor 25, and a suction cup 27 is mounted on the suction cup connecting block 26. Figure 5 As shown, the mounting plate 24 is equipped with a laser printer 28, which can print barcode information onto the glass slide located in the drying tank 17.

[0036] Suction cup 27 is connected to a negative pressure source via a pipe, and the generated negative pressure adsorbs and holds the glass slide. For example... Figure 5 As shown, the rotary motor 25 drives the suction cup connecting block 26 to rotate back and forth within a 90° range, causing the suction cup connecting block 26 to move from a vertical state to a horizontal state. The suctioned glass slide then moves from a horizontal state to a vertical state, facilitating the placement of the glass slide into the vertical placement slot 12. To position the glass slide, a U-shaped groove is provided at the end of the suction cup connecting block 26 away from the rotating shaft of the rotary motor 25. The suction cup 27 is placed in this U-shaped groove, and the glass slide is positioned by the ends of the two side walls of the U-shaped groove.

[0037] like Figure 5 and Figure 6 As shown, the slide placement module includes a slide placement box 10 and a slide collection rack 11. The slide collection rack 11 is provided with a vertical placement groove 12, which can be used to place the slides vertically. The vertical placement groove 12 limits the position of the slides and improves the stability of the slides.

[0038] like Figure 5 and Figure 6 As shown, two slide collection racks 11 are arranged side by side on the collection rack placement plate 15. Each slide collection rack 11 has multiple vertical placement slots 12 arranged side by side. The top of the slide collection rack 11 has a clearance slot 16 extending perpendicular to the width direction of the vertical placement slots 12. The smeared area on the slide inserted into the vertical placement slot 12 faces the clearance slot 16. The number of slide collection racks 11 is at least two, which can meet the placement of different types of slides. By setting the clearance slot 16, the smeared area on the slide can be prevented from contacting the slide collection rack 11, thus avoiding scratching of the smeared area.

[0039] The collection rack placement plate 15 has a number of positioning grooves that are equal to and compatible with the number of slide collection racks 11. The bottom of the slide collection rack 11 is fitted into the positioning groove, which can ensure the positioning accuracy and stability of the slide collection rack 11 and facilitate the accurate placement of slides into the slide collection rack 11.

[0040] like Figure 6 As shown, the plate 1 has a drying area with five drying chambers 17 arranged side-by-side for placing glass slides. A partition 18 is provided between two adjacent drying chambers 17. Each drying chamber 17 has an adsorption port 19 at its bottom, connected to a negative pressure system. The negative pressure system is located below the plate 1 and connected to the adsorption port 19 via a pipe. It can adsorb impurities such as aerosols and is connected to a high-efficiency filter located below the plate 1. A heating element is installed below the drying area to dry the glass slides placed in the drying chambers 17.

[0041] like Figure 5 and Figure 6 As shown, a support plate 20 is provided at the drying position. The support plate 20 has two mounting slots that correspond one-to-one with the slide placement box 10. A positioning protrusion is provided in the middle of the mounting slot. The slide placement box 10 is located in the mounting slot and has a relief cavity at the bottom that matches the positioning protrusion. The positioning protrusion and the relief cavity can be used to position the slide placement box 10 in the mounting slot, ensuring the positional accuracy of the slide placement box 10. A proximity switch for sensing the position of the slide placement box 10 is provided on the support plate 20. Specifically, a through hole is provided on the support plate 20 opposite to the slide placement box 10, and the proximity switch is located at the bottom of the through hole. The distance between the proximity switch and the slide placement box 10 can be used to determine whether the slide placement box 10 is in place.

[0042] like Figure 4-6 As shown, a UV lamp cover 13 is mounted on the frame 2 above the flat plate 1, and a UV lamp is installed on the inner top of the UV lamp cover 13. Figure 5 As shown, a first linear module 14 is provided on the flat plate 1, and a collection rack placement plate 15 driven by the first linear module 14 is provided on the first linear module 14. A slide collection rack 11 is placed on the collection rack placement plate 15. The first linear module 14 is used to drive the collection rack placement plate 15 into / out of the ultraviolet lamp cover 13. Ultraviolet lamps located inside the ultraviolet lamp cover 13 can sterilize the slides stored in the slide collection rack 11 using ultraviolet light, thus ensuring the biosafety of the slides. To facilitate the entry and exit of the collection rack placement plate 15, an opening is provided on the side of the ultraviolet lamp cover 13.

[0043] like Figure 5 and Figure 6 As shown, a support column 29 is provided on the flat plate 1, and a camera module 30 is provided on the support column 29. The camera module 30 is directly facing the coating position 8, and the camera module 30 can capture the coating process of the glass slide.

[0044] The smearing method of this automated microbial sample smearing machine includes the following steps:

[0045] Step 1: Place the sample cup 7 into the sample transfer channel 3, and transport the sample cup 7 to the end of the sample transfer channel 3. The sample transfer module 6 uses the suction head to transfer the sample cup 7 at the end of the sample transfer channel 3 to the scanning head 32, and scans the barcode information on the sample cup 7. Sample cups 7 that meet the requirements proceed to the next step, while sample cups 7 that do not meet the requirements are transferred to the sample collection rack 31 to wait for centralized processing.

[0046] Step 2: The sample transfer module 6 uses the adsorption head to transfer the sample cup 7 that meets the requirements scanned by the scanning head 32 to the opening positioning sleeve 35, and then the second linear module 36 transmits the opening positioning sleeve 35 to the area directly below the sample opening module 5.

[0047] Step 3: The sample opening module 5 picks up the lid of the sample cup 7 through the suction cup and rotates it to separate the lid from the sample cup 7. Under the action of the second linear module 36, the opened sample cup 7 is sent to the movement range of the slide smear module 9.

[0048] Step 4: The slide smear module 9 picks up the smear pen on the smear pen holder 34, dips it into the biological sample in the sample cup 7, and transfers it to the slide that has been pre-moved from the slide placement box 10 to the smear position 8 by the slide transfer module.

[0049] Step 5: The second linear module 36 returns the opening positioning sleeve 35 to the area directly below the sample opening module 5, and the sample opening module 5 puts the cup lid back on the sample cup 7; the sample transfer module 6 moves the smear pen into the infrared sterilizer 33 for sterilization and then puts it back into the smear pen holder 34.

[0050] Step 6: The slide transfer module picks up the slide from the coating position 8 and places it into the drying tank 17, where it is dried. The laser printer 28, located on the slide transfer module, prints barcode and other information onto the slide.

[0051] Step 7: The slide transfer module transfers the slides located in the slide placement box 10 to the smear position 8, and then absorbs the dried slides and rotates them 90° before inserting them into the vertical placement slot 12 of the slide collection rack 11.

[0052] Step 8: When the slide collection rack 11 is full of slides, the first linear module 14 drives the slide collection rack 11 into the ultraviolet lamp cover 13, and sterilizes the slides by the ultraviolet lamp located on the top of the ultraviolet lamp cover 13. Then the slide collection rack 11 is taken out from the ultraviolet lamp cover 13.

[0053] The structures / modules not described above are the same as those in the patent announcement number CN222784378U. Since they are not the inventive points of this application, detailed descriptions are omitted.

[0054] The specific embodiments described herein are merely illustrative examples illustrating the spirit of this utility model. Those skilled in the art to which this utility model pertains may make various modifications or additions to the described specific embodiments or use similar methods to substitute them, without departing from the spirit of this utility model or exceeding the scope defined by the appended claims.

Claims

1. An automated microbial sample smear machine, comprising a frame (2) having a flat plate (1), a sample transfer channel (3) disposed on the flat plate (1), a shaking module (4), a sample capping module (5), and a sample transfer module (6), wherein the sample transfer module (6) is used to transfer sample cups (7) between the sample transfer channel (3), the shaking module (4), and the sample capping module (5), wherein the flat plate (1) is further provided with a slide placement module, a smear position (8), a slide transfer module, and a slide smear module (9), wherein the slide transfer module is used to transfer glass slides between the slide placement module and the smear position (8), and the slide smear module (9) is used to pick up samples and smear the samples onto the glass slide located at the smear position (8), characterized in that, The slide placement module includes a slide drying tank (17), a printing device, a slide placement box (10), and a slide collection rack (11), with a vertical placement slot (12) on the slide collection rack (11).

2. The automated microbial sample smear machine according to claim 1, characterized in that, The frame (2) is provided with an ultraviolet lamp cover (13) located above the plate (1), and the top of the ultraviolet lamp cover (13) is provided with an ultraviolet lamp; the plate (1) is provided with a first linear module (14), and the first linear module (14) is provided with a collection rack placement plate (15) driven by the first linear module (14). The glass slide collection rack (11) is placed on the collection rack placement plate (15), and the first linear module (14) is used to drive the collection rack placement plate (15) to enter / exit the ultraviolet lamp cover (13).

3. The automated microbial sample smear machine according to claim 2, characterized in that, At least two slide collection racks (11) are arranged side by side on the collection rack placement plate (15). Each slide collection rack (11) has multiple vertical placement slots (12) arranged side by side. The top of the slide collection rack (11) has a clearance slot (16) extending in a direction perpendicular to the width of the vertical placement slot (12). The smear area on the slide inserted in the vertical placement slot (12) is directly opposite the clearance slot (16).

4. The automated microbial sample smear machine according to claim 1, characterized in that, The plate (1) is provided with a drying position, and multiple drying tanks (17) are arranged side by side at the drying position. A partition (18) is provided between two adjacent drying tanks (17). The bottom of each drying tank (17) is provided with an adsorption port (19) connected to the negative pressure system.

5. The automated microbial sample smear machine according to claim 4, characterized in that, Below the drying tank (17) is a support plate (20). The support plate (20) has multiple mounting slots that are equal in number to and correspond one-to-one with the number of slide boxes (10). The mounting slots have a positioning protrusion in the middle. The slide boxes (10) are located in the mounting slots and have a relief cavity at the bottom that is adapted to the positioning protrusion.

6. The automated microbial sample smear machine according to claim 1, characterized in that, The slide transfer module includes an X-axis linear module (21) disposed above the flat plate (1), a Y-axis linear module (22) driven by the X-axis linear module (21) disposed on the X-axis linear module (21), and a Z-axis linear module (23) driven by the Y-axis linear module (22) disposed on the Y-axis linear module (22). The Z-axis linear module (23) is provided with a mounting plate (24) driven by the Z-axis linear module (23). The mounting plate (24) has a rotary motor (25). The rotating shaft of the rotary motor (25) is provided with a suction cup connecting block (26). The suction cup connecting block (26) is provided with a suction cup (27).

7. The automated microbial sample smear machine according to claim 6, characterized in that, The printing device is a laser printer (28) mounted on the mounting plate (24).

8. The automated microbial sample smear machine according to claim 1, characterized in that, The flat plate (1) is provided with a support column (29), and the support column (29) is provided with a camera module (30), which is directly opposite the coating position (8).

9. The automated microbial sample smear machine according to claim 1, characterized in that, The plate (1) is provided with a sample collection rack (31) located above the sample transfer channel (3). The sample transfer module (6) is also used to transfer the unqualified sample cup (7) and the smeared sample cup (7) to the sample collection rack (31).

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