ENHANCEMENT OF THE EFFECT OF MODIFIED CAR T-LYMPHOCYTES THROUGH VACCINATION WITH NUCLEIC ACIDS
CY1126187T1Undetermined Publication Date: 2026-07-31TRON TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG UNIV MAINZ GEMEINNUETZIGE GMBH
View PDF 0 Cites 0 Cited by
Patent Information
- Application Number
- CY20231100425T
- Authority / Receiving Office
- CY · CY
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2015-05-11
- Filing Date
- 2023-08-23
- Publication Date
- 2026-07-31
- Estimated Expiration
- 2043-08-23
Abstract
The present invention generally involves the treatment of diseases by targeting cells expressing an antigen on the cell surface. In particular, the invention relates to a method for stimulating, activating and / or expanding in vivo T cells genetically modified to express a chimeric antigen receptor (CAR) targeting an antigen, comprising contacting the T cells with the antigen or a variant thereof in vivo. In one embodiment, the antigen or variant thereof is provided by administering nucleic acid encoding the antigen or variant thereof.
Need to check novelty before this filing date? Find Prior Art