A high-quality pharmaceutical granule granulating device

Abstract

The application discloses a high-quality medicine granule granulating device and belongs to the technical field of medicine granulating processing. The device comprises a feeding hopper, which is sequentially and fixedly connected with an upper circular shell, a lower circular shell and a hollow conical discharging cover from top to bottom. A hot air pipe is fixedly sleeved at the center of the hollow conical discharging cover. A granulating cylinder is fixedly installed in the upper circular shell. Two conical material blocking rings one are fixedly arranged in the lower circular shell. The device can adjust the particle size according to requirements. The granulating holes can be switched by rotating the threaded rod, and the cylinder does not need to be replaced, thereby saving time and effort. The spiral conveying, fan-shaped dispersion and arc-shaped extrusion are cooperated, so that the materials are uniformly mixed and well formed. The multi-stage granulating holes are accurately sorted. The hot air and the porous stirring pipe are cooperated to efficiently dry, stabilize the product quality, release the particles through the conical material blocking rings, ensure the smooth falling, facilitate the monitoring through the transparent observation port, and easily disassemble, wash and maintain through the modular design. The device reduces the energy consumption and cost, improves the production efficiency and product quality, and meets the diversified pharmaceutical requirements.

Description

Technical Field

[0001] This application relates to the field of drug granulation technology, and more specifically, to a high-quality drug granulation apparatus. Background Technology

[0002] The existing publicly available technology has not yet been proposed. Regarding the related technologies mentioned above, the inventor believes that the following defects still exist: Therefore, we propose a high-quality drug granulation device. Utility Model Content

[0003] 1. Technical problems to be solved

[0004] The purpose of this application is to provide a high-quality pharmaceutical granulation device that solves the technical problems mentioned in the background art. This device allows for adjustment of particle size as needed, switching granulation orifices by rotating a threaded rod, eliminating the need for changing cylinders, saving time and labor. The combined use of spiral conveying, fan-shaped dispersion, and arc extrusion ensures uniform material mixing and good forming. Multi-stage granulation orifices provide precise sorting, while hot air and a porous stirring tube facilitate efficient drying, ensuring stable product quality. A conical material-blocking ring slowly releases granules, ensuring smooth descent. A transparent observation port facilitates monitoring, and the modular design allows for easy disassembly, cleaning, and maintenance. This reduces energy consumption and costs, improves production efficiency and product quality, and meets the diverse needs of pharmaceutical manufacturing.

[0005] 2. Technical Solution

[0006] This application provides a high-quality drug granulation device, comprising: a feeding hopper, wherein an upper circular shell, a lower circular shell, and a hollow conical discharge cover are fixedly connected from top to bottom in the feeding hopper, a hot air pipe is fixedly sleeved at the center of the hollow conical discharge cover, a granulation cylinder is fixedly installed inside the upper circular shell, two conical material blocking rings are fixedly provided inside the lower circular shell, and a granulation drive mechanism is installed between the feeding hopper and the lower circular shell;

[0007] The granulation drive mechanism includes a motor, the output end of which is fixedly connected to a spline rod. The spline rod is driven by a spiral conveyor blade, a fan-shaped blade, an arc-shaped extrusion plate, a baffle plate, and a hollow spherical column, which are sequentially connected from top to bottom. The fan-shaped blade, the arc-shaped extrusion plate, and the baffle plate are rotatably disposed inside the granulation cylinder. The hollow spherical column is rotatably disposed inside the lower cylindrical shell. Two conical material blocking rings and multiple horizontal tubes are fixedly sleeved on the outer surface of the hollow spherical column. Multiple porous stirring tubes are fixedly sleeved on the horizontal tubes. The conical material blocking rings are alternately arranged, and two horizontal tubes are arranged between each of the conical material blocking rings. The bottom end of the hollow spherical column is rotatably sleeved with a hot air pipe.

[0008] By adopting the above technical solution, the device adds material into the feed hopper, which extends downwards sequentially to form an upper circular shell, a lower circular shell, and finally a hollow conical discharge hood, creating a complete closed-loop system. A motor drives a splined rod to rotate, causing the spiral conveyor blades, fan-shaped blades, arc-shaped extrusion plate, baffle, and hollow spherical column to rotate. The height of the mounting plate can be precisely adjusted by rotating the threaded rod, thereby changing the position of the baffle within the granulation cylinder and moving the arc-shaped extrusion plate to different granulation hole positions. This achieves the production and processing of drug granules of different sizes. This design solves the problem of frequently changing the granulation cylinder when processing different drug granules, greatly improving the equipment's flexibility and production efficiency. Furthermore, by setting two conical obstruction rings inside the lower circular shell, the falling speed of the granular material can be slowed down. The hot air pipe and horizontal pipe structure enable further stirring, dispersion, and uniform drying of the granular material, stabilizing product quality.

[0009] Optionally, a feed pipe is fixedly connected between the feed hopper and the upper circular shell, the spiral conveyor blade is rotatably disposed inside the feed pipe, and a horizontal plate is rotatably connected to the upper end of the shaft of the spiral conveyor blade, the horizontal plate being fixedly disposed at the upper port of the feed hopper.

[0010] By adopting the above technical solution, the screw conveyor blade is installed inside the feed pipe, which can smoothly transport the loose material in the feed hopper to the granulation cylinder. The shaft of the screw conveyor blade is rotatably connected to the horizontal plate, thus rotating stably and achieving the purpose of continuous material conveying.

[0011] Optionally, the motor is fixedly connected to a mounting plate, and a threaded rod is threadedly mounted on the mounting plate, with the bottom end of the threaded rod rotatably connected to the cross plate.

[0012] By adopting the above technical solution, users can adjust the position of the motor by rotating the threaded rod according to actual needs, thereby changing the particle size processing requirements.

[0013] Optionally, the spline rod is connected to the spiral conveyor blade and the hollow ball column by an insertion fit, and the fan-shaped blade, the arc-shaped extrusion plate and the baffle are fixedly sleeved on the spline rod, and the arc-shaped extrusion plate and the baffle rotate to fit against the inner wall of the granulation cylinder.

[0014] By adopting the above technical solution, the rotational power of the spline rod can simultaneously drive the rotation of the spiral conveyor blade, hollow ball column, fan-shaped blade, arc extrusion plate and baffle. It is made of high-strength materials, and by carefully setting the length ratio of each section, it ensures that each connection point can obtain appropriate torque transmission efficiency.

[0015] Optionally, the upper end of the granulation cylinder has a conical structure, and the upper port is fixedly connected to the feed pipe. The granulation cylinder is provided with multiple rings of granulation holes one, granulation hole two, and granulation hole three from top to bottom.

[0016] By adopting the above technical solution, the upper part of the granulation cylinder is tapered, which helps to guide the material to slide naturally into the working area below. Three small holes of different diameters are regularly arranged on the cylinder body, namely granulation hole one, granulation hole two and granulation hole three. The size of these holes increases sequentially. The position of the arc-shaped extrusion plate can be adjusted according to production needs to achieve different drug particle processing purposes.

[0017] Optionally, the upper circular shell is provided with a transparent observation port.

[0018] By adopting the above technical solution, the existence of the transparent observation port greatly facilitates daily operation and management. The operator can observe the position of the baffle plate, which makes it easy to adjust the position of the arc extrusion plate. Moreover, the operator can intuitively understand the internal operation without frequently opening the machine, and promptly detect abnormalities and take corresponding measures to correct them.

[0019] 3. Beneficial effects

[0020] One or more technical solutions provided in this application have at least the following technical effects or advantages:

[0021] 1. By rotating the threaded rod, the position of the baffle can be easily adjusted, allowing the arc-shaped extrusion plate to move to different granulation holes on the granulation cylinder, enabling the production of multiple specifications of granulated drugs on the same equipment without the need for frequent granulation cylinder replacement, thus greatly saving time and labor costs.

[0022] 2. The combined use of spiral conveyor blades, fan-shaped blades, and arc-shaped extrusion plates ensures continuous and uniform material feeding, and allows for thorough mixing and pre-compression before entering the pelleting cylinder, thus improving the uniformity and density of pellet formation.

[0023] 3. The multi-stage granulation hole design allows users to select the appropriate hole diameter for sorting according to their needs. At the same time, in conjunction with the high-temperature airflow provided by the hot air pipe, the porous stirring tube on the horizontal pipe achieves uniform drying and heating treatment of the granular drugs, effectively removing excess moisture and ensuring stable product quality. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of the overall structure of a high-quality drug granulation apparatus disclosed in a preferred embodiment of this application;

[0025] Figure 2 This is a partial cross-sectional view of a high-quality drug granulation apparatus disclosed in a preferred embodiment of this application;

[0026] Figure 3 A high-quality drug granulation apparatus disclosed in a preferred embodiment of this application Figure 2 Enlarged structural diagram at point A in the middle;

[0027] Figure 4 This is a schematic diagram of the granulation drive mechanism of a high-quality drug granulation device disclosed in a preferred embodiment of this application;

[0028] The following are the labels in the diagram: 1. Feed hopper; 11. Feed pipe; 2. Upper round shell; 21. Transparent observation port; 3. Lower round shell; 31. Conical material blocking ring one; 4. Hollow conical discharge cover; 5. Granulation drive mechanism; 51. Motor; 511. Mounting plate; 512. Threaded rod; 52. Splined rod; 53. Horizontal plate; 54. Spiral conveyor blade; 55. Hollow spherical column; 56. Conical material blocking ring two; 57. Fan-shaped blade; 58. Arc-shaped extrusion plate; 59. Baffle plate; 6. Hot air pipe; 61. Horizontal pipe; 611. Porous stirring pipe; 7. Granulation cylinder; 71. Granulation hole one; 72. Granulation hole two; 73. Granulation hole three. Detailed Implementation

[0029] The present application will be further described in detail below with reference to the accompanying drawings.

[0030] Reference Figures 1 to 4 This application provides a high-quality drug granulation device, comprising: a feeding hopper 1, wherein the feeding hopper 1 is fixedly connected from top to bottom to an upper circular shell 2, a lower circular shell 3 and a hollow conical discharge cover 4, a hot air pipe 6 is fixedly sleeved at the center of the hollow conical discharge cover 4, a granulation cylinder 7 is fixedly installed inside the upper circular shell 2, two conical material blocking rings 31 are fixedly provided inside the lower circular shell 3, and a granulation drive mechanism 5 is installed between the feeding hopper 1 and the lower circular shell 3;

[0031] The granulation drive mechanism 5 includes a motor 51, the output end of which is fixedly connected to a splined rod 52. The splined rod 52 is driven by a spiral conveyor blade 54, a fan-shaped blade 57, an arc-shaped extrusion plate 58, a baffle plate 59, and a hollow spherical column 55, which are sequentially connected from top to bottom. The fan-shaped blade 57, the arc-shaped extrusion plate 58, and the baffle plate 59 are rotatably disposed inside the granulation cylinder 7, and the hollow spherical column 55 is rotatably disposed inside the lower cylindrical shell 3. The outer surface of the hollow spherical column 55 is fixedly sleeved with... There are two conical material-blocking rings 56 and multiple horizontal tubes 61. Multiple porous stirring tubes 611 are fixedly sleeved on the horizontal tubes 61. The conical material-blocking rings 31 and 56 are alternately arranged, and two horizontal tubes 61 are arranged between each of the conical material-blocking rings 31 and 56. The bottom end of the hollow spherical column 55 is rotatably sleeved with the hot air pipe 6. The device is connected by adding material into the feed hopper 1. The feed hopper 1 extends downward in sequence to form an upper circular shell 2, a lower circular shell 3, and finally a hollow structure. The conical discharge hood 4 forms a complete closed-loop system. The spline rod 52 is driven by the motor 51 to rotate, causing the spiral conveyor blade 54, fan-shaped blade 57, arc-shaped extrusion plate 58, baffle 59, and hollow ball column 55 to rotate. The height of the mounting plate 511 can be precisely adjusted by rotating the threaded rod 512, thereby changing the position of the baffle 59 in the granulation cylinder 7 and moving the arc-shaped extrusion plate 58 to different granulation hole positions, thus achieving the purpose of producing and processing drug granules of different sizes. This design solves the problem of frequently changing the granulation cylinder 7 when processing different drug granules, greatly improving the flexibility and production efficiency of the equipment. Furthermore, by setting conical material blocking ring 1 31 and conical material blocking ring 2 56 inside the lower circular shell 3, the falling speed of the granular material can be slowed down. By setting the hot air pipe 6 and the horizontal pipe 61 structure, the purpose of re-stirring and dispersing the granular material and uniformly drying it can be achieved, thus stabilizing product quality.

[0032] Reference Figure 1 and Figure 2 A feed pipe 11 is fixedly connected between the feed hopper 1 and the upper circular shell 2. The spiral conveyor blade 54 is rotatably installed inside the feed pipe 11. A horizontal plate 53 is rotatably connected to the upper end of the shaft of the spiral conveyor blade 54. The horizontal plate 53 is fixedly installed at the upper port of the feed hopper 1. The spiral conveyor blade 54 is installed inside the feed pipe 11, which can smoothly transport the loose material in the feed hopper 1 to the granulation cylinder 7. The shaft of the spiral conveyor blade 54 is rotatably connected to the horizontal plate 53, so that it rotates stably and achieves the purpose of continuous material conveying.

[0033] Reference Figure 1 and Figure 2 The motor 51 is fixedly connected to the mounting plate 511, and a threaded rod 512 is threadedly installed on the mounting plate 511. The bottom end of the threaded rod 512 is rotatably connected to the horizontal plate 53. The user can adjust the position of the motor 51 by rotating the threaded rod 512 according to actual needs, thereby changing the particle size processing production requirements.

[0034] ReferenceFigure 2 and Figure 4 The spline rod 52 is connected to the spiral conveyor blade 54 and the hollow ball column 55 by insertion. The fan-shaped blade 57, the arc-shaped extrusion plate 58 and the baffle 59 are fixedly sleeved on the spline rod 52. The arc-shaped extrusion plate 58 and the baffle 59 rotate and fit against the inner wall of the granulation cylinder 7. The rotational power of the spline rod 52 can simultaneously drive the spiral conveyor blade 54, the hollow ball column 55, the fan-shaped blade 57, the arc-shaped extrusion plate 58 and the baffle 59 to rotate. It is made of high-strength material, and by carefully setting the length ratio of each section, it ensures that each connection point can obtain appropriate torque transmission efficiency.

[0035] Reference Figure 1 and Figure 2 The granulation cylinder 7 has a conical structure at the top and its upper end is fixedly connected to the feed pipe 11. The granulation cylinder 7 is provided with multiple rings of granulation holes 1 71, granulation hole 2 72 and granulation hole 3 73 from top to bottom. The upper part of the granulation cylinder 7 has a conical contraction shape, which is conducive to guiding the material to slide naturally to the working area below. Three small holes of different diameters are regularly arranged on the cylinder body, namely granulation hole 1 71, granulation hole 2 72 and granulation hole 3 73. The size of these holes increases sequentially. The position of the arc extrusion plate 58 can be adjusted according to production needs to achieve different drug particle processing purposes.

[0036] Reference Figure 1 and Figure 2 The upper round shell 2 is provided with a transparent observation port 21. The presence of the transparent observation port 21 greatly facilitates daily operation and management. The operator can observe the position of the baffle 59, which makes it easy to adjust the position of the arc extrusion plate 58. Moreover, the operator can intuitively understand the internal operation without frequently opening the machine, and promptly detect abnormalities and take corresponding measures to correct them.

[0037] Working principle: Based on the required granulation size, rotating the threaded rod 512 causes the mounting plate 511 to drive the motor 51 and splined rod 52 downwards, causing the fan-shaped blades 57, the arc-shaped extrusion plate 58, and the baffle 59 to move along the granulation cylinder 7. The baffle 59 can be observed moving to the granulation hole 71, granulation hole 72, or granulation hole 73 of the granulation cylinder 7 through the transparent observation port 21. This utilizes the different aperture positions of the arc-shaped extrusion plate 58 in the granulation cylinder 7 to achieve the production and processing of different sized drug granules, solving the problem of frequently changing the granulation cylinder 7 when processing different drug granules. When the drug raw material is added to the feed hopper 1 and the motor 51 is started, it drives the splined rod 52 to rotate at high speed, causing the spiral conveyor blades 54 located in the feed pipe 11 to start working, pushing the raw material from the feed hopper 1 along the axial direction into the granulation cylinder 7. The fan-shaped blades 57 further disperse it, and then the arc-shaped extrusion plate 58... The extrusion plate 58 applies pressure to force the drug through the granulation zone of the granulation cylinder 7 with specific apertures, including three granulation apertures: granulation aperture 1 71, granulation aperture 2 72, and granulation aperture 3 73. This cuts the drug into particles of the required size, which fall from the granulation cylinder 7 between the upper shell 2 and the lower shell 3. The falling of the granules is slowed by alternating conical blocking rings 1 31 and 2 56. The hollow spherical column 55 rotates at high speed, causing the horizontal pipe 61, which is equipped with multiple porous stirring tubes 611, to rotate between the conical blocking rings 1 31 and 2 56, further stirring and dispersing the granules. The high-temperature airflow blown in from the hot air pipe 6 enters the hollow spherical column 55 and is conveyed by the porous stirring tubes 611 on the horizontal pipe 61, so that the granules are uniformly dried and heated to help remove excess moisture and produce fresh granules. Finally, the qualified granule drug product is discharged and collected through the hollow structure of the hollow conical discharge cover 4.

Claims

1. A high-quality drug granulation apparatus, characterized in that: Includes: a feeding hopper (1), wherein the feeding hopper (1) is fixedly connected from top to bottom to an upper circular shell (2), a lower circular shell (3) and a hollow conical discharge cover (4), wherein a hot air pipe (6) is fixedly sleeved at the center of the hollow conical discharge cover (4), a granulation cylinder (7) is fixedly installed inside the upper circular shell (2), and two conical material blocking rings (31) are fixedly provided inside the lower circular shell (3), and a granulation drive mechanism (5) is installed between the feeding hopper (1) and the lower circular shell (3); The granulation drive mechanism (5) includes a motor (51), the output end of which is fixedly connected to a spline rod (52). The spline rod (52) is driven by a spiral conveyor blade (54), a fan-shaped blade (57), an arc-shaped extrusion plate (58), a baffle plate (59), and a hollow spherical column (55) connected sequentially from top to bottom. The fan-shaped blade (57), the arc-shaped extrusion plate (58), and the baffle plate (59) are rotatably disposed inside the granulation cylinder (7), and the hollow spherical column (55) rotates... The hollow spherical column (55) is movably installed inside the lower cylindrical shell (3). Two conical material blocking rings (56) and multiple horizontal tubes (61) are fixedly sleeved on the outer surface of the hollow spherical column (55). Multiple porous stirring tubes (611) are fixedly sleeved on the horizontal tubes (61). The conical material blocking rings (31) and (56) are alternately arranged, and two horizontal tubes (61) are arranged between the conical material blocking rings (31) and (56). The bottom end of the hollow spherical column (55) is rotatably sleeved with the hot air pipe (6).

2. The high-quality drug granulation apparatus according to claim 1, characterized in that: A feed pipe (11) is fixedly connected between the feed hopper (1) and the upper round shell (2). The spiral conveyor blade (54) is rotatably disposed inside the feed pipe (11). A horizontal plate (53) is rotatably connected to the upper end of the shaft of the spiral conveyor blade (54). The horizontal plate (53) is fixedly disposed at the upper port of the feed hopper (1).

3. The high-quality drug granulation apparatus according to claim 2, characterized in that: The motor (51) is fixedly connected to a mounting plate (511), and a threaded rod (512) is threadedly installed on the mounting plate (511). The bottom end of the threaded rod (512) is rotatably connected to the horizontal plate (53).

4. The high-quality drug granulation apparatus according to claim 1, characterized in that: The spline rod (52) is connected to the spiral conveyor blade (54) and the hollow ball column (55) by insertion. The fan-shaped blade (57), the arc-shaped extrusion plate (58) and the baffle (59) are fixedly sleeved on the spline rod (52). The arc-shaped extrusion plate (58) and the baffle (59) rotate and fit against the inner wall of the granulation cylinder (7).

5. The high-quality drug granulation apparatus according to claim 2, characterized in that: The upper end of the pelletizing cylinder (7) is a conical structure, and the upper port is fixedly connected to the feed pipe (11). The pelletizing cylinder (7) is provided with multiple rings of pelletizing holes one (71), pelletizing hole two (72) and pelletizing hole three (73) from top to bottom.

6. The high-quality drug granulation apparatus according to claim 5, characterized in that: A transparent observation port (21) is provided on the upper circular shell (2).

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