Biological sample sampling and detecting integrated device

Abstract

This invention provides an integrated biological sample collection and testing device, relating to the field of biological sample collection technology. The container body contains a liquid-containing cavity, a test strip holder mounting cavity, and a drainage channel. A sealing membrane is provided between the distal end of the liquid-containing cavity and the drainage channel. A sampling rod is inserted into the liquid-containing cavity, with a blade at the distal end and a limiting block connected to the proximal end. A sealing structure is provided on the outer wall. The limiting block is positioned on the inner wall of the container lid via a first positioning structure. The container lid seals the proximal side of the container body and is further positioned on the container body via a second positioning structure, so that the blade of the sampling rod is suspended near the proximal end of the sealing membrane. This invention enables dry and wet separation, effectively improving the convenience and stability of the device during carrying, storage, and transportation. It facilitates rapid on-site testing, improves the accuracy and reliability of test results, and is simple in structure and easy to operate.

Description

Technical Field

[0001] This utility model relates to the field of biological sample sampling technology, and in particular to an integrated device for biological sample sampling and detection. Background Technology

[0002] With the rapid development of medical diagnostic technology, point-of-care testing is becoming increasingly widely used in clinical diagnosis and home health monitoring. Traditional biosample testing usually requires sending samples to a professional laboratory for analysis, a process involving multiple steps and stages.

[0003] In existing technologies, biological sample collection typically utilizes box-shaped storage dishes, primarily for temporary sample storage and transportation. After collection, the sample needs to be diluted by a technician before being added to the reaction chamber, and results can only be observed after several minutes of reaction time. This separation of sampling and detection results in a significant time lag between sample collection and analysis, increasing the risk of sample contamination or spoilage. Furthermore, in traditional testing devices, reagents and test strips are stored separately. This design not only increases operational complexity but also makes the device prone to liquid leakage during carrying, storage, and transportation, further affecting the accuracy and reliability of test results. Utility Model Content

[0004] The purpose of this invention is to provide an integrated biological sample collection and testing device to alleviate the aforementioned technical problems in the prior art.

[0005] To achieve the above objectives, the embodiments of this utility model adopt the following technical solutions: This utility model provides an integrated device for biological sample collection and detection, comprising: The container body has radially separated liquid-containing cavities and test strip holder mounting cavities inside. Along the axial direction of the container body, the container body has a proximal end and a distal end. The distal end of the container body has a drainage channel inside. The distal end of the test strip holder mounting cavity communicates with the drainage channel. The container body has a test strip mounting channel that communicates with the test strip holder mounting cavity and can be opened and closed. A sealing membrane is provided between the distal end of the liquid-containing cavity and the drainage channel to separate the liquid-containing cavity and the drainage channel. The proximal end of the container body has a sampling port that communicates with the liquid-containing cavity. A sampling rod is inserted into the liquid-containing cavity, with a blade at its distal end and a limiting block fixedly connected to its proximal end; the outer wall of the sampling rod is provided with a sealing structure to seal the gap between the outer wall of the sampling rod and the inner wall of the liquid-containing cavity when the sampling rod is inserted into the liquid-containing cavity, thereby dividing the liquid-containing cavity into two parts: a proximal side cavity and a distal side cavity; The container cap and the limiting block are positioned on the inner wall of the container cap by a first positioning structure. The container cap covers the proximal side of the container body and is positioned on the container body by a second positioning structure, so that the blade is suspended on the proximal side of the sealing membrane. When the sampling rod is inserted into the liquid containing cavity and detached from the container cap, the blade cuts the sealing membrane when the limiting block is pressed in the distal direction.

[0006] In an optional embodiment, the first positioning structure includes a limiting groove, a positioning protrusion, and a blocking rib. The limiting block has a circular cross-section along the radial direction of the sampling rod, and the limiting groove is provided on the outer peripheral surface of the limiting block and extends along the circumferential direction of the limiting block; The positioning protrusion is provided on the inner peripheral wall of the container lid, and the surface of the positioning protrusion facing the limiting block when the limiting block is positioned on the container lid is an arc-shaped concave surface that fits against the outer peripheral wall of the limiting block. The blocking rib is provided on the inner wall surface of the container lid and / or the arc-shaped concave surface; The limiting block can rotate relative to the container lid to screw the blocking rib into the limiting groove.

[0007] In an optional embodiment, at least two limiting grooves are evenly spaced along the outer periphery of the limiting block, and the number of blocking ribs is the same as that of the limiting grooves and they are arranged one-to-one on the container lid.

[0008] In an optional embodiment, the second positioning structure includes a second blocking rib disposed on the inner wall of the container lid and a first positioning rib disposed on the outer peripheral wall of the near end of the container body. When the container lid is sealed on the near end side of the container body, the second blocking rib blocks the far end side of the first positioning rib.

[0009] In an optional embodiment, the container body includes a sleeve, which is inserted into and fixed to the container body through the sampling port, the inner cavity of the sleeve forms the liquid containing cavity, and the sealing film covers the distal end of the sleeve; the sampling rod is inserted into the sleeve through the sampling port.

[0010] In an optional embodiment, a limiting tube is fixed to the inner wall of the container body and extends through the axial direction of the container body, and the sleeve is inserted into the limiting tube. A limiting rib one is provided on the inner sidewall of the proximal end of the limiting tube; a limiting rib two is provided on the outer sidewall of the proximal end of the sleeve; a limiting step is provided on the outer sidewall of the sleeve; the limiting rib two abuts against the proximal end side of the limiting rib one, and the limiting step abuts against the distal end side of the distal end face of the limiting tube.

[0011] In an optional embodiment, the sealing structure includes a conical sealing ring fixedly connected to the outer peripheral wall of the sampling rod and a limiting fitting part provided on the inner side wall of the sleeve; The limiting mating part is provided with an axially penetrating limiting through hole, and the inner sidewall of the limiting through hole includes a tapered sealing surface with a diameter that gradually decreases from the proximal end to the distal end. When the sampling rod is inserted into the liquid containing cavity, the outer peripheral wall of the conical sealing ring fits against the conical sealing surface.

[0012] In an optional embodiment, the sampling rod includes a proximal section, a threaded structure section, and a distal section connected sequentially from the proximal end to the distal end; the cutting edge is fixedly connected to the distal side of the distal section, the threaded structure section has multiple turns of external thread to form a sample groove, and the sealing structure is provided on the proximal section.

[0013] In an optional embodiment, a test strip holder is installed inside the test strip holder mounting cavity. The test strip holder is provided with at least one test strip mounting groove. The two side walls of the test strip mounting groove extending axially are respectively provided with at least one nail-shaped positioning part protruding into the test strip mounting groove for positioning the test strip.

[0014] In an optional embodiment, the container body includes a tubular body and a base; The liquid-containing cavity and the test strip holder mounting cavity are located inside the tubular body; The base includes a bottom wall and a peripheral wall, and the drainage channel is located inside the space enclosed by the bottom wall and the peripheral wall; The distal end of the tubular body is sealed to the peripheral wall of the base.

[0015] The embodiments of this utility model can achieve at least the following beneficial effects: The plug-in limiting biological sample collection and testing integrated device provided in this embodiment of the utility model effectively improves the convenience and stability of the device during carrying, storage and transportation by integrating reagents (or sample solutions) and test strips into the same device, making it easy to achieve rapid on-site testing.

[0016] Furthermore, by setting up a synergistic structure of sealing membrane, container lid and limiting block, it is ensured that the blade of the sampling rod will not accidentally contact and puncture the sealing membrane before testing, thereby avoiding leakage of reagents in the liquid container cavity in the non-testing state, ensuring that the test strip holder mounting cavity is always in a dry state before testing, realizing a reliable state of dry and wet separation, which can improve the accuracy and reliability of test results.

[0017] In actual operation, users only need to remove the limiting block from the container lid to start the testing process. The operation steps are simple and the response is rapid, which greatly shortens the time interval between sample collection and analysis, reduces the risk of sample being contaminated by the outside world after collection, and thus further improves the accuracy and reliability of the test results.

[0018] In addition, the overall structural design of this embodiment is simple, with few parts and easy assembly process, which not only reduces manufacturing costs but also improves production efficiency.

[0019] Specifically, in the present invention, the term "and / or" indicates that the structure before "and / or" and the structure after "and / or" are set simultaneously or selectively. Attached Figure Description

[0020] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0021] Figure 1 A schematic diagram of the overall structure of the integrated biological sample collection and detection device provided in this embodiment of the utility model; Figure 2 An exploded view of the overall structure of the integrated biological sample collection and detection device provided in this embodiment of the utility model; Figure 3 A schematic diagram of the overall structure of the container lid in the integrated biological sample collection and testing device provided in this embodiment of the utility model; Figure 4 A schematic diagram of the overall structure of the sampling rod in the integrated biological sample collection and detection device provided in this embodiment of the utility model; Figure 5 A schematic diagram of the overall structure of the sleeve in the integrated biological sample collection and detection device provided in this embodiment of the utility model. Figure 1 ; Figure 6 A schematic diagram of the overall structure of the sleeve in the integrated biological sample collection and detection device provided in this embodiment of the utility model. Figure 2 ; Figure 7 A schematic diagram of the overall structure of the tubular main body of the container in the integrated biological sample collection and testing device provided in this embodiment of the utility model. Figure 1 ; Figure 8A schematic diagram of the overall structure of the tubular main body of the container in the integrated biological sample collection and testing device provided in this embodiment of the utility model. Figure 2 ; Figure 9 A schematic diagram of the overall structure of the base in the integrated biological sample collection and detection device provided in this embodiment of the utility model; Figure 10 A schematic diagram of the overall structure of the test strip holder in the integrated biological sample collection and testing device provided in this embodiment of the utility model.

[0022] Icons: 1-Container body; 11-Tubular body; 111-Positioning rib 1; 112-Blocking rib 3; 12-Base; 121-Positioning rib 2; 122-Limiting rib; 101-Liquid receiving cavity; 102-Test paper holder mounting cavity; 103-Drainage channel; 1031-Drainage guide slope; 104-Sealing membrane; 2-Sampling rod; 201-Threaded structure section; 21-Knife edge; 22-Limiting block; 221-Limiting groove; 31-Conical sealing ring; 32-Limiting mating part; 321-Conical sealing surface; 4-Container cap; 41-Blocking rib 1; 42-Positioning protrusion; 43-Blocking rib 2; 5-Sleeve; 51-Limiting rib 2; 52-Limiting step; 6-Limiting tube; 61-Limiting rib 1; 7-Test paper holder; 71-Test paper mounting groove; 72-Nail-shaped positioning part; 8-Test paper strip. Detailed Implementation

[0023] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. The components of the embodiments of this utility model described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0024] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0025] It should be noted that similar labels and letters in the accompanying drawings indicate similar items. Therefore, once an item is defined in one accompanying drawing, it does not need to be further defined and explained in subsequent accompanying drawings.

[0026] In the description of this utility model, it should be noted that the terms "upper," "lower," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship commonly used when the utility model product is in use. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. In addition, the terms "first," "second," and "third," etc., are only used to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0027] Furthermore, the terms "horizontal" and "vertical" do not imply that the component must be absolutely horizontal or suspended, but rather that it can be slightly tilted. For example, "horizontal" simply means that its direction is more horizontal than "vertical," and does not mean that the structure must be completely horizontal, but can be slightly tilted.

[0028] In the description of this utility model, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set," "install," and "connect" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0029] The following detailed description, in conjunction with the accompanying drawings, outlines some embodiments of the present invention. Unless otherwise specified, the following embodiments and features can be combined with each other.

[0030] This embodiment provides an integrated device for biological sample collection and detection, referring to... Figures 1 to 10 The integrated biological sample collection and testing device includes a container body 1, a sampling rod 2, and a container lid 4.

[0031] The container body 1 has a liquid containing cavity 101 and a test strip holder mounting cavity 102 that are radially separated from each other. Along the axial direction of the container body 1, the container body 1 has a proximal end and a distal end. The distal end of the container body 1 has a drainage channel 103. The distal end of the test strip holder mounting cavity 102 is connected to the drainage channel 103. The container body 1 has a test strip mounting channel that is connected to the test strip holder mounting cavity 102 and can be opened and closed. A sealing membrane 104 is provided between the distal end of the liquid containing cavity 101 and the drainage channel 103 to separate the liquid containing cavity 101 and the drainage channel 103. The proximal end of the container body 1 has a sampling port that is connected to the liquid containing cavity 101.

[0032] The sampling rod 2 is inserted into the liquid containing cavity 101. The distal end of the sampling rod 2 is provided with a blade 21, and the proximal end of the sampling rod 2 is fixedly connected to a limiting block 22. The outer wall of the sampling rod 2 is provided with a sealing structure to seal the gap between the outer wall of the sampling rod 2 and the inner wall of the liquid containing cavity 101 when the sampling rod 2 is inserted into the liquid containing cavity 101, thereby dividing the liquid containing cavity 101 into two parts: a proximal side cavity and a distal side cavity.

[0033] The limiting block 22 is positioned on the inner wall of the container lid 4 by the first positioning structure. The container lid 4 is sealed on the proximal side of the container body 1, and the container lid 4 is positioned on the container body 1 by the second positioning structure, so that the blade 21 of the sampling rod 2 is suspended on the proximal side of the sealing membrane 104. When the sampling rod 2 is inserted into the liquid containing cavity 101 and is detached from the container lid 4, the blade 21 cuts the sealing membrane 104 when the limiting block 22 is pressed in the distal direction.

[0034] The assembly and usage methods of this embodiment are as follows: The sample liquid (reagent) is contained inside the liquid containing cavity 101. The test strip holder 7 is installed inside the test strip holder mounting cavity 102 (the installation method includes but is not limited to snap-fit). The test strip 8 is fixed on the test strip holder 7, and the liquid-immersed end of the test strip 8 extends into the drainage channel 103.

[0035] Initially, the container body 1 is positioned with the proximal end facing up and the distal end facing down. The sample liquid is blocked by the sealing membrane 104 and will not enter the test strip holder mounting cavity 102. The limiting block 22 is positioned on the inner wall of the container cap 4 through the first positioning structure. The container cap 4 is sealed on the proximal side of the container body 1, and the container cap 4 is positioned on the container body 1 through the second positioning structure, so that the blade 21 of the sampling rod 2 is suspended on the proximal side of the sealing membrane 104.

[0036] During sampling, the container body 1 is positioned with the proximal end facing up and the distal end facing down. The container cap 4 is removed from the container body 1, and the limiting block 22 is positioned on the inner wall of the container cap 4 through the first positioning structure. The sampling rod 2 is used to take the sample. After sampling, the sampling rod 2 with the sample is reinserted into the liquid containing cavity 101 along the sampling port. The container cap 4 is sealed on the proximal side of the container body 1, and the container cap 4 is positioned on the container body 1 through the second positioning structure, so that the blade 21 of the sampling rod 2 is suspended on the proximal side of the sealing film 104, so that the sample is fully lysed. During testing, the container cap 4 is removed from the container body 1, and the limiting block 22 is disengaged from the container cap 4 to release the sampling rod 2. The limiting block 22 is pressed towards the distal end, causing the blade 21 at the distal end of the sampling rod 2 to cut the sealing membrane 104. The lysed sample liquid flows through the opening to the drainage channel 103 and contacts the liquid-immersed end of the test strip 8. A colored band appears on the reaction plate of the test strip 8, and then the reading of the test strip 8 is observed through the side wall of the liquid containing cavity 101.

[0037] In particular, the sidewalls of the liquid-containing cavity 101 are provided with observation windows or are made directly of transparent material.

[0038] The pluggable limiting biological sample collection and testing integrated device provided in this embodiment effectively improves the convenience and stability of the device during carrying, storage and transportation by integrating reagents (or sample solutions) and test strips into the same device, making it easy to achieve rapid on-site testing.

[0039] Furthermore, by setting up a synergistic structure of sealing membrane 104, container cap 4 and limiting block 22, it is ensured that the blade 21 of sampling rod 2 will not accidentally contact and puncture sealing membrane 104 before testing, thereby preventing the reagent in liquid container cavity 101 from leaking in the non-testing state, ensuring that test strip holder mounting cavity 102 is always in a dry state before testing, realizing a reliable state of dry and wet separation, which can improve the accuracy and reliability of test results.

[0040] In actual operation, users only need to detach the limiting block 22 from the container cover 4 to start the detection process. The operation steps are simple and the response is rapid, which greatly shortens the time interval between sample collection and analysis, reduces the risk of sample being contaminated by the outside world after collection, and thus further improves the accuracy and reliability of the test results.

[0041] In addition, the overall structural design of this embodiment is simple, with few parts and easy assembly process, which not only reduces manufacturing costs but also improves production efficiency.

[0042] Reference Figure 2 and Figure 3 In an optional embodiment of this example, the first positioning structure includes a limiting groove 221, a positioning protrusion 42, and a blocking rib 41. Specifically, the limiting block 22 has a circular cross-section along the radial direction of the sampling rod 2, and the limiting groove 221 is provided on the outer peripheral surface of the limiting block 22 and extends circumferentially along the limiting block 22. The positioning protrusion 42 is provided on the inner peripheral wall of the container cap 4, and the surface of the positioning protrusion 42 facing the limiting block 22 when the limiting block 22 is positioned on the container cap 4 has an arc-shaped concave surface that fits against the outer peripheral wall of the limiting block 22. The blocking rib 41 is provided on the inner wall surface of the container cap 4 and / or the aforementioned arc-shaped concave surface. The limiting block 22 can rotate relative to the container cap 4 to screw the blocking rib 41 into the limiting groove 221.

[0043] In this optional embodiment, during positioning, the limiting block 22 can be pressed into the inner cavity of the container lid 4 and then rotated to lock the limiting block 22 and the container lid 4, achieving a stable positioning effect. When it is necessary to remove the limiting block 22 from the container lid 4, simply rotate the limiting block 22 and the container lid 4 relative to each other to achieve the disengagement function. In this structure, the arc-shaped concave surface of the positioning protrusion 42 fits against the circular outer peripheral wall of the limiting block 22, ensuring stable positioning between the sampling rod 2 and the container lid 4. The blocking rib 41 is set on the inner wall surface or arc-shaped concave surface of the container lid 4, and can be screwed into the limiting groove 221 by rotating the limiting block 22, forming an effective anti-loosening locking structure to prevent loosening caused by vibration or external force during use. This design can ensure the reliability of the positioning between the limiting block 22 and the container lid 4, and is flexible and convenient to operate.

[0044] Alternatively, at least two of the aforementioned limiting grooves 221 are evenly spaced along the outer periphery of the limiting block 22, and the number of blocking ribs 41 is the same as that of the limiting grooves 221 and they are arranged one-to-one on the container lid 4 to further enhance the limiting stability.

[0045] In an optional embodiment of this example, the second positioning structure includes a second blocking rib 43 disposed on the inner wall of the container lid 4 and a first positioning rib 111 disposed on the outer peripheral wall of the near end of the container body 1. When the container lid 4 is sealed on the near end side of the container body 1, the second blocking rib 43 blocks the far end side of the first positioning rib 111. During assembly, it can be assembled by relative rotation.

[0046] In this optional embodiment, by providing a second blocking rib 43 on the inner wall of the container lid 4 and a first positioning rib 111 on the outer peripheral wall near the near end of the container body 1, when the container lid 4 is sealed on the near end side of the container body 1, the second blocking rib 43 blocks the far end side of the first positioning rib 111, thereby ensuring precise positioning between the container lid 4 and the container body 1. This design effectively prevents the container lid 4 from loosening due to vibration or external force during use, improves the stability and reliability of positioning between the container lid 4 and the container body 1, and provides a positioning point for the container lid 4 relative to the axial direction of the container body 1, ensuring that when the limiting block 22 is positioned on the container lid 4, the blade 21 of the sampling rod 2 will not pierce the sealing membrane 104, improving the sealing reliability of the liquid receiving cavity 101 before detection.

[0047] In an optional embodiment of this example, the container body 1 includes a sleeve 5. The sleeve 5 is inserted into and fixed to the container body 1 through the sampling port. The inner cavity of the sleeve 5 forms a liquid-containing cavity 101. A sealing membrane 104 covers the distal end of the sleeve 5. The sampling rod 2 is inserted into the sleeve 5 through the sampling port. In this optional embodiment, by designing the sleeve 5 and setting the sealing membrane 104 at the distal end of the sleeve 5, a stable installation port (i.e., the distal end of the sleeve 5) is provided for the installation of the sealing membrane 104. This improves the sealing performance of the sealing membrane 104, effectively seals the liquid-containing cavity 101, further prevents sample contamination and leakage, and enhances the integrity and safety of sample preservation. The connection method of the sealing membrane 104 can be, but is not limited to, sealing the distal end of the sleeve 5 by heat pressing.

[0048] Optionally, a limiting tube 6 is fixed to the inner wall of the container body 1, extending axially along the container body 1, and the sleeve 5 is inserted into the limiting tube 6; a limiting rib 61 is provided on the inner side wall of the proximal end of the limiting tube 6; a limiting rib 51 is provided on the outer side wall of the proximal end of the sleeve 5, and a limiting step 52 is provided on the outer side wall of the sleeve 5; the limiting rib 51 abuts against the proximal side of the limiting rib 61, and the limiting step 52 abuts against the distal side of the distal end face of the limiting tube 6. During assembly, assembly can be performed by relative rotation. In this optional embodiment, the design of the limiting tube 6 provides a clear positioning and fixing point for the sleeve 5 inside the container body 1. Combined with the abutting design of the first limiting rib 61 and the second limiting rib 51, as well as the abutting design of the limiting step 52 and the far end face of the limiting tube 6, the position of the sleeve 5 inside the container body 1 can be fixed and stable, avoiding displacement or falling off during use, thus improving the structural stability of the overall device. Furthermore, this design simplifies the assembly process, reduces assembly time and complexity, and improves the production efficiency of the device.

[0049] Reference Figure 4 , Figure 5 and Figure 6 In this embodiment, the outer wall of the sampling rod 2 is provided with a sealing structure, which can seal the gap between the outer wall of the sampling rod 2 and the inner wall of the liquid containing cavity 101 when the sampling rod 2 is inserted into the liquid containing cavity 101, thereby dividing the liquid containing cavity 101 into two parts: a proximal side cavity and a distal side cavity, thereby preventing the sample liquid from evaporating and avoiding leakage. This sealing structure has various design forms, including but not limited to a structure in which an O-ring is fitted on the outside of the sampling rod 2.

[0050] In some preferred embodiments of this example, such as Figure 4 and Figure 6As shown, the sealing structure on the outer wall of the sampling rod 2 includes a conical sealing ring 31 fixedly connected to the outer peripheral wall of the sampling rod 2 and a limiting fitting part 32 provided on the inner side wall of the sleeve 5. The limiting fitting part 32 is provided with an axially penetrating limiting through hole, and the inner side wall of the limiting through hole includes a conical sealing surface 321 whose diameter gradually decreases from the proximal end to the distal end. When the sampling rod 2 is inserted into the liquid receiving cavity 101, the outer peripheral wall of the conical sealing ring 31 fits against the conical sealing surface 321. In this embodiment, the fitting design of the conical sealing ring 31 and the conical sealing surface 321 of the limiting fitting part 32 reduces the gap between the sealing ring and the inner side wall of the sleeve 5. Furthermore, when the conical sealing ring 31 is under pressure, its conical surface will be uniformly compressed axially, forming a multi-point contact sealing surface with the conical sealing surface 321, thereby improving the reliability and stability of the seal.

[0051] Reference Figure 4 In an optional embodiment of this example, the sampling rod 2 includes a proximal section, a threaded structure section 201, and a distal section connected sequentially from the proximal end to the distal end; the blade 21 is fixedly connected to the distal side of the distal section, and the threaded structure section 201 has multiple external threads forming sample grooves, with the aforementioned sealing structure located on its proximal section. In this optional embodiment, the threaded structure section 201 provides multiple sample grooves, which is more conducive to retaining the sample on the sampling rod 2.

[0052] Reference Figure 10 In an optional embodiment of this example, a test strip holder 7 is installed inside the test strip holder mounting cavity 102. The test strip holder 7 is provided with at least one test strip mounting groove 71. The two side walls of the test strip mounting groove 71 extending axially are respectively provided with at least one nail-shaped positioning part 72 protruding into the test strip mounting groove 71. These nail-shaped positioning parts 72 are used to position the test strip 8.

[0053] Reference Figure 7 , Figure 8 and Figure 9In an optional embodiment of this example, the container body 1 includes a tubular body 11 and a base 12; a liquid containing cavity 101 and a test strip holder mounting cavity 102 are disposed inside the tubular body 11; the base 12 includes a bottom wall and a peripheral wall, and a drainage channel 103 is disposed inside the space enclosed by the bottom wall and the peripheral wall; the distal end of the tubular body 11 is sealed to the peripheral wall of the base 12. In this optional embodiment, the base 12 can be positioned by, but is not limited to, a third blocking rib 112 disposed on the inner peripheral wall of the tubular body 11 and a second positioning rib 121 disposed on the outer peripheral wall of the base 12. During assembly, it can be assembled by relative rotation. In the assembled state, the third blocking rib 112 abuts against the distal end of the second positioning rib 121 to achieve a tight connection between the two. The base 12 has a limiting rib 122 on its inner bottom wall to form a drainage channel 103. The surface of the drainage channel 103 forms a drainage guide slope 1031. The height of the drainage guide slope 1031 on the side near the liquid receiving cavity 101 is higher than the height on the side near the test strip holder mounting cavity 102. This allows the lysed sample liquid to be quickly guided to the test strip holder mounting cavity 102 after the far end of the sampling rod 2 pierces the sealing membrane 104, so that the lysed sample liquid can fully contact the liquid-immersed end of the test strip 8, further improving the detection efficiency and the accuracy of the detection results.

[0054] Specifically, when the base 12 is provided, the part where the test strip holder mounting cavity 102 and the base 12 are connected can be regarded as a test strip mounting channel provided on the container body 1 that communicates with the test strip holder mounting cavity 102 and can be opened and closed. The test strip holder 7 can be installed inside the test strip holder mounting cavity 102 by removing the base 12. The installation method includes, but is not limited to, setting a snap-fit ​​structure on the inner wall of the test strip holder mounting cavity 102 to snap the test strip holder 7 onto the inner wall of the test strip holder mounting cavity 102.

[0055] Finally, it should be noted that: 1. In this specification, "and / or" means that the structure before "and / or" and the structure after "and / or" are set simultaneously or selectively; 2. The various embodiments in this specification are described in a progressive manner, with each embodiment focusing on the differences from other embodiments. Similar or identical parts between embodiments can be referred to mutually. The above embodiments in this specification are only used to illustrate the technical solutions of this utility model and are not intended to limit it. Although this utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the various embodiments of this utility model.

Claims

1. An integrated device for biological sample collection and detection, characterized in that, include: The container body has radially separated liquid-containing cavities and test strip holder mounting cavities inside. Along the axial direction of the container body, the container body has a proximal end and a distal end. The distal end of the container body has a drainage channel inside. The distal end of the test strip holder mounting cavity communicates with the drainage channel. The container body has a test strip mounting channel that communicates with the test strip holder mounting cavity and can be opened and closed. A sealing membrane is provided between the distal end of the liquid-containing cavity and the drainage channel to separate the liquid-containing cavity and the drainage channel. The proximal end of the container body has a sampling port that communicates with the liquid-containing cavity. A sampling rod is inserted into the liquid-containing cavity, with a blade at its distal end and a limiting block fixedly connected to its proximal end; the outer wall of the sampling rod is provided with a sealing structure to seal the gap between the outer wall of the sampling rod and the inner wall of the liquid-containing cavity when the sampling rod is inserted into the liquid-containing cavity, thereby dividing the liquid-containing cavity into two parts: a proximal side cavity and a distal side cavity; The container cap and the limiting block are positioned on the inner wall of the container cap by a first positioning structure. The container cap covers the proximal side of the container body and is positioned on the container body by a second positioning structure, so that the blade is suspended on the proximal side of the sealing membrane. When the sampling rod is inserted into the liquid containing cavity and detached from the container cap, the blade cuts the sealing membrane when the limiting block is pressed in the distal direction.

2. The device according to claim 1, wherein The first positioning structure includes a limiting groove, a positioning protrusion, and a blocking rib. The limiting block has a circular cross-section along the radial direction of the sampling rod, and the limiting groove is provided on the outer peripheral surface of the limiting block and extends along the circumferential direction of the limiting block; The positioning protrusion is provided on the inner peripheral wall of the container lid, and the surface of the positioning protrusion facing the limiting block when the limiting block is positioned on the container lid is an arc-shaped concave surface that fits against the outer peripheral wall of the limiting block. The blocking rib is provided on the inner wall surface of the container lid and / or the arc-shaped concave surface; The limiting block can rotate relative to the container lid to screw the blocking rib into the limiting groove.

3. The integrated biological sample sampling and testing device of claim 2, wherein, At least two limiting grooves are evenly spaced along the outer periphery of the limiting block, and the number of blocking ribs is the same as that of the limiting grooves and they are arranged one-to-one on the container lid.

4. The integrated biological sample collection and detection device according to claim 1, characterized in that, The second positioning structure includes a second blocking rib on the inner wall of the container lid and a first positioning rib on the outer peripheral wall near the near end of the container body. When the container lid is closed on the near end side of the container body, the second blocking rib blocks the far end side of the first positioning rib.

5. The integrated biological sample collection and detection device according to claim 1, characterized in that, The container body includes a sleeve, which is inserted into the container body through the sampling port and fixed to the container body. The inner cavity of the sleeve forms the liquid containing cavity, and the sealing film covers the distal end of the sleeve. The sampling rod is inserted into the sleeve through the sampling port.

6. The integrated biological sample sampling and testing device of claim 5, wherein, A limiting tube is fixed to the inner wall of the container body and extends through the axial direction of the container body; the sleeve is inserted into the limiting tube. A limiting rib one is provided on the inner sidewall of the proximal end of the limiting tube; a limiting rib two is provided on the outer sidewall of the proximal end of the sleeve; a limiting step is provided on the outer sidewall of the sleeve; the limiting rib two abuts against the proximal end side of the limiting rib one, and the limiting step abuts against the distal end side of the distal end face of the limiting tube.

7. The integrated biological sample collection and detection device according to claim 5, characterized in that, The sealing structure includes a conical sealing ring fixedly connected to the outer peripheral wall of the sampling rod and a limiting fitting part provided on the inner side wall of the sleeve; The limiting mating part is provided with an axially penetrating limiting through hole, and the inner sidewall of the limiting through hole includes a tapered sealing surface with a diameter that gradually decreases from the proximal end to the distal end. When the sampling rod is inserted into the liquid containing cavity, the outer peripheral wall of the conical sealing ring fits against the conical sealing surface.

8. The integrated biological sample collection and detection device according to claim 1, characterized in that, The sampling rod includes a proximal section, a threaded structure section, and a distal section connected sequentially from the proximal end to the distal end; the cutting edge is fixedly connected to the distal side of the distal section, the threaded structure section has multiple external threads forming a sample groove, and the sealing structure is provided on the proximal section.

9. The integrated biological sample collection and detection device according to claim 1, characterized in that, The test strip holder is installed inside the test strip holder mounting cavity. The test strip holder is provided with at least one test strip mounting groove. The two side walls of the test strip mounting groove extending axially are respectively provided with at least one nail-shaped positioning part protruding into the test strip mounting groove for positioning the test strip.

10. The integrated biological sample collection and detection device according to claim 1, characterized in that, The container body includes a tubular body and a base; The liquid-containing cavity and the test strip holder mounting cavity are located inside the tubular body; The base includes a bottom wall and a peripheral wall, and the drainage channel is located inside the space enclosed by the bottom wall and the peripheral wall; The distal end of the tubular body is sealed to the peripheral wall of the base.

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