Method for conditioning a filling device for liquid pharmaceuticals into a container and filling device for carrying out the method

Abstract

Method for conditioning a filling device (100) for liquid pharmaceuticals into a container (1), wherein the filling device (100) comprises a first filling device (10) for filling a main fill quantity and a second filling device (20) for metering a refill quantity from a difference between a total fill quantity and the main quantity and a first weighing device (31), wherein prior to a production phase (60) in which the containers (1) are filled by means of both filling devices (10, 20), a conditioning phase (40) takes place in which the total fill quantity is metered into the container (1) only by means of the second filling device (20), and wherein the conditioning phase (40), in particular for removing air bubbles in the product path of the second filling device (20), comprises the following steps at the second filling device (20): a. Performing a preconditioning phase (42) over a certain first number of filling operations at the second filling device (20), each time filling the total quantity into the containers (1). b. Performing a main conditioning phase (43) when the preconditioning phase (42) is deemed to have been successfully completed based on initial criteria, wherein in the main conditioning phase (43) a certain second number of containers (1) are filled with the total filling quantity using the second filling device (20). c. Starting the production phase (60) after the main conditioning phase (43), wherein at least one machine parameter of the second filling device (20) determined during the main conditioning phase (43) is specified as the starting value for the production phase (60). d. wherein the containers (1) filled during the preconditioning phase (42) and the main conditioning phase (43) have a total fill quantity which is within prescribed tolerances for the total fill quantity.

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