A mouse holder

CN224735398UActive Publication Date: 2026-09-11CHINA PHARM UNIV
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Patent Information

Application Number
CN202520342334.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-02-28
Publication Date
2026-09-11
Estimated Expiration
2035-02-28

AI Technical Summary

Technical Problem

虽然该小鼠固定器操作简单、效果显著,能够有效避免被小鼠咬伤,使用安全,同时可以进行尾静脉注射、腹腔注射、不同体位照射等实验;但其仍无法实现对动物进行眼眶静脉采血操作

Benefits of technology

本装置可以将小鼠固定于固定器内,避免其挣扎,而且在小鼠眼部有孔洞,便于对小鼠眼部进行操作,如便于对小鼠眼部进行用药、采血等操作,避免了人工保定带来的可能会发生的人员危险,减少小鼠的恐惧及痛苦。

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a mouse holder, specifically relates to the field of animal experiment device, including base, the support plate of setting on the base, be equipped with the fixed cylinder of horizontal setting on the support plate, still include the conical head sleeve of fixed mouse head, the eye hole of being equipped with for mouse eye exposure in the both sides of head sleeve, the nose hole of being equipped with for mouse nose exposure in the one end of head sleeve, the other end of head sleeve is connected with the one end of fixed cylinder, the other end in fixed cylinder is equipped with the baffle, the lower part of baffle is equipped with the tail hole convenient for mouse tail to leak out, the upper part of baffle is equipped with fastening bolt, the upper side of fixed cylinder is equipped with the strip hole convenient for fastening bolt reciprocating sliding, be equipped with the air bag for fixing mouse body in fixed cylinder, the inner side wall of air bag and fixed cylinder forms the interlayer for inflation, the outer side wall of fixed cylinder is equipped with inflation pipe, and is equipped with inflation bag and exhaust valve with inflation pipe is matched. The utility model is convenient for the operation such as orbit venous blood sampling of mouse eye.
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Description

Technical Field

[0001] This utility model belongs to the field of animal experimental devices, specifically relating to a mouse restraint device. Background Technology

[0002] Mouse restraints, also known as immobilizers or behavior restrainers, are generally designed for easy manipulation of the animal's tail. They are typically used for tail vein injection and tail vein blood collection. However, once the restraint is in place, it is impossible to perform orbital vein blood collection on the animal.

[0003] Patent CN208808716U discloses a mouse restraint device, including a cylindrical body and a base for supporting the cylindrical body. One end of the cylindrical body is open, and the other end is constricted. A cap is detachably and fixedly connected to the opening. An axial opening is formed on the cylindrical wall, and an adhesive block for securing the mouse is provided on the inner wall of the cylindrical body. An operating hole is also provided on the cylindrical body. When using the mouse restraint device provided by this invention, the mouse can be placed directly into the cylindrical body through the opening, and the cap can be closed. The operation is quick and saves experimental time. The cap at the opening of the cylindrical body can completely cover the mouse's head, significantly reducing the risk of the operator being bitten. The mouse will also struggle less in the dark. The structure is simple, easy to manufacture, and cost-effective. Although this mouse restraint device is simple to operate, effective, and can effectively prevent mouse bites, and is safe to use, and can be used for experiments such as tail vein injection, intraperitoneal injection, and irradiation in different positions, it still cannot perform orbital vein blood collection on animals.

[0004] To address the above shortcomings, a mouse restraint device is needed to facilitate procedures such as orbital vein blood collection from the mouse's eyes. Utility Model Content

[0005] The purpose of this invention is to provide a mouse restraint device that allows for procedures such as collecting blood from the orbital veins of mice.

[0006] This utility model provides the following technical solution: A mouse restraint device includes a base and a support plate disposed on the base; the support plate is provided with a horizontally disposed fixing cylinder; characterized in that: It also includes a conical head sleeve for fixing the mouse's head, with eye holes on both sides for exposing the mouse's eyes and a nose hole at one end for exposing the mouse's nose; the other end of the head sleeve is connected to one end of the fixing sleeve. The other end of the fixing cylinder is equipped with a baffle, and the lower part of the baffle is equipped with a tail hole to allow the mouse's tail to protrude; the upper part of the baffle is equipped with a fastening bolt, and the upper side of the fixing cylinder is equipped with a strip hole to facilitate the reciprocating sliding of the fastening bolt. The fixing cylinder contains an air bladder for fixing the mouse's body, and an air-filled interlayer is formed between the air bladder and the inner wall of the fixing cylinder for inflation. The outer wall of the fixed cylinder is equipped with an inflation tube, as well as an inflation bladder and an exhaust valve that are matched with the inflation tube.

[0007] Preferably, the fixing cylinder includes an upper fixing cylinder and a lower fixing cylinder, and the upper fixing cylinder and the lower fixing cylinder are provided with connecting ears on both sides, which are connected by adhesive; and the lower fixing cylinder is connected to the support plate. Preferably, the head sleeve includes an upper head sleeve and a lower head sleeve, and the ends of the upper head sleeve and the lower head sleeve are respectively connected to the upper fixed sleeve and the lower fixed sleeve; Preferably, the ends of the upper sleeve and the lower sleeve are integrally formed and connected to the upper fixed cylinder and the lower fixed cylinder, respectively.

[0008] Preferably, the airbag includes a cylindrical rubber surface, with both ends of the rubber surface fitted onto a stiffened flange, and the edge of the stiffened flange tightly connected to the inner side of the fixed cylinder.

[0009] Preferably, the upper and lower fixed cylinders are each provided with a semi-circular sealing groove, and the stiffened flange is embedded in the sealing groove and tightly connected to the inside of the fixed cylinder.

[0010] Preferably, the stiffened flange is provided with an annular limiting groove, and an annular elastic ring is sleeved on the outside of the rubber surface, with the elastic ring embedded in the limiting groove.

[0011] Preferably, there are four elastic rings respectively disposed at both ends of the rubber surface.

[0012] Preferably, all components are made of transparent material.

[0013] The beneficial effects of this utility model are: This device can fix mice in a restraint to prevent them from struggling. It also has holes in the mouse's eyes to facilitate operations such as administering medication or drawing blood. This avoids the potential dangers to personnel associated with manual restraint and reduces the mouse's fear and pain. Attached Figure Description

[0014] The accompanying drawings are provided to further illustrate the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention, but do not constitute a limitation thereof. In the drawings: Figure 1 This is an overall diagram of the device; Figure 2 This is an exploded view of the device.

[0015] The following are marked in the diagram: 1. Base; 2. Support plate; 3. Fixing cylinder; 3a. Upper fixing cylinder; 3b. Lower fixing cylinder; 4. Head sleeve; 4a. Upper head sleeve; 4b. Lower head sleeve; 5. Eye hole; 6. Nose hole; 7. Inflation tube; 8. Exhaust valve; 9. Inflation bladder; 10. Air bladder; 10a. Rubber surface; 10b. Elastic ring; 10c. Neck flange; 11. Sealing groove; 12. Baffle; 13. Tail hole; 14. Connecting ear; 15. Strip hole; 16. Fastening bolt; Detailed Implementation

[0016] Example

[0017] like Figures 1 to 2 A mouse restraint device includes a base 1, which can be made of 304 stainless steel for stability, aesthetics, and reliability; two support plates 2 are mounted on the base 1, and the support plates 2 and the base 1 are integrally formed; a horizontally mounted fixing cylinder 3 is provided on the support plate 2, and the fixing cylinder 3 is made of transparent acrylic; the fixing cylinder 3 and the support plate 2 can be connected by heat fusion; it also includes a conical head sleeve 4 for fixing the mouse's head, the head sleeve 4 is made of transparent acrylic, and has eye holes 6 on both sides for exposing the mouse's eyes, and a nose hole 6 at one end for exposing the mouse's nose; the other end of the head sleeve 4 is connected to one end of the fixing cylinder 3; A baffle 12 is provided inside the other end of the fixing cylinder 3. The lower part of the baffle 12 has a tail hole 13 to allow the mouse's tail to protrude. A fastening bolt 16 is provided on the upper part of the baffle 12. The upper side of the fixing cylinder 3 has a strip hole 15 to facilitate the reciprocating sliding of the fastening bolt 16. By rotating the fastening bolt 16, the baffle 12 is moved to a suitable position. Then, rotating the fastening bolt 16 again limits the distance between the nut of the fastening bolt 16 and the fixing cylinder 3. The specific structure of the fastening bolt 16 can be as shown in the attached figure. Figure 2 The structure; The fixing cylinder 3 contains an air bladder 10 for fixing the mouse's body, and an air-filled interlayer is formed between the air bladder 10 and the inner wall of the fixing cylinder 3 for inflation; the outer wall of the fixing cylinder 3 is provided with an inflation tube 7, as well as an inflation bladder 9 and an exhaust valve 8 that are matched with the inflation tube 7. The inflation bladder 9 and the exhaust valve 8 are both existing publicly available technologies, and their specific principles will not be described in detail. During the experiment, the mouse's body is inserted through the air bladder 10, the mouse's head is placed inside the head sleeve 4, the baffle 12 is placed and moved to a suitable position so that the mouse's tail protrudes from the tail hole 13, the fastening bolt 16 is tightened, and then air is inflated into the interlayer through the air bladder 9 and the air tube 7. The air bladder 10 expands, preventing the mouse from moving or struggling freely. Once the eyeballs protrude, the corresponding eye operation is performed. After the experiment is completed, the air is released through the exhaust valve 8 and the mouse is removed.

[0018] Example

[0019] Based on Example 1, in order to better ensure sealing and facilitate assembly, such as Figure 2 The fixing cylinder 3 includes an upper fixing cylinder 4a and a lower fixing cylinder 4b. The upper fixing cylinder 4a and the lower fixing cylinder 4b are provided with connecting ears 14 on both sides. The connecting ears 14 are connected by adhesive to ensure airtightness. The lower fixing cylinder 4b is connected to the support plate 2 to achieve support and fixation. The head sleeve 4 includes an upper head sleeve 4a and a lower head sleeve 4b. The ends of the upper head sleeve 4a and the lower head sleeve 4b are integrally formed and connected to the upper fixing cylinder 3a and the lower fixing cylinder 3b, respectively. The airbag 10 includes a cylindrical rubber surface 10a, which is made of a head-shaped material. Both ends of the rubber surface 10a are fitted onto a stiffening flange 10c. The stiffening flange 10c is simply a descriptive name; for its specific structure, please refer to the appendix. Figure 2 The upper fixed cylinder 4a and the lower fixed cylinder 4b are respectively provided with semi-arc sealing grooves 11. The stiffened flange 10c is embedded in the sealing groove 11 and tightly connected to the inner side of the fixed cylinder 4, thereby realizing the sandwich structure between the rubber surface 10a and the upper fixed cylinder 4a and the lower fixed cylinder 4b, and can effectively ensure the airtightness. To further improve the sealing performance, the stiffened flange 10c is provided with an annular limiting groove, and the annular elastic ring 10b is sleeved on the outside of the rubber surface 10a, with the elastic ring 10b embedded in the limiting groove; there are 4 elastic rings 10b respectively set at both ends of the rubber surface 10a; in order to facilitate the observation of the experiment, all the components involved are made of transparent material.

[0020] The above are merely preferred embodiments of the present utility model and are not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A mouse restraint device, comprising a base and a support plate disposed on the base; the support plate is provided with a horizontally disposed fixing cylinder; characterized in that: It also includes a conical head sleeve for fixing the mouse's head, with eye holes on both sides for exposing the mouse's eyes and a nose hole at one end for exposing the mouse's nose; the other end of the head sleeve is connected to one end of the fixing sleeve. The other end of the fixing cylinder is equipped with a baffle, and the lower part of the baffle is equipped with a tail hole to allow the mouse's tail to protrude; the upper part of the baffle is equipped with a fastening bolt, and the upper side of the fixing cylinder is equipped with a strip hole to facilitate the reciprocating sliding of the fastening bolt; The fixing cylinder contains an air bladder for fixing the mouse's body, and an air-filled interlayer is formed between the air bladder and the inner wall of the fixing cylinder for inflation. The outer wall of the fixed cylinder is equipped with an inflation tube, as well as an inflation bladder and an exhaust valve that are matched with the inflation tube.

2. The mouse holder of claim 1, wherein: The fixing cylinder includes an upper fixing cylinder and a lower fixing cylinder. The upper fixing cylinder and the lower fixing cylinder are provided with connecting ears on both sides, and the connecting ears are connected by adhesive. The lower fixing cylinder is connected to the support plate.

3. The mouse restraint device according to claim 2, characterized in that: The head sleeve includes an upper head sleeve and a lower head sleeve, with the ends of the upper head sleeve and the lower head sleeve connected to the upper fixed sleeve and the lower fixed sleeve, respectively.

4. A mouse restraint device according to claim 3, characterized in that: The ends of the upper sleeve and the lower sleeve are integrally formed and connected to the upper fixed cylinder and the lower fixed cylinder, respectively.

5. A mouse restraint device according to claim 4, characterized in that: The airbag includes a cylindrical rubber surface, with both ends of the rubber surface fitted onto a stiffened flange, the edge of which is tightly connected to the inside of the fixed cylinder.

6. A mouse restraint device according to claim 5, characterized in that: The upper and lower fixed cylinders are each provided with a semi-circular sealing groove, and the stiffened flange is embedded in the sealing groove and tightly connected to the inside of the fixed cylinder.

7. A mouse restraint device according to claim 6, characterized in that: The stiffened flange is provided with an annular limiting groove, and an annular elastic ring is sleeved on the outside of the rubber surface, with the elastic ring embedded in the limiting groove.

8. A mouse restraint device according to claim 7, characterized in that: There are four elastic rings, which are respectively located at both ends of the rubber surface.

9. A mouse restraint device according to any one of claims 1-8, characterized in that: All components are made of transparent material.

Citation Information

Patent Citations

  • Mouse fixator

    CN208808716U